• Title/Summary/Keyword: Contributing factor

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Renal Impairment Associated with Weekly Cisplatin and Gemcitabine Combination Therapy for Treatment of Biliary Tract Cancer

  • Galam Leem;Hee Seung Lee;Moon Jae Chung;Jeong Youp Park;Si Young Song;Seungmin Bang
    • Journal of Digestive Cancer Research
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    • v.4 no.1
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    • pp.36-38
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    • 2016
  • Biliary tract cancer, a relatively rare disease, is usually found in an unresectable stage. Weekly cisplatin plus gemcitabine has been applied as a standard first-line therapy for advanced biliary tract cancer, but almost up to 3-5% patients experience drug induced renal impairment. Many anticancer medication guidelines recommend drug adjustment when kidneys are damaged, but weekly cisplatin is somewhat low dose so that there is a controversy on reducing the dose. And it is known that the cumulative dose of cisplatin is the most important factor contributing to renal impairment. Therefore, clinicians face troubles whether or not to maintain the chemotherapy. Here, we reported a patient whose renal function (eGFR) had been decreased as the number of chemotherapy increased, so her chemotherapy should be stopped. Since we held the chemotherapy on her, the disease progressed aggressively. Weekly cisplatin regimen is just 25 mg/m2, so it may be meaningless to reduce this dose, and it is well known that cumulative dose of cisplatin is the most important factor contributing to renal impairment, it is better not to use cisplatin anymore. Therefore, we recommend that if the patient responds well to weekly cisplatin plus gemcitabine regimen, it would be beneficial to use gemcitabine alone.

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Validation of an Instrument to Measure Exercise of Self-Care Agency and its Predictors (자가간호역량의 행사 측정도구의 타당성 및 예측요인 조사)

  • 소향숙;이은숙
    • Journal of Korean Academy of Nursing
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    • v.19 no.3
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    • pp.273-284
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    • 1989
  • The aim of this investigation was to delineate concepts contributing to the Exercise of Self-Care Agency (E.S.C.A.) Scale developed by Kearney & Fleischer (1979) and to test its construct validity and its predictors. The results are summarized as follows ; 1. By means of principal factor analysis and maximal likelihood factor analysis upon data generated from 280 undergraduate students, the factors of Concern about Health Knowledge, self-Concept, Information - Seeking Behavior, Decision -making and Responsibility, Self-esteem, and Passivity emerged. The total percent of variance explained by the 6 factors was 75.1% 2. To assess factor independence and instrument homogeneity, correlations among the 6 factors were computed. The correlations ranged from .24 to .46 indicating that the factors and the items were not too similar or redundant. 3. Test-retest reliability of the total scale is r=.70. Cronbach's $\alpha$ coefficient for internal consistency of the total scale is .86 and that of the factors ranged from .750 to .661 (only factor 6 .497). 4. In additional analysis of the Exercise of Self-Care Agency Scale in relationship to Multiple Health Locus of Control, Family Environmental Scale, and Cornell Medical Index using stepwise multiple regression, the Internal Health Locus of Control Score predicted 21.8%(F=53.34, p=.0001), Family Environmental Score 8.3%(F=22.59, P=.0001), Modified Cornell Medical Index Score 5.4%(F=15.74, P=.0001) of the score of the E.S.C.A.

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Influences of Maternal Parenting Stress and Verbal Abuse on Children's Emotional Maladjustment Behaviors (어머니의 양육스트레스와 언어적 학대가 아동의 정서적 부적응 행동에 미치는 영향)

  • Lee, Sook;Choi, Jung-Mi
    • The Korean Journal of Community Living Science
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    • v.16 no.4
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    • pp.71-81
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    • 2005
  • The purpose of this research was to delineate the effect of maternal parenting stress and verbal abuse on emotional maladjustment behaviors in children. The sample consisted of 542 pairs of fifth/sixth graders and seventh/eighth graders, and their mothers. The major findings of the research were as follows: First, looking at the correlation between the mother's age/education level and the maternal parenting stress level, the maternal parenting stress level factor showed differences correlating to the mother's education level. Second, looking at the correlation between the mother's age/education level and the verbal abuse, the verbal abuse factor showed differences correlating to the mother's age/education level. Third, looking at the correlation between the maternal parenting stress level and the verbal abuse, the verbal abuse factor showed differences correlating to the maternal parenting stress level. Forth, the result of multiple regression analysis on the effects of the maternal parenting stress and verbal abuse on the children's emotional maladjustment behaviors indicated that verbal abuse was the significant contributing factor.

