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Hyperfractionated Radiotherapy with Concomitant Boost Technique for Unresectable Non-Small Cell Carcinoma of the Lung (절제 불가능한 비소세포 폐암의 다분할조사 방사선 치료)

  • Chun, Ha-Chung;Lee, Myung-Za
    • Radiation Oncology Journal
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    • v.9 no.2
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    • pp.221-225
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    • 1991
  • Twenty five patients with unresectable non-small cell carcinoma of the lung have been treated with hyperfractionated radiotherapy with concomitant boost technique since September, 1989. Those patients with history of previous surgery or chemotherapy, pleural effusion or significant weight loss (greater than $10\%$ of body weight) were excluded from the study. Initially, 27 Gy were delivered in 15 fractions in 3 weeks to the large field. Thereafter, large field received 1.8 Gy and cone down boost field received 1.4 Gy with twice a day fractinations up to 49.4 Gy. After 49.4Gy, only boost field was treated twice a day with 1.8 and 1.4 Gy. Total tumor doses were 62.2 Gy for 12 patients and 65.4 Gy for remaining 13 patients. Follow up period was ranged from 6 to 24 month. Actuarial survival rates at 6, 12, and 18 month were $88\%,\;62\%,\;and\;38\%$, respectively. Corresponding disease free suwival rates were $88\%,\;41\%,\;and\;21\%$, respectively. Actuarial cumulative local failure rates at 9, 12 and 15 month were $36\%,\;43\%,\;and\;59\%$, respectively. No significant increase of acute or late complications including radiation pneumonitis was noted with maximum follow up of 24 month. Although the longer follow up is needed, it is worthwhile to try the prospective randomized study to evaluate the efficacy of hyperfractionated radiotherapy with concomitant boost technique for unresectable non-small cell lung cancers in view of excellent tolerance of this treatment. In the future, further increase of total radiation dose might be necessary to improve local control for non-small cell lung cancer.

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Analysis of Traction Performance for Agricultural Tractor According to Soil Condition (토양 조건에 따른 농업용 트랙터의 견인 성능 분석)

  • Lee, Nam Gyu;Kim, Yong Joo;Baek, Seung Min;Moon, Seok Pyo;Park, Seong Un;Choi, Young Soo;Choi, Chang Hyun
    • Journal of Drive and Control
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    • v.17 no.4
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    • pp.133-140
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    • 2020
  • Traction performance of a tractor varies depending on soil conditions. Sinkage and slip of the driving wheel for tractor frequently occur in a reclaimed land. The objective of this study was to develop a tractor suitable for a reclaimed land. Traction performance was evaluated according to soil conditions of reclaimed land and paddy field. Field experiments were conducted at two test sites (Fields A: paddy field; and Field B: reclaimed land). The tractor load measurement system was composed of an axle rotation speed sensor, a torque meter, a six-component load cell, GPS, and a DAQ (Data Acquisition System). Soil properties including soil texture, water content, cone index, and electrical conductivity (EC) were measured. Referring to previous researches, the tractor traveling speed was set to B3 (7.05 km/h), which was frequently used in ridge plow tillage. Soil moisture contents were 33.2% and 48.6% in fields A and B, respectively. Cone index was 2.1 times higher in field A than in field B. When working in the reclaimed land, slip ratios were about 10.5% and 33.1% for fields A and B, respectively. The engine load was used almost 100% of all tractors under the two field conditions. Traction powers were 31.9 kW and 24.2 kW for fields A and B, respectively. Tractive efficiencies were 83.3% and 54.4% for fields A and B, respectively. As soil moisture increased by 16.4%, the tractive efficiency was lowered by about 28.9%. Traction performance of tractor was significantly different according to soil conditions of fields A and B. Therefore, it is necessary to improve the traction performance of tractor for smooth operations in all soil conditions including a reclaimed land by reflecting data of this study.

