• 사상체질의학회지
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• 제16권1호
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• pp.130-147
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• 2004

To investigate the antioxidant capacity of traditional Korean herb medicines, water extracts from 42 species which has been used for the Taeum constitution of Sasang Medicine, were tested on their antioxidant activity using radical scavenging effects against ABTS. Some Of them showed strong antioxidant capacities at $50{\mu}g$ concentration. And, antioxidant capacities of 2 prescriptions extract of Sasang Medicine, Cheongsimyeonja-tang and Yeoldahanso-tang, in the different concentration ($10{\mu}g$, $50{\mu}g$, and $100{\mu}g$) were determined. At the same time, the antiperoxidation effects of these 2 prescriptions extract were determined. Lipid peroxidation in brain homogenates induced by NADPH and $ADF-Fe^{2+}$ was strongly inhibited by Cheongsimyeonja-tang in vitro. The above-mentioned 2 prescriptions are a potent antioxidant capacity and antiperoxidation activity, further investigation into the in vivo antioxidant therapeutic potential for treatment of human disorders in brain tissue.

• 사상체질의학회지
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• 제19권2호
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• pp.170-178
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• 2007

1. Objective This study was aimed to screen the potential antitumor activity of one kinds of Korean medicinal herb extracts against cancer cell lines and to evaluate the growth inhibition effect of L-1210 and S-180 cancer cell lines. 2. Methods It confirmed Anemarrhena asphodeloides extracts to screen the potential antitumor activity. Then, it was extracted with 4 kinds of solvents ; hexane, ethyl acetate, butanol and $H_2O$, and the Growth inhibition effect of these extracts were determined against cancer cell and normal cell. The results were as follows : The IC50(50% inhibitory concentration) values of Anemarrhena asphodeloides extracts were shown to be $253{\mu}g/ml$ against L-1210 cell lines. The IC50 values of ethyl acetate extracts were shown to be $915{\mu}g/ml$ against L-1210 cell lines. The IC50 values of butanol extracts were shown to be $52.3{\mu}g/ml$, $485{\mu}g/ml$ against L-1210, S-180 cell lines, respectively. The butanol extracts were more selectively effective than other extracts to cancer cell lines. 3. Conclusion From these data, it could be concluded that the Anemarrhena asphodeloides extracts to the Growth inhibition effect of L-1210 and S-180 cancer cell lines.

• 사상체질의학회지
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• 제13권3호
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• pp.114-117
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• 2001

1. Object: The primary purpose of this case study is to report that a Tae-Yin-In patients with sweaty scrotum and dysuria was treated with 'Chung sim youn ja tang' and then his symptom decreased 2. Subject: A male obese patient with sweaty scrotum and dysuria that visit Kirin oriental hospital to be treated for obesity 3. Method: The patient was to have a very low calory diet and to exercise for an hour daily and to take a Herb-medicine, 'Chung sim youn ja tang'. Change of his subjective symptom, sweaty scrotum and dysuria, was measured by VAS(Visual Analog Scale) 4. Result: A Tae-Yin-In patients with sweaty scrotum and dysuria was treated with 'Chung sim youn ja tang' and Change of his subjective symptom, sweaty scrotum and dysuria, was measured by VAS(Visual Analog Scale) then his symptom decreased. 5. Conclusion: 'Chung sim youn ja tang' may have an effect on Treatment of sweaty scrotum and dysuria. Further study is needed how to conclud 'disease pattern of constitution' accroding with co-symptom.

