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Studies on the digestive gland structures of domestic and experimental animals I. Glandular tubule structures in the cecum and colon of piglets (가축 및 실험동물 소화선의 구조에 관한 연구 I. 돼지 맹장 및 결장 장선의 구조에 관하여)

  • Kwak, Soo-dong;Lee, Soon-sun;Moon, Oun-gyeong
    • Korean Journal of Veterinary Research
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    • v.30 no.1
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    • pp.1-8
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    • 1990
  • The present study was focussed mainly on the morphological changes of the glandular tubules in the large intestine according to age of piglets. Samples were taken from large intesine of 1-, 10-, 20-, 35- and 45-day-old piglets, 2 to 3 piglets in each age group. The intestinal samples were fixed in 10% neutral formalin solution, dehydrated, and then paraffin sections were stained with H-E. The results observed were summarized as follows: 1. The mucosal glands in the cecum and colon tend to be unbranched simple straight tubular glands, or often two or more branched simple stright tubular glands. 2. The number of the longitudinal folds and the number of the crypts per cross section of piglet colons, respectively, were 1-day-old piglets-$3.8{\pm}0.8$, $92.1{\pm}6.9$; 10-day-old piglets-$7.1{\pm}1.1$, $164.2{\pm}10.3$; 20-day-old piglets-$15.2{\pm}0.8$, $178.5{\pm}6.8$; 35-day-old piglets-$19.3{\pm}3.0$, $454.9{\pm}25.3$; 45-day-old piglets-$20.6{\pm}3.1$, $524.6{\pm}37.2$, and the regression equation between age and these two number were $\hat{Y}=0.40X+4.32$ and $\hat{Y}=10.4X+51.52$, respectively. 3. The length and cell number per single side wall of a glandular tubule in the colon section were 1-day-old piglets-$196.3{\pm}7.1{\mu}m$, $40.0{\pm}3.3$; 10-day-old piglets-$236.0{\pm}34.5{\mu}m$, $47.9{\pm}5.3$; 20-day-old piglets-$262.8{\pm}39.6{\mu}m$, $54.3{\pm}9.0$; 35-day-old piglets-$291.75{\pm}48.3{\mu}m$, $56.9{\pm}4.9$; 45-day-old piglets-$364.8{\pm}61.5{\mu}m$, $67.7{\pm}7.4$, respectively, and the regression equation between age and these two data were $\hat{Y}=3.45X+193.8$ and $\hat{Y}=0.56X+41.0$, respectively. 4. The overall percentages of the cell number and length of glandular tubules in piglet colons were the pit and isthmus-$75.3{\pm}11.1%$, $78.8{\pm}12.3%$; gland-$24.7{\pm}5.4%$, $21.2{\pm}5.3%$, respectively. 5. The length and cell number of single side wall of glandular tubules in cecal sections were 1-day-old piglets-$190.3{\pm}31.1{\mu}m$, $37.6{\pm}4.8$; 10-day-old piglets-$235.6{\pm}25.3{\mu}m$, $46.2{\pm}3.6$; 20-day-old piglets-$295.3{\pm}45.6{\mu}m$, $52.0{\pm}6.2$; 35-day-old piglets-$351.3{\pm}28.3{\mu}m$, $60.4{\pm}8.5$; 45-day-old piglets-$366.3{\pm}48.5{\mu}m$, $64.7{\pm}8.2$, respectively, and the regression equation between age and these two data were $\hat{Y}=4.11X+196.6$ and $\hat{Y}=0.60X+38.9$, respectively.

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Interstitial Hyperthermia by Radiofrequency Needle Electrode System : Phantom and Canine Brain Studies (8 MHz 라디오파를 이용한 자입식 온열치료 -조직등가물질을 통한 온도분포 및 개 뇌실질의 조직병리 변화에 관한 연구-)

