• The Korean journal of internal medicine
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• v.39 no.3
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• pp.477-487
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• 2024

Background/Aims: Risk factors for progression to critical illness in hospital-acquired coronavirus disease 2019 (COVID-19) remain unknown. Here, we assessed the incidence and risk factors for progression to critical illness and determined their effects on clinical outcomes in patients with hospital-acquired COVID-19. Methods: This retrospective cohort study analyzed patients admitted to the tertiary hospital between January 2020 and June 2022 with confirmed hospital-acquired COVID-19. The primary outcome was the progression to critical illness of hospital-acquired COVID-19. Patients were stratified into high-, intermediate-, or low-risk groups by the number of risk factors for progression to critical illness. Results: In total, 204 patients were included and 37 (18.1%) progressed to critical illness. In the multivariable logistic analysis, patients with preexisting respiratory disease (OR, 3.90; 95% CI, 1.04-15.18), preexisting cardiovascular disease (OR, 3.49; 95% CI, 1.11-11.27), immunocompromised status (OR, 3.18; 95% CI, 1.11-9.16), higher sequential organ failure assessment (SOFA) score (OR, 1.56; 95% CI, 1.28-1.96), and higher clinical frailty scale (OR, 2.49; 95% CI, 1.62-4.13) showed significantly increased risk of progression to critical illness. As the risk of the groups increased, patients were significantly more likely to progress to critical illness and had higher 28-day mortality. Conclusions: Among patients with hospital-acquired COVID-19, preexisting respiratory disease, preexisting cardiovascular disease, immunocompromised status, and higher clinical frailty scale and SOFA scores at baseline were risk factors for progression to critical illness. Patients with these risk factors must be prioritized and appropriately isolated or treated in a timely manner, especially in pandemic settings.

• Acute and Critical Care
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• v.33 no.4
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• pp.269-270
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• 2018

• Tuberculosis and Respiratory Diseases
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• v.65 no.3
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• pp.239-242
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• 2008

Exogenous lipoid pneumonia is an uncommon disease that's caused by aspirating lipid formulations. Squalene, obtained from shark liver oil, is one of the causative agent and this is commonly used by some Koreans as a health promoting medication. We report here on a case of exogenous lipoid pneumonia that developed after ingestion of squalene capsules. The case showed milky BAL fluid and multiple pulmonary consolidations.

• Journal of Veterinary Clinics
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• v.22 no.3
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• pp.198-201
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• 2005

The purpose of this study was to assess intra-individual variations of clinicochemical parameters and calculate critical differences in healthy dogs during long-term periods. To calculate the critical difference of clinicochemical parameters, blood samples from 20 apparently clinically healthy dogs were collected once weekly for eight consecutive weeks. The critical difference was calculated as 9.01 mg/dl for urea, 0.52 mg/dl for creatinine, 0.99 g/dl for total protein, 0.39 g/dl for albumin, and 20.64 mg/dl for glucose. If two consecutive results differ by less than the critical difference value, it can be concluded that the difference is probably due to physiological variation. However, when the difference is greater than the critical value, other factors, either related to progression of the disease or the presence of concurrent disease, are more likely to be involved.

• Journal of the Korean Geotechnical Society
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• v.19 no.1
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• pp.61-75
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• 2003

Comprehensive review on the determination of critical state parameters in sandy soils from standard triaxial testing was performed to facilitate the application of critical state soil mechanics to the shear behavior of sandy soils. First, semantic differences in literature were clarified, inferring that critical state should be considered as the ultimate state at large deformation. Second, the characteristics of critical state parameters were discussed, and also the uniqueness of critical state line and the sensitivity of quasi-steady state condition were verified in relation to initial state, fabric, loading condition, and drainage condition. Third, as an example, the critical state soil mechanics was applied to evaluate the post-liquefaction shear strength, i.e. the reliable ultimate shear strength in liquified soils, in terms of critical state parameters.

• The Mathematical Education
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• v.50 no.1
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• pp.69-87
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• 2011

The aim of this research is to develop a 'program which improves critical thinking' to improve elementary school students' mathematical thinking, and investigate the effect of program by applying and verifying the program. In order to achieve the objective, the author determined the factors of critical thinking capabilities matched to the discipline of mathematics, and accordingly designed relevant programs and test questions for critical thinking skills which contributes to improving the critical thinking of elementary school students, and thus applied the program the developed program of improving the critical thinking to both preliminary and main experiments, which verified the effects of the test method. The following results have been acquired through this research : In the preliminary inspection that this researcher has developed, it was able to predict that 'the program which improves critical thinking' would have a positive influence on the students' critical thinking. In the main experiment which was performed after modifying and supplementing it, the result showed that the program had a positive influence on the students' critical thinking.

