• Title/Summary/Keyword: Control and response characteristics

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Elevated folic acid results in contrasting cancer cell line growth with implications for mandatory folic acid fortification

  • Yates, Zoe;Lucock, Mark;Veysey, Martin;Choi, Jeong-hwa
    • Journal of Nutrition and Health
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    • v.49 no.2
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    • pp.72-79
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    • 2016
  • Purpose: The initiation of mandatory folic acid fortification using pteroylmonoglutamic acid (PteGlu) has reduced the rate of congenital malformations. However, it also appears to be responsible for several adverse effects, including increased cancer incidence. This may be related to physicho-chemical characteristics of PteGlu. This study examines the potential effect of high concentrations of PteGlu on a population subjected to mandatory folic acid fortification using an in vitro model. Methods: Caco-2 (colorectal cancer) and MCF7 (breast cancer) cell lines were cultured at 6 different PteGlu concentrations (0, 0.1, 1, 50, 250, and $500{\mu}g/ml$) for 6 days. Cell growth was determined using thiazolyl blue tetrazolium bromide assay. The genotype of dihydrofolate reductase 19bp deletion/insertion (DHFR 19-del) was also scored in cell lines using a restriction fragment length polymorphism technique to examine whether genetic variations may factor in cell proliferation. Results: PteGlu exhibited differential growth promoting properties between cell lines. Caco-2 cells did not show a significant growth difference at low concentrations compared to control, however, at higher concentrations, the growth showed a contrasting trend in the early experimental period, while MCF7 showed enhanced cell growth at all concentrations. The DHFR 19-del genotype differed in the two cell lines. Conclusions: Altered response to PteGlu by Caco-2 and MCF7 may reflect a tissue specific disease aetiology or genotype specific differential enzyme activity, for example by DHFR, to critical levels of PteGlu. As folic acid fortification is a blanket intervention, and DHFR and other enzyme activities vary between individuals, PteGlu intake may have an as yet undefined effect on health. These findings may be relevant when considering mandatory folic acid fortification for disease prevention.

The Effect of Characteristics of Information Security Policy on Security Policy Compliance Intention of Employees (정보보안정책의 특성이 구성원들의 보안정책 준수 행위에 미치는 영향에 관한 연구)

  • Yim, Myung-Seong
    • Journal of Digital Convergence
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    • v.11 no.1
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    • pp.27-38
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    • 2013
  • There are two elements of security policy that can have a bearing on its effectiveness: content and form. While the content of the security policy has been investigated extensively in the most of the previous studies, there is very little literature on the form of the security policy. Since the form of the policy influences its success, it is important to understand how to articulate the form of a security policy. Thus, the aim of this study is to investigate the relationship between security form and policy compliance of employees. Research results find that dimensions of security form have effect on attitude towards security compliance, subjective norm, perceived behavioral control, and perceived response costs, and besides attitude towards security compliance and subjective norm have an effect on persistent security compliance intention. The conclusions and implications are discussed.

EV Flexibility Availability for V2G Considering ISO/IEC 15118 Charging Protocol (ISO/IEC 15118기반 V2G 환경에서 전기자동차 유연성 검토)

  • Lee, Sang-Hwan;Cho, Kyu-Sang;Lee, Sang-Young;Kim, Young-Woo;Son, Sung-Yong
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.14 no.1
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    • pp.91-97
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    • 2021
  • ISO/IEC 15118 is an international communication standard for EV(electric vehicle)'s V2G implementation. In the charging/discharging control of an EV based on a communication protocol, there is inevitably a time delay when charging/discharging occurs, and the delay may limit in supplying power flexibility. In this paper, we implemented an ISO/IEC 15118-based V2G emulator and measured the charge/discharge response characteristics. As a result, the time delay appeared as 0.12ms. Accordingly, the power flexibility markets that EV can participate in under the current standard were explored.

