• Anatomy and Cell Biology
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• v.57 no.1
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• pp.45-60
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• 2024

Morphologic changes in the brain through aging, as a physiologic process, may involve a wide range of variables including ventricular dilation, and sulcus widening. This study reports normal ranges of these changes as standard criteria. Normal brain computed tomography scans of 400 patients (200 males, 200 females) in every decade of life (20 groups each containing 20 participants) were investigated for subcortical/cortical atrophy (bicaudate width [BCW], third ventricle width [ThVW], maximum length of lateral ventricle at cella media [MLCM], bicaudate index [BCI], third ventricle index [ThVI], and cella media index 3 [CMI3], interhemispheric sulcus width [IHSW], right hemisphere sulci diameter [RHSD], and left hemisphere sulci diameter [LHSD]), ventricular symmetry. Distribution and correlation of all the variables were demonstrated with age and a multiple linear regression model was reported for age prediction. Among the various parameters of subcortical atrophy, BCW, ThVW, MLCM, and the corresponding indices of BCI, ThVI, and CMI3 demonstrated a significant correlation with age (R²≥0.62). All the cortical atrophy parameters including IHSW, RHSD, and LHSD demonstrated a significant correlation with age (R²≥0.63). This study is a thorough investigation of variables in a normal brain which can be affected by aging disclosing normal ranges of variables including major ventricular variables, derived ventricular indices, lateral ventricles asymmetry, cortical atrophy, in every decade of life introducing BW, ThVW, MLCM, BCI, ThVI, CMI3 as most significant ventricular parameters, and IHSW, RHSD, LHSD as significant cortical parameters associated with age.

• The Journal of the Korea Contents Association
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• v.12 no.6
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• pp.380-389
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• 2012

In this study, Systematic review and meta-analysis using the correlation coefficients was carried out to integrate precedent studies on factors affecting domestic occupational therapists' job stress. It aims at providing basic information resources of preventing and reducing stress of occupational therapists and effective counter-measurement to improve quality of occupational therapy and to establish efficient human resource management policy. Systematic review and meta-analysis were performed on eight thesis proven relevant to selection criteria in order to figure out correlation coefficients value by total, and factors correlation coefficients value. Also homogeneity test and publication bias test was performed too. The total correlation coefficients value of occupational therapists was .30 which was statistically significant. As to job stress factors, the organization related factor showed the highest correlation of coefficiency, followed by factors other than the organization related, physical environment, job related factor and personal factor. This research result can be used as a reference to prevent and reduce job stress of occupational therapists and to develop an effective measurement scheme.

• Physical Therapy Korea
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• v.24 no.2
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• pp.48-57
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• 2017

Background: Rounded shoulder posture (RSP), a postural abnormality, might cause shoulder pain and pathologic conditions. Although most previous research has investigated RSP focusing on the proximal structures of the shoulder, such as the scapula and pectoralis muscles, the relationship between RSP and anterior distal structures of the upper extremity, such as the biceps brachii muscle and elbow joint, is not clearly understood. Objects: This study aimed to investigate the correlations between RSP and the biceps brachii length, elbow joint angle (EJA), pectoralis minor length, general pectoralis major length, humeral head anterior translation (HHAT), glenohumeral internal rotation (IR), external rotation (ER), and horizontal adduction (HAD). Methods: Twelve subjects with RSP (6 male, 6 female) were recruited. All subjects fulfilled the RSP criteria indicated by a distance ${\geq}2.5cm$ from the posterior aspect of the acromion to the table in the supine position. The examiner measured each of the following parameters twice: RSP, biceps brachii length, EJA, pectoralis minor length, pectoralis major length, HHAT, glenohumeral IR, ER, and HAD. Pearson's correlation coefficient(r) was used to assess the correlation between RSP and all the variables. Results: There was a significant moderate positive correlation between RSP and biceps brachii length (r=.55, p=.032), moderate negative correlation between RSP and pectoralis minor length (r=-.62, p=.015), and moderate positive correlation between RSP and HHAT (r=.53, p=.038). Conclusion: The biceps brachii length, pectoralis minor length, and HHAT could be used to evaluate patients with RSP. Better understanding of the correlation between these factors and RSP could help in the development of effective methods to treat patients with this condition in clinical management.

