• Journal of Microbiology and Biotechnology
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• v.29 no.1
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• pp.21-29
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• 2019

The effects of Lavandula angustifolia extract fermented with Pediococcus pentosaceus DK1 on UVB-mediated MMP-1 expression and collagen decrease in human skin fibroblasts were determined, and the conversion of its components was also analyzed. Fermentation was performed at varying L. angustifolia extract and MRS medium concentrations, and optimal fermentation conditions were selected. L. angustifolia extracts showed decreased cytotoxicity after fermentation in the fibroblasts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extract showed MMP-1 expression 8.2-14.0% lower than that in UVB-irradiated fibroblasts treated with non-fermented extract. This was observed even at fermented extract concentrations lower than those of non-fermented extracts. Fibroblasts treated with fermented L. angustifolia extract showed 20% less reduction in collagen production upon UVB irradiation than those treated with non-fermented extracts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extracts showed 50% higher inhibition of ROS generation than those treated with non-fermented extract. Luteolin and apigenin glycosides of L. angustifolia were converted during fermentation, and identified using RP-HPLC and LC/ESI-MS. Therefore, the effects of L. angustifolia extract on MMP-1 expression and collagen decrease in UVB-irradiated human skin fibroblasts were increased through fermentation by P. pentosaceus.

• Journal of Electrical Engineering and Technology
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• v.13 no.6
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• pp.2441-2446
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• 2018

This paper presents a radio frequency-to-direct current (RF-to-DC) converter for special RF power harvesting application at 915 MHz. The major featured components of the proposed RF-to-DC converter is the combination of a cross-coupled rectifier and an active diode: first, the cross-coupled rectifier boosts the input voltage to desired level, and an active diode blocks the reverse current, respectively. A prototype was implemented using $0.18{\mu}m$ CMOS technology, and the performance was proven from the fact that the targeted RF harvesting system's full-operation with higher power efficiency; even if the system's input power gets lower (e.g., from nominal 0 to min. -12 dBm), the proposed RF-to-DC converter constantly provides 1.47 V, which is exactly the voltage level to drive follow up system components like DC-to-DC converter and so on. And, maximum power conversion efficiency is 82 % calculated from the 0 dBm input power, 2.3 mA load current.

• International Journal of Aeronautical and Space Sciences
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• v.15 no.1
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• pp.44-53
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• 2014

A lightning strike to the aircraft seriously affects the aircraft and its components in various ways. As one of the most critical threats to the flight safety of an aircraft, fuel vapour ignition by lightning can occur through various means, notably through hot spot formation on the fuel tank skins. In this study, a coupled thermal-electrical approach using the commercial software ABAQUS is used to study the effects of a lightning strike on aircraft fuel tanks. This approach assumes that the electrical conductivity of a material depends on temperature, and that a temperature rise in a material due to Joule heat generation depends on electrical current. The inter-dependence of thermal and electrical properties-the thermal-electrical coupling-is analyzed by a coupled thermal-electrical analysis module. The analysis elucidates the effects of different material properties and thicknesses of tank skins and identifies the worst case of lightning zones.

• Journal of Microbiology and Biotechnology
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• v.22 no.7
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• pp.939-946
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• 2012

Antibiotic production with Streptomyces sindenensis MTCC 8122 was optimized under submerged fermentation conditions by artificial neural network (ANN) coupled with genetic algorithm (GA) and Nelder-Mead downhill simplex (NMDS). Feed forward back-propagation ANN was trained to establish the mathematical relationship among the medium components and length of incubation period for achieving maximum antibiotic yield. The optimization strategy involved growing the culture with varying concentrations of various medium components for different incubation periods. Under non-optimized condition, antibiotic production was found to be $95{\mu}g/ml$, which nearly doubled ($176{\mu}g/ml$) with the ANN-GA optimization. ANN-NMDS optimization was found to be more efficacious, and maximum antibiotic production ($197{\mu}g/ml$) was obtained by cultivating the cells with (g/l) fructose 2.7602, $MgSO_4$ 1.2369, $(NH_4)_2PO_4$ 0.2742, DL-threonine 3.069%, and soyabean meal 1.952%, for 9.8531 days of incubation, which was roughly 12% higher than the yield obtained by ANN coupled with GA under the same conditions.

