• Title/Summary/Keyword: Continuous-Time Model

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Assay development and HTS on microfluidic Lab-on-a-chip

  • Yang, Eun-Gyeong
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2002.07a
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    • pp.73-78
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    • 2002
  • Microfluidic lab-on-a-chip (LOC) systems have enabled a new generation ofassay technologies in chemical and biomedical sciences. Caliper's microfluidic LOC systems contain a network of microscopic channels through which fluids and chemical are moved in order to perform experiments. The main advantages of these continuous-flow devices are integration and automation of multiple steps in complex analytical procedures to improve the reproducibility of the results, and eliminated the manual labor, time and pipetting errors involved in analyses. The present talk is devoted to give a brief introduction of microfluidic basics and to present in applying continuous-flow microchips to drug screening with model enzyme assays.

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Continuous Variable Regression Analysis for Frequency of Damage Analysis in Heat Pipe (연속형 변수 회귀분석을 통한 열수송관 파손빈도 분석)

  • Myeongsik Kong;Jaemo Kang;Sungyeol Lee
    • Journal of the Korean GEO-environmental Society
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    • v.24 no.12
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    • pp.47-52
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    • 2023
  • In order to efficiently maintain heat pipes operated by district heating operators, the facility history and damage history data built by the operator are used to identify key independent variables that are related to the occurrence of damage. Afterwards, the correlation with the frequency of damage was analyzed, and a basic model for estimating the frequency of damage was derived. Considering the correlation with the estimation model based on the use time currently being used by domestic and foreign district heating operators, a simple regression analysis basic model was presented as the independent variable with the highest correlation between continuous variables such as the use time, pipe diameter, burial depth, and insulation level of monitoring system, and the frequency of damage. The remaining independent variables were reflected as factors that modify and supplement the basic model. As a result of the analysis, as in previous research cases, it was confirmed that the analysis model between use time and frequency of damage had the highest correlation between the two variables and could be used as a basic model. Pipe diameter, burial depth, and insulation level of monitoring system information have also been confirmed to have a correlation with the frequency of damage, so they can be used as factors to supplement the basic model.

Time series regression model for forecasting the number of elementary school teachers (초등학교 교원 수 예측을 위한 시계열 회귀모형)

  • Ryu, Soo Rack;Kim, Jong Tae
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.2
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    • pp.321-332
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    • 2013
  • Because of the continuous low birthrates, the number of the elementary students will decrease by 17% in 2020 compared to 2011. The purpose of this study is to forecast the number of elementary school teachers until 2020. We used the data in education statistical year books from 1970 to 2010. We used the time-series regression model, time series grouped regression model and exponential smoothing model to predict the number of teachers for the next ten years. Consequently time-series grouped regression model is a better model for forecasting the number of elementary school teachers than other models.

Intention to Use of Personal Cloud Services: Focusing on the Security Factors (보안요인을 중심으로 한 개인용 클라우드 서비스 사용의도)

  • Lee, Jae Seok;Kim, Kyoung-jae
    • Knowledge Management Research
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    • v.18 no.4
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    • pp.237-260
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    • 2017
  • Recently, with the proliferation of smart phones and mobile devices and the increase in the speed of mobile Internet, IT services are increasingly used in smart phones and mobile devices in a different way from the past. That is, a cloud service that downloads and uses data stored in the server in real time is expanding, and as a result, the security due to the continuous Internet connection of the user becomes a problem. In this study, we analyzed the relationship between factors affecting the continuous use of personal cloud service by using technology acceptance model. In addition to the technology acceptance model, confidentiality, privacy, accessibility, innovation, and self-efficacy were extracted from the existing research with emphasis on the characteristics of the cloud service and security factors. Moreover, the difference of intention to use among genders was verified through structural equation modeling with survey data from 262 personal cloud service users.

Development of Linear DC Motor Pilot Model for High Thrust (고추력용 리니어직류모터 Pilot 모델 개발)

  • 정재한;서경일;박재완;박재한
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2000.11a
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    • pp.1002-1005
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    • 2000
  • The goal of this study is to develop a linear DC motor with high thrust, speed and stiffness for machine tool. In the first phase of this study, We has made a pilot model and measuring system. Using the measuring system, We could finished the performance test of the pilot model, which continuous thrust is 1, 391N. Experimental values agree with the theoretical results well. In a certain sense, We are expecting the realization of linear motor with continuous thrust of 6, 000 to 7, 000N next time.

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Stochastic (Q, r) Inventory Model for Two-echelon Distrubution System (2단계 분배체계를 위한 확률적(Q,r)재고모형)

  • 심재홍;최규탁;김정자
    • Journal of the Korean Operations Research and Management Science Society
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    • v.23 no.1
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    • pp.43-65
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    • 1998
  • This paper develops a two-echelon inventory model with time-weighted partial backorders. The presented model assumed to follow continuous review (Q. r) policy for both the retailers and the central warehouse under stochastic demand. A heuristic method to find an optimum-tending solution for total variable system cost per year incurred at the central warehouse and retailers in a system is suggested. To show the usefulness of the above model, numericla examples are illustrated for verification and validation purpose.

