• Journal of Korean Neurosurgical Society
• /
• v.47 no.6
• /
• pp.454-457
• /
• 2010

Pure ventral midline giant schwannoma is an extremely rare entity. Spinal intradural extramedullary schwannomas commonly occur posterolateral or anterolateral to the spinal cord. A case of a pure midline ventrally situated giant pan cervical extramedullary schwannoma in an 18-year-old male patient with compressive myelopathy and sphincter involvement is presented. Spinal MR imaging showed a midline ventrally situated extramedullary tumor with severe spinal cord compression extending from clivus to C7 vertebra. It was resected through a posterolateral approach. Histology was consistent with a schwannoma. Post operative MR imaging showed no evidence of the tumor. The radiological features, pathogenesis and surgical strategies in management of these difficult tumors are discussed and the relevant literature is briefly reviewed.

• The Korean Journal of Pain
• /
• v.10 no.2
• /
• pp.304-307
• /
• 1997

Continuous epidural infusion, a combination of local anesthetic and opioid, have been widely administered for treatment of chronic cancer pain. A serious complications of epidural block is paraplegia which can also be caused by : direct spinal cord injury, epidural hematoma, epidural abscess, ischemic change, neurotoxicity, preexisting disease. Continuous epidural block for pain control of patient with cervical cancer was performed at $T_{12}/L_1$ interspace. A 4 cm catheter was inserted cephalad into the epidural space. After four months, back pain and motor weariless of lower extremities progressively developed. Spine CT showed bony destruction and soft mass-like lesion at $T_9$ & $T_{12}$ spine. We propose paraplegia was caused by spinal cord compression which resulted from vertebral metastasis of cervical cancer.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.26 no.2
• /
• pp.141-143
• /
• 2015

Ortner's syndrome is a rare clinical entity with hoarseness attributable to recurrent laryngeal nerve palsy in cardiovascular diseases. The mechanism of this condition is thought to be due to compression of the recurrent laryngeal nerve by a dilated, tense cardiovascular structure against its adjacent tissue; thus, this is also known as cardio-vocal syndrome. We experienced the case of a 81-year-old female suffering from hoarseness due to a large aneurysm of the aortic arch, and reviews the literature for possible cardiovascular causes of Ortner's syndrome.

• Journal of Veterinary Clinics
• /
• v.22 no.4
• /
• pp.297-301
• /
• 2005

This study was performed to evaluate the effects of the combination of electroacupuncture (EA) and surgical decompression on paraplegia due to spinal compression in dogs. Ten clinically healthy dogs were assigned into two groups (group A and group B). The one is for the combination of EA and surgical decompression, and the other is for surgical decompression alone. After decompression, neurological function was evaluated daily with modified Tarlov grading system. SEPs were measured as objective evaluation of normal spinal cord function before spinal compression and after neurological recovery. The period of rehabilitation in group A was significantly shorter than that in group B (p<0.05). Conduction velocity of SEPs showed a tendency to return to normal when the dogs got full recovery. According to these results, it was considered that the EA with surgical decompression was more effective than surgical decompression alone for paraplegia resulting from spinal cord injury in dog.

• Journal of Korean Neurosurgical Society
• /
• v.30 no.10
• /
• pp.1241-1244
• /
• 2001

The authors report a very rare case of tuberculous spondylitis combined with a schwannoma of spinal cord. A 39- year-old man was admitted because of paraparesis(G1/G2). MRI showed severe cord compression at two different levels. One was by the bulged soft tissue and subligamentous abscess extending from T7 to T9 and the other was by an intradural extramedullary cord tumor at the level of T1-2. At first operation, T8 corpectomy and T7-9 plate fixation with autogenous iliac bone graft were performed. After then, Paraparesis was improved(G2/G3) postoperatively. The second operation underwent two weeks later. The tumor was totally removed and shortly after second operation, paraparesis was markedly improved(G3/G4). Histological diagnosis were tuberculous spondylitis and schwannoma, respectively. The authors reviewed this case where good surgical outcome was obtained by two stage operation.

