• Title/Summary/Keyword: Contrast materials

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Renal Safety of Repeated Intravascular Administrations of Iodinated or Gadolinium-Based Contrast Media within a Short Interval

  • Chiheon Kwon;Koung Mi Kang;Young Hun Choi;Roh-Eul Yoo;Chul-Ho Sohn;Seung Seok Han;Soon Ho Yoon
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1547-1554
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    • 2021
  • Objective: We aimed to investigate whether repeated intravascular administration of iodinated contrast media (ICM) or gadolinium-based contrast agents (GBCAs) within a short interval was associated with an increased risk of post-contrast acute kidney injury (PC-AKI). Materials and Methods: This retrospective study included 300 patients (mean age ± standard deviation, 68.5 ± 8.1 years; 131 male and 169 female) who had undergone at least one ICM-enhanced perfusion brain CT scan, had their baseline and follow-up serum creatinine levels available, and had not undergone additional contrast-enhanced examinations 72 hours before and after a time window of interest were included. The study population was divided into three groups: single-dose group and groups of patients who had received multiple contrast administrations in the time window of interest with the minimum contrast repeat interval either within 4 hours (0-4-hour group) or between 4 to 48 hours (4-48-hour group). Multivariable logistic regression analysis was conducted to evaluate the association between AKI and repeated ICM administrations. A similar supplementary analysis was performed including both ICM and GBCA. Results: When ICM was only considered ignoring GBCA, among 300 patients, 207 patients received a single dose of ICM, 58 had repeated doses within 4 hours (0-4-hour group), and 35 patients had repeated doses between 4 to 48 hours (4-48-hour group). Most patients (> 95%) had a baseline estimated glomerular filtration rate (eGFR) of ≥ 30 mL/min/1.73 m2. AKI occurred in 7.2%, 13.8%, and 8.6% of patients in the single-dose, 0-4-hour, and 4-48-hour groups, respectively. In the 0-4-hour and 4-48-hour groups, additional exposure to ICM was not associated with AKI after adjusting for comorbidities and nephrotoxic drugs (all p values > 0.05). Conclusion: Repeated intravascular administrations of ICM within a short interval did not increase the risk of AKI in our study patients suspected of acute stroke with a baseline eGFR of ≥ 30 mL/min/1.73 m2.

The energy spectrum and phantom image quality according to mammography target-filter combinations (유방촬영장치의 타깃에 따른 에너지스펙트럼 및 팬텀영상화질)

  • Jang, Seyoung;Oh, Wanggyun;Park, Jongbae;Jin, Gyehwan
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.51-55
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    • 2013
  • When the X-ray energy is high, the X-ray penetrates the object and decrease the contrast of imaging, and when the X-ray energy is low, the X-ray increases the contrast of imaging but it is to be absorbed into the object, which in the long run increases patient's radiation exposure level. Therefore, appropriate X-ray energy is an essential element affecting the imaging quality and radiation exposure level. This study simulated the energy spectrums according to the target materials of mammography, and compared qualities of phantom imaging for the management of radiolographic quality and patient's radiation exposure level with the introduction of the mammography that employs diversified radiation quality by using new anode materials.

Study on the Fashion Design by Utilizing the China's Tibetan Dress Culture (중국 티베트 복식문화 특성을 활용한 패션디자인 연구)

  • Chen, Qiu-Qi;Suh, Seung-Hee
    • Journal of the Korean Society of Costume
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    • v.64 no.4
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    • pp.131-149
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    • 2014
  • Tibetans are one of the ethnic Chinese minorities, and this research examined the characteristics and features of their traditional costumes by investigating their historical, geographical and cultural background. This research also examined the cultural elements according to their characteristics based on Tibet's nature, religion, arts culture such as the Jang-po, Chin-sam, Kam-kjun and belts, which are used to fix the costumes. Based on such studies the traditional Tibetan costumes were set as a motif and were expressed appropriately into a contemporary style. By studying the composition of its costumes and its costume culture, the characteristics of the Tibetan costumes could be classified into four features. First, the 'variability of form' expresses a new type depending on how it is worn. Second, the 'color contrast' shows a strong visual contrast. Third, the 'difference of materials' combines different materials into one. Fourth, the 'symbolic meaning' grants meaning to the wearer. As a result of this study, by using the characteristics of the Tibetan nature culture, religion culture and art culture as a basis, two suits of clothes for each characteristics and six suits of clothes were produced as a fashion design product.