• Journal of Environmental Health Sciences
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• v.47 no.1
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• pp.64-77
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• 2021

Objective: Biological monitoring of trace elements in human blood samples has become an important indicator of the health environment. The purpose of this study was to detect and evaluate multiple metal items in blood samples based on ICP-MS, to perform comparative evaluation with the existing analysis method, and to develop and verify a new method. Methods: 100 μL of whole blood from 80 healthy subjects was used to analyze ten metals (Sb, tAs, Cd, Pb, Mn, Hg, Mo, Ni, Se, Tl) using ICP-MS. Verification of the analysis method included calculation of linearity, accuracy, precision and detection limits. In addition, a comparative test with the conventional graphite furnace atomic absorption spectroscopy (GF-AAS) method was performed. In the case of Pb, Cd, and Hg in whole blood, cross-analysis between Pb, Cd, and Hg analysis methods was performed to confirm the difference between the existing method and the new method (ICP-MS). Results: The coefficient of determination (R2) was 0.999 or higher in seven items and 0.995 or higher in three items. The Pb result showed that Pearson's correlation coefficient was very high at 0.983, and the intraclass correlation coefficient was 0.966. The Cd result showed that Pearson's correlation coefficient was 0.917 between the existing method and the new analysis concentration value. Its intraclass correlation coefficient was 0.960, and there was no significant difference between the two groups. Hg had a low correlation at 0.687, and the intraclass correlation coefficient was 0.761, which was lower than that of Pb and Cd. The intra-day and inter-day accuracy of Pd and Cd were satisfactory, but Hg did not meet the criteria for both accuracy and precision when compared with the conventional analysis method. Conclusion: This study can be meaningful in that it proposes a more efficient and feasible analysis method by verifying a blood heavy metal concentration experiment using multiple simultaneous analyses. All samples were processed and analyzed using the new ICP-MS. It was confirmed that the agreement between the two methods was very high, with the agreement between the current and new methods being 0.769 to 0.998. This study proposes an efficient simultaneous methodology capable of analyzing multiple elements with small samples. In the future, studies of various applications and the reliability of ICP-MS analysis methods are required, and research on the verification of accurate, precise, and continuous analysis methods is required.

• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.1
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• pp.79-94
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• 2022

The demand for tunnel construction is increasing as part of underground space development due to urban saturation. The shield TBM method minimizes vibration and noise and minimizes ground deformation that occurs simultaneously with excavation, and shield TBM is generally applied to tunnel construction in urban areas. The importance of urban ground settlement prediction is increasing day by day, and in the case of shield TBM construction, ground deformation is minimized, but ground settlement due to tunnel excavation inevitably occurs. Therefore, in this study, the correlation between shield TBM, which is highly applicable to urban areas, and ground settlement is analyzed to suggest the shield TBM construction factors that have a major effect on ground settlement. Correlation analysis was performed between the shield TBM construction data and ground settlement measurement data collected at the actual site, and the degree of correlation was expressed as a correlation coefficient "r". As a result, the main construction factors of shield TBM affecting ground settlement were thrust force, torque, chamber pressure, backfill pressure and muck discharge. Based on the results of this study, it is expected to contribute to the presentation of judgment criteria for major construction data so that the ground settlement can be predicted and controlled in advance when operating the shield TBM in the future.

• Journal of Marine Life Science
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• v.9 no.1
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• pp.9-21
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• 2024

Paralytic shellfish poisoning (PSP) including Saxitoxin (STX) is caused by harmful algae, and poisoning occurs when the contaminated seafood is consumed. The mouse bioassay (MBA), a standard test method for detecting PSP, is being sanctioned in many countries due to its low detection limit and the animal concerns. An alternative to the MBA is the Neuro-2a cell-based assay. This study aimed to establish various test conditions for Neuro-2a assay, including cell density, culture conditions, and STX treatment conditions, to suit the domestic laboratory environment. As a result, the initial cell density was set to 40,000 cells/well and the incubation time to 24 hours. Additionally, the concentration of Ouabain and Veratridine (O/V) was set to 500/50 μM, at which most cells died. In this study, we identified eight concentrations of STX, ranging from 368 to 47,056 fg/μl, which produced an S-shaped dose-response curve when treated with O/V. Through inter-laboratory variability comparison of the Neuro-2a assay, we established five Quality Control Criteria to verify the appropriateness of the experiments and six Data Criteria (Top and Bottom OD, EC₅₀, EC₂₀, Hill slop, and R² of graph) to determine the reliability of the experimental data. The Neuro-2a assay conducted under the established conditions showed an EC₅₀ value of approximately 1,800~3,500 fg/μl. The intra- & inter-lab variability comparison results showed that the coefficients of variation (CVs) for the Quality Control and Data values ranged from 1.98% to 29.15%, confirming the reproducibility of the experiments. This study presented Quality Control Criteria and Data Criteria to assess the appropriateness of the experiments and confirmed the excellent repeatability and reproducibility of the Neuro-2a assay. To apply the Neuro-2a assay as an alternative method for detecting PSP in domestic seafood, it is essential to establish a toxin extraction method from seafood and toxin quantification methods, and perform correlation analysis with MBA and instrumental analysis methods.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.1 no.1
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• pp.37-49
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• 1994

