• Molecules and Cells
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• v.28 no.3
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• pp.139-148
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• 2009

Cell death has been traditionally classified in apoptosis and necrosis. Apoptosis, known as programmed cell death, is an active form of cell death mechanism that is tightly regulated by multiple cellular signaling pathways and requires ATP for its appropriate process. Apoptotic death plays essential roles for successful development and maintenance of normal cellular homeostasis in mammalian. In contrast to apoptosis, necrosis is classically considered as a passive cell death process that occurs rather by accident in disastrous conditions, is not required for energy and eventually induces inflammation. Regardless of different characteristics between apoptosis and necrosis, it has been well defined that both are responsible for a wide range of human diseases. Glycogen storage disease type I (GSD-I) is a kind of human genetic disorders and is caused by the deficiency of a microsomal protein, glucose-6-phosphatase-${\alpha}$ ($G6Pase-{\alpha}$) or glucose-6-phosphate transporter (G6PT) responsible for glucose homeostasis, leading to GSD-Ia or GSD-Ib, respectively. This review summarizes cell deaths in GSD-I and mostly focuses on current knowledge of the neutrophil apoptosis in GSD-Ib based upon ER stress and redox signaling.

• Journal of muscle and joint health
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• v.20 no.1
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• pp.22-30
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• 2013

Purpose: The International Classification of Functioning, Disability and Health (ICF) model was proposed by the World Health Organization for enhancing interdisciplinary communication. The purpose of this study was to examine the functional status of acute stroke patients using ICF core sets-short form. Methods: A set of 15 ICF items on functional status was used by nurses for their daily nursing assessment on functional status in 44 acute stroke patients in a university hospital. Results: The highest level of function was "consciousness", while the lowest was "defecation". Compared with functional status on the first day, consciousness, ingestion, language (mental), and defecation functions were significantly improved on the 14th day. However, there was no significant changes in items on activity and participation or environmental functions. Conclusion: These findings suggest that the function-specific nursing interventions for acute stroke patients need to be developed. Future research needs to test the usefulness of ICF items as an measurement tool.

• Interdisciplinary Bio Central
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• v.2 no.4
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• pp.13.1-13.8
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• 2010

The National BioResource Project of Japan is a governmental project to promote domestic/international research activities using biological resources. The project has 27 biological resources including three cereal resources. The core center and sub-center which historically collected the cereal resources were selected for each cereal program. These resources are categorized into several different types in the project; germplasm, genetic stocks, genome resources and database information. Contents of rice resources are wild species, local varieties in East and Southwest Asia & wild relatives, MNU-induced chemical mutant lines, marker tester lines, chromosome substitution lines and other experimental lines. Contents of wheat resources are wild strains, cultivated strains, experimental lines, rye wild and cultivated strains; EST clones and full-length cDNA clones. Contents of barley resources are cultivar and experimental lines, core collection, EST/cDNA clones, BAC clones, their filters and superpool DNA. Each resource is accessible from the online database to see the contents and information about the resources. Links to the genome information and genomic tools are also important function of each database. The major contents and some examples are presented here.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.1
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• pp.113-120
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• 2013

This paper proposes a design optimization approach for core of solenoid actuators by combining optimization techniques with the finite element method (FEM). A solenoid is an important element part which hydraulically controls a transmission system, etc. The demanded feature of the solenoid is that it performs an electromagnetic force output being constant regardless of the stroke and being proportional to coil current. The plunger compresses a spring with a minimum force of 12 N over an 1.7 mm travel. The orthogonal array, analysis of variance (ANOVA) techniques and response surface optimization, are employed to determine the main effects and their optimal design variables. The methodology is demonstrated as a optimization tool for the core design of a solenoid actuator.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.05b
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• pp.19-22
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• 2004

The resonant planar transformer, which had power capacity of 300 W, input voltage of 220 V, output voltage of 15 V, and switching frequency of 500 kHz, was designed and manufactured by using the planar core with large effective area and the flat copper lead frames for miniaturization and high efficiency of the switching mode power supply (SMPS). As well as, a resonant converter equipped with the above mentioned planar transformer was manufactured and electromagnetic characteristics were investigated. The numerical value of turns for 1st and 2nd winding were 12 and 2 respectively. The self inductance of 1st winding was 33.2 ${\mu}H$, very low leakage inductance of 1.27 ${\mu}H$, and the coupling factor of 0.98 were obtained at switching frequency of 300 kHz. The high efficiency of 88.21 % for the SMPS equipped with planar transformer was obtained at power capacity of 300 W.