A Study on the Characteristics by Design Component Elements of the Facade in Elementary School Buildings in the 2000's (2000 년대 초등학교 교사 입면의 디자인 구성요소에 의한 특성 연구)

  • Seo, Hee-Sook
    • Korean Institute of Interior Design Journal
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    • v.19 no.5
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    • pp.38-47
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    • 2010
  • The purpose of this study is to examine the characteristics by design component elements of the facade in elementary school buildings after the 7th educational curriculum. This study choose twenty five elementary school as the subjects of the study. And among many elevations of building, an elevation that is alongside of the schoolyard is chosen because this elevation has the highest visual influence on passers-by. To begin with, this elevation is divided into the roof and the surface of a wall, The roof is divided into roof styles, existence of roof and materials. The surface of a wall is divided into design principles(balance, contrast, rhythm), the formal organization(basic elements and form, and transformation of form), the ornamental composition, materials and colors. The results of the research are summarized as follows: First of all, motifs of classical architecture were well expressed in this period and postmodern tendency had been shown until 2005. After Build Transfer Lease(BTL), however, tendency of classical architecture, contrast by the size of the form and base element by point disappeared. Instead, asymmetrical and flat tendency is expressed. Also, emphasized design of the building elevation appear by basic colors of Munsell, not motifs of classical architecture.

A Study on the Material Decomposition of Dual-Energy Iodine Image by Using the Multilayer X-ray Detector (다층구조 엑스선 검출기를 이용한 이중에너지 조영제 영상의 물질 구분에 관한 연구)

  • Kim, Jun-Woo
    • Journal of radiological science and technology
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    • v.44 no.5
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    • pp.465-471
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    • 2021
  • Dual-energy X-ray imaging (DEI) techniques can provide X-ray images that a certain material is suppressed or emphasized by combining two X-ray images obtained from two different x-ray spectrum. In this paper, a single-shot DEI, which uses stacked two detectors (i.e., multilayer detector), is proposed to reduce the patient dose and increase throughput in angiography. The polymethyl methacrylate (PMMA) and aluminum (Al) were selected as two basis materials for material decomposition, and material-specific images are reconstructed as a vector combination of these two materials. We investigate the contrast and noise performance of material-decomposed images using iodine phantoms with various concentrations and diameters. The single-shot DEI shows comparable performances to the conventional dual-shot DEI. In particular, the single-shot DEI shows edge enhancement in material-decomposed images due to the different spatial-resolution characteristics of upper and lower detectors. This study could be useful for designing the multilayer detector including scintillators and energy-separation filter for angiography purposes.

Selection of coating materials to leafy perilla seed for reducing endosulfan residue in greenhouse soil (시설재배지 토양중 잔류농약 경감을 위한 잎들깨 종자코팅제 선발)

  • Choi, Ju-Hyeon;Park, Hyeon-Ju;Park, Byung-Jun;Park, Kyung-Hun;Kim, Chan-Sub
    • The Korean Journal of Pesticide Science
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    • v.11 no.4
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    • pp.276-280
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    • 2007
  • In order to select the coating materials to perilla seed for reducing endosulfan residue greenhouse soil, this study was conducted to develop seed coating method and materials and also to evaluate the effects of seed coating on germination and color contrast between soil and perilla seed for convenient sowing work. Talc and kaoline were selected as seed coating materials because easy coating and better color contrast than shell powder or lime. Water was more effective on germination compared to alcohol, com oil and spray sticker as adhesives for seed coating.