• Earthquakes and Structures
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• v.18 no.1
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• pp.45-56
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• 2020

The application of critical excitation method with displacement-based objective function for multi degree of freedom (MDOF) systems is investigated. To this end, a new critical excitation method is developed to find the critical input motion of a MDOF system as a synthetic accelerogram. The upper bound of earthquake input energy per unit mass is considered as a new constraint for the problem, and its advantages are discussed. Considering this constraint, the critical excitation method is then used to generate synthetic accelerograms for MDOF models corresponding to three shear buildings of 10, 16, and 22 stories. In order to demonstrate the reliability of generated accelerograms to estimate dynamic response of the structures, three target ground motions with considerable level of energy contents are selected to represent "real critical excitation" of each model, and the method is used to re-generate these ground motions. Afterwards, linear dynamic analyses are conducted using these accelerograms along with the generated critical excitations, to investigate the key parameters of response including maximum displacement, maximum interstory drift, and maximum absolute acceleration of stories. The results show that the generated critical excitations can make an acceptable estimate of the structural behavior compared to the target ground motions. Therefore, the method can be reliably implemented to generate critical excitation of the structure when real one is not available.

• Women's Health Nursing
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• v.12 no.4
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• pp.316-325
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• 2006

Purpose: The purpose of this study was to develop a Critical Pathway for Uterine Artery Embolization patients. Method: There were 6 steps that were taken. Step 1 was selecting a diagnosis, and Step 2 was organizing a development team consisting of 7 experts. Step 3 analyzed the medical records, and Step 4 drew up a preliminary Critical Pathway. Step 5 tested the clinical validity of the preliminary Critical Pathway, and Step 6 developed the final Critical Pathway. Result: The contents of the medical practices observed in the medical records were investigated in seven areas: monitoring/assessment, treatment, medication, diet, activity, consults, and education/discharge plan; and a total of 73 items was identified. The validity of the 73 items was examined by a group of specialists. 68 items were adopted, 4 items revised, 1 item removed, and 1 item was added. Using the results, a preliminary Critical Pathway was drawn up. According to the results from examining the clinical validity of the preliminary Critical Pathway with five patients for five weeks, 3 items which showed discrepancy were revised and another 3 items were added. Then, the final Critical Pathway was completed. Conclusion: This Critical Pathway needs to be clinically applied and continuously to measure its effects in terms of the length of stay, cost.effectiveness, and the patients' and staffs' satisfaction.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.484-489
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• 2003

The mass flow rate of gas flow through critical nozzle depends on the nozzle supply conditions and the cross-sectional area at the nozzle throat. In order that the critical nozzle can be operated at a wide range of supply conditions, the nozzle throat diameter should be controlled to change the flow passage area. This can be achieved by means of a variable critical nozzle. In the present study, both experimental and computational works are performed to develop variable critical nozzle. A cone-cylinder with a diameter of d is inserted into conventional critical nozzle. It can move both upstream and downstream, thereby changing the cross-sectional area of the nozzle throat. Computational work using the axisymmetric, compressible Navier-Stokes equations is carried out to simulate the variable critical nozzle flow. An experiment is performed to measure the mass flow rate through variable critical nozzle. The present computational results are in close agreement with measured ones. The boundary layer displacement and momentum thickness are given as a function of Reynolds number. An empirical equation is obtained to predict the discharge coefficient of variable critical nozzle.

• Journal of Fisheries and Marine Sciences Education
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• v.19 no.2
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• pp.206-218
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• 2007

The purpose of this study was to investigate effects of critical thinking dispositions on vocational personalities in university students. Subjects were 111 University students in Busan. The questionnaire used in this research were Holland's Vocational Personality Questionnaire and California Critical Thinking Disposition Inventory. The results were analyzed by correlation analysis and enter multiple regression using the SPSS statistical package (SPSS for windows 12.0; SPSS Inc., Chicago, IL, USA). The study results were as follow: First, the students had much more S and R vocational personality characteristics than the others in vocational personality characteristics and had higher inquisitiveness and self-confidence scores than the others in critical thinking dispositions. Second, there were significant relationships between vocational personality types and critical thinking dispositions. Third, some of the vocational personality types were affected by the critical thinking dispositions. Especially I, E, and C personality of vocational personalities were prospected by critical thinking dispositions. Therefore, It's necessary that we understand the relationships between vocational personality types and critical thinking dispositions. Also we have to think over how to development career programs for university students to match to the learner's vocational personality type and critical thinking dispositions.