• Title/Summary/Keyword: Counter current flow

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Isolation and Purification of Bioactive Materials Using High-Performance Counter-Current Chromatography (HPCCC) (고속역류크로마토그래피 기술을 이용한 생리활성 물질의 분리 및 정제)

  • Jung, Dong-Su;Shin, Hyun-Jae
    • KSBB Journal
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    • v.25 no.3
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    • pp.205-214
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    • 2010
  • Many successive liquid-liquid extractions occur enabling purification of the crude material to occur. In high performance counter-current chromatography (HPCCC), crude material is partitioned between two immiscible layers of solvent phases. The stationary phase (SP) is retained by hydrodynamic force field effect and the mobile phase (MP) is pumped through the column. Purification occurs because of the different solubility of the components in the liquid mobile and stationary phases. There are many key benefits of liquid stationary phases such as high mass and volume injection loadings, total sample recovery, and easy scale-up. Many researchers showed that predictable scale-up from simple test is feasible with knowledge of the stationary phase retention for the planned process scale run. In this review we review the recent advances in HPCCC research and also describe the key applications such as natural products and synthetics (small or large molecules).

A Numerical Model for Heat and Mass Transfer Processes within a Vertical Tube GAX Absorber (수직원관형 GAX 흡수기 내부의 열 및 물질전달과정에 대한 수치모델)

  • 천태식;정은수
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.12 no.1
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    • pp.102-111
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    • 2000
  • A numerical model which simulates the simultaneous heat and mass transfer within a vertical tube GAX absorber was developed. The ammonia vapor and the solution liquid are in counter-current flow, and the hydronic fluid flows counter to the solution liquid. The film thickness and the velocity distribution of the liquid film were obtained by matching the shear stress at the liquid-vapor interface. Two-dimensional diffusion and energy equations were solved in the liquid film to give the temperature and concentration, and a modified Colburn-Drew analysis was used for the vapor phase to determine the heat and mass fluxes at the liquid-vapor interface. The model was applied to a GAX absorber to investigate the absorption rates, temperature and concentration profiles, and mass flow rates of liquid and vapor phases. It was shown that the mass flux of water was negligible compared with that of ammonia except the region near the liquid inlet. Ammonia absorption rate increases rapidly near the liquid inlet and decrease slowly. Both the absorption rate of ammonia vapor and the desorption rate of water near the liquid inlet increase as the vapor mass flow rate increases, but the mass fluxes of the ammonia and the water near the liquid outlet decrease as the mass flow rate of the vapor increases.

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Performance Characteristics of PEMFC by flow Configurations and Operating Condition (유로형상 및 운전조건에 따른 고분자 전해질 연료전지의 성능 특성)

  • Lee, Pil-Hyong;Cho, Son-Ah;Han, Sang-Seok;Hwang, Sang-Soon
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.3440-3445
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    • 2007
  • For proton exchange membrane fuel cell, it is very important to design the flow channel on separation plate optimally to maximize the current density at same electrochemical reaction surface and reduce the concentration polarization occurred at high current density. In this paper, three dimensional computation model including anode and cathode domain together was developed to examine effects of flow patterns and operation conditions such as humidity and operating temperature on performance of fuel cell. Results show that voltage at counter flow condition is higher than that at coflow condition in parallel and interdigitated flow pattern. And fuel cell with interdigitated flow pattern which has better mass transport by convection flow through gas diffusion layer has higher performance than with parallel flow pattern but its pressure drop is increased such that the trade off between performance and pressure drop should be considered for selection of flow pattern of fuel cell.

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Study on the Effects of the Flow Characteristics and Size on the Peformance of Molten Carbonate Fuel Cells Using CFD (CFD를 통한 용융탄산염 연료전지의 유동 및 크기에 따른 운전 특성 분석)

  • KIM, DONG-WOO;KIM, HA-YOUNG;CHOI, JEONG-HWAN;LEE, CHANG-WHAN
    • Transactions of the Korean hydrogen and new energy society
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    • v.30 no.2
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    • pp.147-154
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    • 2019
  • In this study, effects of flow types and size of molten carbonate fuel cells (MCFCs) were investigated using CFD simulation. In the simulation, the current collector of MCFCs were assumed to be an porous media. With the area of $0.09m^2$, the effect of flow types such as Co-flow, Counter-flow, Cross-flow were studied. After that the effect of the size and flow direction was studied. Among three-flow types, MCFCs with co-flow type shows more uniform distribution and current density distribution.