Plasticity of Transparent Design Expressed in Contemporary Fashion (현대 복식에 표현된 투명디자인의 조형성)

  • 정연자
    • Journal of the Korea Fashion and Costume Design Association
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    • v.3 no.2
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    • pp.51-62
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    • 2001
  • This study was intended to investigate the contemporary meaning of transparent design expressed in contemporary fashion by inquiring into its plasticity expressed in contemporary design and fashion and analyzing the association between them. It used the comparative anesthetic method widely used by H. W lfflin and other scholars in eliciting the differences and similarities in styles. It attempted to investigate the plasticity of transparent design expressed in contemporary design by dividing it into the epidermal, spatial and ideological effects. Contemporary design expressed the epidermal effects such as lightness(nimbleness), smoothness, contrast and stress It expressed the spatial effects such as spatial flexibility through the interpenetration of interior and exterior spaces, expansion of the space and the like. And it expressed ideological effects such as openness, pureness, playfulness and the like. In terms of lightness, contemporary design expressed actual or visual lightness by using transparent materials. In terms of the interpenetration of interior and exterior spaces, it expressed the interpenetration of the interior space into the exterior spaces and vice versa. In terms of spatial expansion, contemporary design expressed the infinite spatial connection by drawing the exterior space into the interior space. Contrast and stress were formed by imposing visual unity on contemporary fashion by using opaque and transparent materials. In terms of openness, contemporary design expressed contemporary people's candor and dependability by making the inside of the building or object look outward. To express pureness, contemporary design used the clear and transparent image by using the glass or translucent materials taking on the pure property. To express playfulness, contemporary made use of the vagueness of the spatial boundary, the locational switching of inner and outer spaces, and interesting external forms occurring when light pass through opaque and transparent materials.

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Comprehensive Structural Characterization of Commercial Blue Light Emitting Diode by Using High-Angle Annular Dark Filed Scanning Transmission Electron Microscopy and Transmission Electron Microscopy (고각 환형 암시야 주사투과전자현미경기법과 투과전자현미경기법을 이용한 상용 청색 발광다이오드의 종합적인 구조분석)

  • Kim, Dong-Yeob;Hong, Soon-Ku;Chung, Tae-Hoon;Lee, Sang Hern;Baek, Jong Hyeob
    • Korean Journal of Materials Research
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    • v.25 no.1
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    • pp.1-8
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    • 2015
  • This study suggested comprehensive structural characterization methods for the commercial blue light emitting diodes(LEDs). By using the Z-contrast intensity profile of Cs-corrected high-angle annular dark field scanning transmission electron microscope(HAADF-STEM) images from a commercial lateral GaN-based blue light emitting diode, we obtained important structural information on the epilayer structure of the LED, which would have been difficult to obtain by conventional analysis. This method was simple but very powerful to obtain structural and chemical information on epi-structures in a nanometer-scale resolution. One of the examples was that we could determine whether the barrier in the multi-quantum well(MQW) was GaN or InGaN. Plan-view TEM observations were performed from the commercial blue LED to characterize the threading dislocations(TDs) and the related V-pit defects. Each TD observed in the region with the total LED epilayer structure including the MQW showed V-pit defects for almost of TDs independent of the TD types: edge-, screw-, mixed TDs. The total TD density from the region with the total LED epilayer structure including the MQW was about $3.6{\times}10^8cm^{-2}$ with a relative ratio of Edge- : Screw- :Mixed-TD portion as 80%: 7%: 13%. However, in the mesa-etched region without the MQW total TD density was about $2.5{\times}10^8cm^{-2}$ with a relative ratio of Edge- : Screw- :Mixed-TD portion of 86%: 5%: 9 %. The higher TD density in the total LED epilayer structure implied new generation of TDs mostly from the MQW region.