Reproducibility evaluation of the use of pressure conserving abdominal compressor in lung and liver volumetric modulated arc therapy (흉복부 방사선 치료 시 압력 기반 복부압박장치 적용에 따른 치료 간 재현성 평가)

  • Park, ga yeon;Kim, joo ho;Shin, hyun kyung;Kim, min soo
    • The Journal of Korean Society for Radiation Therapy
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    • v.33
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    • pp.71-78
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    • 2021
  • Purpose: To evaluate the inter-fractional position and respiratory reproducibility of lung and liver tumors using pressure conserving type(P-type) abdominal compressor in volumetric modulated arc therapy(VMAT). Materials and methods: Six lung cancer patients and three liver cancer patients who underwent VMAT using a P-type abdominal compressor were included in this study. Cone-beam computed tomography(CBCT) images were acquired before each treatment and compared with planning CT images to evaluate the inter-fractional position reproducibility. The position variation was defined as the difference of position shift values between target matching and bone matching. 4-dimensional cone-beam computed tomography(4D CBCT) images were acquired weekly before treatment and compared with planning 4DCT images to evaluate the inter-fractional respiratory reproducibility. The respiratory variation was calculated by the magnitude of excursions by breathing. Results: The mean ± standard deviation(SD) of overall position variation values, 3D vector in the three translational directions were 1.1 ± 1.4 mm and 4.5 ± 2.8 mm for the lung and liver, respectively. The mean ± SD of respiratory variation values were 0.7 ± 3.4 mm (p = 0.195) in the lung and 3.6 ± 2.6 mm (p < 0.05) in the liver. Conclusion: The use of P-type compressor in lung and liver VMAT was effective for stable control of inter-fractional position and respiratory variation by reproduction of abdominal compression. Appropriate PTV margin must be considered in treatment planning, and image guidance before each treatment are required in order to obtain more stable reproducibility

Growth Response and $CO_2$ Biomass of Chinese Cabbage and Radish under High Temperature and $CO_2$ Concentration (고온과 고농도 $CO_2$ 조건에서 배추와 무의 생육 반응 및 탄소 고정량)

  • Lee, Ji-Weon;Kim, Seung-Yu;Jang, Yoon-Ah;Moon, Ji-Hye;Lee, Woo-Moon
    • Journal of Bio-Environment Control
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    • v.15 no.4
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    • pp.364-368
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    • 2006
  • This experiment was carried out to figure out the $CO_2$ biomass and the growth response of Chinese cabbage and radish grown under the condition of high temperature and high $CO_2$ concentration to provide the information for the coming climatic change. Chinese cabbage and radish were cultivated in spring and autumn seasons under 4 treatments, 'ambient temp.+ambient $CO_2$ conc.', 'ambient temp.+elevated $CO_2$ conc.', 'elevated temp.+ ambient $CO_2$ conc.', and 'elevated temp. +elevated $CO_2$ conc.'. The 'elevated temp,' plot was maintained at 5 higher than 'ambient temp. (outside temperature)'and the 'elevated $CO_2$ cone.' plot was done in 650 ppm $CO_2$. The growth of spring-sown Chinese cabbage was worse than autumn-sown one, and was affected more by high temperature than high $CO_2$. concentration. The $CO_2$ biomass of Chinese cabbage was lower as 25.1-39.1 g/plant in spring-sown one than 54.8-63.4 g/plant of autumn-sown one. Daily $CO_2$2 fixation ability was not significantly different between spring- and autumn-sown Chinese cabbage as 1.9-2.9, 2.7-3.1 kg/10a/day, respectively. The $CO_2$ biomass of radish were 87.4-104.6 /plant in spring-sown one and 51.3$\sim$76.4 g/plant in autumn-sown one. Daily $CO_2$ fixation ability of radish were 6.2-10.1 kg/10a/day in spring-sown one and 4.6-6.9 kg/10a/day in autumn-sown one.