Friction in Micro-Channel Flows of a Liquid and Vapor in Trapezoidal Grooves (미소 사다리꼴 그루브를 갖는 채널내의 유동에서 기-액의 상호마찰의 영향)

  • Suh, Jeong-Se;Grief, Ralph
    • Proceedings of the KSME Conference
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    • 2000.11b
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    • pp.124-129
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    • 2000
  • The flow of liquid and vapor is investigated in trapezoidal grooves. The effect of variable shear stress along the interface of the liquid and vapor is studied for both co-current and counter-current flows. Velocity contours and results fur the friction are obtained for both trapezoidal grooves. An approximate relation that was previously utilized for the friction for the liquid was modified to obtain accurate agreement with the results for trapezoidal grooves.

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Heat and Mass Transfer Analysis of Phosphoric Acid Fuel Cell According to Variation of gas Flow passage (인산형 연료전지의 가스유로방향 변화에 따른 열 및 물질전달해석)

  • 전동협;정영식;채재우
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.18 no.5
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    • pp.1338-1346
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    • 1994
  • The objective of this study is to investigate the effect of various parameters, such as temperature, mean current density and voltage on the performance of phosphoric acid fuel cell (PAFC) by numerical analysis. Two types of flow passages, which are Z-parallel type and Z-counter type, are evaluated to obtain the best current density and temperature distribution. Parametric studies and sensitivity analysis of the PAFC system's operation in single cell are accomplished. A steady state simulation of the entire system is developed using nonlinear ordinary differential equations. The finite difference method and trial and error procedures are used to obtain a solution.

A NUMERICAL STUDY ON HEAT TRANSFER ENHANCEMENT BY PULSATILE FLOW IN A PLATE HEAT EXCHANGER (판형 열교환기의 맥동유동에 의한 열전달 향상에 관한 수치해석연구)

  • Lee, Myung-Sung;Hur, Nahm-Keon;Kang, Byung-Ha
    • 한국전산유체공학회:학술대회논문집
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    • 2006.10a
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    • pp.93-96
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    • 2006
  • The heat transfer enhancement by pulsatile flow in the plate heat exchanger has been investigated numerically in the present study. The numerical study was performed in the range of the mass flux from 0.04 to 0.12 kg/s. The results showed that the pulsatile flow produces resonating vortex shedding at the groove sharp edges and a strong transient vortex rotation within the grooved channels. As a result, the mixing between the trapped volume in the grooved cavity and the main stream was enhanced. Good agreements between the predictions and measured data are obtained in steady flow. And the heat transfer of pulsatile flow is about 2.4 times than steady flow when frequency is 10 Hz and the mass flux of cold side is 0.04 kg/s.

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Numerical Prediction of Forced Convective Boiling Heat Transfer and Flow in Steam Generator Helical Coils (헬리컬 증기발생기 코일에서 강제대류 비등 열전달 및 유동의 수치 적 예측)

  • Jo J. C.;Kim H. J.;Kim W. S.;Yu S. O.
    • 한국전산유체공학회:학술대회논문집
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    • 2004.10a
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    • pp.127-130
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    • 2004
  • In this study, three-dimensional numerical calculations are peformed to simulate the flow and heat transfer in helically coiled tube steam generator employing a commercial CFD (Computational Fluid Dynamics) code. The problem considered herein includes the boiling phase change flow of tube side fluid and the single-phase counter-current flow of shell side hot fluid transferring heat to the tube side flow thru the tube wall. Detailed investigations are performed for both shell-side and tube-side flow fields in terms of density and volume fractions of each phase of fluids as well as for the tube wall heat transfer field in terms of heat transfer coefficients.

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Convergence of Fluid Dynamics and Computer Simulation for the Internal Investigation of Fuel Cell (유체역학과 컴퓨터 시뮬레이션의 융합을 통한 연료전지의 분석)

  • Kim, Se Hyun
    • Journal of Digital Convergence
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    • v.14 no.6
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    • pp.245-251
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    • 2016
  • A numerical model is developed to predict distributions of current density and temperature. Also the complete fuel cell performances were compared. In this study the effect of flow field design and flow direction on current density and temperature distribution as well as full cell performance. The complete three-dimensional Navier-Stokes equations were solved with convergence of electro-chemical reactions terms. In this paper, the two different flow field design were simulated, straight channel and rectangular serpentine flow channel, which is commonly used. The effect of flow direction, co-flow and counter-flow, was also analyzed. The current density and temperature is higher with abundant oxygen not fuel. Also, temperature distribution was able to be drawn by using computer simulation. In this paper, the relationship among flow pattern, flow field design and current denstity distribution.