• Computers and Concrete
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• v.20 no.3
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• pp.257-262
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• 2017

This study aims to develop a signal processing scheme to accurately predict the thickness of concrete slab using air-coupled impact-echo. Air-coupled impact-echo has been applied to concrete non-destructive tests (NDT); however, it is often difficult to obtain thickness mode frequency due to noise components. Furthermore, apparent velocity in concrete is a usually unknown parameter in the field and the thickness of the concrete slab often cannot be accurately measured. This study proposes a signal processing scheme using guided wave analysis, wherein dispersion curves are drawn in both frequency-wave number (f-k) and phase velocity-frequency ($V_{cp}-f$) domains. The theoretical and experimental results demonstrate that thickness mode frequency and apparent velocity in concrete are clearly obtained from the f-k and $V_{cp}-f$ domains, respectively. The proposed method has great potential with regard to the application of air-coupled impact-echo in the field.

• Archives of Pharmacal Research
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• v.21 no.2
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• pp.212-216
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• 1998

A coupled achiral-chiral high-performance liquid chromatographic system has been developed for the determination of the enantiomers of salmeterol, S-(+)-salmeterol and R-(-)-salmeterol in urine. THe salmeterol was separated from the interfering components in urine and quantified on the silica column, and the enantiomeric composition was determined on a Sumichiral OA-4700 chiral stationary phase. The two columns were connected by a switching valve equipped with a silica precolumn. The two columns wer connected by a switching valve equipped with a silica precolumn. The precolumn was used to concentrate the salmeterol in the eluent from the achiral column before backflushing onto the chiral phase. The coupled system was validated.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.2
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• pp.109-117
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• 2004

Optimization has been successfully applied to systems with a single discipline. As many disciplines are involved in coupled fashion, MDO (multidisciplinary design optimization) technology has been developed. MDO algorithms are trying to solve the coupled aspects generated from interdisciplinary relationship. In a general MDO algorithms, a large design problem is decomposed into small ones which can be easily solved. Although various methods have been proposed for MDO, the research is still in the early stage. This research proposes a new MDO method which is named as MDOIS (Multidisciplinary Design Optimization Based on Independent Subspaces). Many real engineering problems consist of physically separate components and they can be independently designed. The inter-relationship occurs through coupled physics. MDOIS is developed for such problems. In MDOIS, a large system is decomposed into small subsystems. The coupled aspects are solved via system analysis which solves the coupled physics. The algorithm is mathematically validated by showing that the solution satisfies the Karush-Kuhn-Tucker condition.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.11 no.6
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• pp.181-192
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• 2001

The power flow analysis (PFA) has been performed to analyze the vibration of coupled plates excited by a point force in an arbitrary direction. The point force generates the out-of-plane vibration associated wish flexural waves and the in-plane vibration associated with longitudinal and shear waves. The energy governing equation for each type of waves was introduced and solved to Predict the vibrational energy density and intensity generated by the out-of-plane and in-plane components of the point force in an arbitrary direction. The wave transmission approach was used to consider the mode conversion at the joint of the coupled plates. Numerical results for vibrational energy density and intensity on the coupled plates were presented. Comparison of the results by PFA with exact results showed that PFA can be an effective tool to predict the spatial variation of the vibrational energy and intensity on the coupled plates at high frequencies.

• Korean Journal of Optics and Photonics
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• v.12 no.6
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• pp.437-445
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• 2001

We examine theoretically the properties of the force on Mie particles induced by evanescent fields at a system of multilayer films (including a metal film), at which the surface plasmon resonance is excited by a p-polarized plane electromagnetic wave. An expression of the surface plasmon-coupled evanescent fields produced in Kretschmann (or Sarid) geometry is expanded in terms of vector spherical wave functions, while multiple reflections between the Mie particle and the metal boundary are taken into account. The Cartesian components of the force on Mie particles by the evanescent fields are analytically formulated and numerically evaluated. The force components are increased by one or two orders of magnitude at metal boundaries over those at dielectric boundaries. As a result, we can confirm the possibility of stable manipulation or rotation of a finite-sized object by forces of surface plasmon-coupled evanescent fields.

• Proceedings of the KIEE Conference
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• 2002.07c
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• pp.1760-1762
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• 2002

In this work we develop an equivalent circuit model of TCP(transformer coupled plasma) source and investigate matching characteristic. The developed circuit model includes transmission line, standard-type impedance matching network and displacement current in the plasma source. The impedance of TCP is calculated by previously developed program for various source parameters and dependance of components of matching impedance on the value of source impedance is investigated.