• Journal of Preventive Veterinary Medicine
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• v.42 no.4
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• pp.163-170
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• 2018

The cost-effectiveness of foot-and-mouth disease (FMD) control strategies was evaluated using a simulation model fitted to the 2010/11 FMD epidemic in the city of Andong, Republic of Korea. Seven FMD-control strategies were evaluated with respect to the direct cost of a FMD-control strategy, such as slaughtering, movement restriction, and vaccination. All the strategies included pre-emptive slaughtering, movement restriction, and vaccination, but the levels of each control option were different. The simulated median cost of the baseline FMD-control strategy (three kilometers of pre-emptive slaughtering area, 100 days of movement restriction and vaccination of all FMD-susceptible animals in the study area) was estimated to be USD 99.7 million. When a five kilometer vaccination area was applied (with the other control measures being the same as the baseline strategy), the simulated median cost was reduced to USD 81.1 million from USD 99.7. The simulated median costs were USD 107.6 million for a five kilometer radius slaughtering area and USD 168.8 million for 60 days of movement restriction. The FMD-control strategy cost decreased with increasing number of farms depopulated per day. The probability of passive surveillance being effective or the probability of the successful implementation of movement restrictions were increased. Cost-effectiveness analysis is a suitable tool for evaluating the financial consequences of FMD-control strategies by comparing the cost of control strategies for a specific area.

• Advances in concrete construction
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• v.11 no.2
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• pp.99-109
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• 2021

Slag blended concrete is widely used as a mineral admixture in the modern concrete industry. This study shows an optimization process that determines the optimal mixture of air-entrained slag blended concrete considering carbonation durability, frost durability, CO2 emission, and materials cost. First, the aim of optimization is set as total cost, which equals material cost plus CO2 emission cost. The constraints of optimization consist of strength, workability, carbonation durability with climate change, frost durability, range of components and component ratio, and absolute volume. A genetic algorithm is used to determine optimal mixtures considering aim function and various constraints. Second, mixture design examples are shown considering four different cases, namely, mixtures without considering carbonation (Case 1), mixtures considering carbonation (Case 2), mixtures considering carbonation coupled with climate change (Case 3), and mixtures of high strength concrete (Case 4). The results show that the carbonization is the controlling factor of the mixture design of the concrete with ordinary strength (the designed strength is 30MPa). To meet the challenge of climate change, stronger concrete must be used. For high-strength slag blended concrete (design strength is 55MPa), strength is the control factor of mixture design.

• Journal of Biomedical Engineering Research
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• v.10 no.3
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• pp.361-364
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• 1989

A PC-based motor nerve conduction velocity measuring system was designed and constructed. The system was composed with an EMG preamplifier, a stimulator, an Apple II plus microcomputer and an 8 bit AD converter. The system was primariliy intended to screen motor nerve difficulties of industrial workers. This system can acquire, store and display the waveforms of evoked potentials. The PC-based system is expected to increase the versatility and applicability as well as to reduce the system cost.

• Journal of the Korean Data and Information Science Society
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• v.20 no.5
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• pp.887-894
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• 2009

The two-stage minimum risk point estimation of mean, the probability of success in a sequence of Bernoulli trials, is considered for the case where loss is taken to be symmetrized relative squared error of estimation, plus a fixed cost per observation. First order asymptotic expansions are obtained for large sample properties of two-stage procedure. Monte Carlo simulation is carried out to obtain the expected sample size that minimizes the risk and to examine its finite sample behavior.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.28 no.3
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• pp.110-114
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• 2016

Newly constructed multi-residential buildings with more than 500 households should be flushed out indoor contaminants using a mechanical ventilation system or large fans after the completion of construction and prior to occupancy by the Heath-friendly Housing Construction Standards since 2014. In addition, the standard recommends to maintain indoor temperature over $16^{\circ}C$ and relative humidity below 60% while performing the flush-out. However, it is difficult to maintain these recommended indoor conditions, especially during winter season because additional energy cost is needed for space heating. Therefore, in this study, additional energy cost including heating and ventilation energy cost in multi-residential household for flush-out during winter season was estimated using building energy simulation program called EnergyPlus. Additional energy cost according to various conditions for performing flush-out (such as performance period, ventilation rate, and heating set-point temperature) was analyzed. Based on the results of the energy simulation, the energy cost was estimated to be ranged from 14,625 to 29,452\/household in Incheon city and from 3,521 to 26,268\/household in Gwangju City. There was no significant change in energy cost according to the performing terms of flush-out between Incheon and Gwangju City.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2005.05a
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• pp.938-946
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• 2005

We study the firm's strategy to price its products and plan the spare parts manufacturing so as to maximize its profit and at the same time to fulfill its commitment to providing the customers with the key parts continuously over the relevant decision time horizon, i.e., the production plus warrantee period. To examine the research question, we developed and solved a two-stage optimal control theory model. Our analysis suggests that if the cost to produce the spare part during the warrantee period is more expensive than that during the production period, the firm should increase its sales price gradually throughout the production period to control its sales. In addition, during the production period it is optimal for the firm to produce the spare parts more than needed so that the overproduced spare parts can be used to partially meet the demand during the warrantee period. We conducted numerical analysis to investigate the sensitivity dynamics among key variables and parameters such as inventory holding cost, unit spare part production costs, part failure rate, and parameters in the demand function.