• 사상체질의학회지
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• 제23권3호
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• pp.304-317
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• 2011

1. Objectives: Aromatherapy is one of the alternative medical treatments by flavors of essential oils extracted from plants. This study was to investigate the classification of aroma essential oils by Sasang Constitution for clinical applications. 2. Methods: 1) We searched scientific name of aroma essential oils and scientific name of herbs, classify aroma essential oils according to Sasang Constitution. 2) If the method 1) is impossible, sort them by regard of aroma essential oils' flavors, specific characters and efficacies. 3. Results: Aroma essential oils suitable for Soeumin are 27 kinds, for Soyangin and Taeeumin are each 16 kinds, and for Taeyangin are 5 kinds.(Duplicates are allowed.) The cases which can not be classified clearly, are 10 kinds, so they are able to consider the Constitution of the more than two-phase. 4. Conclusions: Most of aromatic herbs are warm and spicy by pre-reports. So, aroma essential oils suitable for Soeumin are most often. After this study, studies about Sasang Constitutional herb recipes and more clinical studies are needed.

• 사상체질의학회지
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• 제36권1호
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• pp.31-42
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• 2024

Introduction This case series report an attempt to treat Sasang constitutional medicine on Soyangin patients with unspecified hot flush. Methods The patients in this case were diagnosed as Soyangin cold pattern and treated with herb medicine Dojeokgangi-tang. Treatment outcome was monitored retrospectively. Results Persistent hot flush significantly improved to normal levels in all 3 Soyangin patients, and 2 out of 3 showed the effect within 4 weeks, those with more chronic symptoms required more time. Discussion This study suggests the significance of Sasang constitutional medicine treatment in Soyangin patients with Hot flush. Additionally, the characteristics of patients with hot flush presented in this study were verified as meaningful diagnostics indicator of Soyangin lesser yang wind damage. Furthermore, it emphasizes the value of original symptoms as a standard for evaluating treatment effectiveness.

• KSBB Journal
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• 제32권1호
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• pp.46-53
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• 2017

There are four types (So-Eum, So-Yang, Tae-Eum, Tae-Yang type) in Sasang constitutional medicine (SCM). In SCM, not only people but also herbal medicine are classified into four types. To date, there has been very little evidence of experimental classifications in SCM. So, we adapted Issatchenkia orientalis in two different culture media made from the herbal medicines for So-Eum and for So-Yang type. And the adapted Issatchenkia orientalis was inoculated into another eight culture media made from the herbal medicines for So-Eum and for So-Yang type. The mass reduction was measured every 12 hours for 2 days. Then, we analyzed the statistical differences of herbal medicines for So-Eum and for So-Yang type. There were significant differences of variables (R: rate of change in mass reduction, S: convex degree of mass reduction graph) in herbal medicine media for So-Eum (p=0.001, 0.001, respectively.). Suggesting a microbiological method of Sasang medicine research, current study may contribute to the establishment of experimental Sasang constitutional herbal medicine.

• 사상체질의학회지
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• 제2권1호
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• pp.199-211
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• 1990

In order to investigate the hemostatic effect of Gamiikwiseungyangtang, prothrombin time was measured after administered with the extract of Ikwiseungyangtang added four several herb drugs and Ikwiseungyangtang extract added four several herb drugs extract to mice orally. The results were as follows: 1. Gamiikwiseungyangtang was recognized significance on the plasma prothrombin time in normal mice. 2. Gamiikwiseungyangtang was recognized significance on the plasma prothrombin time in hypoprothrombinemic mice. 3. Prothrombin time of Gamiikwiseungyangtang on normal and hypoprothrombinemic mice was not recognized effective difference according to two types. From above results, Gamiikwiseungyangtang indicates that it is effect on the hemostatic activity.

• 사상체질의학회지
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• 제23권2호
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• pp.164-173
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• 2011