Electro-optical characteristic analysis of liquid crystal cell using UV-treated self assembled monolayer (UV 처리된 자기 조립 단분자막을 사용한 액정 셀의 전기광학특성 분석)

  • Chan-Woo Oh;Hong-Gyu Park
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.16 no.2
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    • pp.109-115
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    • 2023
  • In this paper, we demonstrated the orientation characteristics of liquid crystals using UV-treated FSAM as alignment layer. Moreover we confirmed the FSAM properties before and after UV treatment on indium tin oxide (ITO) glass substrates using physicochemical analysis. The hydrophobic property of the FSAM surface is change to hydrophilic through UV treatment. After UV treatment the LC molecules also were uniformly and horizontally aligned on the FSAM surfaces and the pretilt angle was obviously changed 90° degrees to 0° degrees. EO characteristic of TN cell which was fabricated with UV-treated FSAM was faster response time compare to conventional PI layer. The FSAM before and after UV treatment has a superior application potential as the LC alignment layer for LCD, potentially replacing the conventional polyimide layer.

Examining the Relationship Among Restaurant Brand Relationship Quality, Attribution, and Emotional Response After Service Failure Experience (서비스 실패 경험 후 레스토랑 브랜드 품질, 귀인 및 감정반응 관계분석)

  • Jang, Gi-Hwa;Song, Soo-Ik;Oh, Sung-Cheon
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1120-1133
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    • 2018
  • The purpose of this study is to validate the failure attribution factors affecting emotional changes after a failed service by local restaurant users, and the relapse effects of the perceived failure of a customer's brand relationship. In this study, the implications of this study can be divided into the null theory and the homogenous theory, in which the study of the relationship between individual belief that influences the null theory and the post-gender emotional response is minimal. The independence of the crash response (angerous VS compassion) has been equally validated as building a belief-gathering-emotion three-step model. First, emotional BRQ (intimate and love) has a reduction effect on controllable geeks, and behavioral BRQ (relative existence) has an extended effect on controllable geeks. From a management perspective, restaurant managers should be less aware of the repeatability of a customer's service failure and call for customer sympathy. Integratedly, restaurant managers must control the customer's perception of service failure and restore the impact of the customer's BRQ on emotional reactions. A variety of service recovery measures should be established and the cerumen should be controlled. In addition, since BRQs have different effects on anger and sympathy (extended VS), different service failure recovery plans should be presented depending on the characteristics of the customer BRQ. For example, measures such as monetary compensation or fair dealing, emotional distribution to close and loving customers, and persuasion of reciprocal benefits to interdependent customers should be developed according to circumstances. This study explored the effectiveness of the geeks after a service failure and has limitations that do not take into account the various regulatory factors in the BRQ-return-Empression process. Thus, in further studies, the effects of adjusting service failure strength should be considered and a more complete model should be built.

Empirical Study on the Performance Analysis and Function of Jindo Coastal Vessel Traffic Service (진도 연안VTS의 성과 분석 및 기능에 관한 실증적 연구)

  • Jeong, Jae-Yong;Jung, Cho-Young
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.18 no.4
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    • pp.308-315
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    • 2012
  • Hebei Spirit Oil Spill that happened in 2007 had prompted the need of revisiting the coastal safety. In response to this, Korea had made an effort to implement VTS in every coastline in the country. There are a lot of theoretical studies on VTS function nowadays, but coastal VTS are less frequently studied. In this paper, performance analysis results and accident prevention activities of Jindo Coastal VTS center were summarized and the Coastal VTS function are investigated. Jindo Coastal VTS covers relatively wide area and various places with various maritime traffic characteristics are the major navigation vessels, which means that it is important to control these vessels. Since the probability of accidents due to human error is relatively high in coastal area due to negligence tendency of crews during coastal area navigation, coastal VTS has to provide sufficient assistance to navigating vessels. Like most harbour VTS, Coastal VTS provides not only main information service, navigational assistance and traffic organization services but also various services related with advanced search-and-rescue assistance, marine national security, maritime crime prevention, oil spill response, traffic services for non-service vessel, and safety supervision for water leisure boats.

Circuit Modeling and Simulation of Active Controlled Field Emitter Array for Display Application (디스플레이 응용을 위한 능동 제어형 전계 에미터 어레이의 회로 모델링 및 시뮬레이션)

  • Lee, Yun-Gyeong;Song, Yun-Ho;Yu, Hyeong-Jun
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.38 no.2
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    • pp.114-121
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    • 2001
  • A circuit model for active-controlled field emitter array(ACFEA) as an electron source of active-controlled field emission display(ACFED) has been proposed. The ACFEA with hydrogenated amorphous silicon thin-film transistor(a-Si:H TFT) and Spindt-type molibdenum tips (Spindt-Mo FEA) has been fabricated monolithically on the same glass. A-Si:H TFT is used as a control device of field emitters, resulting in stabilizing emission current and lowering driving voltage. The basic model parameters extracted from the electrical characteristics of the fabricated a-Si:H TFT and Spindt-Mo FEA were implemented into the ACFEA model with a circuit simulator SPICE. The accuracy of the equivalent circuit model was verified by comparing the simulated results with the measured one through DC analysis of the ACFEA. The transient analysis of the ACFEA showed that the gate capacitance of FEA along with the drivability of TFT strongly affected the response time. With the fabricated ACFEA, we obtained a response time of 15$mutextrm{s}$, which was enough to make 4bit/color gray scale with the pulse width modulation (PWM).