• Journal of Nutrition and Health
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• v.27 no.8
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• pp.864-871
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• 1994

The productivity and 13 influencing variables in 14 conventional hospital foodservice systems the total direct and non-direct labor hours required to produce and serve the total number of patient meals plus the number of cafeteria meals. Human resource variable significantly influencing the productivity level was the labor cost. As this index decreased, the meals served per human hour worked increased. System resource variables correlating significantly with productivity were the length of cycle menu, the ratio of staff meals, and modified patient meal ratio. As the length of cycle menu and the ratio of modified patient meal decreased, more meals were produced per human hour. However, as staff meal ratio increased, the meals served per human hour worked increased. The stepwise regression analysis suggests that around 53% of the variance in productivity is explained by labor cost.

• Journal of Advanced Navigation Technology
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• v.7 no.2
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• pp.156-161
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• 2003

In this study, a hybrid navigation system with a low-cost GPS Receiver plus Gyro and Odometer is developed and tested. This hybrid navigation system adopted a modified coupling method which can be distinguished from tightly coupled method or loosely coupled method, so that GPS receivers or Gyros or Odometers can be chosen arbitrary. Comparing to the existing hybrid navigation system, the test results show that this navigation system enhances the accuracy and is robust against the multipath error. It is also proven that this system has an advantage of acquiring GIS data for post processing.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.27 no.2
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• pp.7-13
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• 2013

The portion of lighting power consumption for our country is up to 20~30% of the total amount. Currently, most of the DSM(Demand side management) of lighting power is delivered in supply of high efficient lighting to customers. On the contrary, applications of lighting power to power load leveling are still rare. In this paper, the simulations for various control types of lighting power for load leveling are tried, and we obtained the cost effective and optimal control method through that. This simulation was executed in test office with fluorescent light by us based on applying 8 control types(on, off & dimming), considering customers' satisfaction, for instance, minimum intensity of illumination allowed. According to the result of this test, we found that mixed type(chessboard(on-off) plus dimming control(10%)) is most effective.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.3
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• pp.439-445
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• 2017

Objective: Production of alpha-1,3-galactosyltransferase (${\alpha}GT$)-deficient pigs is essential to overcome xenograft rejection in pig-to-human xenotransplantation. However, the production of such pigs requires a great deal of cost, time, and labor. Heterozygous ${\alpha}GT$ knockout pigs should be bred at least for two generations to ultimately obtain homozygote progenies. The present study was conducted to produce ${\alpha}GT$-deficient miniature pigs in much reduced time using mitotic recombination in neonatal ear skin fibroblasts. Methods: Miniature pig fibroblasts were transfected with ${\alpha}GT$ gene-targeting vector. Resulting gene-targeted fibroblasts were used for nuclear transfer (NT) to produce heterozygous ${\alpha}GT$ gene-targeted piglets. Fibroblasts isolated from ear skin biopsies of these piglets were cultured for 6 to 8 passages to induce loss of heterozygosity (LOH) and treated with biotin-conjugated IB4 that binds to galactose-${\alpha}$-1,3-galactose, an epitope produced by ${\alpha}GT$. Using magnetic activated cell sorting, cells with monoallelic disruption of ${\alpha}GT$ were removed. Remaining cells with LOH carrying biallelic disruption of ${\alpha}GT$ were used for the second round NT to produce homozygous ${\alpha}GT$ gene-targeted piglets. Results: Monoallelic mutation of ${\alpha}GT$ gene was confirmed by polymerase chain reaction in fibroblasts. Using these cells as nuclear donors, three heterozygous ${\alpha}GT$ gene-targeted piglets were produced by NT. Fibroblasts were collected from ear skin biopsies of these piglets, and homozygosity was induced by LOH. The second round NT using these fibroblasts resulted in production of three homozygous ${\alpha}GT$ knockout piglets. Conclusion: The present study demonstrates that the time required for the production of ${\alpha}GT$-deficient miniature pigs could be reduced significantly by postnatal skin biopsies and subsequent selection of mitotic recombinants. Such procedure may be beneficial for the production of homozygote knockout animals, especially in species, such as pigs, that require a substantial length of time for breeding.