• 제목/요약/키워드: Coronary Artery Bypass Grafting(CABG)

검색결과 120건 처리시간 0.03초

심한 좌심실 부전을 갖는 환자에서 시행한 Off-Pump CABG와 On-Pump CABG의 중단기 성적비교 (The Comparison Study of Early and Midterm Clinical Outcome of Off-Pump versus On-Pump Coronary Artery Bypass Grafting in Patients with Severe Left Ventricular Dysfunction (LVEF${\le}35{\%}$))

  • 윤영남;이교준;배미경;심영희;유경종
    • Journal of Chest Surgery
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    • 제39권3호
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    • pp.184-193
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    • 2006
  • 배경: 심장박동 상태에서 시행하는 관상동맥우회술(Off pump coronary artery bypass grafting, OPCAB) 은 심폐체외순환 하에서 시행하는 관상동맥우회술(On pump coronary artery bypass grafting, On pump CABG)에 비해 합병증이 다소 적은 것으로 보고되고 있다. 저자들은 좌심실 기능이 저하된 환자들에서 OPCAB과 On pump CABG의 단기 및 중기 성적을 평가하여 OPCAB의 유용성을 확인하였다. 대상 및 방법: 2001년 1월부터 2005년 2월까지 동반수술을 시행 받지 않고 관상동맥우회술만을 시행 받은 946명 중 좌심실 박출계수가 $35\%$ 이하인 100명을 대상으로 하였다(OPCAB군 : On pump CABG군 =68명: 32명). 평균 연령은 두 군이 OPCAB군과 On pump CABG군이 각각 62.9$\pm$9.0세와 63.8 $\pm$ 8.0로 두 군의 차이가 없었다. 두 군의 수술 전 위험요인을 분석하고, 수술 결과 및 추적결과를 평가 및 비교하였다. 결과: OPCAB군은 평균 2.75$\pm$0.72개, On pump CABG군은 2.78$\pm$0.55개의 도관을 획득하여, 각각 3.00$\pm$0.79개, 3.16$\pm$0.72개의 원위문합을 시행하였다. 수술 후 사망은 OPCAB군에서만 1명 ($1.5\%$) 발생하였으나 두 군간의 통계적 유의성은 없었다. 수술시간, 수술 후 1일째 CK-MB, 수술 후 기계 환기 시간, 중환자실 체류기간, 합병증 발생률이 통계적으로 유의하게 OPCAB군에서 더 낮았다. 평균 추적 기간은 26.6$\pm$12.8개월(4${\~}$54개월)이었으며, 추적 기간 중 좌심실 박출계수는 OPCAB군과 On pump CABG군이 각각 $27.1\pm4.5\%$$26.9\pm5.4\%$에서 $40.7\pm13.0\%$$33.3\pm13.7\%$로 통계적으로 유의하게 각각 증가하였다. 4년 생존율은 OPCAB군과 On pump CABG군이 각각 $92.2\%,\;88.3\%$, 심장관련 사망에 있어서 4년 freedom rate은 각각 $97.7\%,\;96.4\%$로 두 군간의 차이는 없었으며, 심장관련 합병증과 협심증 발생의 freedom rate도 두 군간의 차이는 없었다. 결론: 좌심실 기능이 저하된 환자들에서 심장박동 상태에서 시행하는 관상동맥우회술은 심장기능을 향상시키고 On pump CABG군에 비해 우수한 수술결과를 보였다. 특히 On pump CABG군에 비해 우수한 단기 성적을 보였으나 중기성적은 차이가 없었다. 따라서 좌심실 기능이 저하된 환자들에 있어서 심장박동 상태에서 시행하는 관상동맥우회술은 안전하고 효과적으로 사용될 수 있는 수술방법이라고 생각한다.

