• Toxicological Research
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• 제17권2호
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• pp.97-106
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• 2001

Korean ginseng products have been fumigated with ethylene oxide (EO) for sterilization and prolongation of storage periods. However, there had been controversies indicating that the consumption of food treated with EO might cause harmful effects in human. Since, in Korea the use of EO gas for food treatment was banned in 1991. Since then, irradiation technique has been developed as an alternative. This study was carried out to investigate the effects of irradiated ginseng on fertility, and reproductive and developmental toxicity. Either EO gas fumigated or gamma-irradiated ginseng was administered to male rats by oral gavage for 63 days during the premating period. Female rats were administered from 14 days before mating to day 20 of gestation or to day 21 of lactation. The exposure amount of irradiation used was 5, 10 and 30 kGy, respectively. There were no treatment related changes of darns in clinical signs, and parturition. No treatment related changes in food consumption, body/organ weights, male/female reproductive and fertility performances were observed. F1 fetuses showed no external abnormality. Reflex/sensory junctions, physical/behavioral development, and reproductive performance of F1 rats were not adversary affected. The results of this study show that gamma-irradiated ginseng, up to 30 kGy, has no adverse effects on the fertility, reproduction and development in Wistar rats.

• Annals of Clinical Neurophysiology
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• 제10권1호
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• pp.29-32
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• 2008

Although various criteria on the diagnosis of diabetic neuropathy are applied from trial to trial, being tailored in concert with its purpose, the utmost evidences of the diagnosis are subjective symptoms and objective signs of neurologic deficit. The application and interpretation of auxiliary electrophysiological test including nerve conduction study (NCS) should be made on the context of clinical pictures. The evaluation of the functions of small, thinly myelinated or unmyelinated nerve fibers has been increasingly stressed recently with the advent of newer techniques, e.g., measurement of intraepidermal fiber density, quantitative sensory testing, and autonomic function test. And the studies with those techniques have shed light to the nature of the evolution of diabetic neuropathy. The practical application of these techniques to the diagnosis of diabetic neuropathy in the individual patients, however, should be made cautiously due to several shortcomings: limited accessibility, wide overlapping zone between norm and abnormality with resultant unsatisfactory sensitivity and specificity, difficulty in performing subsequent tests, unproven quantitative correlation with clinical deficit, and invasiveness of some technique. NCS, as an extension of clinical examination, is still the most reliable electrophysiological test in evaluating neuropathy and gives the invaluable information about the nature of neuropathy, whereas the newer techniques need more refinement of the procedure and interpretation, and the accumulation of large scaled data of application to be considered as established diagnostic tools of peripheral neuropathy.

• 대한임상검사과학회지
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• 제39권3호
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• pp.223-230
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• 2007

Several methods have been used in the detection of Helicobacter pylori (H. pylori) which was believed to be a pathogenic organism causing chronic gastritis, benign peptic ulcer, gastric carcinoma or malignant lymphoma. Even though several methods were introduced for detection of H. pylori in stomach, there were controversies in their sensitivities and specificities. This experiment were designed to study the comparative analysis of staining methods (hematoxylin and eosin (H&E), Giemsa, Warthin-Starry and immunohistochemical stain) to dectect H. pylori in the gastric mucosa. The results were as follows. Average density score of H. pylori classified by Genta were 2.29 in Warthin-Starry stain, 2.19 in Giemsa stain, 1.34 in immunohistochemical stain and 0.98 in H&E stain. By comparison between inflammatory degree by Sydney system and result of Warthin-Starry stain, the detection rate and densities of H. pylori were increased from mild (61.5% and 0.8), moderate (90.4 and 2.1), and severe (100% and 3.2). From the above findings, Warthin-Starry stain is useful method for detection of H. pylori in gastric mucosa.