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A Study on the evaluation of the safety of berthing maneuver by the Analytic Hierarchy Process (계측분석법에 의한 선박 접리안 안전성의 평가방안)

  • 구자윤;이철영;우병구;전상엽
    • Journal of the Korean Institute of Navigation
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    • v.18 no.4
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    • pp.33-47
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    • 1994
  • On developing port system, the performance tests of system in relation to ship maneuver generally consists of the three parts: the channel transit, the manoeuvring in a turning basin and the docking/undocking. The quantifications of risk of an accident has priviously been difficult due to the low occurrence of accidents relative to the number of transits. Additionally, accident statistics could not be related port system because of the large number of factors contributing to the accident. such as human error, equipment failure, visibility, light, traffic. etc. In case of the channel transit, "Relative Risk Factor(RRF)" or "Relative Risk Factor for Meeting Traffic" was proposed as the as the measures derived to quantify the relative risk of accident by M.W.Smith. This factor measure the tracking performance, the turning performance and the passing performance at meeting traffic. On the other hand, the safety of berthing maneuver is not measured with a few evaluating factors as controlled due to complex controllabilites such as steering, engine, side thrusters or tugs. This work, therefore, aims to propose the evaluating measure by the Analytic Hierarchy Process(AHP). Six experimental scenarios were establised under the various environmental conditions as independent variables. In every simulation, the difficulty of maneuver was scored by captain and compared with AHP scores. The results show almost same and from which the weights of eight evaluating factors could be fixed. Additionally, the limit value of relative factor in berthing safety to six scenarios could be estimated to 0.11.e estimated to 0.11.

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Critical Factor on Selection Indoor Air Quality improving alternatives for healthcare projects (병원의 실내 공기 질 솔루션 선택에 영향을 미치는 요인들)

  • Dang Nguyen-Hong Anh;Ahn, Yong-Han
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2023.11a
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    • pp.63-64
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    • 2023
  • Indoor Air Quality is crucial in hospital projects to ensure the health and safety of patients, staff, and visitors. The research methodology comprises an comprehensive literature review, then a comprehensive questionnaire survey conducted among stakeholders involved in Vietnamese hospital projects. 15 variables were identified and categorized into four distinct groups, elucidating their influence on the adoption of advanced IAQ-enhancing technology. This study uses factor analysis, a mean score method and hypothesis test to analyze the factor result from the survey. two-step process, including an in-depth literature review and questionaire survey. The study's findings culminated in the ranking, examination, and categorization of these 15 variables, which were clustered into four essential categories: economic factors, design elements, governance strategies, and technical requirements. Additionally, the research explored viable solutions to improve indoor air quality in Vietnam's unique environmental context, examining the factors that impact the selection of such solutions. The study's outcomes yield practical recommendations for architects, engineers, and hospital administrators in enhancing IAQ within healthcare facilities. Furthermore, it presents a framework attuned to local environmental factors and building materials, contributing significantly to the existing body of knowledge on IAQ within hospital projects, particularly in the Vietnamese context.

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Analysis of Customers' Satisfaction Factors Regarding Large Food Court Service (푸드 코트 서비스의 고객만족 영향요인에 관한 연구)

  • Park, Jung-Sook
    • The Korean Journal of Community Living Science
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    • v.19 no.4
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    • pp.537-546
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    • 2008
  • The purposes of the study was to identify customers' satisfaction factors regarding foods and services in food courts in big department stores and discount stores in Seoul and Cheonan. A survey of 235 customers was conducted regarding customer satisfaction levels and factors of food and services. Customers' perceived level of attributes were identified into eight underlying dimensions by factor analysis as follows: factor 1 was "cleanliness": factor 2 "service quality": factor 3 "accuracy": factor 4 "atomosphere": factor 5 "food quality": factor 6 "menu information": factor 7 "price" and the eighth factor was "food result". Regression analysis indicated that "cleanliness" was found to be the most important factor contributing to customers' overall satisfaction. There were significant differences in customers' perceived satisfaction level of "food quality"(p<0.01), "accuracy", and "price" factors(p<0.05) between department stores and discount store. The customers' perceived satisfaction levels of "accuracy", "food quality" and "price" factor at a large store food court are higher than those of department store food court. Comparing location of food court, there were significant differences in customers' perceived satisfaction level of "accuracy" and "price" factors between in Seoul and Cheonan(p<0.001). The customers' perceived satisfaction levels of "accuracy" and "price" at the discount store in Seoul are lower than those of food court at Cheonan. It is suggested that the management should pay attention to the sanitation of their dinning halls, kitchens, hygienic dishes, hygienic water fountain, employee hygiene, and a proper place to put used dishes to increase the customers' satisfaction.