Trends in Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery in Korea

  • Lee, Heeyoung;Lee, Kun Sei;Sim, Sung Bo;Jeong, Hyo Seon;Ahn, Hye Mi;Chee, Hyun Keun
    • Journal of Chest Surgery
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    • 제49권sup1호
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    • pp.60-67
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    • 2016
  • Background: Coronary angioplasty has been replacing coronary artery bypass grafting (CABG) because of the relative advantage in terms of recovery time and noninvasiveness of the procedure. Compared to other Organization for Economic Cooperation and Development (OECD) countries, Korea has experienced a rapid increase in coronary angioplasty volumes. Methods: We analyzed changes in procedure volumes of CABG and of percutaneous coronary intervention (PCI) from three sources: the OECD Health Data, the National Health Insurance Service (NHIS) surgery statistics, and the National Health Insurance claims data. Results: We found the ratio of procedure volume of PCI to that of CABG per 100,000 population was 19.12 in 2014, which was more than triple the OECD average of 5.92 for the same year. According to data from NHIS statistics, this ratio was an increase from 11.4 to 19.3 between 2006 and 2013. Conclusion: We found that Korea has a higher ratio of total procedure volumes of PCI with respect to CABG and also a more rapid increase of volumes of PCI than other countries. Prospective studies are required to determine whether this increase in absolute volumes of PCI is a natural response to a real medical need or representative of medical overuse.

Association Between the Frailty Index and Clinical Outcomes after Coronary Artery Bypass Grafting

  • Kim, Chan Hyeong;Kang, Yoonjin;Kim, Ji Seong;Sohn, Suk Ho;Hwang, Ho Young
    • Journal of Chest Surgery
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    • 제55권3호
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    • pp.189-196
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    • 2022
  • Background: This study investigated the predictive value of the frailty index calculated using laboratory data and vital signs (FI-L) in patients who underwent coronary artery bypass grafting (CABG). Methods: This study included 508 patients (age 67.3±9.7 years, male 78.0%) who underwent CABG between 2018 and 2021. The FI-L, which estimates patients' frailty based on laboratory data and vital signs, was calculated as the ratio of variables outside the normal range for 32 preoperative parameters. The primary endpoints were operative and medium-term all-cause mortality. The secondary endpoints were early postoperative complications and major adverse cardiac and cerebrovascular events (MACCEs). Results: The mean FI-L was 20.9%±10.9%. The early mortality rate was 1.6% (n=8). Postoperative complications were atrial fibrillation (n=148, 29.1%), respiratory complications (n=38, 7.5%), and acute kidney injury (n=15, 3.0%). The 1- and 3-year survival rates were 96.0% and 88.7%, and the 1- and 3-year cumulative incidence rates of MACCEs were 4.87% and 8.98%. In multivariable analyses, the FI-L showed statistically significant associations with medium-term all-cause mortality (hazard ratio [HR], 1.042; 95% confidence interval [CI], 1.010-1.076), MACCEs (subdistribution HR, 1.054; 95% CI, 1.030-1.078), atrial fibrillation (odds ratio [OR], 1.02; 95% CI, 1.002-1.039), acute kidney injury (OR, 1.06; 95% CI, 1.014-1.108), and re-operation for bleeding (OR, 1.09; 95% CI, 1.032-1.152). The minimal p-value approach showed that 32% was the best cutoff for the FI-L as a predictor of all-cause mortality post-CABG. Conclusion: The FI-L was a significant prognostic factor related to all-cause mortality and postoperative complications in patients who underwent CABG.