  • Lee, Hyung-Sik;Chu, Sung-Sil;Sung, Jin-Sil;Suh, Chang-Ok;Kim, Gwi-Eon;Loh-John-Juhn-Kyu;Kim, Young-Soo;Kim, Sun-Ho;Chung, Song-Sup;Han, Eun-Kyung;Kim, Tae-Seung
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.27-35
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    • 1991
  • An interstitial radiofrequency needle electrode system was constructed for interstitial heating of brain tissue. Radiofrequency electrodes with Thermotron RF 8 were tested in an agar phantom and in a normal canine brain to determine how variations in physical factors affected temperature distributions. Temperature distributions were checked after heating with 1 mm diameter needle electrode implants on the corners of 1 and 2 cm squares in a phantom and plot isotherms for various electrodes arrangement. We observed that the 1 cm square array would heat a volume with a 1.25 cm radius circular field cross section to therapeutic temperatures ($90\%$ relative SAR using Tm) and the 2 cm square array with a 1.75 cm radius rectangular field with central inhomogeneity. With 2 cm long electrode implants, we observed that the 1 cm square array would heat a 3 cm long sagittal section to therapeutic temperature ($90\%$ relative SAR using Tm). We found that radiofrequency electrodes could be selected to match the length of the heating area without affecting its performance. The histopathological changes associated with RF heating of normal canine brains have been correlated with thermal distributions. RF needle electrode heating was applied for 50min to generate tissue temperatures of $43^{\circ}C$. We obtained a quarter of the heated tissue material immediately after heating and sacrificed at intervals from $7\sim30$days. The acute stage (immediately after heating) was demonstrated by liquefactive necrosis, pyknosis of neuronal element in the gray matter and by some polymer-phonuclear leukocytes infiltration. The appearance of lipid-laden macrophages surrounding the area of liquefaction necrosis was demonstrated in all three sacrificed dogs. Mild gliosis occurring around the necrosis was demonstrated in the last sacrificed (Days 30) canine brain.

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Performance Evaluation of High Strength Lattice Girder by Structural Analyses and Field Measurements (구조해석과 현장계측에 의한 고강도 격자지보재의 성능 평가)

  • Lee, Jeo-Won;Min, Kyong-Nam;Jeong, Ji-Wook;Roh, Byoung-Kuk;Lee, Sang-Jin;Ahn, Tae-Bong;Kang, Seong-Seung
    • The Journal of Engineering Geology
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    • v.30 no.3
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    • pp.237-251
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    • 2020
  • This study examined structural analysis of supports in tunnel and displacement and underground stress of tunnel by measurement, in order to evaluate the performance of high-strength lattice girders developed as a substitute for H-profiles. According to the three-dimensional nonlinear structural analysis results of the tunnel support, the load and displacement relationship between the H-profiles and the high-strength lattice girders showed almost the same behavior, and the maximum load of the high-strength lattice girders were 1.0 to 1.2 times greater than the H-profiles. By the results of the three-dimensional tunnel cross-section analysis of the supports, the axial force was occurred largely in the lower left and right sides of the tunnel, and showed a similar trend to the field test values. In the results of the measurement of the roof settlement and rod extension, the final displacement of the steel arch rib (H-profile) and high-strength lattice girder section in tunnel was converged to a constant value without significant difference within the first management standard of 23.5 mm. According to the results of underground displacement measurement, the final change amount of the two support sections showed a slight displacement change, but converged to a constant value within the first management standard of 10 mm. By the results of measurement of shotcrete stress and steel arch rib stress, the final change amount of the two support sections showed a slight stress change, but converged to a constant value within the first management standard of 81.1 kg/㎠ and 54.2 tonf.

CUTTING EFFICACY OF Er:YAG LASER AND CONVENTIONAL BUR IN DECIDUOUS AND PERMANENT TEETH (Er:YAG laser와 Conventional bur의 유치와 영구치 치아삭제효과 비교)

  • Park, In-Cheon;Lee, Chang-Seop;Lee, Nan-Young;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.30 no.2
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    • pp.272-285
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    • 2003
  • This study was conducted to observe the microscopic structures of cavities formed after ablation of primary teeth, permanent teeth, enamel and dentin in using a bur and cavities formed after ablation using laser and the following results were obtained after comparing the effects of ablation. Using a #330 bur and Er:YAG laser irradiated at 150 mJ, 200 mJ, 250 mJ and 300 mJ all at the frequency of 5 Hz, 1 mm enamel and dentin samples were ablated and the ablation time was measured. In order to measure the surfaces ablated, 5 each of primary teeth and permanent teeth were ablated using a #330 bur and Er:YAG laser at 150 mJ, 200 mJ, 250 mJ and 300 mJ for 1 sec and the cross section and vertical section were observed. The following results were obtained : 1. Cutting time of Er:YAG laser was longer than that of conventinal high-speed bur regardless of teeth type. 2. Cutting on enamel, Cutting time of conventional high-speed bur in deciduous teeth was longer than in permanent teeth(P<0.05). But Er:YAG laser was not showed any difference between the deciduous and permanent teeth(P>0.05). 3. Cutting on dentin, Cutting time of conventional high-speed bur in permanent teeth was longer than deciduous teeth. Er:YAG laser of 150 mJ, 5 Hz in permanent teeth was longer than in deciduous teeth(p<0.05). But laser of other power did not showed mean difference. 4. The cavity surface treated with the convetional high-speed bur revealed a relatively flat appearance, almost covered with a debris-like smear layer. Cavity wall showed striped appearance because of blade of bur. 5. The cavity surface treated by the Er:YAG laser system was irregular or rough surface with the absence charring, carbonization, or cracking of the dentin. In addition, there was an absence of a smear layer. Cavity floor was round and relatively smooth. According to these results, cutting time of Er:YAG laser was almostly same in permanent and deciduous teeth, but more effective in dentin than enamel. Cutting the sample, Er:YAG laser was needed more time than conventional bur. But SEM findings suggested that laser device produced favorable surface characteristic(i.e, no smear layer, irregular surface, cracking).