1. Objectives: The purpose of this study is to understand the origin, the progressive changes and the constructive principles of Packhaoleejung-tang (白何烏理中湯) 2. Methods: Packhaoleejung-tang and other related prescriptions were analyzed in terms of their pathological indications, based on "Donguisusebowon Chobongwon (東醫壽世保元 草本卷)", "Donguisusebowon Gabobon (東醫壽世保元 甲午本)", "Donguisusebowon Sinchukbon (東醫壽世保元 辛丑本)", "Dongmuyugo (東武遺稿)", "Shanghanlun (傷寒論)". 3. Results and Conclusions: (1) The origin of Packhaoleejung-tang is leejung-tang from "Shanghanlun (傷寒論)". Packhaoleejung-tang inherited some of the principles from "Shanghanlun (傷寒論)" Insamkeiji-tang (2) "Gabobon(甲午本)"'s one prescription Hyangsaleejung-tang emphasizes the effect of lossen up by using Pogostemonis Herb (藿香),Amomi Fructus(砂仁). "Gabobon(甲午本)"'s another prescription Packhaoleejungtang emphasizes the effect of warm up stomach by using Cinnamomum cassia Blume (桂枝), Allium sativum Linne (獨頭蒜), Cynanchum wilfordii(白何首烏). "Sinchukbon(辛丑本)"'s prescription Packhaobujaleejungtang emphasizes the effect of warm up stomach by using Aconitum carmichaeli(附子) (3) The Packhaoleejung-tang is composed of 7 herbs. Atractlodis Rhizoma White(白朮), Glycyrrhizae Radix(甘草), Paeoniae Radix Alba(白芍藥) support Soeumin's spleen root (脾元), and Zingiberis Rhizoma(乾薑),Cinnamomum cassia Blume (桂枝, Cynanchum wilfordii(白何首烏) warm up stomach. Citri Pericarpium(陳皮) circulate Qi and encourage the descension of Yin.

• 사상체질의학회지
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• 제21권1호
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• pp.44-52
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• 2009

1. Objectives Jeong-Jo's death has many mistery. So we understand rightly Jeong-Jo's death. we inspect closely medical records of 20 days before death(in The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書)， GukSoBoGam(國朝寶鑑). We understand medical treatment before death. It is based on Jeong-Jo's Constitution. So we trace the cause of a Jeong-Jo's death rightly. 2. Methods According to The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書) GukSoBoGam(國朝寶鑑). We found out Jeoung-Jo's Sasang constitutional elemet. We point on Jeoung-Jo's nature and emotion, temperament and talent, features and way of speaking, physical appearance, healthy state, ordinary symptom, pathological syndromes and pharmacology. so documentary records was worthy of notice. 3. Results and conclusions 1. Jeong-Jo has prominent cheekbones,flat face. It belong to Tae-eum. 2. Jeong-Jo's physical appearance is mild,around,large. It belong ro Tae-eum. 3. Jeong-Jo's favorite food and herb were belong to Tae-eum interior febrile disease herb. which is Exhale Dispersing Qi 4. So even though Jeoung-Jo is Tae-eum, He had a weak body. It main cause that Smoking, insomnia, heave work, Hwa disease. 5. Jeong-Jo's is Interior febrile disease induced form the liver affected by heat in Tae-eumin

• 사상체질의학회지
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• 제22권4호
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• pp.40-48
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• 2010

1. Objectives Herbal Extracts are used in Korean Oriental Medicine clinics. The sixty eight kinds of single herbal extracts and fifty six kinds of mixed herbal extracts has been using since the first year of execution of Korean medicine national insurance policy in 1987. This paper was performed to make a guideline of using herbal extracts. Single herbal extracts and mixed herbal extracts were discussed and classified according to Sasang constition. 2. Methods The sixty eight single herbal extracts were classified into four categories according to Sasang Constitution and fifty six mixed herbal extracts were classified by six Korean oriental medical doctors. Mixed herbal extracts were considered in terms of drug roles[sovereign, minister, assistant and courier(君臣佐使)] or most included ingredient herb. 3. Results Sasang constitutions which were suitable for fifty six mixed herbal extracts were Soeumin(46.4%), mixed constitution(39.2%) and Soyangin(8.9%), Taeeumin(5.3%). Sasang constitutions which were suitable for sixty eight single herbal extracts were Soeumin(47.1%), Soyangin(32.4%) and Taeeumin(20.6%). 4. Conclusions The rate of Soeumin herbal extracts was the most highest among all constitutions. It is regarded that warming and enforcing herb medicine were most used in all prescriptions.