• Journal of the Korean Ceramic Society
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• v.41 no.4
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• pp.289-296
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• 2004

Whisker and short rod shaped hydroxyapatite (Ca$_{10}$(PO$_4$)$_{6}$(OH)$_2$ with stoichiometric composition (Ca/P=1.62 -1.67, molar ratio) has been synthesized by hydrolysis and hydrothermal reaction of aqueous $\alpha$-Ca$_3$(PO$_4$)$_2$($\alpha$-TCP) solution (pH 11), respectively. The shape of resultant HAp was mainly dependent on synthetic route and the microstructural development was on processing condition. In hydrolysis processing, the degree of intersection of whiskerlike particles and agglomeration in the apsis line increased with increasing reaction time. In hydrothermal synthesis, the reaction product obtained under excessive reaction time ($\geq$3 h at 20$0^{\circ}C$) was severely agglomerated without further grain growth above certain critical size (0.75 ${\mu}{\textrm}{m}$ in length, 0.3${\mu}{\textrm}{m}$ 11m in diameter).

• The korean journal of orthodontics
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• v.44 no.6
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• pp.294-303
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• 2014

Objective: The purpose of this study was to examine whether orthodontic treatment experience affects the individual's perception of smile esthetics and to evaluate differences among orthodontically treated laypersons, non-treated laypersons, and dentists by using computerized image alterations. Methods: A photograph of a woman's smile was digitally altered using a software image editing program. The alterations involved gingival margin height, crown width and length, incisal plane canting, and dental midline of the maxillary anterior teeth. Three groups of raters (orthodontically treated laypersons, non-treated laypersons, and dentists) evaluated the original and altered images using a visual analog scale. Results: The threshold for detecting changes in maxillary central incisor gingival margin height among laypersons was 1.5 mm; the threshold of dentists, who were more perceptive, was 1.0 mm. For maxillary lateral incisor crown width and height, the threshold of all three groups was 3.0 mm. Canting of the incisal plane was perceived when the canting was 3.0 mm among non-treated laypersons, 2.0 mm among treated laypersons, and 1.0 mm among dentists. Non-treated laypersons could not perceive dental midline shifts; however, treated laypersons and dentists perceived them when the shift was ${\geq}3.0mm$. Conclusions: Laypersons with and without orthodontic treatment experience and dentists have different perceptions of smile esthetics. Orthodontically treated laypersons were more critical than non-treated laypersons regarding incisal plane canting and dental midline shifts. Based on these findings, it is suggested that orthodontic treatment experience improved the esthetic perceptions of laypersons.

• Progress in Superconductivity and Cryogenics
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• v.19 no.2
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• pp.25-28
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• 2017

In superconducting coil applications particularly in wet wound coils, coated conductor (CC) tapes are subjected to different type of stresses that could affect its electromechanical transport property. These include hoop stress acting along the length of the CC tape and the Lorentz force acting perpendicular to the CC tape's surface. Since the latter is commonly associated with the delamination problem of multi-layered REBCO CC tapes, more understanding and attention on the delamination phenomena induced in the case of coil applications are needed. Difference on the coefficient of thermal expansion (CTE) of each constituent layer of the CC tape, the bobbin, and the impregnating materials is the main causes of delamination in CC tapes when subjected to thermal and mechanical cycling. In the design of degradation-free superconducting coils, therefore, characterization of the delamination behaviors including mechanism and strength in the multi-layered REBCO CC tapes becomes a critical issue. Various trials to increase the delamination strength by improving interface characteristics at interlayers have been performed. In this study, in order to investigate the influences of laser cleaning and Ag annealing treated at the substrate side surface, transverse tensile tests were conducted under different sample configurations using $4.5mm{\times}8mm$ upper anvil. The mechanical delamination strength of differently processed CC samples was examined at room temperature (RT). As a result, the Sample 1 with the additional laser cleaning and Ag annealing processes and the Sample 2 with additional Ag annealing process only showed higher mechanical delamination strength as compared to the Sample 3 without such additional treatments. Sample 3 showed quite different behavior when the loading direction is to the substrate side where the delamination strength much lower as compared to other cases.

