• Korean Journal of Pharmacognosy
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• v.52 no.2
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• pp.112-117
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• 2021

Helianthus annuus L. has been reported with various pharmacological activities such as antibacterial, antidiabetic, and antioxidant effects. According to recent studies, H. annuus L. is known to contain components such as phenolic compounds, flavonoids, alkaloids, sesquiterpenoids, and lignans. The seeds of H. annuus L. have been reported to contain chlorogenic acid and di-O-caffeoylquinic acid as major components. However, studies on the main components and content of leaves of H. annuus L. are still incomplete. Therefore, in this study, the contents of four major components of H. annuus L. were evaluated by simultaneous quantitative analysis with high performance liquid chromatography (HPLC)-diode array detector (DAD). The isolated four compounds Caffeoylquinic acid(CQA), 3,4-dicaffeoylquinic acid(3,4-DCQA), 3,5-dicaffeoylquinic acid(3,5-DCQA) and 4,5-dicaffeoylquinic acid(4,5-DCQA) were shown in a large linearity with a correlation coefficient (R²) of 0.99. In addition, as a result of intra-inter day analysis of four major compounds by the analysis method of this study, the accuracy of 88.46% or more and less than 112.85% and excellent precision of less than 3% were shown, the content analysis showed CQA (0.383±0.018 mg/g), 3,4-DCQA (0.282±0.017 mg/g), 3,5-DCQA (1.109±0.068 mg/g), and 4,5-DCQA (0.673±0.020 mg/g).

• Journal of Korean Tunnelling and Underground Space Association
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• v.12 no.4
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• pp.329-340
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• 2010

Mechanical behavior of underground cavity construction such as tunnel is very difficult to estimate due to complexity and uncertainty of ground. Prediction of behavior according to excavation of tunnel mainly uses method utilized of model test or numerical analysis. But scale model test is difficult to reappear field condition, numerical analysis is also very hard to seek choice of suitable constituent model and input data. To solve this problem, this paper forecasted the deformation of tunnel that applied to information of crown settlement and convergence, RMR in weathered granite by using the regression analysis. The result of the analysis shows that the crown settlement according to excavation occurs approximately 70~80% of total displacements within about 20 days. As a result of the prediction of crown settlement and convergence, an exponential function becomes more accurate at measurements than an algebraic function. Also this paper got a correlation in comparison of RMR and displacements of 6 sections.

• Herbal Formula Science
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• v.28 no.4
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• pp.313-325
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• 2020

Objectives : To explore the associated potential pathways and molecular targets of Hwangryunhaedok-tang(HHT) by the approaches of network pharmacology and bioinformatics in traditional chinese medicine(TCM). Methods : Hwangryunhaedok-tang constituent drugs(Coptidis Rhizoma, CR; Scutellariae Radix, SR; Phellodendri Cortex, PC; Gardeniae Fructus, GF) and their processing types were searched from TCM systems pharmacology(TCMSP). The databases of TCMSP, Kyoto Encyclopedia of Genes and Genomes(KEGG), MCODE and STRING were used to gather information. The network of bioactive ingredients and target gene was constructed by Cytoscape software(version 3.8). Results : A total of 94 HHT active compounds(CR, 12; SR, 35; PC, 33; GF, 14, respectively) were found, and HHT were identified by TCMSP. Applications of KEGG and MCODE analysis indicates that total of 6 bioactive ingredients in the top 10% ranking were obtained and 32 diseases of HHT were screened. The molecular pathway analysis revealed that HHT exerts cancer, inflammation and cerebrovascular diseases effects by acting on several signaling pathway. In addition, HHT found that three genes(e.g. SPIN1, TRIM25, and APP) correlate with the aforementioned diseases. Conclusions : This study showed that network pharmacology analysis is useful to elucidate the complex mechanisms of action of HHT.