Selction of Useful Chemicals Reducing Soybean -Sprout Rot (콩나물 부패경감에 유용한 약제 선발)

  • 박의호;최연식
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.4
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    • pp.487-493
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    • 1995
  • This study was carried out to select useful chemicals to control pathogens inciting soybean-sprout rot. Pathogen strains were isolated from decaying soybean seedlings. The isolated strains were identified as Pseudomonas spp. (Pse. strains) through microbiological test, however, no rot-inciting fungus was isolated. Eight food additives were tested with different concentrations in controlling pathogens and harmfulness. Five chemicals(over 5% cone.) including sodium hypochlorite apparently inhibited the growth of Pse. strains on media plate, however, sodium hypochlorite was discarded due to its severe germination inhibition. Propionic acid and acetic acid inhibited the growth of Pse. strains more effectively than calcium propionate and sodium propionate relatively. As no harmful effect on seed germination and no growth retard of soybean sprouts were observed by those chemicals with lower concentration(0.5∼1.0%), these chemicals were considered to be applicable to sprout rot control judged by the effectiveness and permissible concentration as food additives.

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The hidden X suture: a technical note on a novel suture technique for alveolar ridge preservation

  • Park, Jung-Chul;Koo, Ki-Tae;Lim, Hyun-Chang
    • Journal of Periodontal and Implant Science
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    • v.46 no.6
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    • pp.415-425
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    • 2016
  • Purpose: The present study investigated the impact of 2 different suture techniques, the conventional crossed mattress suture (X suture) and the novel hidden X suture, for alveolar ridge preservation (ARP) with an open healing approach. Methods: This study was a prospective randomized controlled clinical trial. Fourteen patients requiring extraction of the maxillary or mandibular posterior teeth were enrolled and allocated into 2 groups. After extraction, demineralized bovine bone matrix mixed with 10% collagen (DBBM-C) was grafted and the socket was covered by porcine collagen membrane in a double-layer fashion. No attempt to obtain primary closure was made. The hidden X suture and conventional X suture techniques were performed in the test and control groups, respectively. Cone-beam computed tomographic (CBCT) images were taken immediately after the graft procedure and before implant surgery 4 months later. Additionally, the change in the mucogingival junction (MGJ) position was measured and was compared after extraction, after suturing, and 4 months after the operation. Results: All sites healed without any complications. Clinical evaluations showed that the MGJ line shifted to the lingual side immediately after the application of the X suture by $1.56{\pm}0.90mm$ in the control group, while the application of the hidden X suture rather pushed the MGJ line slightly to the buccal side by $0.25{\pm}0.66mm$. It was demonstrated that the amount of keratinized tissue (KT) preserved on the buccal side was significantly greater in the hidden X suture group 4 months after the procedure (P<0.05). Radiographic analysis showed that the hidden X suture had a significant effect in preserving horizontal width and minimizing vertical reduction in comparison to X suture (P<0.05). Conclusions: Our study provided clinical and radiographic verification of the efficacy of the hidden X suture in preserving the width of KT and the dimensions of the alveolar ridge after ARP.

Effects of Needle Response on Spray Characteristics In High Pressure Injector Driven by Piezo Actuator for Common-Rail Injection System

  • Lee Jin Wook;Min Kyoung Doug
    • Journal of Mechanical Science and Technology
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    • v.19 no.5
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    • pp.1194-1205
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    • 2005
  • The common-rail injection systems, as a new diesel injection system for passenger car, have more degrees of freedom in controlling both the injection timing and injection rate with the high pressure. In this study, a piezo-driven injector was applied to a high pressure common-rail type fuel injection system for the control capability of the high pressure injector's needle and firstly examined the piezo-electric characteristics of a piezo-driven injector. Also in order to analyze the effect of injector's needle response driven by different driving method on the injection, we investigated the diesel spray characteristics in a constant volume chamber pressurized by nitrogen gas for two injectors, a solenoid-driven injector and a piezo-driven injector, both equipped with the same injection nozzle with sac type and 5-injection hole. The experimental method for spray visualization was based on back-light photography technique by utilizing a high speed framing camera. The macroscopic spray propagation was geometrically measured and characterized in term of the spray tip penetration, spray cone angle and spray tip speed. For the evaluation of the needle response of the above two injectors, we indirectly estimated the needle's behavior with an accelerometer and injection rate measurement employing Bosch's method was conducted. The experimental results show that the spray tip penetrations of piezo­driven injector were longer, on the whole, than that of the solenoid-driven injector. Besides we found that the piezo-driven injector have a higher injection flow rate by a fast needle response and it was possible to control the injection rate slope in piezo-driven injector by altering the induced current.

