• 기술혁신연구
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• 제25권4호
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• pp.145-164
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• 2017

본 연구는 창조경제혁신센터의 향후 활용에 관한 논의를 목적으로 한다. 하지만 단순한 활용은 의미가 없다. 새로운 방식으로 탈바꿈 시킬 필요가 있다. 본 연구는 이에 관심을 가지면서 창조경제혁신센터형 생태계의 변화방향에 대한 단서를 얻는 것을 연구목적으로 하였다. 연구는 다음의 과정을 거쳤다. 첫째, 창조생태계 비교를 위한 기준을 이론적 고찰을 통해 도출하였다. 둘째, 도출된 기준을 중심으로 실리콘 밸리, 교토생태계 및 창조경제혁신센터형 생태계를 비교하였다. 셋째, 이런 분석을 통하여 창조경제혁신센터형 생태계 변화방향에 대한 논의를 하였다. 변화방향으로는 교토생태계가 적합할 것으로 제시되었다. 단, 정부의 역할은 직접적 통제에서 환경조성, 예로 지역 창조경제혁신센터형 생태계가 살아날 수 있도록 자극하는 규제완화와 시장형성을 돕는 것 등에 국한되어야 할 것으로 제시하였다.

• 한국미생물·생명공학회지
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• 제51권1호
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• pp.37-42
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• 2023

Neutral and non-essential amino acid, glutamine (Gln), plays an essential role in supplying nitrogen to all the amino acids and nucleotides in the mammalian body. Gln is also the most important carbon source that provides intermediates for gluconeogenesis and fatty acid synthesis and supplements the tricarboxylic acid cycle in fast-growing cancer cells. Among the known 14 Gln transporter genes, soluted carrier family 1 member 5 (SLC1A5) has been reported to be closely associated with cancer cell growth. Three variants (v1, v2, and v3) have been derived from SLC1A5. Here, we established a heterologous gene expression system for the active form of human SLC1A5 variant-2 (hSLC1A5v2) in Escherichia coli. v2 is the smallest variant that has not yet been studied. Four expression systems were investigated: pBAD, pCold, pET, and pQE. We also addressed the problem of codon usage bias. Although pCold and pET overexpressed hSLC1A5v2 in E. coli, they were functionally inactive. hSLC1A5v2 using the pBAD system was able to catalyze the successful transport of Gln, even if it was not highly expressed. Initial activity of hSLC1A5v2 for [¹⁴C] Gln uptake in E. coli reached up to 6.73 μmole·min^-1·gDW^-1 when the cell was induced with 80 mM L-arabinose. In this study, we demonstrated a heterologous expression system for the human membrane protein, SLC1A5, in E. coli. Our results can be used for the functional comparison of SLC1A5 variants (v1, v2, and v3) in future studies, to facilitae the developement of SLC1A5 inhibitors as effective anticancer drugs.

• 한국실내디자인학회논문집
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• 제22권2호
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• pp.120-130
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• 2013

Since Seoul city supplied 'Sangsang Children's Playground', domestic playgrounds are changing from formal facilities to creative play and learning space recently. From eco-friendly safe playground model development project, eco-friendly playground planning and its actual cases have been occasionally introduced. However, we could not know how well most playgrounds reflect eco-friendly features and whether they are eco-friendly or not because the definition about the concept of eco-friendly playground is inadequate and there are not the specific planning guidelines and evaluation standards for making the eco-friendly playground. Therefore, the development of guidelines for the construction of eco-friendly playground is required and evaluation guidelines for them should be made for the active dissemination of the actual eco-friendly playground and the proper construction of the eco-friendly playground. In this study, we defined the concept of eco-friendly outdoor playground and presented the types and characteristics of the playground based on the concept and suggested basic plan guidelines based on the existing requirements for becoming eco-friendly playground. For this purpose, we checked the plan's common points in the existing playground configuration requirements, installation standards, regulations, and safety standards, and offered the planning elements and guidelines through the analysis of outdoor space evaluation standard in eco-friendly safe playground guidelines and eco-friendly building certification system.

• 한국실내디자인학회논문집
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• 제20권6호
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• pp.19-26
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• 2011

The purpose of this study was to small house plans according to the preferred type of emotional design. The human emotions was a major factor for small houses plan's needs. In this study is direction of the basic plan for the small houses of the spatial planning and services and the needs of community facilities. Preferred types of emotional design was identify the propensity of consume, adjectives, colors and forms. For this study, survey methods were used for data collection. The effective numbers of survey questionnaire was 183, and the survey analysis has been made by using of SPSS win 18.0. The major findings were as followings: 1) Preferred types of emotional design were "Eco-Classic oriented group", "Unspecified commonness group", "Creative design oriented group" classified. 2) "Eco-Classic oriented group" wanted Eco-system and the community space. "Unspecified commonness group" wanted Simple and universal style. "Creative design oriented group" wanted flexible styles and various items. Therefore, depending on need group is the main target-specific as well as flat planning and interior style facilities and the provision of services to be competitive in the small house could indicate. These results can provide improvement guidelines for the small house plans.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 추계학술대회 논문집
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• pp.1757-1764
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• 2004

