• 제목/요약/키워드: Control Multilayered

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Multilayered phospholipid polymer hydrogels for releasing cell growth factors

  • Choi, Jiyeon;Konno, Tomohiro;Ishihara, Kazuhiko
    • Biomaterials and Biomechanics in Bioengineering
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    • 제1권1호
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    • pp.1-12
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    • 2014
  • Polymer multilayered hydrogels were prepared on a titanium alloy (Ti) substrate using a layer-by-layer (LBL) process to load a cell growth factor. Two water-soluble polymers were used to fabricate the multilayered hydrogels, a phospholipid polymer with both N, N-dimethylaminoethyl methacrylate (DMAEMA) units and 4-vinylphenylboronic acid (VPBA) units [poly(MPC-co-DMAEMA-co-VPBA) (PMDV)], and the polysaccharide alginate (ALG). PMDV interacted with ALG through a selective reaction between the VPBA units in PMDV and the hydroxyl groups in ALG and through electrostatic interactions between the DMAEMA units in PMDA and the anionic carboxyl groups in ALG. First, the Ti substrate was covered with photoreactive poly vinyl alcohol, and then the Ti alloy was alternately immersed in the respective polymer solutions to form the PMDV/ALG multilayered hydrogels. In this multilayered hydrogel, vascular endothelial growth factor (VEGF) was introduced in different layers during the LbL process under mild conditions. Release of VEGF from the multilayered hydrogels was dependent on the location; however, release continued for 2 weeks. Endothelial cells adhered to the hydrogel and proliferated, and these corresponded to the VEGF release profile from the hydrogel. We concluded that multilayered hydrogels composed of PMDV and ALG could be loaded with cell growth factors that have high activity and can control cell functions. Therefore, this system provides a cell function controllable substrate based on the controlled release of biologically active proteins.

Multilayered viscoelastic beam loaded in torsion under strain-path control: A delamination analysis

  • Victor I. Rizov
    • Advances in materials Research
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    • 제13권2호
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    • pp.87-102
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    • 2024
  • This paper is focused on the delamination analysis of a multilayered beam structure loaded in torsion under strain-path control. The beam under consideration has a rectangular cross-section. The layers of the beam are made of different viscoelastic materials which exhibit continuous inhomogeneity in longitudinal direction. Since the delamination is located inside the beam structure, the torsion moments in the two crack arms are obtained by modeling the beam as an internally static undetermined structure. The strain energy stored in the beam is analyzed in order to derive the strain energy release rate (SERR). Since the delamination is located inside the beam, the delamination has two tips. Thus, solutions of the SERR are obtained for both tips. The solutions are verified by analyzing the beam compliance. Delamination analysis with bending-torsion coupling is also performed. The solutions derived are timedependent due to two factors. First, the beam has viscoelastic behavior and, second, the angle of twist of the beam-free end induced by the external torsion moment changes with time according to a law that is fixed in advance.

Highly sensitive CO sensing properties of multilayered $TiO_2$ thin films by colloidal templating

  • ;;;;;윤석진
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2010년도 하계학술대회 논문집
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    • pp.17-17
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    • 2010
  • We investigate CO gas sensing properties of multilayered TiO2 thin film gas sensors fabricated by colloidal templating of 300 nm of polymer spheres. Compared with plain films, the multilayered films show enhanced gas sensing with higher sensitivity and faster response. Also, colloidal templating by using smaller spheres (300 nm in diameter) leads to close-packed multilayered TiO2 thin films with very large-scale. This result suggest that understanding and control of the structures on the sensing properties of multilayered TiO2 thin films by colloidal templating is important in developing the films for real applications.