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A Study on the Parameters Contributing to the Void Crushing in the Cogging Process of Large Forged Products (대형 단조품 코깅 공정의 기공 압착 인자에 대한 연구)

  • Song, M.C.;Kwon, I.K.;Park, Y.G.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2007.05a
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    • pp.127-130
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    • 2007
  • Effect of the forging process parameters on the void crushing is the cogging process has been studied in order to find the most effective factor. The Process parameters used for this study are die width ratio, reduction ratio and pre-cooling time before cogging process. Void crushing analysis about the selected process parameters was carried out using FE analysis. The results of FE analysis were evaluated by Taguchi method. It was found that the efficiency of void crushing increases with an increase in the values of all selected process parameters and the principal factor controlling the void crushing was identified as the reduction ratio.

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Analysis of Debris Flow Characteristics Considering Forest Environmental Factors -Focusing on the Case of Mt. Daeryong in 2013- (산림환경인자를 고려한 토석류 발생특성 분석 -2013년 춘천시 대룡산 사례를 중심으로-)

  • Park, Sae-Am;Yu, Gwang-Hyeon;Yoo, Nam-Jae
    • Journal of Industrial Technology
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    • v.35
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    • pp.73-80
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    • 2015
  • This paper is research results of the case study on analyzing the characteristics of debris flow considering forest environmental factors, focusing on occurrence of landslides around Mt. Daeryoung in 2013. Extensive landslide of debris flow, caused by heavy rainfall, occurred around Mt. Daeryoung during July in 2013. Field investigation was carried out to construct the data base about forest environmental factor including topography, soil formations and forest type. Thus, contributing factors to cause the landslide of debris flow were investigated so that damages from landslides could be reduced by establishing proper measures.

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A Study on Preference Characteristics and Evaluation Factors of View by Layout Types of Apartment Houses (공동주택 배치유형별 경관 선호특성과 평가요인에 관한 연구)

  • Bong, Jong-Jin;Park, Hyang-Yong;Jeong, Hak-Gyun;Yoo, Chang-Geun;Cho, Yong-Joon
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2004.11a
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    • pp.239-244
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    • 2004
  • Large-scaled apartment housing complex at outskirts of downtown which has direct influence on urban view concentrated on improving the space outside the complex like spatial composition of individual plan design, but neglected the contribution of urban view. However, as people's orientation toward urban areas was changed to quality from quantity, concerns on urban view have been gradually increased and planning of apartment housing has been extended to complex with view contributing to urban people as a factor composing the city in resident centered spatial composition. This study is therefore to examine the characteristics of view components of 13 apartment housing complexes at Sangmu District in Gwangju Metropolitan City and their influences on evaluating view image.

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Impact of Destination Image and Satisfaction on Tourist Loyalty: Mountain Destinations in Thanh Hoa Province, Vietnam

  • LE, Hoang Ba Huyen;LE, Thi Binh
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.4
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    • pp.185-195
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    • 2020
  • The study aims to assess the impact of destination image, satisfaction and loyalty of tourists at mountain destinations in Thanh Hoa province, Vietnam. The study involves questionnaire surveys and multivariate data analysis methods (Cronbach Alpha test, EFA, CFA, SEM). Research results from 500 tourists in the mountain destinations of Thanh Hoa province demonstrate that all factors have imposed a positive impact on tourist satisfaction, specifically: The most influential factor is Natural features, followed by Human factors while the least influential factor is Infrastructure; On the other hand, research results also demonstrate that satisfaction has a substantial impact on tourist loyalty. Based on the research results, we also proposed some key solutions to enhance the destination image, thereby contributing to increased satisfaction and loyalty of tourists, including: (i) Promoting Natural Tourism Resources. (ii) Raising Awareness of Environmental Protection. (iii) Building Local Cultural Identity. (iv) Building Exclusive Tourist Products. (5) Strengthening the Support of Local Authorities for Tourism Activities. (vi) Developing a Price Policy.