• Analytical Science and Technology
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• v.16 no.6
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• pp.488-498
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• 2003

By LC/MS/MS, the analytical method of sildenafil and its analogues (homosildenafil, vardenafil and tadalafil) used as used medical treatment of impotence was established. electrosprary ionization (ESI) and atmospheric pressure chemical ionization (APCI) as a ionization method were applied. Several parameter were varied and the sensitivity and reproducibility were compared. In LC/ESI-MS method, capillary voltage, cone voltage, extractor, entrance and RF lens to create appropriate productr ions for multiple reaction monitoring (MRM) were variable parameter, but the formation of the other product ions except the precursor ion could not detect. And the value of entrance, collision energy, exit, corona voltage, cone voltage, extractor, RF lens, cone gas, and desolvation gas in APCI mode were varied, only the creation pattern of fragment ions by the change of RF lens value were detected, and the limit of detection was decreased due to the increase of S/N. Ten millimole ammonium formate (pH 4.8):acetonitrile=70:30 by isocratic elution in HPLC system was shown the maximum sensitivity in MS, the detection limit of sildenafil, homosildenafil, vardenafil and tadalafil obtained by ESI-MRM were 0.10, 0.025, 0.025, and $0.25{\mu}g/mL$ at S/N>5, respectively.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.336-336
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• 2000

This paper studied on the yaw motion of the gantry crane which is used for the automated container terminal. Though several problems are occurred in driving of gantry crane, they are solved by the motion by the operator. But if the gantry crane is unmanned, it is automatically controlled without any human operation. There are two types, cone and flat typo in driving wheel shape. In cone type, lateral vibration and yaw motion of crane are issued. To bring a solution to these problems, the dynamic equation of the gantry crane driving mechanism is derived and it used PD(Proportional-Derivative) controller to control the lateral vibration. The simulation result of the driving mechanism using the Runge-Kutta method is presented in this paper.

• Journal of the Korean Geotechnical Society
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• v.38 no.11
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• pp.55-67
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• 2022

This study applied the dynamic cone penetrometer test (DCPT) and light-weight deflectometer test (LWDT) to the quality control of subgrade base by performing DCPT, LWDT, and plate load test (PLT) at two earthwork sites. Although DCPT and LWDT were performed under the same conditions, the results showed significant variation with the test location. Because the measured value at the time of the initial blow, which varies depending on the test location, significantly influenced the test result. Thus, it was appropriate to ignore the first two blows as preliminary blows and use subsequent measurements as quality control indicators. In addition, DCPT, LWDT, and PLT results showed a high correlation under the same conditions. Especially regression analyses using averaged data for each experiment condition tended to yield significantly improved R² values over individual point data sets. This indicates that average DCPT and LWDT values at various adjacent locations are better quality control indicators for subgrade bases than individual point values.

• Journal of Biosystems Engineering
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• v.40 no.3
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• pp.165-177
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• 2015

Purpose: Accurate monitoring of soil strength is a key technology applicable to various precision agricultural practices. Soil strength has been traditionally measured using a cone penetrometer, which is time-consuming and expensive, making it difficult to obtain the spatial data required for precision agriculture. To improve the current, inefficient method of measuring soil strength, our objective was to develop and evaluate an in-situ system that could measure horizontal soil strength in real-time, while moving across a soil bin. Methods: Multiple cone-shape penetrometers were horizontally assembled at the front of a vertical plow blade at intervals of 5 cm. Each penetrometer was directly connected to a load cell, which measured loads of 0-2.54 kN. In order to process the digital signals from every individual transducer concurrently, a microcontroller was embedded into the measurement system. Wireless data communication was used between a data storage device and this real-time horizontal soil strength (RHSS) measurement system travelling at 0.5 m/s through an indoor experimental soil bin. The horizontal soil strength index (HSSI) measured by the developed system was compared with the cone index (CI) measured by a traditional cone penetrometer. Results: The coefficient of determination between the CI and the HSSI at depths of 5 cm and 10 cm ($r^2=0.67$ and 0.88, respectively) were relatively less than those measured below 20 cm ($r^2{\geq}0.93$). Additionally, the measured HSSIs were typically greater than the CIs for a given numbers of compactor operations. For an all-depth regression, the coefficient of determination was 0.94, with a RMSE of 0.23. Conclusions: A HSSI measurement system was evaluated in comparison with the conventional soil strength measurement system, CI. Further study is needed, in the form of field tests, on this real-time measurement and control system, which would be applied to precision agriculture.

• Journal of Forest and Environmental Science
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• v.37 no.4
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• pp.309-314
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• 2021

This study aimed to enhance seed productivity and secure genetic resources for Pinus densiflora for. multicaulis. We analyzed the characteristics of cone and seed generated by control pollination between Pinus densiflora (PD) and Pinus densiflora for. multicaulis (PDM). The highest number of cone scales (63.0) was obtained from the self-pollinated (sp) PDM clone B (PDM-sp-B), whereas the lowest number of cone scales (44.7) was obtained from two combinations designated as PDM-A×PD-075 and PDM-A×PD-0111. Both female parents of the hybrids were PDM-A. The highest seed production capacity (80.8) was obtained from the open-pollinated (op) PDM clone B (PDM-op-B). The seed potentials of PDM-B×PD-0111, PDM-op-A, and PDM-sp-B were 67.4, 66.5, and 63.1, respectively. The highest number of fertile scales (41.5) was obtained from PDM-op-B, and the lowest number of fertile scales (28.8) was obtained from PDM-A×PD-075. The total number of aborted ovules and 1st aborted ovules was not statistically significant in the mating design. The cross combination of PDM-B×PD-0111 had the highest number (34.8) of filled seeds and the lowest number of 2nd aborted ovules (5.2) and empty seeds (9). PDM-op-B had the highest number of developed seeds (47.6), although the number of empty seeds was the highest (41.2). Therefore, we conclude that the mating design of PDM-B×PD-0111 is useful for future breeding programs to improve seed yield of PDM. Our results showed that there was a strong correlation between the following two parameter pairs: number of scales and number of fertile scales, and the number of fertility scales and seeds potential (r=0.89 and r=0.84, respectively; both p<0.01).

