• Title/Summary/Keyword: Critical size effect

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Usefulness assessment of secondary shield for the lens exposure dose reduction during radiation treatment of peripheral orbit (안와 주변 방사선 치료 시 수정체 피폭선량 감소를 위한 2차 차폐의 유용성 평가)

  • Kwak, Yong Kuk;Hong, Sun Gi;Ha, Min Yong;Park, Jang Pil;Yoo, Sook Hyun;Cho, Woong
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.1
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    • pp.87-95
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    • 2015
  • Purpose : This study presents the usefulness assessment of secondary shield for the lens exposure dose reduction during radiation treatment of peripheral orbit. Materials and Methods : We accomplished IMRT treatment plan similar with a real one through the computed treatment planning system after CT simulation using human phantom. For the secondary shield, we used Pb plate (thickness 3mm, diameter 25mm) and 3 mm tungsten eye-shield block. And we compared lens dose using OSLD between on TPS and on simulation. Also, we irradiated 200 MU(6 MV, SPD(Source to Phantom Distance)=100 cm, $F{\cdot}S\;5{\times}5cm$) on a 5cm acrylic phantom using the secondary shielding material of same condition, 3mm Pb and tungsten eye-shield block. And we carried out the same experiment using 8cm Pb block to limit effect of leakage & transmitted radiation out of irradiation field. We attached OSLD with a 1cm away from the field at the side of phantom and applied a 3mm bolus equivalent to the thickness of eyelid. Results : Using human phantom, the Lens dose on IMRT treatment plan is 315.9cGy and the real measurement value is 216.7cGy. And after secondary shield using 3mm Pb plate and tungsten eye-shield block, each lens dose is 234.3, 224.1 cGy. The result of a experiment using acrylic phantom, each value is 5.24, 5.42 and 5.39 cGy in case of no block, 3mm Pb plate and tungsten eye-shield block. Applying O.S.B out of the field, each value is 1.79, 2.00 and 2.02 cGy in case of no block, 3mm Pb plate and tungsten eye-shield block. Conclusion : When secondary shielding material is used to protect critical organ while irradiating photon, high atomic number material (like metal) that is near by critical organ can be cause of dose increase according to treatment region and beam direction because head leakage and collimator & MLC transmitted radiation are exist even if it's out of the field. The attempt of secondary shield for the decrease of exposure dose was meaningful, but untested attempt can have a reverse effect. So, a preliminary inspection through Q.A must be necessary.

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Decision of GIS Optimum Grid on Applying Distributed Rainfall-Runoff Model with Radar Resolution (레이더 자료의 해상도를 고려한 분포형 강우-유출 모형의 GIS 자료 최적 격자의 결정)

  • Kim, Yon-Soo;Chang, Kwon-Hee;Kim, Byung-Sik;Kim, Hung-Soo
    • Journal of Wetlands Research
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    • v.13 no.1
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    • pp.105-116
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    • 2011
  • Changes in climate have largely increased concentrated heavy rainfall, which in turn is causing enormous damages to humans and properties. Therefore, the exact relationship and the spatial variability analysis of hydrometeorological elements and characteristic factors is critical elements to reduce the uncertainty in rainfall -runoff model. In this study, radar rainfall grid resolution and grid resolution depending on the topographic factor in rainfall - runoff models were how to respond. In this study, semi-distribution of rainfall-runoff model using the model ModClark of Inje, Gangwon Naerin watershed was used as Gwangdeok RADAR data. The completed ModClark model was calibrated for use DEM of cell size of 30m, 150m, 250m, 350m was chosen for the application, and runoff simulated by the RADAR rainfall data of 500m, 1km, 2km, 5km, 10km from 14 to 17 on July, 2006. According to the resolution of each grid, in order to compare simulation results, the runoff hydrograph has been made and the runoff has also been simulated. As a result, it was highly runoff simulation if the cell size is DEM 30m~150m, RADAR rainfall 500m~2km for peak flow and runoff volume. In the statistical analysis results, if every DEM cell size are 500m and if RADAR rainfall cell size is 30m, relevance of model was higher. Result of sensitivity assessment, high index DEM give effect to result of distributed model. Recently, rainfall -runoff analysis is used lumped model to distributed model. So, this study is expected to make use of the efficiently decision criteria for configurated models.