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Characteristics of Channelbed and Woody Debris on Mountainous Stream (산지급류소하천(山地急流小河川)에 있어서 하상미지형(河床微地形)과 유목(流木) 특성(特性))

  • Chun, Kun-Woo;Kim, Min-Sik;Park, Wan-Geun;Ezaki, Tsugio
    • Journal of Korean Society of Forest Science
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    • v.86 no.1
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    • pp.69-79
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    • 1997
  • The purpose of this study is to acquire essential data to reduce the amount of woody debris resulted from the debris flow. This research examined topographic characteristics of the channelbed affecting generation, movement and storage of woody debris and woody characteristics related to number, sizes, shapes, decay, storage direction to mountainous stream. 1. The number of woody debris had a tendency to increase in proportion to stream width, but it was hardly affected by longitudinal gradient of stream. Especially, the greater amount of woody debris was stored at wide section of the stream with compound channel, and it was found in deposits of channelbed rather than in the present channel. 2. Total woody debris over 10cm in diameter and over 2m in length was 402 units and storage number was 35.3 units per 100m of stream. Average diameter of breast height and length were 14cm and 4m, respectively. The woody debris appeared shorter in length and greater in diameter at down-stream than up-stream. 3. Since woody debris met sediments and bed-materials of great roughness in moving, the greater amount of woody debris without root was found in up-stream and down-stream, but deformed woody debris was discovered in upper stream. Decay of woody debris was more severe in down-stream and woody debris on rotting process was found down-stream. 4. Storage direction of woody debris was mainly parallel to center line of stream, and rate of parallel and perpendicularity was 276 and 126 units, respectively. But, as woody debris storing to the perpendicular direction was unstable, the traveling debris could easily be stored. Therefore, some counterplan was required to prevent the traveling woody debris. 5. Tree species of woody debris was mainly larch, which occupied about two third of total woody debris(256 units). The woody debris of larch is easy to move due to hitting of channelbed materials or lower channelbed fluctuation because the lower part of larch is weaker than its upper part. Therefore, the section of the tree species planting in the riparian vegetation needs much more carefulness.

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Evaluation of applicability of linkage modeling using PHABSIM and SWAT (PHABSIM과 SWAT을 이용한 연계모델링 적용성 평가)

  • Kim, Yongwon;Byeon, Sangdon;Park, Jinseok;Woo, Soyoung;Kim, Seongjoon
    • Journal of Korea Water Resources Association
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    • v.54 no.10
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    • pp.819-833
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    • 2021
  • This study is to evaluate applicability of linkage modeling using PHABSIM (Physical Habitat Simulation System) and SWAT (Soil and Water Assessment Tool) and to estimate ecological flow for target fishes of Andong downstream (4,565.7 km2). The SWAT was established considering 2 multi purpose dam (ADD, IHD) and 1 streamflow gauging station (GD). The SWAT was calibrated and validated with 9 years (2012 ~ 2020) data of 1 stream (GD) and 2 multi-purpose dam (ADD, IHD). For streamflow and dam inflows (GD, ADD and IHD), R2, NSE and RMSE were 0.52 ~ 0.74, 0.48 ~ 0.71, and 0.92 ~ 2.51 mm/day respectively. As a result of flow duration analysis for 9 years (2012 ~ 2020) using calibrated streamflow, the average Q185 and Q275 were 36.5 m3/sec (-1.4%) and 23.8 m3/sec (0%) respectively compared with the observed flow duration and were applied to flow boundary condition of PHABSIM. The target stream was selected as the 410 m section where GD is located, and stream cross-section and hydraulic factors were constructed based on Nakdong River Basic Plan Report and HEC-RAS. The dominant species of the target stream was Zacco platypus and the sub-dominant species was Puntungia herzi Herzenstein, and the HSI (Habitat Suitability Index) of target species was collected through references research. As the result of PHABSIM water level and velocity simulation, error of Q185 and Q275 were analyzed -0.12 m, +0.00 m and +0.06 m/s, +0.09 m/s respectively. The average WUA (Weighted Usable Area) and ecological flow of Zacco platypus and Puntungia herzi Herzenstein were evaluated 76,817.0 m2/1000m, 20.0 m3/sec and 46,628.6 m2/1000m, 9.0 m3/sec. This results indicated Zacco platypus is more adaptable to target stream than Puntungia herzi Herzenstein.

