• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.17 no.7
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• pp.754-759
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• 2004

We have studied the fringe field switching (FFS) mode with the positive dielectric anisotropy for the fast response time. The factors such as the physical properties of the LC, the cell gap, and the rubbing angle were critical for the fast response time of the FFS mode. The response time became 10 ms faster when the rotational viscosity of the new LC is 20 mPa.s lower than the conventional LC. When the cell gap changed from 3.6 ${\mu}{\textrm}{m}$ to 3.0 ${\mu}{\textrm}{m}$, it was possible to achieve the total response time and response times associated with grey-to-grey transitions under 16 ms. And the response times including grey-to-grey transitions become fast as the rubbing angle decreases.

• Wind and Structures
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• v.23 no.3
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• pp.191-209
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• 2016

Wind tunnel tests of a 1/2200-scale mountainous terrain model have been carried out to investigate local wind characteristics at a bridge location in southeast Tibet, China. Flows at five key locations on the bridge at deck level were measured for 26 directions. It was observed that wind characteristics (including mean wind velocity and overall turbulence intensity) vary significantly depending on the approaching wind direction and measurement position. The wind inclination angle measured in the study fluctuated between $-18^{\circ}$ and $+16^{\circ}$ and the ratio of mean wind velocity to reference wind velocity was small when the wind inclination angles were large, especially for positive wind inclination angles. The design standard wind speed and the minimum critical wind speed for flutter rely on the wind inclination angle and should be determined from the results of such tests. The variation of wind speed with wind inclination angles should be of the asymmetry step type. The turbulence characteristics of the wind were found to be similar to real atmospheric flows.

• Structural Engineering and Mechanics
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• v.84 no.5
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• pp.591-604
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• 2022

A gravity wall combined with an anchoring lattice frame (a combined retaining structure) is adopted at a typical engineering site at Dali-Ruili Railway Line China. Where, the combined retaining structure supports a soil deposit covering on different inclined rock slopes. With an aim to investigate and compare the effects of inclined rock slopes on the response of combined retaining structure under seismic excitation, three groups of shaking table tests are conducted. The rock slopes are shaped as planar surfaces inclined at angles of 20°, 30°, and 40° with the horizontal, respectively. The shaking table tests are supplemented by dynamic numerical simulations. The results regarding the horizontal acceleration response, vertical acceleration response, permanent displacement mode, and axial anchor force are comparatively examined. The acceleration response is more susceptible to outer structural profile of combined retaining structure than to inclined angle of rock slope. The permanent displacement decreases when the inclined angle of the rock slope increases within a range of 20°-40°. A critical inclined angle of rock slope exists within a range of 20°-40°, and induces the largest axial anchor force in the combined retaining structure.

• Genomics & Informatics
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• v.21 no.1
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• pp.6.1-6.8
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• 2023

Glaucoma is the second leading cause of irreversible blindness, and primary open-angle glaucoma (POAG) is the most common type. Due to inadequate diagnosis, treatment is often not administered until symptoms occur. Hence, approaches enabling earlier prediction or diagnosis of POAG are necessary. We aimed to identify novel drugs for glaucoma through bioinformatics and network analysis. Data from 36 samples, obtained from the trabecular meshwork of healthy individuals and patients with POAG, were acquired from a dataset. Next, differentially expressed genes (DEGs) were identified to construct a protein-protein interaction (PPI) network. In both stages, the genes were enriched by studying the critical biological processes and pathways related to POAG. Finally, a drug-gene network was constructed, and novel drugs for POAG treatment were proposed. Genes with p < 0.01 and |log fold change| > 0.3 (1,350 genes) were considered DEGs and utilized to construct a PPI network. Enrichment analysis yielded several key pathways that were upregulated or downregulated. For example, extracellular matrix organization, the immune system, neutrophil degranulation, and cytokine signaling were upregulated among immune pathways, while signal transduction, the immune system, extracellular matrix organization, and receptor tyrosine kinase signaling were downregulated. Finally, novel drugs including metformin hydrochloride, ixazomib citrate, and cisplatin warrant further analysis of their potential roles in POAG treatment. The candidate drugs identified in this computational analysis require in vitro and in vivo validation to confirm their effectiveness in POAG treatment. This may pave the way for understanding life-threatening disorders such as cancer.