경피적 관상동맥 성형술의 실패에 의해 발생한 응급환자의 임상경과 (Clinical Outcome of Emergency Coronary Artery Bypass Grafting after Failed Percutaneous Transluminal Coronary Angioplasty)

  • 김도균;유경종;윤영남;이기종;이식;장병철;강면식
    • Journal of Chest Surgery
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    • 제40권3호
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    • pp.209-214
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    • 2007
  • 배경: 경피적 관상동맥 성형술(angioplasty, translumial, percutaneous coronary, PTCA)은 현재 거의 모든 관상동맥 협착증 환자에서 시도되고 있다. 따라서 PTCA 실패로 인한 치명적인 응급 상황도 나타나고 있다. 이 연구에서는 PTCA의 실패로 응급 관상동맥 우회술이 필요했던 환자의 임상결과를 분석하고자 한다. 대상 및 방법: 1988년 5월부터 2005년 5월까지 총 5,712예의 PTCA를 시행했고 그 중 실패 후 발생한 응급 환자는 84명(1.4%)이었고 이 중 응급 수술이 가능했던 27명(32.1%)을 대상으로 하였다. 환자들의 평균 연령은 $63.7{\pm}8.9\;(46{\sim}80)$세이었고, 그 중 남자가 14명(51.9%)이었다. PTCA 전 진단은 급성 심근경색(12명), 불안정형 협심증(13명), 안정형 협심증(2명)이었다. 결과: PTCA 실패의 원인으로는 새로운 색전에 의한 관상동맥 폐쇄가 4명, 시술 도중 관상동맥 박리가 17명, 관상동맥 파열이 3명, 기타가 3명이었다. 수술이 가능했던 환자들은 6시간 내로 응급수술을 시행했고 그 중 22명은 고식적 관상동맥 우회술(coronary artery bypass grafting, CABG)을 받았고 5명은 off-pump CABG (OPCAB)을 받았다. 평균 사용된 이식편의 수는 $2.58{\pm}0.95$개였다. 수술 환자 중에서는 18.5%의 사망률을 보였다(5/27). 단변량 분석에서는 수술 환자들의 사망률은 좌전하행지 침범유무, 수술 전 쇼크상태, 수술 후 2가지 이상의 수축 촉진제의 사용, 수술 후에도 대동맥 풍선 펌프를 사용한 경우가 통계적으로 유의하게 나타났다. 결론: PTCA는 환자들이 수술에 비해 상대적으로 안전하다고 생각하지만 PTCA 실패로 인한 응급상황이 발생 시에는 매우 높은 사망률을 보이며 관상동맥 우회술을 시행하더라도 수술 사망률 및 수술 부작용이 상대적으로 높다. 따라서, 치명적인 합병증이 생길 수 있으므로 신중한 환자의 선택이 요구되며 합병증의 발생 시 적극적인 수술 치료를 준비해야 한다.

Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and Predictors of Mortality

  • Cho, Won-Chul;Yoo, Dong-Gon;Kim, Joon-Bum;Lee, Jae-Won;Choo, Suk-Jung;Jung, Sung-Ho;Chung, Cheol-Hyun
    • Journal of Chest Surgery
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    • 제44권2호
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    • pp.131-136
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    • 2011
  • Background: We evaluated the surgical results and predictors of long-term survival in patients who underwent coronary artery bypass grafting (CABG) at the time of an aortic valve replacement (AVR) due to aortic stenosis. Materials and Methods: Between January 1990 and December 2009, 183 consecutive patients underwent CABG and concomitant aortic valve replacement for aortic stenosis. The mean follow-up period was $59.8{\pm}3.3$ months and follow-up was possible in 98.3% of cases. Predictors of mortality were determined by Cox regression analysis. Results: There were 5 (2.7%) in-hospital deaths. Follow-up of the in-hospital survivors documented late survival rates of 91.5%, 74.8%, and 59.6% at 1, 5, and 10 postoperative years, respectively. Age (p<0.001), a glomerular filtration rate (GFR) less than 60 mL/min (p=0.006), and left ventricular (LV) mass (p<0.001) were significant predictors of mortality in the multivariate analysis. Conclusion: The surgical results and long-term survival of aortic valve replacement with concomitant CABG in patients with aortic stenosis and coronary artery disease were acceptable. Age, a GFR less than 60 mL/min, and LV mass were significant predictors of mortality.