Evaluation for Rock Cleavage Using Distribution of Microcrack Lengths and Spacings (3) (미세균열의 길이 및 간격 분포를 이용한 결의 평가(3))

  • Park, Deok-Won;Park, Eui-Seob;Jung, Yong-Bok;Lee, Tae-Jong;Song, Yoon-Ho
    • The Journal of the Petrological Society of Korea
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    • v.28 no.1
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    • pp.1-13
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    • 2019
  • The characteristics of the rock cleavage of Jurassic Geochang granite were analysed using the parameters from the length and spacing-cumulative frequency diagrams. The evaluation for three planes and three rock cleavages was performed using the 25 parameters such as (1~2) slope angle(${\alpha}^{\circ}$and ${\beta}^{\circ}$), (3) intersection angle(${\alpha}-{\beta}^{\circ}$), (4) exponent difference(${\lambda}_S-{\lambda}_L$), (5~12) length of line(oa, ob, ol, os, ss', ll' and sl') and (13~15) length ratio(ol/os, ss'/ll' and ll'/sl'), (16) mean length((ss'+ll')/2), (17~23) area (${\Delta}oaa^{\prime}$, ${\Delta}obb^{\prime}$, ${\Delta}obb^{\prime}$, ${\Delta}oaa_a^{\prime}$, ${\Delta}obb_a^{\prime}$, ${\Delta}ll^{\prime}s^{\prime}$, ${\Delta}ss^{\prime}l^{\prime}$ and ⏢$ll^{\prime}ss^{\prime}$) and (24~25) area difference(${\Delta}obb^{\prime}-{\Delta}oaa^{\prime}$ and ${\Delta}obb_a^{\prime}-{\Delta}oaa_a^{\prime}$). Firstly, the values of the 11 parameters(group I: No. 1, 3~4, 7, 9~10, 13, 15~16, 20 and 25), the 3 parameters(group II: No. 5, 8 and 17) and the 2 parameters(group III: No. 12 and 22) are in orders of H(hardway) < G(grain) < R(rift), R < G < H and G < H < R, respectively. On the contrary, the values of parameters belonging to the above three groups show reverse orders for three planes. Secondly, the generalized chart for three planes and three rock cleavages were made. From the related chart, the distribution types formed by the two diagrams related to lengths and spacings were derived. The diagrams related to spacings show upward curvature in the chart of rift plane(G1 & H1, R') and hardway(H1 & H2, H). On the contrary, the diagrams related to lengths show downward curvature. These two diagrams take the form of a convex lens in the upper section. Besides, the two diagrams cross each other in the lower section. The overall shape formed by the above two diagrams between three planes($H^{\prime}{\rightarrow}G^{\prime}{\rightarrow}R^{\prime}$) and three rock cleavages($R{\rightarrow}G{\rightarrow}H$) display in reverse order. Lastly, these types of correlation analysis is useful for discriminating three quarrying planes.

Application of microwave water surface current meter for measuring agricultural water intake (농업용수 사용량 계측을 위한 전자파 표면유속계의 적용)

  • Baek, Jongseok;Kim, Chiyoung;Lee, Kisung;Kang, Hyunwoong;Song, Jaehyun
    • Journal of Korea Water Resources Association
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    • v.53 no.12
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    • pp.1071-1079
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    • 2020
  • For integrated water management, it is essential to secure basic data such as the amount of agricultural water intake. The river water intake through the intake weir is carried out through the agricultural irrigation canal, and a method for measuring the quantity of water intake is required to suit the characteristics of the measuring points. In this study, the accuracy of the calculated flow data was determined by applying a microwave water surface current meter. The microwave water surface current meter is a method of calculating surface velocity using doppler effect, which is mainly used in high-velocities situations such as flood. Surface velocity is difficult to represent the average velocity of the entire section at low dicharges or high wind speeds, it is considered to be low in continuous utilization throughout the year, and it is necessary to verify whether the measurement using an microwave water surface curren meter is appropriate in agricultural irrigation canal. The data measured with an microwave water surface curren meter were compared with the actual flow data to calculate the intake data in agricultural irrigation canal. In agricultural irrigation canal, the low-level discharge calculated using an microwave water surface current meter at a minimum velocity of about 0.3 m/s and a minimum discharge of about 1.0 m3/s or higher was found to have a high tendency and accuracy compared to the standard discharge, especially when the high discharge was high. Although effective results can be obtained in terms of quantity at low discharge, it is deemed that subsequent studies are needed to calculate the average discharge of the cross section at low discharge, given that the trend of data is unstable. Through this study, it is suggested that it is appropriate to calculate the amount of water intake through the microwave water surface current meter in artificial waterways with a certain discharge or higher, so it is expected to be widely distributed as a method for measuring river water intake.

