• Proceedings of the KSME Conference
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• 2000.11a
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• pp.111-116
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• 2000

A semi-infinite interfacial crack propagated with constant velocity in two bonded anisotropic strip under out-of-plane clamped displacements is analyzed. The asymptotic stress and displacement fields near the crack tip are obtained, where the results get more general expressions applicable not only to isotropic/orthotropic materials but also to the extent of the anisotropic material having one plane of elastic symmetry for the interfacial crack. The dynamic stress intensity factor is obtained as a closed form, which is decreased as the velocity of crack propagation increases. The critical velocity where the stress intensity factor comes to zero is obtained, which agrees with the lower value between the critical values of parallel crack merged in the material 1 and 2 adjacent to the interface. The dynamic energy release rate is also obtained as a form related to the stress intensity factor.

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05a
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• pp.443-448
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• 1998

With using artificial neural networks (ANNs), an analytical study related to the heated length effect on critical heat flux(CHF) has been carried out to make an improvement of the CHF prediction accuracy based on local condition correlations or table. It has been carried out to suggest a feasible criterion of the threshold length-to-diameter (L/D) value in which heated length could affect CHF. And within the criterion, a L/D correction factor has been developed through conventional regression. In order to validate the developed L/D correction factor, CHF experiment for various heated lengths have been carried out under low and intermediate pressure conditions. The developed threshold L/D correlation provides a new feasible criterion of L/D threshold value. The developed correction factor gives a reasonable accuracy fur the original database, showing the error of -2.18% for average and 27.75% for RMS, and promising results for new experimental data.

• Structural Engineering and Mechanics
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• v.41 no.3
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• pp.339-348
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• 2012

The slope stability analysis is usually done using the methods of calculation to rupture. The problem lies in determining the critical failure surface and the corresponding factor of safety (FOS). To evaluate the slope stability by a method of limit equilibrium, there are linear and nonlinear methods. The linear methods are direct methods of calculation of FOS but nonlinear methods require an iterative process. The nonlinear simplified Bishop method's is popular because it can quickly calculate FOS for different slopes. This paper concerns the use of inverse analysis by genetic algorithm (GA) to find out the factor of safety for the slopes using the Bishop simplified method. The analysis is formulated to solve the nonlinear equilibrium equation and find the critical failure surface and the corresponding safety factor. The results obtained by this approach compared with those available in literature illustrate the effectiveness of this inverse method.

• Tuberculosis and Respiratory Diseases
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• v.87 no.1
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• pp.22-30
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• 2024

Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion. The tumor microenvironment contains various immune cells involved in immune evasion. Recent studies have demonstrated that granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) induce immune evasion in lung cancer by modulating neutrophils and myeloid-derived suppressor cells. Here we describe the origin and function of G-CSF and GM-CSF, particularly their role in immune evasion in lung cancer. In addition, their effects on programmed death-ligand 1 expression and clinical implications are discussed.

• Structural Engineering and Mechanics
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• v.46 no.1
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• pp.39-51
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• 2013

An extremum method is presented to predict the wrinkling characteristics of the inflated cone in bending. The wrinkling factor is firstly defined so as to obtain the wrinkling condition. The initial wrinkling location is then determined by searching the maximum of the wrinkling factor. The critical wrinkling load is finally obtained by determining the ratio of the wrinkling moment versus the initial wrinkling location. The extremum method is proposed based on the assumption of membrane material of beam wall, and it is extended to consider beam wall with thin-shell material in the end. The nondimensional analyses show that the initial wrinkling location is closely related to the taper ratio. When the taper ratio is higher than the critical value, the initial wrinkles will be initiated at a different location. The nondimensional critical wrinkling load nonlinearly increases as the taper ratio increases firstly, and then linearly increases after the critical taper ratio. The critical taper ratio reflects the highest load-carrying efficiency of the inflated cone in bending, and it can be regarded as a measure to optimize the geometry of the inflated cone. The comparative analysis shows fairly good agreement between analytical and numerical results. Over the whole range of the comparison, the mean differences are lower than 3%. This gives confidence to use extremum method for bending-wrinkling analysis of inflated conical cantilever beam.