Determination of Proto Type for 345kV CV Cable Accessories (345kV CV 케이블 접속함의 Proto Type 선정)

  • Lee, S.K.;Kim, I.T.;Son, S.H.;Choi, S.G.;Huh, G.D.;Park, W.K.
    • Proceedings of the KIEE Conference
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    • 1998.07e
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    • pp.1629-1631
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    • 1998
  • Crosslinked polyethylene (XLPE) insulated cables are now widely used all over the world for extra-high voltage underground transmission systems. Prefabricated type (compression type) joint has developed in order to shorten the assembly time and lower the possibility of contamination at site by many companies in the world. For outdoor termination, to control the electric field distribution as uniform as possible, especially for the use of extra-high voltage system. much of products are adopting the oil-impregnated condensor cone type instead of electric field control element which uses the permitivity of it only (not capacitance). For Gas-immersed termination, dimension of outer insulation bushing was determined by IEC Publication 859. The highest voltage of underground power cable system is 345kV now, in Korea. We have much of experiences of the development of prefabricated type accessories for CV cable systems (154kV, 161kV, 230kV level). So it was possible to inspect the proto type of accessories for 345kV CV cable system and seems that the need time for the development of products is reduced.

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A Robot End-effector for Biopsy Procedure Automation with Spring-Triggered Biopsy Gun Mechanism (스프링 격발형 생검총 구조를 가진 생검 시술 자동화 로봇 말단장치)

  • Won, Jong-Seok;Moon, Youngjin;Park, Sang Hoon;Choi, Jaesoon
    • Journal of Institute of Control, Robotics and Systems
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    • v.22 no.8
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    • pp.590-596
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    • 2016
  • Biopsy is a typical needle type intervention procedure performed under radiographic image equipment such as computed tomography (CT) and cone-beam CT. This minimal invasive procedure is a simple and effective way for identifying cancerous condition of a suspicious tissue but radiation exposure for the patients and interventional radiologists is a critical problem. In order to overcome such trouble and improve accuracy in targeting of the needle, there have been various attempts using robot technology. Those devices and systems, however, are not for full procedure automation in biopsy without consideration for tissue sampling task. A robotic end-effector of a master-slave tele-operated needle type intervention robot system has been proposed to perform entire biopsy procedure by the authors. However, motorized sampling adopted in the device has different cutting speed from that of biopsy guns used in the conventional way. This paper presents the design of a novel robotic mechanism and protocol for the automation of biopsy procedure using spring-triggered biopsy gun mechanism. An experimental prototype has been successfully fabricated and shown its feasibility of the automated biopsy sequence.

Particle Shapes and Optical Property of Synthesized ZnO with Amine Additives (아민첨가제를 사용하여 합성된 ZnO의 입자형상 및 광학적 특성)

  • Hyeon, Hye-Hyeon;Hyun, Mi-Ho;Lee, Dong-Kyu
    • Journal of the Korean Applied Science and Technology
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    • v.33 no.1
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    • pp.23-29
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    • 2016
  • Zinc oxide of hexagonal wurzite, is known as n-type semiconductor. It has a wide band gap energy of 3.37 eV and large exciton binding energy of 60 meV. It can be widely applied to gas sensors, laser diodes, dye-sensitized solar cells and degradation of dye waste. The use of microwave hydrothermal synthesis brings a rapid reaction rate, high yield, and energy saving. Amine additives control the different particle shapes because of the chelate effect and formation of hydroxide ion. In this study, zinc nitrate hexahydrate was used as zinc precursor. In addition, ethanolamine, ethylenediamine, diethylenetriamine, and hexamethylenetetramine are used as shape control agent. The pH value was controlled as 11 by NaOH. The shapes of zinc oxide are star-like, rod, flower-like, and circular cone. In order to analyze physical, chemical, and optical properties of ZnO with diverse amine additives, we used XRD, SEM, EDS, FT-IR, UV-Vis spectroscopy, and PL spectroscopy.