• Title/Summary/Keyword: Controlled Type

Search Result 2,429, Processing Time 0.033 seconds

Controlled Release of Propranolol.HCI from Hollow Type Suppositories Inserted Polyvinyl Alcohol Hydrogel Capsule (폴리비닐알코올 하이드로겔 캅셀을 삽입한 중공좌제로부터 염산프로프라놀롤의 조절 방출)

  • 진선경;문이렌;구영순
    • YAKHAK HOEJI
    • /
    • v.43 no.2
    • /
    • pp.150-159
    • /
    • 1999
  • Hollow type suppositories inserted polyvinyl alcohol (PVA) hydrogel capsule containing propranolol·HCI (PPH) were prepared using different bases, polyethylene glycol (PEG), Witepsol H-15 (WH-15) and Witepsol W-35 (WW-35) to improve the controlled release of PPH. The release of PPH from the hollow type suppository inserted PVA hydrogel capsule was retarded than that from PEG, WH-15, or WW-35 hollow type suppositories in rat rectal cavity. When the suppositories were administered to rats, the controlled release of PPH was proved by the plasma concentration-time-profiles of PPH. No significant difference (p〈0.05) among the three different hollow type suppositories was observed in terms of AUC and MRT of PPH. WH-15 hollow type suppository inserted 12% of PVA hydrogel capsule caused irritation to rat rectal mucosa. However, the WH-15 hollow type suppository inserted PVA hydrogel capsule caused no severe irritation on rectal mucosa. The application of the hollow type suppositories using PVA in sustained rectal delivery of drugs might be feasible.

  • PDF

Control-performance Improvement of Dual EHAs (이중 EHA의 제어 특성 개선)

  • Lee, Seong Ryeol;Hong, Yeh Sun
    • Journal of Drive and Control
    • /
    • v.13 no.3
    • /
    • pp.32-38
    • /
    • 2016
  • For this paper, the position-control performances of dual EHA(electro-hydrostatic actuator) systems were investigated according to two cases wherein the double-rod- and single-rod-type hydraulic cylinders were combined. Since the control performance is significantly dependent on the load conditions including external forces such as the inertia load, it is proposed here that the two sub-EHAs are driven by separate position and force controllers, instead of two identical position controllers. According to the simulation results, the best performance was achieved by the position-controlled single-rod-type EHA that was combined with a force-controlled double-rod-type EHA. As the force-controlled double-rod-type EHA compensated for the external loads on the position-controlled single-rod-type EHA, the position-control performance was not influenced by external forces including the inertia load. In addition, the position-controlled single-rod-type EHA contributed to the enhancement of the damping ratio by absorbing the pressure peaks through its internal accumulator. Due to the symmetrical piston areas, the double-rod-type EHA is more suitable for force control than the single-rod- type EHA.

Formulation and Evaluation of Controlled Release Patch Containing Naproxen (나프록센 함유 방출제어형 패취의 제제설계 및 평가)

  • Rhee, Gye-Ju;Hong, Seok-Cheon;Hwang, Sung-Joo
    • Journal of Pharmaceutical Investigation
    • /
    • v.29 no.4
    • /
    • pp.343-348
    • /
    • 1999
  • The purpose of this study is to prepare the controlled release adhesive patch containing naproxen. Pressuresensitive adhesive (PSA)-type patch was fabricated by casting of polyisobutylene (PIE.) and mineral oil in toluene. Membrane-controlled release (MCR)-type patch was prepared by the attachment of the controlled release membrane on the PSAtype patch. The membrane was mainly composed of Eudragit, polyethylene glycol(PEG) and glycerin. The drug release profile and skin permeation test with various patches were evaluated in vitro. The release of naproxen from PIE-based PSAtype patch with various loading doses fitted Higuchi's diffusion equation. However, the permeation of naproxen through hairless mouse skin from PSA-type patch followed zero-order kinetics. In MCR-type patch, thickness of controlled release membrane affected on the drug release rate highly. In the composition of membrane, the release rate was decreased as the ratio of Eudragit increased. The drug release from the MCR-type patch followed zero order kinetics. The permeation of naproxen through hairless mouse skin from MCR-type patch showed lag time for the intial release period and didn't fit the zero-order kinetics

  • PDF

DOUBLE CONTROLLED CONE METRIC SPACES AND THE RELATED FIXED POINT THEOREMS

  • Tayebeh Lal Shateri
    • The Pure and Applied Mathematics
    • /
    • v.30 no.1
    • /
    • pp.1-13
    • /
    • 2023
  • In this paper, we introduce double controlled cone metric spaces via two control functions. An example of a double controlled cone metric space by two incomparable functions, which is not a controlled metric space, is given. We also provide some fixed point results involving Banach type and Kannan type contractions in the setting of double controlled cone metric spaces.