• Journal of Korean Neurosurgical Society
• /
• v.51 no.4
• /
• pp.191-198
• /
• 2012

Objective: Valproic acid (VPA), as known as histone deacetylase inhibitor, has neuroprotective effects. This study investigated the histological changes and functional recovery from spinal cord injury (SCI) associated with VPA treatment in a rat model. Methods: Locomotor function was assessed according to the Basso-Beatlie-Bresnahan scale for 2 weeks in rats after receiving twice daily intraperitoneal injections of 200 mg/kg VPA or the equivalent volume of normal saline for 7 days following SCI. The injured spinal cord was then examined histologically, including quantification of cavitation. Results: Basso-Beatlie-Bresnahan scale scores in rats receiving VPA were significantly higher than in the saline group (p<0.05). The cavity volume in the VPA group was Significantly reduced compared with the control (saline-injected) group (p<0.05). The level of histone acetylation recovered in the VPA group, while it was significantly decreased in the control rats (p<0.05). The macrophage level was significantly decreased in the VPA group (p<0.05). Conclusion: VPA influences the restoration of hyperacetylation and reduction of the inflammatory reaction resulting from SCI, and is effective for histology and motor function recovery.

• Elastomers and Composites
• /
• v.49 no.4
• /
• pp.293-304
• /
• 2014

Rubber air spring (RAS) is a special suspension device for the industries of automobile, railroad car and other transportation. A RAS serves as a spring component with the elastic effect of compression and expansion of air in a composite rubber bag. The main component of RAS is the rubber sleeve. Rubber sleeve is the composite which is made up of combination of chloroprene rubber (CR) and nylon 6 cord, and the adhesive strength between CR and nylon 6 cord is very important. In this study, considering the effects of additives in rubber sleeve, various physical properties were tested to find the optimal combination of composition and conditions. Further, in order to select the optimum orientation of the reinforcing fibers, numerical analysis was performed using the finite elements method. After assembling all components of RAS, it was mounted on an actual vehicle, and then it was tested air leakage, fatigue life and fundamental properties.

• Journal of Chest Surgery
• /
• v.28 no.9
• /
• pp.872-875
• /
• 1995

Dumbbell neurogenic tumor is a rare disease, arising about 10 % of mediastinal neurogenic tumor. We report a 31 year old man who was suffered from paresthesia and weakness of lower extremities for about 8 months. Chest x-rays revealed a dumbbell shaped mass shadow in left lower posterior mediastinum. MRI demonstrated a well defined dumbbell shaped mass in the mediastinum of T7 level, including spinal cord compression by the extended tumor into the spinal canal and enlarged intervertebral foramen. The patient underwent one-stage combined resection of the tumor through the thoracotomy and laminectomy, simultaneously. The tumor was confirmed as neurilemmoma. The postoperative course was smooth and uneventful.

• The Korean Journal of Pain
• /
• v.22 no.3
• /
• pp.249-252
• /
• 2009

Spinal epidural lipomatosis (SEL) is a rare condition of pathological overgrowth of fat tissue in the vertebral canal. SEL leads to back pain, radiculopathy or paraparesis. Glucocorticoids seem to play a major role in the development of SEL. SEL is best diagnosed by magnetic resonance imaging. The treatment of SEL is directed at reducing the body weight and decreasing the excess glucocorticoid. In severe cases, decompressive laminectomy with removal of the excess epidural fat might become necessary to alleviate the neurological symptoms caused by spinal cord compression.

• Journal of Korean Neurosurgical Society
• /
• v.54 no.1
• /
• pp.61-64
• /
• 2013

As a cause of spinal cord compression, intramedullary spinal tuberculoma with central nervous system (CNS) involvement is rare. Aurthors report a 66-year-old female presented with multiple CNS tuberculomas including spinal intramedullary tuberculoma manifesting paraparesis and urinary dysfunction. We review the clinical menifestation and experiences of previous reported literature.