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Preventing Subway Crimes : Focusing on Sexual Offenses in the Seoul Metropolitan Subway (지하철범죄 예방전략 : 서울 지하철의 성범죄를 중심으로)

  • Roh, Sung-Hoon;Kim, Hak-Kyong
    • The Journal of the Korea Contents Association
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    • v.12 no.3
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    • pp.190-205
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    • 2012
  • The purpose of the paper is to provide policy suggestions for effectively tackling subway crimes, based on the UK and USA's crime control strategies and systems of subway crimes. The paper attempts to analyze the characteristics of subway crimes in Seoul Subways, and discovers that many of the crimes on the subways are basically 'opportunistic' crimes. In particular, crime statistics of Seoul Subways clearly show that sexual-related crimes are on the sharp increase. In this context, it is of great essence that official vigilance functions should be strengthened in order to eliminate crime opportunities in Seoul Subways. Based on such an analysis - in particular, focusing on official surveillance and response capabilities of subway passengers - the paper finally presents policy recommendations as follows: 1) an increase in the number of police officers of the Subway Police Squad, 2) an increase in the number of CCTV cameras and their effective use, 3) the development of subway riders' defence abilities, 4) strong law enforcement against minor disorder offences based on zero-tolerance policing, and 5) the reinforcement of community partnerships.

A Calculation Method for the Nonlinear Crowbar Circuit of DFIG Wind Generation based on Frequency Domain Analysis

  • Luo, Hao;Lin, Mingyao;Cao, Yang;Guo, Wei;Hao, Li;Wang, Peng
    • Journal of Power Electronics
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    • v.16 no.5
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    • pp.1884-1893
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    • 2016
  • The ride-through control of a doubly-fed induction generator (DFIG) for the voltage sags on wind farms utilizing crowbar circuits by which the rotor side converter (RSC) is disabled has being reported in many literatures. An analysis and calculation of the transient current when the RSC is switched off are of significance for carrying out the low voltage ride through (LVRT) of a DFIG. The mathematical derivation is highlighted in this paper. The zero-state and zero-input responses of the transient current in the frequency domain through a Laplace transformation are investigated, and the transient components in the time domain are achieved. With the characteristics worked out from the linear resolving without modeling simplification, the selection of the resistance in the linear crowbar circuit and the value conversion from a linear circuit to a nonlinear one is proposed to setup the attenuation rate. In terms of grid code requirements, the theoretical analysis for the time constant of the transient components attenuation insures the controllability when the excitation of the RSC is resumed and it guarantees the reserved time for the response of the reactive power compensation. Simulations are executed in MATLAB/SIMPOWER and experiments are carried out to validate the theoretical analysis. They indicate that the calculation method is effective for selection of the resistance in a crowbar circuit for LVRT operations.

Two Version Latch Technique for Metadata Management of Documents in Digital Library (전자 도서관에서 문서의 메타데이타 관리를 위한 2 버전 래치 기법)

  • Jwa, Eun-Hee;Park, Seog
    • Journal of KIISE:Databases
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    • v.29 no.3
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    • pp.159-167
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    • 2002
  • Recently, a major issue in the research of metadata is the standardization of metadata format. The new extension capability of metadata in the standardization requires some changes - storing and managing dynamic data consistently. In this paper, we define the characteristics of new metadata and propose a concurrency control called Two Version Latch (2VL). 2VL uses a latch and maintains two versions. Maintaining two versions using latch minimizes conflicts between read operation and write operation. The removal of unnecessary lock holding minimizes refresh latency. Therefore, this algorithm presents fast response time and recent data retrieval in read operation execution. As a result of the performance evaluation, the 2VL algorithm is shown to be better than other algorithms in metadata management system.