• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5153-5155
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• 2013

Background: Because of the gender disparity in the incidence of thyroid cancer, this study aimed to determine the association between reproductive factors and thyroid cancer. Methods: A total of 10,767 eligible women from the Khon Kaen Cohort, recruited and interviewed between 1990 and 2001, were followed up until 2011. The data were linked to the Khon Kaen Population-Based Cancer Registry to detect thyroid cancer cases. Results: There was 17 thyroid cancer cases detected, an incidence of 11.2 per 100,000 person-years, of which 70.6 % were papillary tumors. The incidence was apparently greater among those with an early age of menarche, nulligravida women, and oral contraceptive users. Conlusions: There was a trend for thyroid cancer to develop in relation to longer estrogen exposure. This evidence is inconclusive but warrants further investigation.

• Journal of Embryo Transfer
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• v.11 no.1
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• pp.71-80
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• 1996

The envelope of the rnannnalian oocyte plays crucial roles in sperm-oocyte interactions by providing sperm receptors, inducing acrosome reaction and preventing polyspermy. Understanding of properties of the zona pellucida (ZP) is essential for the artificial control of fertility in mammals. This study was carried out to produce and characterize monoclonal antibodies(MAbs) to porcine ZP proteins. Approximately 8,000 ZPs were obtained from follicular oocytes and dissolved in 40$\mu$l of double distilled water. Following immunization through foot-pad injections of Balb /c mice with a ZP solution, the popliteal lymph nodes were recovered at 2 weeks after the last injection. Hybridoma cell lines were established by fusing lymph node cells with P3X63 myeloma cells through selection using HAT medium and screening by immunofluorescence(IF) microscopy on the isolated ZP. Secreted MAbs were found to consist k chains and different heavy chains as evidenced by isotyping. Some of the MAbs demonstrated high specificity to the ZP in IF. The Mabs also showed positive cross reactivity with hamster and mouse eggs, while negative with bovine eggs. The results implicate that the MAbs can be used not only for identification of functional regions of the ZP, but also for elucidation of mechanisms involved in fertilization of mammals. The MAbs will provide basic information on biochemical anatomy of the ZP as well as can be candidates for the future contraceptive vaccines.

• The Journal of the Korea Contents Association
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• v.10 no.1
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• pp.325-333
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• 2010

Prevalence of female uterine myoma was determined using ultrasound diagnosis instrument, and correlation between health-related factors and uterine myoma was analyzed to investigate concrete factors for production of uterine myoma. Subjects in uterine myoma group and control group were asked to answer the questionnaire survey. The results were determined that prevalence of uterine mayma was 29.7%, and 40~49 aged group showed the highest level of uterine myoma by 41.4%. (p<0.05). The analysis showed that there were significant correlations between uterine myoma and collected variables such as age, marital status, occupational activity level, satisfaction level of life, weight, obesity, delivery history, breast feeding, abortion, and contraceptive experience (p<0.05).

• Proceedings of the Safety Management and Science Conference
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• 2005.05a
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• pp.177-182
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• 2005

This paper examines to focus on General Strategy of e-logistics activity for SCM(Supply Chain Management) Build-up, especially the field service logistics integration. And this research analyzes the case study(Business of Strategy Group Unit) Survey involving effective logistics management that leads customer satisfaction, seeking to find out the key elements of competitive policy. Because problems arise from the differences between their goals and structures, which cause each side to feel vulnerable to opportunism or shirking of responsibilities by the other. The goal of a logistics system is to ensure that every family planning client always receives the contraceptives partner wants, and that they are in good condition and have not expired. In order to select, procure, and distribute the right quantities of the right contraceptives, managers of the logistics system must keep informed of the rates of use of each contraceptive and of the quantity of available supplies. As a result, We propose that a firm's e-logistics safe strategy is an important locus innovation and a crucial source of value creation for the firm its suppliers, partners, and customers.

• Journal of Korea Association of Health Promotion
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• v.2 no.2
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• pp.137-148
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• 2004

Objective : To identify the risk factors for postmenopausal osteoporosis in Korea Materials and methods : Bone mineral density (BMD) at the lumbar spine and femoral neck was measured by dual energy X-ray absorptiometry in 808 apparently normal postmenopausal Korean women. Questions about life style, demographic parameters, medical history and social habits etc. were asked on these women; 2ll women with normal bone mineral density, and 597 women with osteopenia or osteoporosis. Results 'Age of >50 years, low body mass index (BMI; <18.5 kg/m2), long duration of menopause(>10 years), and previous history of fracture were associated with increased prevalence of osteopenia or osteoporosis. Women without the outside activity also showed a higher frequency of low bone mass, Risk for osteopenia or osteoporosis was low in women with high BMI (>23 kg/m2) and women with job. The prevalence of low bone mass appeared to be independent of the following parameters: socioeconomic status, familial history, smoking, drinking, exercise, previous use of oral contraceptive, coffee or milk consumption, and degree of sunlight exposure. Conclusion 'Age, BMI, duration of menopause, previous history of fracture and degree of outside activity are the risk factors for postmenopausal osteoporosis in Korea.