• Imaging Science in Dentistry
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• v.46 no.1
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• pp.9-16
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• 2016

Purpose: To evaluate the upper airway dimensions of obstructive sleep apnea (OSA) and control subjects using a cone-beam computed tomography (CBCT) unit commonly applied in clinical practice in order to assess airway dimensions in the same fashion as that routinely employed in a clinical setting. Materials and Methods: This was a retrospective analysis utilizing existing CBCT scans to evaluate the dimensions of the upper airway in OSA and control subjects. The CBCT data of sixteen OSA and sixteen control subjects were compared. The average area, average volume, total volume, and total length of the upper airway were computed. Width and anterior-posterior (AP) measurements were obtained on the smallest axial slice. Results: OSA subjects had a significantly smaller average airway area, average airway volume, total airway volume, and mean airway width. OSA subjects had a significantly larger airway length measurement. The mean A-P distance was not significantly different between groups. Conclusion: OSA subjects have a smaller upper airway compared to controls with the exception of airway length. The lack of a significant difference in the mean A-P distance may indicate that patient position during imaging (upright vs. supine) can affect this measurement. Comparison of this study with a future prospective study design will allow for validation of these results.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.10a
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• pp.725-728
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• 2002

In this Paper, a mathematical model describing the dynamics of pilot operated pressure control valve was derived. A attempt to analyze the Parameters(seat diameter, cone angle, spring stiffness, control volume) which relate to the performance of the object valve was carried out. Simulation using AMESim as a simulation tool was operated, and verified the validity of our simulation by means of comparison our simulation results with an experimental results of the pilot operated pressure control valve.

• Korean Journal of Plant Resources
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• v.29 no.2
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• pp.163-170
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• 2016

Antioxidant activity and inhibitory effect on oxidative DNA damage of ethyl acetate fractions extracted from Cone of Red Pine (Pinus densiflora) were investigated to find utilization of Cone, by-product of Red Pine, thrown out after berry shatter, as a new natural plant resource. Cone from P. densiflora was extracted with methanol (MeOH) and separated to petroleum ether, ethyl acetate and water fraction. Among them, ethyl acetate fraction was used. The antioxidant activity was conducted by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical, 2, 2'-Azino-bis (3-ethylbenzothiazoline-6 sulfonic acid) diammonium salt (ABTS) radical scavenging assay, Fe²⁺ chelating assay and reducing power assay. The inhibitory effect on oxidative DNA damage was determined by DNA cleavage assay using φX-174 RF I plasmid. The results of DPPH and ABTS radical scavenging activity at 200 ㎍/㎖ of extracts were 86.50% and 95.80% respectively, which were similar figures compared with L-ascorbic acid as control. Fe²⁺ chelating activity was 77.96% and reducing power was 0.77 at 200 ㎍/㎖. Total phenolic component was 27.29±0.3 ㎎/g and Vitamin C content was 1.84±0.1 ㎎/g. Also ethyl acetate fraction from Cone has inhibitory effect, using φX-174 RF I plasmid on DNA cleavage assay. In conclusion, Cone, by-product of P. densiflora, showed high antioxidant activity and inhibitory effect on oxidative DNA damage. Therefore this study suggests Cone, useless by-product, can be developed as a new natural plant resource with lots of utilization such as an effective antioxidant, natural medicine, food, cosmetics and so on.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2000.11a
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• pp.185-195
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• 2000

This pacer studied on the lateral motion and yaw motion of the gantry crane which is used for the automated container terminal with two driving wheel types. Though several problems are occcurred in driving of gantry crane, they are solved by the motion by the operators. But, if the gantry crane is unmanned, it is automatically controlled without any operation. There are two types, cone and flat t y pin driving wheel shape. In cone type, lateral vibration and yaw motion of crane are issued. In flat type, the collision between wheel-flange and rail or the fitting between wheel-flanges and rail is issued. Especially, the collision between wheel-flange and rail is a very critical problem in driving of unmanned gantry crane. To bring a solution to the problems, the lateral and yaw dynamic equations of the driving mechanism of gantry crane with two driving wheel types are derived. Then, we investigate the driving characteristics of gantry crane. And this study used PD(Proportional-Derivative) Controller to control the lateral displacement and yaw angle of the gantry crane. The simulation result of the driving mechanism using the Runge-Kutta Method is presented in this paper.

• Proceedings of the Korean Geotechical Society Conference
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• 2004.03b
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• pp.910-921
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• 2004

In this study, the pilot tests on the reclaimed land were performed in order to find the suitable construction method with dynamic compaction Type I, Type II at different dynamic energy and hydraulic hammer compaction. The estimation of the compaction through the various pilot tests was performed by the CPT-qc, SPT-N and field density tests. As the result of the pilot tests, it shows that the dynamic compaction method is better than the hydraulic hammer compaction method in the effect of the ground improvement, especially dynamic compaction Type I is much superior to others. When it comes to method for measuring the intensity of the ground, the value of the cone penetration test-resistance(qc) is much suitable for the ground. Besides, the standards for the compaction control, which showed that over 10Mpa at 0 through 5meters in the upper layer and 7Mpa at 5 through 8meters in the lower layer in the CPT-qc, could be found without discrimination of the upper road and lower road on the reclaimed land. And it also found that the intensity of the reclaimed land gets back to the original status in about 10 through 15 days.