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Changes in Quality Characteristics of Pork Patties Containing Multilayered Fish Oil Emulsion during Refrigerated Storage

  • Jo, Yeon-Ji;Kwon, Yun-Joong;Min, Sang-Gi;Choi, Mi-Jung
    • 한국축산식품학회지
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    • 제35권1호
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    • pp.71-79
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    • 2015
  • This study was performed to determine the effect of multilayered fish oil (FO) emulsion without or with trans-cinnamal-dehyde on pork patties. Multilayered FO (-primary, -secondary, -tertiary) emulsions were prepared using a layer-by-layer deposition technique with Tween 20, chitosan, and low methoxyl pectin, and were added to pork patties at the same concentration. Pork patties were then stored for 20 d in a refrigerator ($5^{\circ}C$) to study changes in quality. The results showed that the pH value of all samples significantly decreased but cooking loss increased during storage (p<0.05). However, water-holding capacity and moisture content showed no remarkable difference between treatments and storage periods (p>0.05). All pork patties containing multilayered FO (treated samples) showed higher values for lightness and significantly lower values for yellowness compared to control pork patties (untreated sample). Lipid oxidation was higher in treated pork patties than in control pork patties during storage. In addition, lipid oxidation and total viable bacterial count in pork patties decreased as the number of coating layers increased. However, hardness, cohesiveness, and springiness of all samples showed no significant change during storage (p>0.05) as compared to fresh pork patties. Furthermore, these did not remarkable change with addition of trans-cinnamaldehyde in all pork patties. From our results, we suggest that FO emulsion did not affect the texture characteristics of fresh pork patties, indicating that it could be used to improve the quality of pork patties by contributing high-quality fat such as unsaturated fatty acids.

Design of Multilayered Suspension Mechanism for Differential Type Mobile Robot

  • Park, Jin-Ho;Roh, Se-Gon;Park, Ki-Heung;Kim, Hong-Seok;Lee, Ho-Gil;Choi, Hyouk-Ryeol
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2003년도 ICCAS
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    • pp.859-864
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    • 2003
  • This paper presents a design for the novel suspension mechanism of a two-wheeled mobile robot having two casters which is used for indoor environment. Although the indoor environment is less rough than the outdoor one, the fixed caster mechanism has some problems such as causing the robot to be immovable because robot's driving wheels do not have contact with the ground. Therefore, we tried installing a spring-damper suspension mechanism to keep driving capability and to remove pitching phenomenon. However, this suspension mechanism also has the problem, which the robot body inclined by disturbances does not return to the initial position. To deal with above problems and to accomplish desired performances, we designed the Multilayered Suspension Mechanism, which has springs and dampers working partially according to the inclined angle and angular velocity of robot body concerned with pitching. To analyze design, the equations of motion describing their dynamics were developed. Using the equations, simulation results show the improved performance. We confirm the usefulness of the Multilayered Suspension Mechanism by construction and test of a actual prototype.

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Multilayered inhomogeneous beam under prescribed angle of twist and displacements: A delamination analysis

  • Victor I. Rizov
    • Coupled systems mechanics
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    • 제13권2호
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    • pp.153-170
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    • 2024
  • The problem considered in this theoretical paper is the delamination of a multilayered inhomogeneous beam structure that has viscoelastic behaviour under angle of twist, horizontal and vertical displacements which vary smoothly with time according to prescribed laws. The cross-section of the beam is a rectangle. The layers are made of different materials which are smoothly inhomogeneous along the length of the beam. The beam under consideration represents statically undetermined structure since it is clamped in its two ends. The problem of the strain energy release rate is solved. For this purpose, the strain energy stored in the beam structure is analyzed. In order to verify the solution obtained, the strain energy release rate is found also analyzing the time-dependent compliances of the beam under prescribed angle of twist and displacements. A parametric investigation is carried-out by applying the solution obtained. Special attention is paid to the effect of the parameters which control the variation of the angle of twist and the displacements with time on the strain energy release rate.

확장칼만필터에 의하여 학습된 다층뉴럴네트워크를 이용한 헬리오스타트 태양추적오차의 모델링 (Modeling of Heliostat Sun Tracking Error Using Multilayered Neural Network Trained by the Extended Kalman Filter)

  • 이상은;박영칠
    • 제어로봇시스템학회논문지
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    • 제16권7호
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    • pp.711-719
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    • 2010
  • Heliostat, as a concentrator reflecting the incident solar energy to the receiver located at the tower, is the most important system in the tower-type solar thermal power plant, since it determines the efficiency and performance of solar thermal plower plant. Thus, a good sun tracking ability as well as its good optical property are required. In this paper, we propose a method to compensate the heliostat sun tracking error. We first model the sun tracking error, which could be measured using BCS (Beam Characterization System), by multilayered neural network. Then the extended Kalman filter was employed to train the neural network. Finally the model is used to compensate the sun tracking errors. Simulated result shows that the method proposed in this paper improve the heliostat sun tracking performance dramatically. It also shows that the training of neural network by the extended Kalman filter provides faster convergence property, more accurate estimation and higher measurement noise rejection ability compared with the other training methods like gradient descent method.