• Steel and Composite Structures
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• v.19 no.1
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• pp.1-19
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• 2015

The buckling analysis is presented for non-homogeneous (NH) orthotropic truncated conical shells subjected to combined loading of axial compression and external pressure. The governing equations have been obtained for the non-homogeneous orthotropic truncated conical shell, the material properties of which vary continuously in the thickness direction. By applying Superposition and Galerkin methods to the governing equations, the expressions for critical loads (axial, lateral, hydrostatic and combined) of non-homogeneous orthotropic truncated conical shells with simply supported boundary conditions are obtained. The results are verified by comparing the obtained values with those in the existing literature. Finally, the effects of non-homogeneity, material orthotropy, cone semi-vertex angle and other geometrical parameters on the values of the critical combined load have been studied.

• Journal of Sensor Science and Technology
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• v.25 no.4
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• pp.243-246
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• 2016

The characteristics of a bimetallic surface plasmon resonance (SPR) chip were investigated to detect a tumor biomarker, carcinoembryonic antigen (CEA). The linewidth and the tangential slope of the reflectance curve of the bimetallic SPR chip was compared with those of the reflectance curve of a conventional gold (Au) SPR chip. The changes in reflectance in response to the variation in CEA in the critical concentration range were analyzed at an angle where the tangential slope of the reflectance curve was maximum. From linear regression analysis, the sensitivity of the bimetallic SPR chip with respect to the CEA in critical concentration was obtained.

• Journal of Welding and Joining
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• v.6 no.3
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• pp.37-42
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• 1988

The Hole Drilling Method(HDM) is widely used to measure residual stresses in the welded structures. The purpose of this study is to evaluate the accuracy fo measuring residual stresses when drilling the hole by Air-abrasive Jet machine(AJM). Simulated residual stresses wre introduced by applying known stresses to steel bars. These known streses were then compared with measured stresses relaxed from hole drilling. the obtained results are summarized as follows; 1) It was possible to obtain well defined holes with the nozzle designed for this study. 2) If the hole shape is not cylindrical, critical may occur. 3) In the uniaxial strain field, the measurement error of the maximum principal stress was within .+-.10 percent. The orientation angle of the maximum principal stress was within 8.deg. from the given directioin. 4) meausrements were made varying hole depths. Little or no change of stresses occurs since holse were drilled more than the depth of the 0.6 times diameter. 5) The air-abrasive jet machining for drilling holse does not cause appreciable apparent stresses which si critical to measure residual stresses.

• Journal of the Korea Institute of Military Science and Technology
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• v.4 no.1
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• pp.207-215
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• 2001

Plastic bonded explosive(PBX) is mainly composed of the nitramine-ploymer compositions. PBX is characterized by high velocity and pressure of detonation, low vulnerability and good thermal stability. Many important applications of PBX require the good adhesion between nitramine crystals and the binder. For PBXs as well as propellants, where good mechanical properties are of great importance, dewetting therefore must be prevented by strong adhesion between filler-binder. Adhesion depends on surface characteristics of filler and binder. In order to design for better adhesion, an understanding of the surface properties of explosive and binder is required. The surface free energies are calculated from contact angle values by the method of Kaelble. Critical surface tension of solids are calculated by Zisman plot. Critical surface tension is a useful parameter for characterizing the wettability of solid surface. In this study, HMX and 3 kinds of copolymers are selected, since they are widely used in many plastic bonded explosives. The technical objective of this investigation is to predict the interaction between filler and binder from their surface free energies.

• Journal of the Korean Society for Precision Engineering
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• v.14 no.3
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• pp.28-34
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• 1997

The side burrs and shape distortion resulting from the micromachining of an array of V-shape microgrooves in fresnel lens mould were experimentally invesigated. The focus of this study is on the influence of depth of cut and prism angle on the burr growing rate. The main experiments were con- ducted on the single prism cutting for the convinient of measuring the burr shape and cutting force. From the observation of the burr shape and burr growing rate, it was found that there exits a critical depth of cut below which the burrs are more or less irregular and weak. But above that critical value, the burrs are re- latively clear and stiff.

• Journal of Electrical Engineering and Technology
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• v.3 no.1
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• pp.29-35
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• 2008

With long time setting, zone 3 impedance relays are considered insensitive to power swings, and their operation condition during power swings is seldom analyzed. Instead of ti me-consuming simulation to the swing loci, their operation condition is directly quantified by polynominal functions in this paper to find the critical swing angle and frequency for relay operation under different relay settings and system parameters. It is found: (1) the swing loci are more densely populated inside than outside of the protection region, which corresponds to long residence time and possible relay operations; (2) the relays may be sensitive to load encroac hments and stable power swings with different relay settings and system parameters; (3) the critical swing frequency may be in the range of low-frequency power swings.