• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.139.2-139.2
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• 2008

• Journal of Genetic Medicine
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• 제16권1호
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• pp.23-26
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• 2019

Thrombophilia refers to inherited or acquired hemostatic disorders that result in a predisposition to blood clot formation. When combined with the hypercoagulable state that is characteristic of pregnancy, there is an increased risk of severe and recurrent pregnancy complications. Activated protein C resistance caused by factor V Leiden (FVL) mutation is known to be the most common cause of inherited thrombophilia in Caucasian population. FVL mutation has been related to pregnancy complications associated with hypercoagulation, e.g. miscarriage, intrauterine fetal demise, placental abruption, and intrauterine growth retardation. Although the FVL mutation is easily detected using molecular DNA techniques, patients who are heterozygous for this disorder often remain asymptomatic until they develop a concurrent prothrombotic condition. Because there are potentially serious effects of FVL mutation for pregnancy, and because effective treatment strategies exist, early detection and treatment of this condition might be considered.

• 한국인터넷방송통신학회논문지
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• 제24권4호
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• pp.49-55
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• 2024

코드 스멜은 Kent Beck에 의해 사용된 개념으로, 잠재적인 품질 문제를 나타내며 리팩토링의 필요성을 제시한다. 본 논문은 LEA 코드베이스에서 코드 스멜을 평가하며, 분류와 관련된 메트릭에 중점을 둔다. 연구에서는 LEA_core.c와 LEA.cpp를 분석하여 코드 품질과 복잡성의 차이를 강조한다. 또한 연구에서는 LOC, NOM, NOA, CYCLO, MAXNESTING, FANOUT와 같은 메트릭을 사용하여 크기, 복잡성, 결합도, 캡슐화, 상속, 응집도를 평가한다. 연구 결과에서는 LEA_core.c가 LEA.cpp에 비해 더 복잡하고 유지보수가 어려운 것으로 나타났다. 우리는 향후 연구에서 실시간 코드 스멜 탐지 및 리팩토링 제안을 위한 자동화 도구를 개발할 것이다.

• 대한임베디드공학회논문지
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• 제13권5호
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• pp.225-234
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• 2018

Control flow errors are caused by the vulnerability of memory and result in system failure. Signature-based control flow monitoring is a representative method for alleviating the problem. The method commonly consists of two routines; one routine is signature update and the other is signature verification. However, in the existing signature-based control flow monitoring, monitoring target application is tightly combined with the monitoring code, and the operation of monitoring in a single thread is the basic model. This makes the signature-based monitoring method difficult to expect performance improvement that can be taken in multi-thread and multi-core environments. In this paper, we propose a new signature-based control flow monitoring model that separates signature update and signature verification in thread level. The signature update is combined with application thread and signature verification runs on a separate monitor thread. In the proposed model, the application thread and the monitor thread are separated from each other, so that we can expect a performance improvement that can be taken in a multi-core and multi-thread environment.

• 센서학회지
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• 제21권5호
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• pp.339-344
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• 2012

This article describes a novel method for the detection of amyloid-${\beta}$($A{\beta}$) peptide that utilizes a photo-sensitive field-effect transistor (p-FET). According to a recent study, $A{\beta}$ protein has been known to play a central role in the pathogenesis of Alzheimer's disease (AD). Accordingly, we investigated the variation of photo current generated from p-FET with and without intracellular magnetic beads conjugated with $A{\beta}$ peptides, which are placed on the p-FET sensing areas. The decrease of photo current was observed due to the presence of the magnetic beads on the channel region. Moreover, a similar characteristic was shown when the Raw 264 cells take in magnetic beads treated with $A{\beta}$ peptide. This means that it is possible to simply detect a certain protein using magnetic beads and a p-FET device. Therefore, in this paper, we suggest that our method could detect tiny amounts of $A{\beta}$ for early diagnosis of AD using the p-FET devices.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2017년도 춘계학술대회
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• pp.379-382
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• 2017

전 세계적으로 해운물류 안전 보안체계가 강화됨에 따라 국가물류보안 체계 구축을 위한 해운물류안전 보안 핵심기술 개발이 이루어지고 있다. 또한 미국에서 2018년 시행예정인 컨테이너 사전 100% 전수검사에 대응하기 위한 컨테이너 검색기의 핵심구성 요소인 Array 검출 System의 국산화 개발이 필요하다. 본 논문에서는 현재 자체 개발한 Test Digital 신호처리 Board를 가지고 TI-RTOS(Texas Instruments - Real Time Operating System)를 이용하여 개발한 Test Software Program을 제안한다.

• Archives of Pharmacal Research
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• 제19권6호
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• pp.469-474
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• 1996

A rapid and sensitive method has been developed to detect hepatitis B virus DNA (HBV) by nested polymerase chain reaction (PCR) technique with primers specific for the surface and core regions in capillary thermal cycler within 80 min. The lower limit for detection by present PCR method is $10^{-5}$ pg of recombinant HBV DNA which is equivalent to that determined by one round of PCR amplification and Southern blot hybridization analysis. When boiled HBV positive serum was serially diluted 10-fold, HBV DNA was successfully determined in $1{\mu}l-10^{-3}$ of serum. HBV DNA was detected by present method in 69 clinical samples including HBsAg positives and negatives by enzyme-linked immunosorbent assay (ELISA). When serum samples were amplified by nested PCR using surface and core region primers, HBV DNAs were detected in 37 of 69 samples (53.6%) and 18 of 69 samples (26.1%), respectively. These results can inform the infectious state of HBsAg positive pateints. A simple and rapid nested PCR protocol by using boiled serum as DNA template has been described for the clinical utility to determine HBV DNA in human serum.

• 대한수의학회지
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• 제59권1호
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• pp.37-42
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• 2019

Worldwide, avian influenza H9N2 viruses of different lineages are the most widespread viruses in poultry. However, to date, cases in Russia have not been documented. In this study, we report the first detection of a G1-like H9N2 virus from poultry sampled at live-bird markets in Russia (Far East region) during the winter of 2018 (isolate A/chicken/Amur_Russia/17/2018). We assume there has been further circulation of the A/chicken/Amur_Russia/17/2018 H9N2 virus in the Russian Far East with possible distribution to other regions or countries in 2018-2019.

• Journal of Veterinary Science
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• 제21권2호
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• pp.31.1-31.5
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• 2020

In this study, whiteleg shrimp (Penaeus vannamei) imported from Vietnam were collected from South Korean markets, and examined for 2 viruses: infectious hypodermal and hematopoietic necrosis virus (IHHNV, recently classified as decapod penstyldensovirus-1), and white spot syndrome virus (WSSV). Among 58 samples, we detected IHHNV in 23 samples and WSSV in 2 samples, using polymerase chain reaction and sequencing analyses. This is the first report of IHHNV and WSSV detection in imported shrimp, suggesting that greater awareness and stricter quarantine policies regarding viruses infecting shrimp imported to South Korea are required.

• ETRI Journal
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• 제31권1호
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• pp.92-94
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• 2009

We propose a system for mobile-phone fraud detection based on a bidirectional artificial neural network (bi-ANN). The key advantage of such a system is the ability to detect fraud not only by offline processing of call detail records (CDR), but also in real time. The core of the system is a bi-ANN that predicts the behavior of individual mobile-phone users. We determined that the bi-ANN is capable of predicting complex time series (Call_Duration parameter) that are stored in the CDR.