It is the urgent task of induce the inhabitants to utilize the public transportation instead of the personal transportation to dissolve the traffic jam. But construction of the subway, the representative substitute means, demands a great of investment expense including various kinds of expenses. So the technical development and research of standardization of FRT(Fuel cell Rubber tired Train), the eco-friendly public transportation system low in construction expenses, effective, excellent in approach as well as in traffic, are propelled positively. This project wants to propose exterior design FRT in which original creative methods are utilized with the target of development and construction of FRT which coincide with anthropocentric eco-friendly traffic system. Utilizing the proposed style as the basic materials, this project wants to grasp difficulties, and to establish the way to solve and develop them.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2018년도 추계학술발표대회
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• pp.339-342
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• 2018

The resent work is about the design and installation of the 60 URT heat pump according to the need. This design is eco-friendly, easily available, reduces maintenance and electricity cost. The dimensions of heat pump is $1500mm{\times}500mm{\times}1940mm$ (i.e length 1500 mm, width 500 mm and height 1940 mm) is installed on site. It can be operated with automation (PID) and controlled by sensors. The performance of and heat pump is evaluated experimentally by the monitoring system.

• 한국의류산업학회지
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• 제19권3호
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• pp.259-266
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• 2017

In a contemporary fashion along with the advance of high technology, development of a new material is being increasingly emphasized and the need of creative convergence using a computer is being expanded. As a global designer who appeared through association between Japan and the West, Issey Miyake has been continually pursuing a new challenge and a solution using high technology, leading the globalization of Japanese fashion. This research aims at examining design characteristics of Issey Miyake collection's A-POC showing a new paradigm, that is, an innovative clothing manufacture system to input information on materials, colors and shapes into a textile machine based on the computer program and manufacture a cylindrical fabric for completion of seamless clothing without sewing or cutting. A-POC is evolving continually through the development of new materials including recycled fibers and organics together with diversification of processing technology. Besides, it shows design characteristics including an integrated manufacturing method, autonomy for customers' selection, practicality for comfortable wearing by the majority, environment friendly idea to reduce waste of fabrics and materials and a new presentation through convergence of exhibition concepts of modern art. This research on Issey Miyake's A-POC characteristics is expected to present a role of fashion designers in a new design idea and paradigm of contemporary clothing using high technology.

• 유통과학연구
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• 제14권9호
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• pp.31-45
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• 2016

Purpose - This study develops a simulation model that looks at the dynamics between social capital and business performance in strategic networks to understand their behaviors in relation to each other, and to suggest dynamic relationship strategies. Research design, data, and methodology - Based on existing literature, this study identifies the complex causal loop diagram on social capital and business performance in strategic networks, and converts them into a simulation model for observing how the changes in business environment and relationship dependency affect social capital and business performance. Results - The simulation results showed that, first, the formation in social capital and business performance of networks with low relationship dependency was less affected by the changes in business environment. Second, the formation in social capital and business performance of networks with high relationship dependency was negatively impacted by the changes in business environment. In other words, higher relationship dependency strengthened the impact of changes in business environment on business performance. Conclusions - Thus, this study confirmed that in strategic networks, the changes in business environment and the degree of relationship dependency dynamically affect business performance, and that relationship dependency mediates the degree in which changes in the business environment affect business performance. The results of the simulations were further verified through actual business cases.

• 한국정보통신학회논문지
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• 제20권5호
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• pp.963-971
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• 2016

본 논문은 윈도윙 시스템 GUI에서의 다중 창 전환 이용행위 측정을 위한 시선분석 시스템 및 방법 개발을 연구한 것이다. 기존의 시선 분류를 위한 관심 영역 지정 방식은 시간에 따라 나타났다가 사라지거나 변화하는 다이내믹 콘텐트를 지정하기에 어려움이 컸다. 그러나 본 연구는 창 단위로 이루어지는 작업 전환 행위를 측정하기 위해 개별 창의 관심영역 WOI(Window of Interest)를 실험 진행과 동시에 실시간으로 지정하여 시선을 분류하고 이에 따른 창 전환 회수 및 주시 콘텐트의 비율 등을 분석하는 연구 방법을 제시하였다. 본 연구에서 제시한 분석 시스템은 다중 창 이용이라는 멀티태스킹을 측정하고 분석할 수 있다는 점에서 기존 연구방법과는 매우 다른 접근이다.

• 한국시스템다이내믹스연구
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• 제15권4호
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• pp.5-28
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• 2014

국제통상을 하는 기업은 위험 선호도에 따라 금융시장을 통해 외화자산 혹은 외화부채의 헷징(hedging)을 목적으로 파생금융상품을 쉽게 구매할 수 있다. 파생금융상품 시장은 투자와 헷지의 필요에 따라 급속도로 성장해왔다. 기업은 금융 파생금융상품을 통해 환위험 관리를 하면서 위험을 헷징한다. 기초자산을 헷징할 때는 환노출 완화전략으로 헷징이 효과적일 수 있다. 하지만 파생상품을 통한 이익에 대한 욕심과 예상치 못한 환율 변동이 발생할 때 기업에 상당한 위험을 초래할 수도 있다. 본 논문은 환위험을 다루는 파생상품에 내재된 구조적인 위험을 시스템다이내믹스 관점에서 분석하고 있다. 대표적인 파생금융상품인 KIKO는 구조적인 위험 요인 때문에 금융위기에 크나 큰 손실을 끼쳤다. 본 논문에서는 KIKO의 구조적 위험 요인을 모델링하고 실제 사례를 통해 검증하여 파생금융상품의 시스템 구조를 파악하고 내재되어 있는 구조적 위험을 밝혔다.