• Structural Engineering and Mechanics
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• v.18 no.5
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• pp.645-669
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• 2004

In seismic analysis of moment-resisting frames, beam-column connections are often modeled with rigid joint zones. However, it has been demonstrated that, in ductile reinforced concrete (RC) moment-resisting frames designed based on current codes (to say nothing of older non-ductile frames), the joint zones are in fact not rigid, but rather undergo significant shear deformations that contribute greatly to global drift. Therefore, the "rigid joint" assumption may result in misinterpretation of the global performance characteristics of frames and could consequently lead to miscalculation of strength and ductility demands on constituent frame members. The primary objective of this paper is to propose a rational method for estimating the hysteretic joint shear behavior of RC connections and for incorporating this behavior into frame analysis. The authors tested four RC edge beam-column-slab connection subassemblies subjected to earthquake-type lateral loading; hysteretic joint shear behavior is investigated based on these tests and other laboratory tests reported in the literature. An analytical scheme employing the modified compression field theory (MCFT) is developed to approximate joint shear stress vs. joint shear strain response. A connection model capable of explicitly considering hysteretic joint shear behavior is then formulated for nonlinear structural analysis. In the model, a joint is represented by rigid elements located along the joint edges and nonlinear rotational springs embedded in one of the four hinges linking adjacent rigid elements. The connection model is able to well represent the experimental hysteretic joint shear behavior and overall load-displacement response of connection subassemblies.

• Journal of Korean Society on Water Environment
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• v.21 no.6
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• pp.651-658
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• 2005

The Non-parametric Analysis is powerful in data test especially for the non- normality water quality data. The data at three monitoring stations of the Tam-Jin River were evaluated for their normality using Skewness, Q-Q plot and Shapiro-Willks tests. Various constituent of water quality data including temperature, pH, DO, SS, BOD, COD, TN and TP in the period of January 1994 to December 2004 were used as dataset. Shapiro-Willks normality test was carried out for a test 5% significance level. Most water quality data except DO at monitoring stations 1 and 2 showed that data does not normally distributed. It is indicating that non-parametric method must be used for a water quality data. Therefore, a homogeneity was conducted by Mann-Whitney U test (p<0.05). Two stations were paired in three pairs of such stations. Differences between stations 1, 2 and stations 1, 3 for pH, BOD, COD, TN and TP were meaningful, but Tam-Jin 2 and 3 stations did not meaningful. In addition, a narrow gap of the water quality ranges is not a difference. Categories in which all three pairs of stations (1 and 2, 2 and 3, 1 and 3) in the Tam-Jin River showed difference in water quality were analyzed on TN and TP. The results of in this research suggest a right analysis in the homogeneity test of water quality data and a reasonable management of pollutant sources.

• Journal of Gastric Cancer
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• v.17 no.4
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• pp.342-353
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• 2017

Purpose: This study evaluated the changes in nutritional status based on quality of life (QoL) item-level analysis to determine whether individual QoL responses might facilitate personal clinical impact. Materials and Methods: This study retrospectively evaluated QoL data obtained by the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30) and Quality of Life Questionnaire-Stomach (QLQ-STO22) as well as metabolic-nutritional data obtained by bioelectrical impedance analysis and blood tests. Patients were assessed preoperatively and at the 5-year follow-up. QoL was analyzed at the level of the constituent items. The patients were categorized into vulnerable and non-vulnerable QoL groups for each scale based on their responses to the QoL items and changes in the metabolic-nutritional indices were compared. Results: Multiple shortcomings in the metabolic-nutritional indices were observed in the vulnerable groups for nausea/vomiting (waist-hip ratio, degree of obesity), dyspnea (hemoglobin, iron), constipation (body fat mass, percent body fat), dysphagia (body fat mass, percent body fat), reflux (body weight, hemoglobin), dry mouth (percent body fat, waist-hip ratio), and taste (body weight, total body water, soft lean mass, body fat mass). The shortcomings in a single index were observed in the vulnerable groups for emotional functioning and pain (EORTC QLQ-C30) and for eating restrictions (EORTC QLQ-STO22). Conclusions: Long-term postoperative QoL deterioration in emotional functioning, nausea/vomiting, pain, dyspnea, constipation, dysphagia, reflux, eating restrictions, dry mouth, and taste were associated with nutritional shortcomings. QoL item-level analysis, instead of scale-level analysis, may help to facilitate personalized treatment for individual QoL respondents.

• Culinary science and hospitality research
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• v.20 no.3
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• pp.186-200
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• 2014

This study investigates the effect of foodservice employees' mentoring part on expressing emotions and self-esteem by conducting a survey. The data collected from the survey were analysed by SPSS18.0 and AMOS for frequency analysis, exploratory analysis, confirmatory factor analysis, correlation analysis and structure equation modeling. The results are as follows. First, the mentoring part was a significant constituent for achieving an organization's objective because a mentor and a mentee could interact and sympathize through personal recommendation, consultation and support for reducing psychological stress. Second, the mentoring part had a positive effect on organizational ability to adapt. Third, organizational conflicts influenced self-esteem. As the results indicated, the foodservice industry should manage an effective mentoring system for high quality services and the attainment of an organizational goal.