A fundamental study on the automation of tunnel blasting design using a machine learning model (머신러닝을 이용한 터널발파설계 자동화를 위한 기초연구)

  • Kim, Yangkyun;Lee, Je-Kyum;Lee, Sean Seungwon
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.24 no.5
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    • pp.431-449
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    • 2022
  • As many tunnels generally have been constructed, various experiences and techniques have been accumulated for tunnel design as well as tunnel construction. Hence, there are not a few cases that, for some usual tunnel design works, it is sufficient to perform the design by only modifying or supplementing previous similar design cases unless a tunnel has a unique structure or in geological conditions. In particular, for a tunnel blast design, it is reasonable to refer to previous similar design cases because the blast design in the stage of design is a preliminary design, considering that it is general to perform additional blast design through test blasts prior to the start of tunnel excavation. Meanwhile, entering the industry 4.0 era, artificial intelligence (AI) of which availability is surging across whole industry sector is broadly utilized to tunnel and blasting. For a drill and blast tunnel, AI is mainly applied for the estimation of blast vibration and rock mass classification, etc. however, there are few cases where it is applied to blast pattern design. Thus, this study attempts to automate tunnel blast design by means of machine learning, a branch of artificial intelligence. For this, the data related to a blast design was collected from 25 tunnel design reports for learning as well as 2 additional reports for the test, and from which 4 design parameters, i.e., rock mass class, road type and cross sectional area of upper section as well as bench section as input data as well as16 design elements, i.e., blast cut type, specific charge, the number of drill holes, and spacing and burden for each blast hole group, etc. as output. Based on this design data, three machine learning models, i.e., XGBoost, ANN, SVM, were tested and XGBoost was chosen as the best model and the results show a generally similar trend to an actual design when assumed design parameters were input. It is not enough yet to perform the whole blast design using the results from this study, however, it is planned that additional studies will be carried out to make it possible to put it to practical use after collecting more sufficient blast design data and supplementing detailed machine learning processes.

Hepatitis Complicated with Mycoplasma pneumoniae Infection (Mycoplasma pneumoniae 폐렴에 합병된 간염)

  • Lee, Jin-Tae;Kim, Hee-Sup;Tchah, Hann
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.4 no.2
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    • pp.207-212
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    • 2001
  • Purpose: Mycoplasma pneumoniae infection is relatively common in childhood. Its extrapulmonary manifestations have been reported so much, but hepatitis associated with it has not been studied yet until now in Korea. Methods: We performed the prospective study of 19 cases that had AST and ALT>50 IU/L respectively without evidence of hepatitis A, B, C, cytomegalovirus, and Ebstein-Barr virus infections amongst 143 patients with M. pneumoniae pneumonia who were admitted to the Department of Pediatrics, Seoul Red Cross Hospital from Jan. 1999 to Dec. 2000. Results: 1) Hepatitis occurred in 13.3% of Mycoplasma pneumoniae infection, especially in fall and winter times. The average age was 4.86 years and male to female ratio was 2.2:1. 2) Vomiting was developed in 21.1%, diarrhea in 36.8%, and hepatomegaly in 21.1%, respectively. And leukocytosis was noted in 21.1%, eosinophilia in 15.4%, anemia in 10.5%, and thrombocytosis in 5.3%, respectively. The average level of C-reactive protein was $6.34{\pm}4.82$ mg/dl. 3) There was no hyperbilirubinemia, but hypoalbuminemia was detected in 42.1%. The average serum levels of AST and ALT were $214.05{\pm}183.22$ IU/L and $284.16{\pm}286.84$ IU/L, respectively. 4) Chest radiology showed lobar or lobular consolidation in 73.7%, bronchial infiltration in 26.3%, and pleural effusion in 31.6%. 5) The average length of hospitalization was 7.9 days, and the average length of normalization of serum transaminases was 8.8 days. All patients recovered within 2 weeks completely. Conclusion: The prognosis of M. pneumoniae hepatitis is good. However, its incidence is not so low that liver function should be considerately checked in case of M. pneumoniae infection.

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