The purpose of this study was to measure the oral temperature, skin temperature, and subjective discomfort according to the application time of ice bag on thigh, head, and abdomen. This study was also intended to suggest nursing principles about ice bag application by exploring the recovery time of skin temperature after the removal of ice bag. The design of this study was $8{\times}3$ factorial design with one sample repeated measure. Here, the application time of ice bag(criteria, 5min, 10min, 20min, 30min, 40min, 50min, 60min) and the application site of ice bag(thigh, head, abdomen) were independent variables. The subjects were 10 university woman students, and data collection was made from July, 1 to August 30, 1992. Rubber ice bag halfly filled with ice was covered with towel and applied on thigh, head and abdomen in other three days. Before applying the ice bag, oral temperature and skin temperature were checked for criteria. After ice bag was applied, skin temperature, oral temperature and VAS score were checked at first 5 minutes elapsed, and every 10 minutes until 60 minutes. After that, ice bag was removed, and oral temperature and skin temperature were also measured every ten minutes until 60 minutes. In this study, skin temperature and core temperature were measured by thermistor probe, and subjective discomfort was measured by 200mm VAS (Visual Analogue Scale). Some of the findings were as follows : 1. There were significant differences in skin temperature among the three application sites of ice bag as time go by. It was most decreased to $15.87^{\circ}C$ in thigh, and $19.47^{\circ}C$ in abdomen at 50 minutes after the application of ice bag, whereas $26.1^{\circ}C$ at 40 minutes in head. Before the application of ice bag, skin temperature showed significant differences in three sites, so that they were compared after the criteria was covariated. In other words, there was significantly more decrease of skin temperature in thigh and abdomen than head, after ice bag was applied for 20 minutes and more. 2. There was no significant difference in core temperature among the three application sites of ice bag during the time of application 3. There was no significant difference in subjective discomfort (VAS) among the three application sites of ice bag. 4. After the removal of ice bag, the recovery of skin temperature was significantly different in three sites during first 30 minutes. In head, skin temperature came up to criteria at 30 minutes after the removal of ice bag, but it was not recovered In thigh and abdomen even 60 minutes elapsed. 5. After the removal of ice bag, there was no significant difference in oral temperature among the three application sites of ice bag. 6. There was significant correlation between the skin temperature and VAS score only in thigh. In conclusion, it is suggested that head in more suitable site for the application of ice bag if it is used for the relief of fever or pain. When we apply ice bag on thigh or abdomen for the relief of pain, careful attention is required.

• Journal of Electrical Engineering and Technology
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• v.10 no.1
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• pp.288-294
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• 2015

Recently, the module-integrated converter has shown an interest in the photovoltaic generation system. In this system, the high frequency transformer should be compact and efficient. The proposed method is based on the correlation characteristic between the copper and core loss to minimize the loss of transformer. By sizing an effective cross-sectional area and window area of core, the amount of loss is minimized. This paper presents the design and analysis of high frequency transformer by using the 3D finite element model coupled with DC-DC converter circuit for more accurate analysis by considering the nonlinear voltage and current waveforms in converter circuit. The current waveform in each winding is realized by using the ideal DC voltage source and switching component. And, the thermal analysis is performed to satisfy the electrical and thermal design criteria.

• Structural Engineering and Mechanics
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• v.63 no.6
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• pp.799-808
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• 2017

Failure of a redundant long-span bridge is often described by innumerable failure modes, which make the structural system reliability analysis become a computationally intractable work. In this paper, an innovative procedure is proposed to efficiently identify the dominant failure modes and quantify the structural reliability for a long-span bridge system. The procedure is programmed by ANSYS and MATLAB. Considering the correlation between failure paths, a new branch and bound operation criteria is applied to the traditional stage critical strength branch and bound algorithm. Computational effort can be saved by ignoring the redundant failure paths as early as possible. The reliability of dominant failure mode is computed by FORM, since the limit state function of failure mode can be expressed by the final stage critical strength. PNET method and FORM for system are suggested to be the suitable calculation method for the bridge system reliability. By applying the procedure to a CFST arch bridge, the proposed method is demonstrated suitable to the system reliability analysis for long-span bridge structure.

• Transactions of the Korean Society of Mechanical Engineers
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• v.8 no.1
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• pp.10-17
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• 1984

The critical conditions marking the onset of thermally induced vortices over an inclined iso-thermal plate are investigated using the linear stability theory. The stability equations are simplified by estimating the orders of magnitude of respective terms. The analysis is carried out under the assumption that for the system of large Prandtl numbers temperature disturbances are initiated within the conventional thermal boundary layer of the basic flow. The stability criteria obtained from the present results agree well with those of the existing quasi-parallel flow models. In addition it is found that the critical conditions generate the heat transfer correlation in good agreement with experiments. Therefore, it is suggested that the validity of existing theoretical models will be reexamined.