• Proceedings of the KIEE Conference
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• 1998.07c
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• pp.1220-1223
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• 1998

High Power Laboratory is the facility for building to simulate the various phenomena generated from electric systems of the real world and to test making and breaking capability, switching capability and durability of circuit breaker, switchgear and other electric utilities, moreover, load equipments which contain capacitor bank is installed for studying the diverse effects originated from the constituent of load through entire systems or receiving end. Such factors, abnormal voltage or current, can be serious in electrical systems, especially, in the case caused by capacitive components such as overvoltage or inrushcurrent, the problems may be more fatal to the systems. In this paper, the optimal design of capacitor bank which will be equipped in High Power Laboratory, which is for simulating as closely as the practical phenomena resulted from the capacitive currents, and the verification aided by computer simulations are presented. For this, analysis of the circuit characteristics according to the standards which can be criteria of the capacitive current tests and the test circuit configuration in accordance with the analysis are proposed in prelude. In the body of the paper the optimal design of capacitor bank has been obtained on the basis of all conditions mentioned above and the test circuit configuration with LGIS test requirements. furthermore, analysis and verification for the design are derived by EMTP. finally, evaluation for the capacitor bank design and further study plan are concluded.

• Communications of Mathematical Education
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• v.36 no.2
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• pp.201-227
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• 2022

The purpose of this study was to develop an instrument measuring mathematics anxiety suitable for Korean High school students. In order to achieve this study purpose, the study was conducted according to the procedure of setting components of mathematics anxiety, developing questions, and verifying validity and reliability. First, in order to set the components of mathematic anxiety, previous studies on mathematic anxiety. Through this, six factors of mathematic anxiety were derived. Next, new questions were developed for each of the six constituent factors. The 122 questions were revised and supplemented through two content validity tests, and the final instrument for mathematics anxiety consisted of 49 questions of 6 factors. Finally, to verify the validity and reliability of the measurement instrument for mathematics anxiety, a survey was conducted on 1,848 students from 16 universities in Seoul and the metropolitan area. Next, a validity analysis was conducted with the 1,645 responses, excluding students who answered that there was no mathematics anxiety. As a result of exploratory factor analysis, 15 out of 49 questions were removed. Six factors were named individual characteristics, pressure on achievement, abstraction in mathematics, teaching and learning style, parental attitudes, and cumulative mathematics subjects. As a result of confirmatory factor analysis, the model fit was found to be appropriate, and the convergence validity and discriminant validity were found to be good.

• Journal of The Korea Institute of Healthcare Architecture
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• v.29 no.3
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• pp.7-15
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• 2023

Purpose: This study was conducted with the aim of presenting spatial planning directions for evacuation spaces based on an analysis of the performance of horizontal evacuation during the early stages of fire incidents in a geriatric hospital. Methods: Based on a review of previous studies, the research model was designed by establishing occupancy conditions, evacuation, and fire scenarios. The analysis model was developed by considering vulnerable areas in terms of evacuation movement and analyzing the results of evacuation performance. Furthermore, the study analyzed the improvement in evacuation performance by arranging refuge areas. Results: The results of the study are as follows. Firstly, vulnerability spots were identified in terms of evacuation performance by schematizing Required Safe Egress Time, Available Safe Egress Time, and their differences. Secondly, the Required Safe Egress Time in the adjacent public spaces along the escape routes of occupants was found to be higher compared to the Available Safe Egress Time. Thirdly, the results of the correlation analysis between the difference in Available Safe Egress Time and Required Safe Egress Time during the early stages of a fire, as well as their constituent factors, demonstrated that user congestion is a more significant factor in compromising evacuation safety than the physical changes in the fire condition. Fourthly, the analysis of evacuation time was conducted by designating refuge areas where occupants can evacuate within a sufficient timeframe. This led to a decrease in the Required Safe Egress Time. Implications: This study is expected to be used as data on the direction of evacuation space planning to improve the evacuation performance of Geriatric Hospital.