• Journal of Plant Biotechnology
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• 제43권4호
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• pp.432-437
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• 2016

Interleukin-11 (IL-11) is a cytokine that plays a key regulatory role in the immune system. Recombinant human IL-11 (rhIL-11) exerts a preventative effect against apoptotic cell death and inhibits preadipocyte differentiation. IL-11 also is used to stimulate the bone marrow to produce platelets in order to prevent low platelets that may be caused by chemotherapy. Unfortunately, the high production cost of IL-11 associated. In this study, we investigated the feasibility of transgenic plants for the cost-effective production of rhIL-11. Production of rhIL-11 proteins in whole-plant expression system will be more economical when compared to the current E. coli based expression system. The human rhIL-11 gene was codon optimized to maximize plant host system expression. IL-11 expression vector under the control of a constitutive cauliflower mosaic virus 35S (CaMV 35S) promoter was introduced into tobacco by Agrobacterium-mediated transformation. The 5'-leader sequence (called ${\Omega}$) of tobacco mosaic virus (TMV) as a translational enhancer was added to construct. Transgenic tobacco plants expressing various levels of rhIL-11 protein were generated. Western blotting of the stably transformed lines demonstrated accumulation of the appropriately sized rhIL-11 protein in leaves. This research demonstrated the efficacy of using tobacco as an expression system for the production of rhIL-11.

• 한국해양공학회지
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• 제15권4호
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• pp.1-7
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• 2001

Mainly, Floating Breakwaters (FBs) have been constructed in many coastal regions due to the advantages of the coastal environment and construction cost. In general, the FB becomes fixed or its width broadened because the movement of the FB comes to be large and its the wave control function lower for the long period incident waves. This study discusses the wave control function of two-rowed Fixed Floating Breakwater (FFBs) that have narrower width than that of the one-rowed FFB by using numerical approach. Boundary Element Method (BEM) based on the Green formula and Eigenfunction Expansion Method (EEM) are applied to evaluate the three-dimensional wave transformation near the wave fields of two-rowed FFBs. The validity of the present study is confirmed by comparing it with the results of Ijima et al. (1974) and Yoshida et al. (1992) for the one-rowed Fixed Floating Structure. It is revealed that the wave control function of two-rowed FFBs is more effective than that of the one-rowed FFB.

• 한국정보과학회논문지:시스템및이론
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• 제31권3_4호
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• pp.187-194
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• 2004

쉬어-왑 분해 볼륨렌더링은 좋은 화질과 빠른 속도를 보이지만 대화형 분류 환경에서 메모리 참조 효율이 떨어지는 문제점이 있다. 본 논문에서는 대화형 분류 환경에서 효율적인 렌더링을 수행하기 위해 객체와 이미지에 대한 메모리 참조 공간 연관성을 갖는 알고리즘을 제안한다. 이를 위하여 쉬어-왑 분해에 회전을 추가한 확장 모델을 제안하여 객체와 이미지 모두에서 스캔라인 단위로 렌더링을 가능하게 한다. 또한 제안 모델이 가지고 있는 전후향 합성 혼란, 홀 발생, 계산 증가의 문제에 대한 원인을 제시하고 해결 방법을 보인다. 본 제안 모델은 렌더링 시 효율적 메모리 참조로 우수한 성능을 나타낸다.

• 한국정밀공학회지
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• 제28권3호
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• pp.377-382
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• 2011

Up to now, process design of multistage profile drawing from initial round material is performed through trial-and-error based on experience of industrial experts. This means the increase in production cost and excessive time consuming. In this study, process design program was developed for multistage profile drawing from initial round material. The program was made using VisualLISP. Therefore, the program can be operated by AutoCAD program. In order to verify the effectiveness of the program, two stage profile drawing process for producing heavy duty guide rail was design by using the program. In addition FE analysis and profile drawing experiment were performed. As a result, the program can be used in order to design profile drawing process design.

• Journal of Forest and Environmental Science
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• 제24권3호
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• pp.151-154
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• 2008

Dramatic price increases of fossil fuels and the economic development of emerging nations accelerates the transformation of forest lands into monocultures, e.g. for biofuel production. On this account, cost efficient methods to enable the monitoring of land resources has become a vital ambition. The application of remote sensing techniques has become an integral part of forest attribute estimation and mapping. The aim of this study was to evaluate the potentials of the kNN method by combining terrestrial with remotely sensed data for the development of a pixel-based monitoring system for the small scaled mosaic of different land use types of the off-reserve forests of the Goaso forest district in Ghana, West Africa. For this reason, occurrence and distribution of land use types like cocoa and non-timber forest resources, such as bamboo and raphia palms, were estimated, applying the kNN method to ASTER satellite data. Averaged overall accuracies, ranging from 79% for plantain, to 83% for oil palms, were found for single-attribute classifications, whereas a multi-attribute approach showed overall accuracies of up to 70%. Values of k between 3 and 6 seem appropriate for mapping bamboo. Optimisation of spectral bands improves results considerably.