• Journal of East-West Nursing Research
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• v.23 no.2
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• pp.124-133
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• 2017

Purpose: The purpose of this study was to identify factors that affect nursing students' clinical practice ability. Methods: The data were collected from 303 nursing students who had more than 500 hours of experience in clinical practicum at 4 universities in Seoul and the metropolitan area. The instruments consisted of 27 items of critical thinking, 19 items of professionalism, 40 items of self reported leadership, 20 items of communication evaluation tool, and 61 items of nursing practice performance evaluation. Results: For the clinical practicum, most difficult for nursing students were cardiopulmonary resuscitation, fecal enema, stoma care, and blood transfusion. Clinical practice abilities were positively correlated with nursing professionalism(r=.26, p<.001), leadership (r=.16, p=.007) and critical thinking(r=.12, p=.031). Professionalism(${\beta}=.32$, p=.001) was the most significant factor influencing the clinical practice ability of nursing students. Critical thinking was the second largest factor but not significant(${\beta}=.16$, p=.058). Conclusion: The findings suggest that the nursing curriculum should include nursing knowledge and nursing skills as well as various case-based or field-based decision making training programs to cultivate professionalism, critical thinking and other abilities for clinical practice.

• The Transactions of the Korean Institute of Power Electronics
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• v.18 no.1
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• pp.103-109
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• 2013

The conventional LCL filter design method of the utility interactive inverter considers only harmonics attenuation of the current injected to the grid. However, in case of utility-interactive inverter with critical load the voltage quality of the critical load should also be considered for LCL filter design. Also, considering cost and volume of LCL filters. it is important to have minimum values of inductance and capacitance as far as the harmonic standards are satisfied. In this paper a LCL filter design method is proposed to satisfy not only the harmonic standards of the grid current during the grid-connected mode but the voltage quality of the critical load during grid-connected mode and stand-alone mode. With the proposed method optimized values of LCL filters could be obtained by applying weighting factor to voltage ripple across the critical load, inductor volume, amount of reactive current and system bandwidth.

• Journal of the Korean Society of Propulsion Engineers
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• v.26 no.5
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• pp.24-34
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• 2022

In order to predict the cooling performance of a regenerative cooling channel using hydrocarbon fuel operating in the supercritical region, it is essential to predict the thermodynamic properties. In this study, a comparative analysis was performed on two-parameter equations of state (SRK(Soave-Redlich-Kwong), PR(Peng-Robinson) equations of state) and three-parameter equations of state (RK-PR equations of state) to appropriately predict density and specific heat according to the critical compressibility factor of polymer hydrocarbons. Representatively, n-dodecane fuel with low critical compressibility factor and JP-10 fuel with high critical compressibility factor were selected, and an appropriate equation of state was presented when predicting the thermodynamic properties of the two fuels. Finally, the prediction results of density and specific heat were compared and verified with NIST REFPROP data.

• Tuberculosis and Respiratory Diseases
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• v.73 no.4
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• pp.231-233
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• 2012

Tadalafil is a phosphodiesterase-5 inhibitor (PDE5I), which is widely used to treat erectile dysfunction. Although PDE5Is have excellent safety profiles, and most of the side effects are mild, rare serious adverse events have been reported in association with PDE5Is. Thrombosis is one of those events, and a few previous reports have suggested the association of PDE5Is with thrombosis. We report the case of a 61-year-old male who developed pulmonary embolism combined with pulmonary infarction directly after taking tadalafil. Both the patient and the physician suspected tadalafil as the culprit drug, as the patient was in an otherwise healthy condition. However, after extensive evaluation, we noticed that factor VIII levels were elevated. Prior reports suggesting the association between thrombosis and PDEIs either lack complete information on coagulation factors, or show inconsistencies in their results. Physicians should operate caution prior to accepting the diagnosis of adverse drug reaction.

• Structural Engineering and Mechanics
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• v.17 no.2
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• pp.167-186
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• 2004

The design load-carrying capacities of wooden shores depend on factors, such as the wood species and properties, and construction methods. This paper focuses on the construction methods, including an upright single shore, group of upright shores, group of inclined shores, butt connections and lap connections. This paper reports experiments to obtain critical loads and then developed an empirical equation based on Euler' formula for the critical loads and design load-carrying capacities. The test results show that the critical loads for an upright single wooden shore are greater than the average values for a group of upright shores, and the latter are greater than the average values for a group of inclined shores. Test results also show that the critical loads become smaller when butt or lap connections are used, butt connections possessing greater critical loads than lap connections. Groups of inclined shores are very popular at work sites because they have some practical advantages even though they actually possess inferior critical loads. This paper presents an improved setup for constructing groups of inclined shores. With this method, the inclined shores have larger critical loads than upright shores. The design load-carrying capacities were obtained by multiplying the average critical loads by a resistance factor (or strength reduction factor, ${\phi}$) that were all smaller than 1. This article preliminarily suggests ${\phi}$ factors based on the test results for the reference of engineers or specification committees.