• Journal of the Korean Institute of Landscape Architecture
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• v.32 no.2
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• pp.120-129
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• 2004

This study was carried out to develop new varieties with early maturing and large fruit size in the Korean native dogwood (Cornus kousa) for woody landscape plants from native sites or cultivated area. The results are obtained as follows; We selected strains with early maturing and large fruit. size from the habitats from 2000 to 2003. ‘SKK 2-1’ had 4.0cm of fruit size while 2.0 cm of native variety. In addition, ‘SKK 2-2’, ‘SKK 2-3’, ‘SKK 2-4’, and ‘SKK 2-5’ with large fruit and early maturing were preliminary selected from the habitats. In the preliminary selections, ‘SKK 2-1’ was finally selected as new early maturing variety with large fruits in 2003. New early maturing variety with large fruit size, C. kousa var. ‘SKK 2-1’ was selected from 200 plants of 5-year-old seedlings in C. kousa in 5-12 Nung wean ri Goo sung myun Yong In, Kyung gi do, Korea in 2000. Their fruits were colorized in September 18, 20∼25 days earlier than October 7 of native varieties. Its fruit diameter is larger than 4cm. Its fruit weight was 5 times as heavy as native cultivars grown in Korea. This useful characters were still inherited after grafting. However, characteristics of growth, leaf, flower, and flowering period were not different from those of native varieties. Therefore, it was very promising landscape woody plant, having large fruits in early fall season. The rooting rate of Korean dogwood was high by the IBA treatment. The optimum date for softwood cutting was on June 25 ∼ July 25 when the rooting rate was more than 80%. In addition. Korean dogwood was easily propagated by grafting. Therefore, new early maturing variety with large fruits, C. kousa var. ‘SKK 2-1’ is easily propagated by softwood cutting or grafting and then is a promising cultivar as a woody landscape plant.

• Korean Journal of Medicinal Crop Science
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• v.10 no.5
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• pp.327-332
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• 2002

This study was conducted to investigate the immuno-regulatory effect and apoptosis of L1210 and HL60 leukemia cells of methanol-extracts of Cornus kousa Burg(CKB). The proliferation of mouse splenocytes and thymocytes enhanced by the addition of $10\;{\mu}g/ml$ of CKB. CKB were administered p.o. once a day for 7 days in adult male BALB/c mice. CKB increased the splenic and thymic T lymphocytes, especially the number of $T_H$ cells markedly increased by the treatment of CKB. CKB treatment induced the apoptotic cell death in L1210 mouse leukemia and HL60 human leukemia cells. In addition, CKB also accelerated the phagocytic activity in peritoneal macrophages and increased the production of plaque forming cells. These results suggest that CKB have an various immuno-regulatory property.

• Journal of Applied Biological Chemistry
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• v.58 no.4
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• pp.317-323
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• 2015

The extracted phenolic compounds from Cornus kousa fruit for biological activities as functional resources were examined. The phenolic compounds which were extracted with water and 40% ethanol from Cornus kousa fruit were $7.04{\pm}0.27$ and $4.47{\pm}0.18mg/g$, respectively. The 1,1-diphenyl-2-picrylhydrazyl free radical scavenging activity of water and ethanol extracts were 84% and 86% at $50{\mu}g/mL$phenolics, respectively. The 2,2'-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid radical decolorization activity of water and ethanol extracts were 84 and 95% at $100{\mu}g/mL$ phenolics, respectively. Antioxidant protection factor in water and ethanol extracts at $50{\mu}g/mL$ phenolics were 1.93 and 1.82 PF, respectively. Thiobarbituric acid reactive substance were 69% in water extracts and 89% in ethanol extracts at $150{\mu}g/mL$ phenolics. The inhibition activity on xanthine oxidase in water and ethanol extracts was 34 and 60%, respectively. The inhibition activity on ${\alpha}$-glucosidase was 29% in water extracts and 87% in ethanol extracts. The tyrosinase inhibitory activity was 19% in ethanol extracts. The collagenase inhibition activity of anti-wrinkle effect showed an excellent wrinkle improvement effect as 53% in water extracts and 77% in ethanol extracts at $200{\mu}g/mL$ phenolics. The hyaluronidase inhibition activity as antiinflammation effect of water extracts was confirmed to 34% of inhibition at $200{\mu}g/mL$ phenolic. The results can be expected extracts from Cornus kousa fruit to use as functional resource for antioxidant, antigout, inhibitor of carbohydrate degradation, antiwrinkle activity and antiinflammation activity.