• Journal of the Korean Ceramic Society
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• v.33 no.3
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• pp.339-347
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• 1996

Mechanical properties(flexural strength hardness fracture toughness) of alumina ceramics were evaluated. Alumina products of four companies were selected and three of those were made in Korea and one of those was made in Japan. The large differences according to manufacturing companies had resulted from flexural strength and weibull modulus which had a wide ranges of 300 to 400 MPa and 5 to 15 respectively. Critical indenstation load which could be neglected the effect of elastic recovery was about 9.8N and Vickers' hardness were about 15 GPa. Fracture toughnesses were evaluated by IF and ISB method. It was more preferable to the average at one indentation load that fracture toughness were obtained from the slope of the relationship between indentation load and crack length in IF method and between indentation load and fracture load in ISB method and fracture toughness was about 4 MPa·m1/2.

• Korean Journal of Clinical Pharmacy
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• v.27 no.3
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• pp.143-149
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• 2017

Background: L-asparaginase (L-ASP) is a critical agent for the treatment of acute lymphoblastic leukemia and lymphoma, which is associated with serious toxicities including hypersensitivity, pancreatitis and thrombosis. Methods: To evaluate the toxicity of L-ASP in real clinical settings, we included the patients with L-ASP adverse drug reactions (ADRs) reported in a regional pharmacovigilance center of Seoul St. Mary's hospital from January 2014 to December 2015. Results: A total of 83 cases of L-ASP related ADRs were reported in 54 patients. Of these 83 cases, 65 cases (78.3%, 65/83) were spontaneously reported and 18 cases (21.7%, 18/83) were detected by further medical records review. Of the patients with ADRs, pediatric patients accounted for 83.3% of the cases (45/54) and median age was 9 years. The most common clinical manifestations of ADRs were hematology manifestations (31.3%, 26/83), followed by hepatobiliary manifestations (18.1%, 15/83). Thirty-four serious ADRs were reported in 19 patients. The sserious ADR group showed significantly longer hospitalization and higher rate of discontinuation of L-ASP than the non-serious ADR group (p = 0.005, 0.03). The most common clinical manifestations of serious ADRs were hepatobiliary manifestations (41.2%, 14/34). In total, 8 cases (9.6%, 8/83) of unlabeled ADRs were identified. They were serious ADRs. Conclusion: We identified unlabeled serious ADRs of L-ASP. Also, correlations were observed between serious ADRs and length of hospitalization, discontinuation rate respectively. Further investigations and developed spontaneous ADR reporting systems are needed to evaluate these correlations.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.327-330
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• 2006

This paper represents the numerical analysis on effects of radius ratio in a concentric annulus with a rotating inner cylinder. The numerical model consisted of two cylinder which inner cylinder is rotating and outer cylinder is fix, and the axial direction is used the cyclic condition because of the length for axial direction is assumed infinite. The diameter of inner cylinder is assumed 86.8mm, the numerical parameters are angular velocity and radius ratio. Also, the whole walls of numerical model have no-slip and the working fluid is used water at $20^{\circ}C$. The numerical analysis is assumed the transient state to observe the flow variations by time and the 3-D cylindrical coordinate system. The calculation grid adopted a non-constant grid for dense arrangement near the wall side of cylinder, the standard $k-{\omega}$ high Reynolds number model to consider the effect of turbulence flow and wall, the fully implicit method for time term and the quick scheme for momentum equation. The numerical method is compared with the experimental results by Wereley and Lueptow, and the results are very good agreement. As the results, TVF isn't appeared when Re is small because of the initial flow instability is disappear by effect of the centrifugal force and viscosity. The vortex size is from 0.8 to 1.1 for TVF at various $\eta$, and the traveling distance for wavy vortex have the critical traveling distance for each case.