Synthesis of Ultrasound Contrast Agent: Characteristics and Size Distribution Analysis (초음파 조영제의 합성 및 합성된 초음파 조영제의 특성 분석)

  • Lee, Hak Jong;Yoon, Tae Jong;Yoon, Young Il
    • Ultrasonography
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    • v.32 no.1
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    • pp.59-65
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    • 2013
  • Purpose: The purpose of this study is to establish the methodology regarding synthesis of ultrasound contrast agent imaging, and to evaluate the characteristics of the synthesized ultrasound contrast agents, including size or degradation interval and image quality. Materials and Methods: The ultrasound contrast agent, composed of liposome and SF6, was synthesized from the mixture solution of $21{\mu}mol$ DPPC (1, 2-Dihexadecanoyl-sn-glycero-3-phosphocholine, $C_{40}H_{80}NO_8P$), $9{\mu}mol$ cholesterol, $1.9{\mu}mol$ of DCP (Dihexadecylphosphate, $[CH_3(CH_2)_{15}O]_2P(O)OH$), and chloroform. After evaporation in a warm water bath and drying during a period of 12-24 hours, the contrast agent was synthesized by the sonication process by addition of buffer and SF6 gas. The size of the contrast agent was controlled by use of either extruder or sonication methods. After synthesis of contrast agents, analysis of the size distribution of the bubbles was performed using dynamic light scattering measurement methods. The degradation curve was also evaluated by changes in the number of contrast agents via light microscopy immediate, 12 hours, 24 hours, 36 hours, 48 hours, 60 hours, 72 hours, and 84 hours after synthesis. For evaluation of the role as an US contrast agent, the echogenicity of the synthesized microbubble was compared with commercially available microbubbles (SonoVue, Bracco, Milan, Italy) using a clinical ultrasound machine and phantom. Results: The contrast agents were synthesized successfully using an evaporation-drying-sonication method. The majority of bubbles showed a mean size of 154.2 nanometers, and they showed marked degradation 24 hours after synthesis. ANOVA test revealed a significant difference among SonoVue, synthesized contrast agent, and saline (p < 0.001). Although no significant difference was observed between SonoVue and the synthesized contrast agent, difference in echogenicity was observed between synthesized contrast agent and saline (p < 0.01). Conclusion: We could synthesize ultrasound contrast agents using an evaporation-drying-sonication method. On the basis of these results, many prospective types of research, such as anticancer drug delivery, gene delivery, including siRNA or microRNA, targeted molecular imaging, and targeted therapy can be performed.

A Study on the Effective Utilization of Intensifying Screens in the Region of Diagnostic Radiology (진단방사선 영역에서 증감지의 유효이용에 관한 연구)

  • Kim, Young-Keun;Lee, Kyung-Sup
    • Journal of radiological science and technology
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    • v.22 no.1
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    • pp.43-47
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    • 1999
  • In order to obtain effective utilization of intensifying screens[$CaWO_4(W),\;Gd_2O_2S:Tb(Gd)$, BaFCl : Eu(Ba)] over the diagnostic radiology range, we calculated absorption coefficient (${\mu}$), absorption efficiency (${\eta}_{\alpha}$) and absorbed energy ratio(R) and analyzed effects of these properties on X-ray image, finally concluded as below. Regardless of presence of contrast media, absorption coefficient of Gd the highest and decreased with increase of thickness and kVp. Absorption efficiency related with absorbance of fluorescent materials showed the highest value for the Gd, and discontinuous points exhibited at around $80{\sim}90\;kVp$ and $90{\sim}100kVp$ for the Ba and the Gd, respectively. Furthermore, the absorbed energy ratio(R) correspond to contrast of reflection showed the largest value for the W in the absence of contrast media, and for the Gd in the case of the existence of it, and the ratio was decreased with increasing of incident energy. Owing to these properties, we assumed that it was more preferable to use rare earth type intensifying screen for the radiography using in the C.M.(I, Ba), while in the general radiography, $CaWO_4$ intensifying screen was applicable.

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