The Bone Regenerative Effects of Chitosan on the Calvarial Critical Size Defectin Sprague Dawley Rats (백서 두개골 결손부에서 키토산의 골조직 재생 유도 효과)

  • Jung, Ui-Won;Suh, Jong-Jin;Choi, Seong-Ho;Choi, Kyoo-Sung;Chai, Jung-Kiu;Kim, Chong-Kwan
    • Journal of Periodontal and Implant Science
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    • v.30 no.4
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    • pp.851-870
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    • 2000
  • The major goals of periodontal therapy is the functional regeneration of periodontal supporting structures already destructed by periodontal disease as well as the reduction of signs and symptoms of progressive periodontal disease. There have been many efforts to develop materials and therapeutic methods to promote periodontal wound healing. There have been increasing interest on the chitosan made by chitin. Chitin is second only to cellulose as the most abundant natural biopolymer. It is a structural component of the exoskeleton of invertebrates(e.g., shrimp, crabs, lobsters), of the cell wall of fungi, and of the cuticle of insects. Chitosan is a derivative of chitin made by deacetylation of side chains. Many experiments using chitosan in various animal models have proven its beneficial effects. The aim of this study is to evaluate the osteogenesis of chitosan on the calvarial critical size defect in Sprague Dawley rats. An 8 mm surgical defect was produced with a trephine bur in the area of the midsagittal suture. The rats were divided into two groups: Untreated control group versus experimental group with 50mg of soluble chitosan gel. The animals were sacrificed at 2, 4 and 8 weeks after surgical procedure. The specimens were examined by histologic, histomorphometric and radiodensitometric analyses. The results are as follows: 1. The length of newly formed bone in the defects was $102.91{\pm}25.46{\mu}m$, $219.46{\pm}97.81{\mu}m$ at the 2 weeks, $130.95{\pm}39.24{\mu}m$, $212.39{\pm}89.22{\mu}m$ at the 4 weeks, $181.53{\pm}76.35{\mu}m$ and $257.12{\pm}51.22{\mu}m$ at the 8 weeks in the control group and experimental group respectively. At all periods, the means of experimental group was greater than those of control group. But, there was no statistically significant difference between the two groups. 2. The area of newly formed bone in the defects was $2962.06{\pm}1284.48{\mu}m^2$, $5194.88{\pm}1247.88{\mu}m^2$ at the 2 weeks, $5103.25{\pm}1375.88{\mu}m^2$, $7751.43{\pm}2228.20{\mu}m^2$ at the 4 weeks and $8046.20{\pm}818.99{\mu}m^2$, $15578.57{\pm}5606.55{\mu}m^2$ at the 8 weeks in the control group and experimental group respectively. At all periods, the means of experimental group was greater than those of control group. The experimental group showed statistically significant difference to the control group at the 2 and 8 weeks. 3. The density of newly formed bone in the defects was $14.26{\pm}6.33%$, $27.91{\pm}6.65%$ at the 2 weeks, $20.06{\pm}9.07%$, $27.86{\pm}8.20%$ at the 4 weeks and $22.99{\pm}3.76%$, $32.17{\pm}6.38%$ at the 8 weeks in the control group and experimental group respectively. At all periods, the means of experimental group was greater than those of control group. The experimental group showed statistically significant difference to the control group at the 2 and 8 weeks. These results suggest that the use of chitosan on the calvarial defects in rats has significant effect on the regeneration of bone tissue in itself

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Removal of Nano-scaled Fluorescence Particles on Wafer by the Femtosecond Laser Shockwave (펨토초레이저 충격파에 의한 형광 나노입자 제거)

  • Park, Jung-Kyu;Cho, Sung-Hak;Kim, Jae-Gu;Chang, Won-Seok;Whang, Kyung-Hyun;Yoo, Byung-Heon;Kim, Kwang-Ryul
    • Journal of the Korean Society for Precision Engineering
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    • v.26 no.5
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    • pp.150-156
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    • 2009
  • The removal of tiny particles adhered to surfaces is one of the crucial prerequisite for a further increase in IC fabrication, large area displays and for the process in nanotechnology. Various cleaning techniques (wet chemical cleaning, scrubbing, pressurized jets and ultrasonic processes) currently used to clean critical surfaces are limited to removal of micrometer-sized particles. Therefore the removal of sub-micron sized particles from silicon wafers is of great interest. For this purpose various cleaning methods are currently under investigation. In this paper, we report on experiments on the cleaning effect of 100nm sized fluorescence particles on silicon wafer using the plasma shockwave occurred by femtosecond laser. The plasma shockwave is main effect of femtosecond laser cleaning to remove particles. The removal efficiency was dependent on the gap distance between laser focus and surface but in some case surface was damaged by excessive laser intensity. These experiments demonstrate the feasibility of femtosecond laser cleaning using 100nm size fluorescence particles on wafer.