Graft Patency of No-Touch Saphenous Veins Used as Aortocoronary Bypass Grafts

  • Jeongwon Kim;Suk Ho Sohn;Jae-Sung Choi;Se Jin Oh;Ho Young Hwang
    • Journal of Chest Surgery
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    • 제56권5호
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    • pp.313-321
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    • 2023
  • Background: This study evaluated the early, 1-year, and 3-year graft patency rates and mid-term clinical outcomes after no-touch saphenous veins (NT-SVs) were used as aortocoronary grafts in coronary artery bypass grafting (CABG). Methods: In total, 101 patients who underwent CABG using NT-SVs as aortocoronary grafts were included. The 2 most common indications for performing aortocoronary grafting with NT-SVs were unavailability of the left internal thoracic artery (n=36) and moderate lesions where flow competition was expected (n=27). Early (median, 1 day; interquartile range [IQR], 1-2 days), 1-year (median, 13 months; IQR, 11-16 months), and 3-year (median, 34 months; IQR, 27-41 months) graft angiography was performed in 98 (97.0%), 84 (83.2%), and 40 patients (39.6%), respectively. The median follow-up duration was 43 months (IQR, 13-76 months). Overall survival rates and the cumulative incidence of major adverse cardiac events were evaluated. Results: The operative mortality rate was 2% (2 of 101 patients). Early postoperative patency rates for overall and aortocoronary NT-SV grafts were 98.2% (223 of 227 distal anastomoses) and 98.2% (164 of 167), respectively. The 1- and 3-year patency rates for aortocoronary SV grafts were 94.9% (131 of 138) and 90.6% (58 of 64), respectively. The overall survival rates at 5 and 10 years were 81.7% and 59%, respectively. The cumulative incidence of major adverse cardiac events at 5 and 10 postoperative years was 20.7% and 39%, respectively. Conclusion: The feasibility of using NT-SVs as aortocoronary grafts in CABG was shown in this study, based on the graft patency rates up to 3 years and the mid-term clinical outcomes.

심폐바이패스 없이 시행한 관상동맥 우회술 100예의 임상적 고찰 (Clinical Results of 100 Cases of Coronary Artery Bypass Grafting without Cardiopulmonary Bypass)

  • 방정희;우종수
    • Journal of Chest Surgery
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    • 제37권4호
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    • pp.322-327
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    • 2004
  • 심폐바이패스 없이 시행하는 관상동맥 우회술은 이제 심장수술자에게 일반적인 시술이 되었다. 저자들은 이 수술방법의 합병증 및 사망률을 분석하여 수술의 안정성 및 효능성을 알아보고자 했다. 대상 및 방법: 1999년 6월부터 2002년 8월까지의 심폐바이패스 없이 시행한 관상동맥 우회로술 100예와 심폐바이패스하의 관상동맥 우회로술 100예를 대상으로 했으며 관상동맥 수술 외에 다른 수술을 동반한 경우는 제외하였다. 결과: 양 그룹에서 술 전 위험요소나 관상동맥 질환 정도의 차이는 없었다. 심폐바이패스 없이 시행한 관상동맥 우회술에서 심폐바이패스하의 관상동맥 우회술보다 평균수술 시간(295$\pm$73분 vs 323$\pm$83분, p>0.05)과 평균 입원 기간(15.34$\pm$6.02일 vs 13.80$\pm$4.95일, p>0.05)은 유의한 차이가 없었으나, 평균 인공 호흡기 거치 시간은 심폐바이패스 없이 수술한 경우에 의미 있게 짧았다. (17.3$\pm$11.27시간 vs 24.98$\pm$16.1시간, p<0.05) 심폐바이패스 없이 시행한 관상동맥 우회술 중 술 중 심폐바이패스로 전환한 예는 없었다. 술 중 혈역학적인 불안정을 보인 경우는 6예에서 있었는데 2예는 둔각분지 시 4예는 우관상동맥 문합 시 생겼다. 술 후 사망은 심폐바이패스 없이 시행한 관상동맥 우회술 시 1예, 심폐바이패스하의 관상동맥 우회술 시 2예가 있었다. 대동맥 내 풍선펌프는 각각 1예와 2예가 있었다. 술 후 뇌경색은 심폐바이패스 없이 시행한 관상동맥 우회술에서는 없는 반면 심폐바이패스하의 관상동맥 우회술에서는 2예가 있었다. 술 후 심부정맥은 각각 4예와 6예 있었으며 급성 신기능 부전은 각각 3예와 2예가 있었다. 결론: 심폐바이패스 없이 시행한 관상동맥 우회로술은 술 후 합병증 및 사망률, 환자의 회복과정에서 안전하고 효율적인 수술방법으로 생각된다.

