• 통합자연과학논문집
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• 제8권2호
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• pp.89-98
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• 2015

Chemoattractant receptor homologous molecule expressed on Th2 cells (CRTh2) is a G-protein coupled receptor targeted for inflammatory diseases such as asthma, allergic rhinitis and atopic dermatitis. In this study, pharmacophore modeling and comparative molecular field analysis (CoMFA) were performed on the series of 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl) acetic acids derivatives. Five highly active compounds were used for generation of pharmacophore models using GASP module. The best pharmacophore model was selected and used as template for the alignment of compounds which was used for CoMFA analysis. The best predictions obtained for CoMFA was $q^2=0.545$, $r^2=0.756$. The predictive ability of the model was investigated using 15 test set compounds. Contour maps suggested that presence of bulky substituents at $5^{th}$ position of benzene ring connected to suphur atoms attached to imidazol ring will increase the activity of the compounds. The results obtained from this study will be useful to design more potent CRTh2 antagonists.

• 대한기계학회논문집A
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• 제32권1호
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• pp.77-82
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• 2008

Strain-gauges have been dominantly used to measure strain at various points on a rotor, however, either a slip ring or telemetry has to be used to send sensor signals to data acquisition instruments at stationary side. Both slip ring and telemetry have numerous inherent problems which force severe limitations in real applications. This paper introduces a new rotor condition monitoring system using FBG(Fiber Bragg Grating) sensors and a rotary optical coupler. A single optical fiber with many FBG sensors is installed on the rotor and an optical dynamic interrogator is installed at stationary side. The sensor signal connection between rotating part and stationary part is made by the rotary optical coupling method which makes use of light's unique characteristic-light travels through space. Broad band light source from the interrogator travels to the optical fiber on the rotor and reflected FBG sensor signals travel back to the optical fiber on stationary side and are connected to the interrogator. Rotary optical coupler's insertion loss change due to rotation is compensated by using a reference sensor installed at the center of the rotor. The proposed system's performance has been successfully demonstrated by accurately measuring strains at 5 points on a blade rotating at high speed.

• 대한수학회보
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• 제57권1호
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• pp.207-218
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• 2020

Some modular representations of reflection groups related to Weyl groups are considered. The rational cohomology of the classifying space of a compact connected Lie group G with a maximal torus T is expressed as the ring of invariants, H*(BG; ℚ) ≅ H*(BT; ℚ)^W(G), which is a polynomial ring. If such Lie groups are locally isomorphic, the rational representations of their Weyl groups are equivalent. However, the integral representations need not be equivalent. Under the mod p reductions, we consider the structure of the rings, particularly for the Weyl group of symplectic groups Sp(n) and for the alternating groups A_n as the subgroup of W(SU(n)). We will ask if such rings of invariants are polynomial rings, and if each of them can be realized as the mod p cohomology of a space. For n = 3, 4, the rings under a conjugate of W(Sp(n)) are shown to be polynomial, and for n = 6, 8, they are non-polynomial. The structures of H*(BT^n-1; 𝔽_p)^A_n will be also discussed for n = 3, 4.

• Archives of Pharmacal Research
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• 제22권6호
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• pp.585-591
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• 1999

The linker which plays a role in connecting a polymer with a scaffold has become an important part n solid-phase reaction. To develop a new linker for alcohols and carbohydrates, dihydropyran moiety was selected in this study. New linker, 1-($4^{l},5^{l}$-dihydro-5H-pyranyl)-7-hydroxyheptan-3-one (5) was synthesized via four steps from $\delta$-valerolactone. This can be called as DDHP-linked Wang resin due to double dihy-dropyran rings. To the one pyran ring of new linker 5 was added Wang resin and other alcohols and carbohydrates as scaffolds were then added successfully to the another pyran ring. Carbohydrate and hydroxyl resins were connected via new linker in a 70% loading yield. The detachment of glucose moiety in the presence of PPTS (2 equiv.) in 1:1 n-buteanol/1,2-dichloroethane at $60^{\circ}C$ for 12 h was carried out quantitatively. When certain combinatorial chemical works are carried out using this dihydropyran linker, Wang resin itself can be recovered. Its fact is particularly very important in industry, because recovered resins can be recycled.