Effects of Over-drive Pacing on the Suppression of Recurring the Atrial Fibrillation after open Heart Surgery (개심술후 오버드라이브 심방페이싱(Over-drive atrial pacing)의 심방세동발생억제에 대한 연구)

  • 박영환
    • Journal of Chest Surgery
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    • v.24 no.11
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    • pp.1081-1089
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    • 1991
  • Atrial fibrillation is characterized by beat to beat irregularity of shape, size, conduction time and polarity. The mechanism of atrial fibrillation can be explained by so called "Multiple wavelet theory". The adverse effect of atrial fibrillation is the decrease of cardiac output by absence of atrial kick[10 ~ 15%] and the possibility of thrombosis in the left atrium which is dangerous to develop the thromboembolism is increased. The present study was designed to assess the effect of overdrive pacing on the suppression of recurring of atrial fibrillation after open heart surgery and the results were summarized as follows: 1. There were no significant differences of factors between converting patients and non-converting patients to normal sinus rhythm by electric cardioversion after open heart surgery. 2. Among converting patients to normal sinus rhythm, there were no significant differences of factors between study group and control group. 3. Cardiothoracic Ratio on the preoperative chest film was significantly larger in the patients of recurring atrial fibrillation within 72hrs than in the patients of maintaining normal sinus rhythm. [61.7$\pm$ 1.4% vs 67.7$\pm$2.4%, p=0.03] 4. There was a significant difference of suppressive effects between overdrive pacing group and control group among recurred cases until 24, 48, and 72hours [Fisher`s exact test ; p=0.037, p=0.076, p=0.53, respectively] 5. There was a difference of the delay of recurring of atrial fibrillation between study group and control group among recurred cases within 72 hours.[53.4$\pm$6.9hr vs. 19.3$\pm$3.8 hr, p<0.01] We think that the overdrive pacing may suppress the natural pacemaker and the converted normal sinus rhythm is maintained longer than control group during critical immediate postoperative period.ve period.

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Temperature distribution in VX-2 hepatoma heated with thermoseed hyperthermia (열소자 온열요법시 VX-2 hepatoma내의 온도 변화에 대한 연구)

  • Choi, Ihl-Bohng;Bahk, Yong-Whee
    • Radiation Oncology Journal
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    • v.12 no.3
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    • pp.295-300
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    • 1994
  • It was the purpose of present study to develop a new thermoseed for heating deep-seated tumors and assessment of the effect of magnetic control on thermoseeds. Aqueous suspension of iron micro spheres (Ferropolysaccharide) was injected directly into the VX-2 hepatoma and heated with 1.2 MHz inductive radiofrequency unit. Aqueous thermoseed suspension was delivered to the tumor by simple percutaneous injection. The limitation of the thermoseed heating method is the positional change of thermoseed particles in the tumor after implantation. The thermoseed particles could enter the systemic blood circulation and cause a severe embolization of a critical organ. To minimize this limitation, we have used the magnetic control after loading the thermoseed in the tumor, W hen ferropolysaccharides were exposed to a strong magnetic field, they magnetized and subsequently exerted a magnetic force on each other, forming larger aggregates of particles. The size of aggregated Particles were too big to enter the systemic blood circulation. Thus, unlike other thermoseed method, we hold the thermoseed particles stationary in the tumor. The temperature of the injected site and immediate vicinity elevated by $4-5^{\circ}C$. The temperature of the surrounding normal hepatic tissue elevated by $1-2^{circ}C$ only. The heating effect within the tumor was variable depending on the density of ferromagnetic aqueous suspension. Our results suggest that inductive heating of tumor injected with ferropolysaccharide solution offers the possibility of effective heat delivery to the defined tumor volume, which is difficult to heat with other heating devices.

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Non-isothermal Crystallization Behavior of Poly(glycolide-co-ε-caprolactone-co-L-lactide) Block Copolymer (생체분해성 Poly(glycolide-co-ε-caprolactone-co-L-lactide) 블록 공중합물의 비등온 결정화 거동에 관한 연구)

  • Choi, Sei-Young;Song, Seung-Ho
    • Elastomers and Composites
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    • v.49 no.1
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    • pp.13-23
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    • 2014
  • In this work, glycolide, L-lactide and ${\varepsilon}$-caprolactone monomers were polymerized into the triblock copolymers by two step polymerization method and their non-isothermal crystallization behaviors were studied by combination of modified Avrami and Ozawa formula for further analysis of their behaviors. The result showed that PGCLA21 gave the highest value for supercooling analysis and super cooling degree increased with L-lactide content. Crystallization velocity constant, however, showed no significant change. The result of cooling function in specific relative crystallization degree showed that the increase of L-lactide content made an effect on the more enhancement of crystallization velocity of the PGCLA than PGCL. The result of big logF(T) value with the L-lactide content above critical point for PGCLA41 and PGCLA21 showed that bigger cooling velocity needed to gain same crystal size compared with PGCL. This means that it gives negative effect in the increase of crystallization velocity.