An Experimental Study to Improve the Characteristics of Electrode Type Humidifier (전극형 가습기의 특성을 개선하기 위한 실험적인 연구)

  • Park, Kyu-Hong;Song, Ha-Jin;Byun, Jae-Young
    • The Transactions of the Korean Institute of Electrical Engineers P
    • /
    • v.58 no.3
    • /
    • pp.310-315
    • /
    • 2009
  • This investigation was performed to study the characteristics of electricity and heat transfer that occur in the cylinder of electrode type humidifier during the process of water evaporation. Measurements were made to obtain the amount of water evaporation, the consumption of electric power, electrical conductivity, etc according to the materials and shapes of electrode. When the humidifier was in non-drain controlled mode, the number and amplitude of current cycle per minute increased gradually with the lapse of time, whereas for drain controlled mode, it decreased about 40[%] after draining water. It was found that for non-drain controlled mode, the thermal efficiency of humidifier which used SS400, STS316 and wire net electrode type was about 95~96[%] and it was 2~4[%] higher than that of drain controlled mode. Also, it was shown that the thermal efficiency of humidifier which used neighboring six-phase electrode balanced electrically was 4[%] higher than that of existing six-phase type.

Large viewing angle walk through type display using smoke screen

  • Sato, Koki;Takano, Kunihiko;Ohki, Makoto
    • Proceedings of the Korean Society of Broadcast Engineers Conference
    • /
    • 2009.01a
    • /
    • pp.790-793
    • /
    • 2009
  • In the case of projection type display, it needs to use the screen in order to project the image clearly and wide viewing angle. We have been developing the step in type display system using the smoke screen. However, the image with smoke screen was flickered by gravity and air flow. Then we considered to reduce the flicker of the image and we found that flicker can be reduced and viewing angle becomes more large. This time we report the large viewing angle step in type display system using screen made up with very small particle size smoke and flow controlled nozzle. Hence, at first we considered the most suitable particle for the screen and then the shape of screen and then we constructed the array of flow controlled smoke screen. By the results of experiment we could get considerably high contrast flicker-less image and get the viewing angle more than $60^{\circ}$ by this flow controlled nozzle attached new type smoke screen and make clear the efficiency of this method.

  • PDF

The analysis of dynamic behavior for horizontal drum type HRSG (Horizontal drum type HRSG(Heat Recovery Steam Generator)의 동특성 해석)

  • Lee, Chi-Hwan;Kim, Sung-Ho;Kim, Jong-Hyun
    • Proceedings of the KSME Conference
    • /
    • 2000.11b
    • /
    • pp.645-650
    • /
    • 2000
  • This dynamic analysis is performed about shutdown, load controlled and temperature controlled startup operating characteristics of the Horizontal drum type HRSG. This analysis was performed by constructing a dynamic model of the plant and running it through the appropriate.

  • PDF

Voltage control of three phase rectifier with current-controlled voltage type converter

  • Woo, Myeong-Ho;Jeong, Seung-Gi
    • Proceedings of the KIEE Conference
    • /
    • 1991.11a
    • /
    • pp.207-209
    • /
    • 1991
  • This paper deals with voltage control method of PWM rectifier using current-controlled voltage type converter. A linearized model of the current-controlled rectifier is derived, which is used to examine the effect of controller gains to its dynamic responses. Through the simulation, it is shown that the proposed model is generally valid, which is confirmed by experimental results.

  • PDF

Current-Mode Electronically Tunable Universal Filter Using Only Plus-Type Current Controlled Conveyors and Grounded Capacitors

  • Minaei, Shahram;Turkoz, Sait
    • ETRI Journal
    • /
    • v.26 no.4
    • /
    • pp.292-296
    • /
    • 2004
  • In this paper we present a new current-mode electronically tunable universal filter using only plus-type current controlled conveyors (CCCII+s) and grounded capacitors. The proposed circuit can simultaneously realize lowpass, bandpass, and highpass filter functions - all at high impedance outputs. The realization of a notch response does not require additional active elements. The circuit enjoys an independent current control of parameters $\omega_0$ and $\omega_0/Q$. No element matching conditions are imposed. Both its active and passive sensitivities are low.

  • PDF

Capacity Modulation of a Multi-Type Heat Pump System Using PID Control (PID 제어를 이용한 멀티형 열펌프의 용량조절)

  • 정대성;김민성;김민수;이원용
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
    • /
    • v.12 no.5
    • /
    • pp.446-475
    • /
    • 2000
  • Performance of a water-to-water multi-type heat pump system using R22 has been experimentally investigated. Total refrigerant flow rate was adjusted with a variable speed compressor and the refrigerant flow rate for two indoor units were controlled by electronic expansion valves. Evaporator outlet pressure of refrigerant and indoor unit outlet temperatures of secondary fluid were selected as controlled variables. Experiments were carried out for both cooling and heating modes using PID control method. Results show that the multi-type heat pump system can be adequately controlled by keeping control gains at certain levels for various operating conditions.

  • PDF