• Journal of Korean Neurosurgical Society
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• 제47권6호
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• pp.454-457
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• 2010

Pure ventral midline giant schwannoma is an extremely rare entity. Spinal intradural extramedullary schwannomas commonly occur posterolateral or anterolateral to the spinal cord. A case of a pure midline ventrally situated giant pan cervical extramedullary schwannoma in an 18-year-old male patient with compressive myelopathy and sphincter involvement is presented. Spinal MR imaging showed a midline ventrally situated extramedullary tumor with severe spinal cord compression extending from clivus to C7 vertebra. It was resected through a posterolateral approach. Histology was consistent with a schwannoma. Post operative MR imaging showed no evidence of the tumor. The radiological features, pathogenesis and surgical strategies in management of these difficult tumors are discussed and the relevant literature is briefly reviewed.

• The Korean Journal of Pain
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• 제10권2호
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• pp.304-307
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• 1997

Continuous epidural infusion, a combination of local anesthetic and opioid, have been widely administered for treatment of chronic cancer pain. A serious complications of epidural block is paraplegia which can also be caused by : direct spinal cord injury, epidural hematoma, epidural abscess, ischemic change, neurotoxicity, preexisting disease. Continuous epidural block for pain control of patient with cervical cancer was performed at $T_{12}/L_1$ interspace. A 4 cm catheter was inserted cephalad into the epidural space. After four months, back pain and motor weariless of lower extremities progressively developed. Spine CT showed bony destruction and soft mass-like lesion at $T_9$ & $T_{12}$ spine. We propose paraplegia was caused by spinal cord compression which resulted from vertebral metastasis of cervical cancer.

• 대한후두음성언어의학회지
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• 제26권2호
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• pp.141-143
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• 2015

Ortner's syndrome is a rare clinical entity with hoarseness attributable to recurrent laryngeal nerve palsy in cardiovascular diseases. The mechanism of this condition is thought to be due to compression of the recurrent laryngeal nerve by a dilated, tense cardiovascular structure against its adjacent tissue; thus, this is also known as cardio-vocal syndrome. We experienced the case of a 81-year-old female suffering from hoarseness due to a large aneurysm of the aortic arch, and reviews the literature for possible cardiovascular causes of Ortner's syndrome.

• 한국임상수의학회지
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• 제22권4호
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• pp.297-301
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• 2005

개에 실험적으로 후구마비를 유발한 후 감압술과 전침술을 병행 처치하였을 때 그 임상적 효과를 알아보고자 본 실험을 실시하였다. 3.15.0kg, 12년령의 신경계 질환이 없는 임상적으로 건강한 10두의 수캐를 각 5두씩 감압술 및 전침술 병용군 (A군)과 감압술 단독군 (B군)으로 편성하여 각 군의 실험견에 약 $40\%$의 척수압박을 하여 심부통각 지각이 있는 후구마비를 유발하였다. 후구마비 유발 48시간 후, 두 군 모두에 편측추궁절제술을 실시하고 압박물을 제거하였고, 감압술 및 전침술 병용군은 감압 이틀 후부터 회복시점까지 2일에 1회씩 전침 치료를 하였다. 실험기간 중, 매일 Talrov's grading system 변법을 사용하여 임상적 평가를 하였다. 실험전과 치료종료 시점의 체성감각유발전위(SEPs)를 측정하여 측정된 유발전위를 신경전도 속도로 환산하여 신경기능을 확인하였다. 감압술 및 전침술 병용군에서는 술후 보행능력 회복까지 $10.0\pm2.7$일이 걸렸으며, 완전회복까지는 $17.2\pm3.9$일이 소요되어 보행능력 회복에서 완전회복까지 $7.2\pm1.8$일의 재활기간이 필요하다. 한편 감압술 단독 적용군은 술 후 보행능력 회복까지 $13.4\pm3.7$일이 걸렸으며, 완전회복까지는 $34.2\pm14.5$일이 소요되어 보행능력 회복에서 완전회복까지 $20.8\pm11.8$일의 재활기간이 필요했다. 완전회복 후의 SEPs의 전도속도는 실험전의 정상범위로 회복된 양상을 보였다. 감압술 적용 후, 보행능력 획득까지의 기간은 두 군간에 유의적인 차가 없었으나, 완전회복 및 재활기간에 있어서는 감앗술과 전침 병용군이 더 짧은 치료기간을 보였다. 이상의 결과로 보아 개에서 추간판 탈출증에 의한 후구마비가 있는 경우, 감압술과 전침 치료를 병행하면 기능회복 기간을 단축시킬 수 있을 건으로 판단된다.