• Journal of Mechanical Science and Technology
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• v.15 no.7
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• pp.1041-1050
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• 2001

Control of bone cement volume (PMMA) may be critical for preventing complications in vertebroplasty, the percutaneous injection of PMMA into vertebra. The purpose of this study was to predict the optimal volume of PMMA injection based on CT images. For this, correlation between PMMA volume and textural features of CT images was examined before and after surgery to evaluate the appropriate PMMA amount. The gray level run length analysis was used to determine the textural features of the trabecular bone. Extimation of PMMA volume was done using 3D visualization with semi-automatic segmentation on postoperative CT images. Then, finite element (FE) models were constructed based on the CT image data of patients and PMMA volume. Appropriate material properties for the trabecular bone were assigned by converting BMD to elastic modulus. Structural reinforcement due to the changes in PMMA volume and BMD was assessed in terms of axial displacement of the superior endplate. A strong correlation was found between the injected PMMA volume and the area of the intertrabecular space and that of trabecular bone calculated from the CT images (r=0.90 and -0.90, respectively). FE results suggested that vertebroplasty could effectively reinforce the osteoporotic vertebra regardless of BMD or PMMA volume. Effectiveness of additional PMMA injection tended to decrease. For patients with BMD well lower than 50mg/ml, injection of up to 30% volume of the vertebral body is recommended. However, less than 30% is recommended otherwise to avoid any complications from excessive PMMA because the strength has already reached the normal level.

• The Journal of the Korea Contents Association
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• v.8 no.4
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• pp.273-284
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• 2008

Movements are a critical ability to young children's whole development, including physical, social/emotional, and cognitive development. This paper proposes the method to estimate movements suitable for young children's body conditions. The proposed method extracts a silhouette in each frame of videos that are obtained by deploying two video cameras by compensating illuminations, removing background and conducting morphology operations. And we extract silhouette feature values: an area, the ratio of length to width, the lowest foot position, and 7 Hu moments. Also, the area and movements of sub-area are used as local features. For motion estimation, we used probability propagation of the features extracted from the front and side frames. The proposed estimation algorithm is demonstrated for seven movements, walking, jumping, hopping, bending, stretching, balancing, and turning.

• Steel and Composite Structures
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• v.17 no.3
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• pp.215-236
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• 2014

The flexural behaviour of steel beams significantly affects the structural performance of the steel frame structures. In particular, the flexural overstrength (namely the ratio between the maximum bending moment and the plastic bending strength) that steel beams may experience is the key parameter affecting the seismic design of non-dissipative members in moment resisting frames. The aim of this study is to present a new formulation of flexural overstrength factor for steel beams by means of artificial neural network (NN). To achieve this purpose, a total of 141 experimental data samples from available literature have been collected in order to cover different cross-sectional typologies, namely I-H sections, rectangular and square hollow sections (RHS-SHS). Thus, two different data sets for I-H and RHS-SHS steel beams were formed. Nine critical prediction parameters were selected for the former while eight parameters were considered for the latter. These input variables used for the development of the prediction models are representative of the geometric properties of the sections, the mechanical properties of the material and the shear length of the steel beams. The prediction performance of the proposed NN model was also compared with the results obtained using an existing formulation derived from the gene expression modeling. The analysis of the results indicated that the proposed formulation provided a more reliable and accurate prediction capability of beam overstrength.

• Journal of the Society of Naval Architects of Korea
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• v.57 no.2
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• pp.80-87
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• 2020

As the Arctic sea ice decreases due to various reasons such as global warming, the demand for ships and offshore structures operating in the Arctic region is steadily increasing. In the case of sea ice, the anisotropy is caused by the uncertainty inside the material. For most of the research, nevertheless, estimating the ice load has been treated deterministically. With regard to this, in this paper, a four-point bending strength analysis of an ice specimen was attempted using a stochastic finite element method. First, spatial distribution of the material properties used in the yield criterion was assumed to be a multivariate Gaussian random field. After that, a direct method, which is a sort of stochastic finite element method, and a sensitivity method using the sensitivity of response for random variables were proposed for calculating the probabilistic distribution of ice specimen strength. A parametric study was conducted with different mean vectors and correlation lengths for each material property used in the above procedure. The calculation time was about ten seconds for the direct method and about three minutes for the sensitivity methods. As the cohesion and correlation length increased, the mean value of the critical load and the standard deviation increased. On the contrary, they decreased as the friction angle increased. Also, in all cases, the direct and sensitivity methods yielded very similar results.