• Journal of Electrical Engineering and Technology
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• v.12 no.1
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• pp.126-133
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• 2017

This paper deals with the effects of welding, which is done to fix the stator stack, on a motor in case of fabricating a prototype motor that is manufactured in a small quantity. In the case of a small motor, the stator is designed and fabricated with the segmented core as a way to raise the fill factor of winding wire to the utmost within a limited size. In case of fabrication by welding both inside and outside of the stator in order to fix the segmented-core stator, the effects of stack are ignored, and the eddy current loss occurs. This paper performed the no-load test on an IPM-type BLDC motor for driving the suction fan of a vacuum cleaner, which was manufactured by using a segmented-core stator. As a result of the test, it was found that input power more than expected was supplied. To analyze the effects of welding by using the finite element analysis method and verify them experimentally, a stator was re-manufactured by bonding, and input power supplied during the no-load test was compared.

• Journal of muscle and joint health
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• v.19 no.2
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• pp.107-119
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• 2012

Purpose: This study was conducted to extract international classification of functioning, disability, and health (ICF) core sets for measuring functional status in acute stroke patients, and to evaluate clinical applicability of the core sets. Methods: A set of 22 ICF items on functional status in acute stroke patients were extracted from the Korean general ICF core sets and ICF core sets for stroke patients. The extracted ICF functional items were assessed at the time of admission and discharge among 100 stroke patients who were admitted in a university hospital. Results: Comparing to functional status at admission of acute stroke patients, the overall functional status at discharge was improved. However, functions on defecation, skin protection, and relationship with immediate family at the time of discharge were not significantly changed. Conclusion: The set of ICF functional items identified in this study may be reliable and valid to assess acute stoke patients' body functions, activities and participation and environmental factors in the holistic and comprehensive nursing context. Nursing interventions on bowel elimination and skin protection for acute stroke patients need to be developed.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.191-191
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• 2006

The structures of the mesophases and their subunits of PS-b-P4VP in a toluene solution were studied by using SAXS, TEM and GIFT methods. The hierarchical structures of PS-b-P4VP, such as the individual micelle, the face-centered cubic (fcc) and body-centered cubic (bcc) structures and the lamellar structure, were identified for the first time. The diameter of the micelle core was ${\sim}80\;%$ of the most extended chain length of the core chain, suggesting that the core chains were quite stretched. The stretched chain in the core caused the core of the micelle to be not homogenous with a higher density at the center than at the outer part. As the concentration level increases, the fcc and both fcc and bcc appear for the packing of the micelles of PS(3.3k)-b-P4VP(4.7K) and PS(12K)-b-P4VP(11.8K), respectively. The lamellar structure was also identified, with a further increase in the concentration for PS(3.3k)-b-P4VP(4.7K). These hierarchical structures were also identified via TEM images.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.58.2-58.2
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• 2014

We present the results of the KVN observations of central galaxies in cool-core and non cool-core clusters. The goal is to study how cooling environments affect the AGN activities in the core where their host galaxies are embedded. From the HIghest FLUx Galaxy Cluster Sample (HIFLUGCS), we have selected 19 radio bright AGNs located in the center of clusters with various cooling timescale. In our pilot study, we have obtained 22 and 43 GHz fluxes and morphologies of the sample using the Korean VLBI network. We find that 22/43 GHz fluxes do not strongly depend on the presence of a cool gas flow. However, an intriguing fact is that most AGNs in the cool-core clusters show the hint of a pc-scale jet component while the ones in the non cool-core clusters do not. Based on these results, we discuss the role of cooling flows in the central cluster AGNs and their co-evolution.

• Journal of Engineering Education Research
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• v.23 no.4
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• pp.14-21
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• 2020

The aim of this study was to establish an university informal program roadmap, and also to draw up operational plans for human resources with core technologies of the fourth industry. To do this, first we derived university informal education program draft through experts workshop, then conducted a survey regarding the female university students' perception of educational programs and their educational needs on the 4th core technology matching programs. The following main results were obtained : First, students preferred 'hands-on training' by professionals and they wanted to be trained during summer or winter holidays or the night time during semesters. Also, they thought two hours of training per session was appropriate. Regarding these results, there was no difference depending on the majors. Second, while students had highly preferred for the courses related to data analysis, Arduino programing and VR(virtual reality), those related to 3D printing modeling were less preferred. Depending on the majors, preferred courses had different priorities, but non-preferred courses were similar regardless of majors. Based on these results, the university informal curriculum model and the operation plans for the core technologies of the fourth industry were proposed.