• Journal of Korean Neurosurgical Society
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• 제30권10호
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• pp.1241-1244
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• 2001

The authors report a very rare case of tuberculous spondylitis combined with a schwannoma of spinal cord. A 39- year-old man was admitted because of paraparesis(G1/G2). MRI showed severe cord compression at two different levels. One was by the bulged soft tissue and subligamentous abscess extending from T7 to T9 and the other was by an intradural extramedullary cord tumor at the level of T1-2. At first operation, T8 corpectomy and T7-9 plate fixation with autogenous iliac bone graft were performed. After then, Paraparesis was improved(G2/G3) postoperatively. The second operation underwent two weeks later. The tumor was totally removed and shortly after second operation, paraparesis was markedly improved(G3/G4). Histological diagnosis were tuberculous spondylitis and schwannoma, respectively. The authors reviewed this case where good surgical outcome was obtained by two stage operation.

• Journal of Korean Neurosurgical Society
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• 제51권4호
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• pp.191-198
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• 2012

Objective: Valproic acid (VPA), as known as histone deacetylase inhibitor, has neuroprotective effects. This study investigated the histological changes and functional recovery from spinal cord injury (SCI) associated with VPA treatment in a rat model. Methods: Locomotor function was assessed according to the Basso-Beatlie-Bresnahan scale for 2 weeks in rats after receiving twice daily intraperitoneal injections of 200 mg/kg VPA or the equivalent volume of normal saline for 7 days following SCI. The injured spinal cord was then examined histologically, including quantification of cavitation. Results: Basso-Beatlie-Bresnahan scale scores in rats receiving VPA were significantly higher than in the saline group (p<0.05). The cavity volume in the VPA group was Significantly reduced compared with the control (saline-injected) group (p<0.05). The level of histone acetylation recovered in the VPA group, while it was significantly decreased in the control rats (p<0.05). The macrophage level was significantly decreased in the VPA group (p<0.05). Conclusion: VPA influences the restoration of hyperacetylation and reduction of the inflammatory reaction resulting from SCI, and is effective for histology and motor function recovery.

• Elastomers and Composites
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• 제49권4호
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• pp.293-304
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• 2014

고무 공기 스프링(rubber air spring)은 자동차, 철도차량 등 수송기기의 서스펜션 장치로 사용되고 있다. 고무 공기 스프링은 고무 에어백의 압축과 팽창을 통한 탄성효과로 스프링의 역할을 한다. 고무 공기 스프링의 주요 구성요소 중 하나가 고무 슬리브(rubber sleeve)이다. 고무 슬리브는 주요 구성성분인 클로로프렌 고무와 나일론 6 코드 간의 접착이 매우 중요하다. 본 연구에서는 첨가제의 영향을 고려한 고무 슬리브의 최적 배합조성과 조건을 찾기 위해 다양한 물성시험을 하였다. 또한, 보강섬유의 최적 배향을 선정하기 위해 유한요소해석법을 이용한 수치해석을 수행하였다. 고무 공기 스프링을 제조하여 실제 차량에 장착하여 기초물성과 피로수명 및 기밀성을 시험하였다.

• Journal of Chest Surgery
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• 제28권9호
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• pp.872-875
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• 1995

Dumbbell neurogenic tumor is a rare disease, arising about 10 % of mediastinal neurogenic tumor. We report a 31 year old man who was suffered from paresthesia and weakness of lower extremities for about 8 months. Chest x-rays revealed a dumbbell shaped mass shadow in left lower posterior mediastinum. MRI demonstrated a well defined dumbbell shaped mass in the mediastinum of T7 level, including spinal cord compression by the extended tumor into the spinal canal and enlarged intervertebral foramen. The patient underwent one-stage combined resection of the tumor through the thoracotomy and laminectomy, simultaneously. The tumor was confirmed as neurilemmoma. The postoperative course was smooth and uneventful.

• The Korean Journal of Pain
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• 제22권3호
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• pp.249-252
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• 2009

Spinal epidural lipomatosis (SEL) is a rare condition of pathological overgrowth of fat tissue in the vertebral canal. SEL leads to back pain, radiculopathy or paraparesis. Glucocorticoids seem to play a major role in the development of SEL. SEL is best diagnosed by magnetic resonance imaging. The treatment of SEL is directed at reducing the body weight and decreasing the excess glucocorticoid. In severe cases, decompressive laminectomy with removal of the excess epidural fat might become necessary to alleviate the neurological symptoms caused by spinal cord compression.

• Journal of Korean Neurosurgical Society
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• 제54권1호
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• pp.61-64
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• 2013

As a cause of spinal cord compression, intramedullary spinal tuberculoma with central nervous system (CNS) involvement is rare. Aurthors report a 66-year-old female presented with multiple CNS tuberculomas including spinal intramedullary tuberculoma manifesting paraparesis and urinary dysfunction. We review the clinical menifestation and experiences of previous reported literature.