Numerical Analysis on Effects of Radius Ratio in a Concentric Annulus with a Rotating Inner Cylinder (내부회전실린더를 가진 동심환형관에서 반경비의 영향에 관한 수치해석적 연구)

  • Bae, Kang-Youl;Kim, Hyoung-Bum;Lee, Sang-Hyuk
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.327-330
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    • 2006
  • This paper represents the numerical analysis on effects of radius ratio in a concentric annulus with a rotating inner cylinder. The numerical model consisted of two cylinder which inner cylinder is rotating and outer cylinder is fix, and the axial direction is used the cyclic condition because of the length for axial direction is assumed infinite. The diameter of inner cylinder is assumed 86.8mm, the numerical parameters are angular velocity and radius ratio. Also, the whole walls of numerical model have no-slip and the working fluid is used water at $20^{\circ}C$. The numerical analysis is assumed the transient state to observe the flow variations by time and the 3-D cylindrical coordinate system. The calculation grid adopted a non-constant grid for dense arrangement near the wall side of cylinder, the standard $k-{\omega}$ high Reynolds number model to consider the effect of turbulence flow and wall, the fully implicit method for time term and the quick scheme for momentum equation. The numerical method is compared with the experimental results by Wereley and Lueptow, and the results are very good agreement. As the results, TVF isn't appeared when Re is small because of the initial flow instability is disappear by effect of the centrifugal force and viscosity. The vortex size is from 0.8 to 1.1 for TVF at various $\eta$, and the traveling distance for wavy vortex have the critical traveling distance for each case.

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Experiment on the Limit Scale of Combustion in Constant Volume Micro Combustor (초소형 정적 연소기에서의 연소 한계에 대한 실험적 연구)

  • 나한비;권세진;김세훈;이대훈
    • Journal of the Korean Society of Propulsion Engineers
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    • v.7 no.4
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    • pp.27-32
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    • 2003
  • The Performance of micro combustor in various condition was exploited experimentally. Various geometric conditions of combustor were considered to figure out the performance of micro combustor. The micro combustor studied in this study was constant volume with cylindrical shape. Geometric parameters of combustor were defined to be combustor height and diameter. The effect of height was exploited parametrically with the size of 1mm, 2mm and 3mm. The effect of diameter was observed parameterized with 7.5mm and 15mm. Three different combustibles or Stoichiometric mixture of methane/air, hydrogen/air were used. Pressure transition during combustion process was recorded. The maximum pressure by combustion responded favorably with the change of height of combustor and the initial pressure. The flame propagation was visulized using Schlieren method. The flame propagation within combustor was observed when specific conditions such as combustor height and initial pressure over critical value was satisfied.

Effect of Cu-contained solders on shear strength of BGA solder joints

  • Shin, Chang-Keun;Huh, Joo-Youl
    • Proceedings of the International Microelectronics And Packaging Society Conference
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    • 2000.04a
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    • pp.73-73
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    • 2000
  • Shear strength of BGA solder joints on Cu pad was studied for Cu-contained Sn n.5 a and 2.5wt.% Cu) and Sn-Pb (o.5wt.% Cu) solders, with emphasis on the roles of the C Cu-Sn intermetallic layer thickness and the roughness of the interface between the i intermetallic layer and solder. The shear strength test was performed both for a as-soldered s이der joints with soldering reaction times of 1, 2, 4 min and for aged s이der j joints at 170 C up to 16 days. The Cu addition to both pure Sn and eutectic Sn-Pb s solders increased the intermetallic layer thickness at both soldering and aging t temperatures. The Cu addition also resulted in changes in the roughness of the interface b between the intermetallic layer and solder at as-soldered states. With increasing Cu c content. the interface roughened for Sn-Cu solders whereas it flattened for Sn-Pb-Cu s solders. The shear fractures in all solder joints investigated were confined in the bulk s solder rather than through the intermetallic layer. Therefore, the effect of Cu content in s solders on the shear strength of the solder joints was primarily attributed to its i influence on the micros$\sigma$ucture of bulk solder, such as the size and spatial distributions of CU6Sn5 precipitates. In addition, the critical intermetallic layer thickness for a m maximum shear strength seemed to depend on the Cu content in bulk solder.older.

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