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Feedforward actuator controller development using the backward-difference method for real-time hybrid simulation

  • Phillips, Brian M.;Takada, Shuta;Spencer, B.F. Jr.;Fujino, Yozo
    • Smart Structures and Systems
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    • v.14 no.6
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    • pp.1081-1103
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    • 2014
  • Real-time hybrid simulation (RTHS) has emerged as an important tool for testing large and complex structures with a focus on rate-dependent specimen behavior. Due to the real-time constraints, accurate dynamic control of servo-hydraulic actuators is required. These actuators are necessary to realize the desired displacements of the specimen, however they introduce unwanted dynamics into the RTHS loop. Model-based actuator control strategies are based on linearized models of the servo-hydraulic system, where the controller is taken as the model inverse to effectively cancel out the servo-hydraulic dynamics (i.e., model-based feedforward control). An accurate model of a servo-hydraulic system generally contains more poles than zeros, leading to an improper inverse (i.e., more zeros than poles). Rather than introduce additional poles to create a proper inverse controller, the higher order derivatives necessary for implementing the improper inverse can be calculated from available information. The backward-difference method is proposed as an alternative to discretize an improper continuous time model for use as a feedforward controller in RTHS. This method is flexible in that derivatives of any order can be explicitly calculated such that controllers can be developed for models of any order. Using model-based feedforward control with the backward-difference method, accurate actuator control and stable RTHS are demonstrated using a nine-story steel building model implemented with an MR damper.

Large Vocabulary Continuous Speech Recognition Based on Language Model Network (언어 모델 네트워크에 기반한 대어휘 연속 음성 인식)

  • 안동훈;정민화
    • The Journal of the Acoustical Society of Korea
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    • v.21 no.6
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    • pp.543-551
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    • 2002
  • In this paper, we present an efficient decoding method that performs in real time for 20k word continuous speech recognition task. Basic search method is a one-pass Viterbi decoder on the search space constructed from the novel language model network. With the consistent search space representation derived from various language models by the LM network, we incorporate basic pruning strategies, from which tokens alive constitute a dynamic search space. To facilitate post-processing, it produces a word graph and a N-best list subsequently. The decoder is tested on the database of 20k words and evaluated with respect to accuracy and RTF.

Region-based Q-learning for intelligent robot systems (지능형 로보트 시스템을 위한 영역기반 Q-learning)

  • Kim, Jae-Hyeon;Seo, Il-Hong
    • Journal of Institute of Control, Robotics and Systems
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    • v.3 no.4
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    • pp.350-356
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    • 1997
  • It is desirable for autonomous robot systems to possess the ability to behave in a smooth and continuous fashion when interacting with an unknown environment. Although Q-learning requires a lot of memory and time to optimize a series of actions in a continuous state space, it may not be easy to apply the method to such a real environment. In this paper, for continuous state space applications, to solve problem and a triangular type Q-value model\ulcorner This sounds very ackward. What is it you want to solve about the Q-value model. Our learning method can estimate a current Q-value by its relationship with the neighboring states and has the ability to learn its actions similar to that of Q-learning. Thus, our method can enable robots to move smoothly in a real environment. To show the validity of our method, navigation comparison with Q-learning are given and visual tracking simulation results involving an 2-DOF SCARA robot are also presented.

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Biosorption of Cr (VI) ions by Ficus religiosa barks: Batch and continuous study

  • Karthick, S;Palani, R;Sivakumar, D;Meyyappan, N
    • Membrane and Water Treatment
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    • v.13 no.5
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    • pp.209-217
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    • 2022
  • In the present research, Ficus religiosa Bark (FRB) is used as an adsorbent for the removal of heavy metal Cr (VI) ions. This Ficus religiosa Bark was characterized by Scanning Electron Microscope, Fourier transform infrared Spectroscopy, Thermo Gravimetric Analyzer and the results showed that activated adsorbent have high adsorption capacity and withstand even in high temperature. Batch and Continuous experiments were conducted to determine the effect of various parameters such as pH, contact time, adsorbent dose and initial metal concentration. The biosorption followed pseudo first order kinetic model. The adsorption isotherms of Cr (VI) on Ficus religiosa fitted well with the Temkin model. In Batch study, maximum biosorption capacity of Cr (VI) was found to be 37.97 mg g-1 (at optimal pH of 2, adsorbent dosage of 0.3 grams and concentration of Cr (VI) is100 mg L-1). The Continuous mode of study shows that 97% of Cr (VI) ion removal at a flow rate of 15 ml min-1. From the results, selected Ficus religiosa Bark has the higher adsorption capacity for the removal of Cr (VI) ions from wastewater.