Enhancement of Mechanical Properties in Microlaminate Composite materials Produces by Physical Vapor Deposition

  • Kwon, Sik-Chol;Rha, Jong-Joo;Beck, Woon-Seung
    • 한국진공학회지
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    • 제6권S1호
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    • pp.80-88
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    • 1997
  • The attempt to enhance the strength of materials has been an important subject for materials engineering and scientists. The strength of materials is termed as the ability to support high load without excessive deformation and without breaking catastrophically. The control of dislocation densities and barriers to the movement of dislocations have been considered to be the important methods for the strengthening materials. One of the approaches is mechanical blocking of dislocations by alternately depositing material layers. The typical structure of materials is multilayered and laminated composites. The thickness of each layer is typically in the range of nanometer. Ton avoid confusion with other terminology they may be defined as microlaminate composite materials. The manufacturing process of multilayered laminate structure will be introduced. And the current theoretical theories will be reviewed in view of strengthening of microlaminte composite materials.

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A high speed electro-hydraulic no leakage servo valve using multilayered piezoelectric devices (PZT) and an observer

  • Yokota, Shinichi;Park, Jung-Ho;Fuwa, Akihiko
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1994년도 Proceedings of the Korea Automatic Control Conference, 9th (KACC) ; Taejeon, Korea; 17-20 Oct. 1994
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    • pp.54-59
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    • 1994
  • In this study, a high-speed servo valve with no outer leakage is developed, which is used to drive flexible hydraulic actuators (FHA) for extreme environments. In the valve, multilayered PZT devices are used to drive a spool directly and quickly. A bellows is also used to prevent outer leak from the clearance between the spool and the sleeve. Employing a disturbance observer, the lack of the system damping of the valve is improved by feeding back the estimated velocity of the spool, as well as the estimated disturbance is fed back to eliminate effectively the hysteresis between input voltage and output displacement of the PZT devices.

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수변구역 조성 녹지의 모니터링을 통한 식재방안 모색 - 가평군 시공지를 대상으로 - (Exploring Planting Strategies through Monitoring of a Greenspace Established in the Riparian Zone - The Case of an Implementation Site in Gapyeong County -)

  • 조현길;박혜미
    • 한국환경과학회지
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    • 제25권12호
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    • pp.1689-1699
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    • 2016
  • The growth conditions of planted trees, invasion of nuisance herbaceous species, competition between species, and effects of erosion control were monitored over five years in a riparian greenspace in Gapyeong County that was established through multilayered and grouped ecological planting. Of 156 trees planted in the upper and middle layers, 5.8% died. This tree death was attributed to poor drainage or aeration in the rooting zone from the clay-added root ball and too deep planting as well as a small-sized root ball and scanty fine roots. Of all the trees, 21.6% grew poorly due to transplant stress in the first year after planting, but they started to grow vigorously in the third year. This good growth was largely associated with soil improvement before planting, selection of appropriate tree species based on growth ground, and control of dryness and invasive climbing plants through surface mulching and multilayered/grouped planting. Mixed planting of fast-growing species as temporary trees was desirable for accelerating planting effect and increasing planting density. Thinning of fast-growing trees was required in the fifth year after planting to avoid considerable competition with target species. To reduce the invasion of herbaceous and climbing plants that oppress normal growth of planted trees, higher density planting of trees (crown opening of about 15%), woodchip mulching to a 10-cm depth, and edge planting 2 m wide were more effective than lower density planting (crown opening of 70%), no surface mulching, and no edge planting, respectively. This reduction effect was especially great during the first three years after planting. Nuisance herbaceous plants rarely invaded higher density planting with woodchip mulching over the five years. Higher density planting or woodchip mulching also showed much greater erosion control through rainfall interception and buffering than lower density planting with no mulching did. Based on these results, desirable planting and management strategies are suggested to improve the functions of riparian greenspaces.