• 대한한의학회지
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• 제24권4호
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• pp.113-119
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• 2003

The association between apolipoprotein E (apo E) gene polymorphism and ischemic cerebrovascular disease (ICVD) has been controversial. These controversies may be due to inaccurate classification of patients and ethnic differences. We investigated the association between apo E genotypes and ICVD patients by case-control study in a Korean population. The association between apo E polymorphism and ICVD was examined in 121 patients with ICVD and 132 controls without ICVD. The E3/E4 phenotype was more frequent in control subjects (23.8％) than in patients (13.0％) (p<0.05). The E2/E3 phenotype was more frequent in patients (14.8％) than in control subjects (10.8％), but the difference was not statistically significant (p>0.05). These results suggest that the E4 allele may be a protective factor against early vascular morbidity, and the E2 allele may be a risk factor for cerebrovascular morbidity.

• Architectural research
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• 제19권3호
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• pp.53-61
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• 2017

This study aims to understand and analyze the social recognition and debate shown during the progress of the Asian Culture Complex (ACC) public project as well as the environmental evaluation performed by provincial community members. A 30-question survey based on a Likert scale was conducted with 150 experts. The study showed, first, that despite controversies over landmarks and historical locations, the quality of the architect's first draft was considered fairly high. However, vibrant landmarks were greatly desired. Furthermore, respondents reported conflicting recognitions of the same concept, which were defined differently depending on the terms and concepts used by the architect. Second, historical locations were considered important. The architects' final design was modified based on quality and in response to social pressure, resulting in the partial retention of the provincial government annex building. Although the first draft was considered to be of high quality, the modified plan was considered even better than the original design, revealing the 2-fold characteristics of the identical phenomenon in the environmental evaluation. Third, many groups held opinions that were balanced between the architects' originality and the value of community-based recognition; hence, the social inclination and evaluation of the project differed across the public.

• 한국조경학회지
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• 제26권2호
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• pp.143-154
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• 1998

This study was carried out to investigate and analyze the waterscape of the Sunam Temple on Mt. Chokye over which controversies had been actively raised, especialy of its Japanese impacts, comparing the phenomena arising from it with those of Korean and Japanese traditional temples. And then the identity of the Sunam Temple was clarified in itself. It is concentrated on what exotic formation are found in waterscapes of the Sunam Temple and how they can be proved via what factors. The obtained results were as follows : 1. Two curved ponds located in the western part of the Iljumun gate have a specific features not visible in any other Korean traditional temples, serving as an object of interest. Such ponds with curved form in the Sunam Temple had an affinity to those of stroll-style garden in Kyoto area. 2. The winding waterway along with curved ponds in the west of the Iljumun gate was introduced into the Sunam Temple. Therby, it was an exceptional phenoma hardely found in the traditional temples of Korea. This study was a typical one, as found in the stroll Japanese temples. Especially, the swinding waterway found in both the Kinkakuji Temple and the Ginkakuji Temple designated as object temples of comparison in the present study.

• Journal of Plant Biology
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• 제8권1_2호
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• pp.11-18
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• 1965

Since Taquet's first discovery of wild P. yedoensis at Mt. Halla, Korea, in 1908, its morphological chracteristics and question of origin of cultivated yedoensis have given controversies to the botanists. Takenaka, through his experiments on the hybridity of cultivated P. yedoensis, recently holds the opinion that P. yedoensis might have originated in Izu peninsula, Japan. The author presents the summarized report on the wild P. yedoensis and its putative parents based on his 2 years' investigated carried out at Mt. Halla during his breeding experiment of genus Prunus. The species of cherry tree used in the present investigation were identified by Prof. Mankyu Park and Mr. Jonghyu Pu, Korean taxonomists. 1) Wild cherry trees which grow wild in Mt. Halla and whose blooming season is April are mostly P. subhirtella var. pendula form. ascendens and P. donarium P. yedoensis is rare in number, around 10 individuals, having been found in a half century. 2) Individuals of wild yedoensis are variable in some of their morphological characteristics. This is, also, true in other species of Prunus. 3) Wild yedoensis whose vigorous growth, sterility, and rarity in number suggest hybrid origin, has intermediate characteristics between the P. subhirtella and P. donarium. 4) Due to the abnormal weather of the island and various environmental factors such as havbitats, some of the early-blooming subhirtella and late-blooming donarium would bloom at the same time, giving these two species the changes to cross. 5) Wild yedoensis is slightly different in some of its quantitative characters from cultivated species.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제41권
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• pp.8.1-8.6
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• 2019