관상동맥 협착증의 외과적 치험 -30례의 임상적 결과- (Surgical Treatment of Coronary Artery Occlusive Disease)

  • 김병열
    • Journal of Chest Surgery
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    • 제28권11호
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    • pp.994-1000
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    • 1995
  • Thirty patients with ischemic heart disease underwent coronary artery bypass grafting [CABG from 1985 through 1994. There were 16 males and 14 females whose age ranged from 41 to 72 years old. Preoperative diagnoses were unstable angina in 13 of patients, stable angina in 8, postmyocardial infarction state in 7, and state of failed percutaneous transluminal coronary angioplasty [ PTCA in 2. The patterns of disease were single vessel involvement [ 17cases , double vessel involvement [ 7 cases , triple vessel involvement [ 3 cases , Lt main lesion including Lt. ostial lesion [ 3 cases . Saphenous vein grafts were used in 27/30 patients [ 90% , and internal mammary artery grafts were used in 6/30 patients [ 20% . The hospital mortality was 13.3% and all survivors were asymptomatic and improved over their preoperative status.

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Neo-ostium Formation in Anomalous Origin of the Left Coronary Artery

  • Han, Woo-Sik;Park, Pyo-Won;Cho, Seong-Ho
    • Journal of Chest Surgery
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    • 제44권5호
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    • pp.355-357
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    • 2011
  • Anomalous origin of a coronary aortic artery is a rare cardiac anomaly. Although it can cause angina, syncope, and palpitations, most patients are asymptomatic. This anomaly requires surgical treatment or intervention because it is associated with sudden death. Several surgical techniques, such as coronary reimplantation, coronary artery bypass grafting (CABG), unroofing, and neo-ostium formation, have been proposed as treatments. We report a case surgically treated with neo-ostium formation in anomalous origin of the left coronary artery from the right coronary sinus.

Transpedal lymphatic embolization for lymphorrhea at the graft harvest site after coronary artery bypass grafting

  • Cha, Jung Guen;Lee, Sang Yub;Hong, Jihoon;Ryeom, Hun Kyu;Kim, Gab Chul;Do, Young Woo
    • Journal of Yeungnam Medical Science
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    • 제38권1호
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    • pp.74-77
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    • 2021
  • Lymphorrhea is a rare but potentially severe complication that occurs after various surgical procedures. Untreated lymphorrhea may lead to wound dehiscence, infection, and prolonged hospital stay. Currently, there is no standard effective treatment. Early management usually includes leg elevation, drainage, and pressure dressing. However, these methods are associated with prolonged recovery and high recurrence rates. We report a case of lymphorrhea from a calf wound after endoscopic great saphenous vein (GSV) harvesting for coronary artery bypass grafting (CABG). The patient presented with intractable oozing from the postoperative wound on the right calf. Lymphorrhea persisted for 6 weeks despite negative-pressure wound therapy with a long-acting somatostatin. We performed unilateral pedal lymphangiography that confirmed wound lymphorrhea, followed by glue embolization. No recurrence was observed after 8 months of follow-up. This case report demonstrates the successful use of lymphangiography with glue embolization in the control of lymphorrhea after GSV harvesting for CABG.