• 아동학회지
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• 제37권1호
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• pp.7-16
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• 2016

Objective: It aimed at proposing the Korean Journal of Child Studies' strategy to be promoted to international journal based on the style and format of scholarly journals and journal metrics. Methods: The review of the journal in not only print version, but also an online version was done from the perspective of style and format. The total citation and impact factor were manually calculated from Web of Science Core Collection. Results: More professional level manuscript editing is required for maintaining the consistency of the style and format. The verso page and back matters should be improved to international level. Journal homepage should be reconstructed by adopting digital standards for the journal, including journal article tag suite, CrossMark, FundRef, ORCID, and text and data mining. To become an international journal, transformation into English journal and deposition to PubMed Central is mandatory. Conclusion: Since the editor's and society members' performance is top-notch, it will be possible to promote the journal up to international level soon. Society should guarantee the term of editor for enough time and support her with full cost and complete consent.

• Applied Science and Convergence Technology
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• 제23권1호
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• pp.14-26
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• 2014

Copper is an important component from coin metal to electronic wire, integrated circuit, and to lithium battery. Copper oxides, mainly including $Cu_2O$ and CuO, are important semiconductors for the wide applications in solar cell, catalysis, lithium-ion battery, and sensor. Due to their low cost, low toxicity, and easy synthesis, copper oxides have received much research interest in recent year. Herein, we review the crystallization of copper oxides by designing various chemical reaction routes, for example, the synthesis of $Cu_2O$ by reduction route, the oxidation of copper to $Cu_2O$ or CuO, the chemical transformation of $Cu_2O$ to CuO, the chemical precipitation of CuO. In the designed reaction system, ligands, pH, inorganic ions, temperature were used to control both chemical reactions and the crystallization processes, which finally determined the phases, morphologies and sizes of copper oxides. Furthermore, copper oxides with different structures as electrode materials for lithium-ion batteries were also reviewed. This review presents a simple route to study the reaction-crystallization-performance relationship of Cu-based materials, which can be extended to other inorganic oxides.

• Journal of Plant Biotechnology
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• 제41권1호
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• pp.50-55
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• 2014

Plant-based vaccines possess some advantages over other types of vaccine biotechnology such as safety, low cost of mass vaccination programs, and wider use of vaccines for medicine. This study was undertaken to develop the transgenic maize as edible vaccine candidates for humans. The immature embryos of HiII genotype were inoculated with A. tumefaciens strain C58C1 containing the binary vectors (V662 or V663). The vectors carrying nptII gene as selection marker and scEDIII (V662) or wCTB-scEDIII (V663) target gene, which code EIII proteins inhibite viral adsorption by cells. In total, 721 maize immature embryos were transformed and twenty-two putative transgenic plants were regenerated after 12 weeks selection regime. Of them, two- and six-plants were proved to be integrated with scEDIII and wCTB-scEDIII genes, respectively, by Southern blot analysis. However, only one plant (V662-29-3864) can express the gene of interest confirmed by Northern blot analysis. These results demonstrated that this plant could be used as a candidated source of the vaccine production.

• 한국정밀공학회지
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• 제21권6호
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• pp.188-196
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• 2004

The objective of this paper is to propose a new technology of the orthopaedic surgery using the combination of reverse engineering (RE) based on CT data and rapid prototyping (RP). The proposed technology utilizes symmetrical characteristics of the human body and capability of the combination of RE and RP, which rapidly manufactures three-dimensional parts from CT data. The original .stl data of injured extents are generated from the mirror transformation of .stl file fur uninjured extents. The physical shape before injuring is manufactured from RP using the original .stl data. Subsequently, pre-operative planning, such as a selection of proper implants, preforming of the implant, a decision of fixation locations and an insert position for the implant, an estimation of the invasive size, and pre-education of operators are performed using the physical shape. In order to examine the applicability and the efficiency of the proposed surgical technology, various case studies, such as a distal tibia commented fracture, a proximal tibia plateau fracture and an iliac wing fracture of pelvis, are carried out. From the results of case studies, it has been shown that the proposed technology is an effective surgical tool of the orthopaedic surgery reducing the operational time, the operational cost, the radiation exposure of the patient and operators, and morbidity. In addition, the proposed technology could improve the accuracy of operation and the speed of rehabilitation.

• 비파괴검사학회지
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• 제32권5호
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• pp.540-544
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• 2012

위상배열 기술에 기반을 둔 통상의 초음파검사에서처럼, 자왜형 원거리 초음파검사에서도 실시간 수신신호 처리를 위해 복잡한 전자회로들을 사용하여왔다. 본 연구는 위상 보상, 노이즈 필터링, 파형 변환 등과 같은 필수적인 작업들을 기존의 하드웨어 접근보다는 소프트웨어 접근을 이용하여 수행할 때, 보다 유연하고 효율적인 실시간 신호처리가 가능해진다는 것을 보여준다. 이는 비용효율적인 원거리 초음파검사 시스템 구축과 검사 결과 분석에 기여할 것이다.