Background: Resorbable devices have recently been adopted in the field of orthognathic surgery with controversies about their postoperative skeletal stability. Hence, we determined the long-term skeletal stability of unsintered hydroxyapatite/poly-ʟ-lactic acid (HA/PLLA) mesh for osteofixation of mandibular sagittal split ramus osteotomy (SSRO), and compared it with that of titanium miniplate. Methods: Patients were divided into resorbable mesh and titanium miniplate fixation groups. A comparative study of the change in the mandibular position was performed with preoperative, 1-day, 6-month, and 2-year postoperative lateral cephalograms. Results: At postoperative 6 months-compared with postoperative 1 day, point B (supra-mentale) was significantly displaced anteriorly in the titanium-fixation group. Moreover, at postoperative 2 years-compared with postoperative 6 months, point B was significantly displaced inferiorly in the titanium-fixation. However, the HA/PLLA mesh-fixation group did not show any significant change with respect to point B postoperatively. Conclusions: The HA/PLLA mesh-fixation group demonstrated superior long-term skeletal stability with respect to the position of mandible, when compared with the titanium-fixation group.

• 한국중재학회지:중재연구
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• 제18권3호
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• pp.51-69
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• 2008

The financial industry in which arbitration is most frequently resorted to so as to resolve disputes is the sector related to the securities industry. Most securities related disputes are raised from broker-dealer controversies which is not new in the Republic of Korea. The disputes between securities brokers and customers are very frequently settled by arbitration in the United States. But the arbitration in the securities area may deprive investors from securities regulation's protection. Introducing the United States' Federal Supreme Courts cases, the author explores the logic of how the pre-dispute arbitration agreement compatible with Securities regulations. However, the author insist the South Korea should more careful in accepting pre-dispute arbitration contract in securities area. Mostly because of the lack of more specific way to secure substantive fairness in securities arbitration. Also the author worries about the possibility of prevailing pre-dispute arbitration agreement in all of the securities investment contract without any other choices, or securities laws' protection. But the author also suggests to introduce public securities arbitration system of the States, and also insists the way to secure substantive fairness, or the application of securities regulations in securities arbitrations. Which may be the pre-requirements for the pre-dispute arbitration agreement in securities investment contract.

• 한국중재학회지:중재연구
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• 제21권1호
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• pp.157-181
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• 2011

The term of defense procurement is used indifferently from defence acquisition. It consists of two sectors : domestic defense procurement and foreign defense procurement. For efficient and transparent defense procurement, Defence Acquisition Program Law in Korea suggests some principles including the purchase of domestically manufactured munitions in the first instance, and the Defense Acquisition Program Administration(DAPA)'s direct procurement of munitions, etc. By reviewing the characteristics, process, current situation and model contracts of defense procurement, it is found that domestic procurement contracts only propose the legal approach instead of arbitration and foreign procurement contracts suggest confusedly both the legal approach and arbitration for amicable disputes settlement. Therefore, it is quite recommended for arbitration organizations such as the Korean Commercial Arbitration Board(KCAB), the Korean Arbitrators Association(KAA), and the Korean Association of Arbitration Studies(KAAS) to foster a variety of strong awareness campaign, education and consulting programs, etc. for the popular use of arbitration clause. It will contribute to settle any disputes and controversies between the parties more speedy, economically and rationally, thereby reducing the costs, time and pains for solving them.