• Journal of Haehwa Medicine
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• v.19 no.1
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• pp.1-7
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• 2010

Melasma is a common disorder that causes dark colored patches. It generally causes brown spots on the face, especially on the forehead, cheeks, and upper lips. The pattern of patches has bilateral symmetry in yellowish-brown to gray-brown colors. It is much more common in women than in men. Melasma is considered to be caused by environmental and physical constitutional factors and often occurs when a woman's hormone changes by pregnancy or the use of oral contraceptive pills. It is important to combine oriental medicine and Sasang constitutional medicine for treatment of Melasma. Normal treatment of Melasma includes warming oneself, removal of the emotional stress factors, and good nutrition.

• Korean Journal of Health Education and Promotion
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• v.31 no.5
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• pp.59-70
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• 2014

Objectives: The purpose of this study was to identify the current status of contraception use and analyze factors affecting contraception use among Korean adolescents. Methods: This cross sectional study used secondary data from the 2013 Adolescent Health Behavior Online Survey (KYRBS), which included a nationally representative sample of middle and high school students. A total of 3,475 adolescents who had experienced sexual intercourse were included in the study. Results: Almost 4.8% of total adolescents experienced sexual intercourse. Only 26.8% of them had sex with contraception. The significant predictors related to contraception use were as follows: sexual intercourse experience after drinking (OR=2.02) and living with mother (OR=3.00) for male middle school student, first intercourse experience (OR=2.04) for female middle school students, and first intercourse experience (OR=1.59) and intercourse experience after drinking (OR=0.56) for male high school students. On the other hand, there were no predictors for female high school students. Conclusions: Development and application of effective strategies according to gender and school level are needed to increase contraception rate of adolescents.

• Korea journal of population studies
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• v.9 no.2
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• pp.42-52
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• 1986

An attempt had been made to obtain current information on induced abortion among currently married women aged 15 to 44. The source of data was 1985 National Fertility and Family Planning Survey conducted by Korea Institute for Population and Health in may 1985. 1. At the time of the survey, 53 percent of currently married women aged 15 to 44 had experienced induced abortion: 25.5 percent of the respondents who had experienced induced abortion only one time and another 27.6 percent more than two times. 2. The proportion of women who had experienced induced abortion seemed to increase according to the advance in age. It seemed that there was no significant difference in the experience rate of induced abortion by academic career, and there was inverse relationship between the experience rate of induced abortion and the age at first marriage. The experience rate if induced abortion by the number of living children was highest among those who had three children as 65.6 percent. 3. To analyze the effect of induced abortion on fertility, this study employed multiple regression analysis as a statistical technique. Instead of index representing fertility level the number of living children served as dependent variable. Independent variables used in analysis included age, age at first marriage, education level, ideal number of children, religion, frequency of induced abortion, total number of pregnancies and participation in labor force. Standardized partial regression coefficient of induced abortion was no less than -0.61. So, it can be concluded that induced abortion offered the great contribution on the birth control. A consistant health education and efficient management of family planning program would be essential for effectiveness of contraceptive practice.

• Women's Health Nursing
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• v.25 no.1
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• pp.46-59
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• 2019

Purpose: To determine associations of traumatic events and post-traumatic stress disorder (PTSD) with sexual autonomy and identify factors influencing sexual autonomy among female university students of North Korean defectors. Methods: A cross-sectional, descriptive study was performed with a total of 103 female students who completed a structured online self-report survey from January 7 to March 31, 2018. This study was conducted using questionnaires on interpersonal trauma scale, the Traumatic Scale for North Korean Refugees (TSNKR), and sexual autonomy measurement for college students. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation coefficients, and multiple linear regression with SPSS WIN 23.0 program. Results: Traumatic events, PTSD, and sexual autonomy scores were $3.96{\pm}3.07$, $31.47{\pm}10.75$, and $52.66{\pm}6.89$, respectively. PTSD was positively correlated with traumatic events (r=.22, p=.030). Sexual autonomy was inversely correlated with PTSD (r=-.25, p=.010). Contraceptive use, PTSD, and voluntary sexual debut explained 26% of sexual autonomy of participants. Conclusion: To improve sexual autonomy of young women from North Korea, reproductive intervention programs including contraception, sexual assertiveness training, and psychoeducation to reduce PTSD need to be developed and implemented.

• Journal of Animal Science and Technology
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• v.63 no.1
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• pp.58-68
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• 2021

Several herbs including Artemisia are known to possess conceptive property. In the present study, mouse spermatozoa were incubated with ethanol extract of Artemisia vulgaris leaves. The effect of extract on acrosome exocytosis was studied by labeling spermatozoa with fluorescein isothiocyanate (FITC) peanut agglutinin and by staining with Coomassie blue. Viability and membrane integrity were studied by Trypan-blue staining and hypo-osmotic swelling test. Artemisia extract at very low concentration caused precocious acrosome reaction and loss of sperm viability. Acrosome reaction increased remarkably from 22.63% to 88.42% with increasing extract concentration from 0 to 2,000 ㎍/mL. However, the viability loss of spermatozoa was increased from 11.71% in control to 63.73% in samples treated, evaluated by Trypan-blue staining method. Membrane damage caused by the extract, evaluated by hypo-osmotic swelling test was even low, ranging from 2.27% to only 24.23%. These results indicate that Artemisia extract might block fertilization by causing precocious acrosome exocytosis in spermatozoa. A direct contraceptive effect was tested by injecting the plant extract into the vagina of female mice and then allowing them to mate with normal males. The treated female mice delivered significantly fewer litters in comparison to the control.