• Bulletin of the Korean Chemical Society
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• 제7권5호
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• pp.331-334
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• 1986

The crystal structure of thiamin tetrahydrofurfuryl disulfide, one of the ring-opened derivatives of thiamin, has been determined by the X-ray diffraction methods. The crystal is monoclinic with cell dimensions of a = 8.704 (1), b = 11.207 (2), c = 21.260 (3) ${\AA}$ and ${\beta}$ = 92.44 (2)$^{circ}$, space group P2$_{1}$/c and Z = 4. The structure was solved by direct methods and refined to R = 0.076 for 1252 observed reflections measured on a diffractometer. The molecule assumes a folded conformation in which the pyrimidine and the tetrahydrofurfuryl rings are on the same side of the ethylenic plane. The pyrimidinyl, N-formyl and ethylenic planes are mutually perpendicular to each other and the N(3)-C(4) bond retains a single bond character. The structure is stabilized by an intramolecular N(4'${\alpha})-H{\cdots}O(2{\alpha}$) hydrogen bond. The molecules are connected via N(4'${\alpha}$)-H{\cdots}(N3')$ and O(5${\gamma})-H{\cdots}(N1')$ hydrogen bonds, forming a two-dimensional hydrogen-bonding network. The tetrahydrofurfuryl ring is dynamically disordered. The overall conformation as well as the packing mode is very similar to that of thiamin propyl disulfide.

• 정보보호학회논문지
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• 제1권1호
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• pp.38-46
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• 1991

본 논문에서는 ID 정보를 이용한 키 분배방식을 제안했다. 이 방식에서는 Diffie-Hellman 방식에서 사용하는 공개 화일의 불법 변경 등의 공격에 대한 위험이 제거되는 장점을 가지고 있는 방식이다. 또한, 본 논문에서는 2명 이상의 회의용 키를 생성하는 ID 정보를 이용한 회의용 키 분배방식을 제안하였다. 가입자들은 링 네트워크(ring network)를 구성하고 있다고 가정하였다. 각 가입자들간의 전송정보들은 각 가입자의 ID 정보를 이용하여 인증된다. 제안한 방식의 안정성은 큰 수의 소인수 분해 및 이산대수 계산 문제에 근거한다.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제10권7호
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• pp.191-198
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• 2021

분산 딥러닝은 각 노드에서 지역적으로 업데이트한 지역 파라미터를 동기화는 과정이 요구된다. 본 연구에서는 분산 딥러닝의 효과적인 파라미터 동기화 과정을 위해, 레이어 별 특성을 고려한 allreduce 통신과 연산 오버래핑(overlapping) 기법을 제안한다. 상위 레이어의 파라미터 동기화는 하위 레이어의 다음 전파과정 이전까지 통신/계산(학습) 시간을 오버랩하여 진행할 수 있다. 또한 이미지 분류를 위한 일반적인 딥러닝 모델의 상위 레이어는 convolution 레이어, 하위 레이어는 fully-connected 레이어로 구성되어 있다. Convolution 레이어는 fully-connected 레이어 대비적은 수의 파라미터를 가지고 있고 상위에 레이어가 위치하므로 네트워크 오버랩 허용시간이 짧고, 이를 고려하여 네트워크 지연시간을 단축할 수 있는 butterfly all-reduce를 사용하는 것이 효과적이다. 반면 오버랩 허용시간이 보다 긴 경우, 네트워크 대역폭을 고려한 ring all-reduce를 사용한다. 본 논문의 제안 방법의 효과를 검증하기 위해 제안 방법을 PyTorch 플랫폼에 적용하여 이를 기반으로 실험 환경을 구성하여 배치크기에 대한 성능 평가를 진행하였다. 실험을 통해 제안 기법의 학습시간은 기존 PyTorch 방식 대비 최고 33% 단축된 모습을 확인하였다.

• 인터넷정보학회논문지
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• 제8권5호
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• pp.21-33
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• 2007

오버레이 네트워크는 물리적 네트워크를 기반으로 하는 가상의 컴퓨터 네트워크로서, 오버레이 네트워크의 노드들은 가상의 링크 또는 논리적 링크로 상호 연결된 것으로 각 링크는 물리적 링크상의 경로와 일치한다. 이러한 오버레이 네트워크는 분산 환경에서 이질적인 자원의 공유에 적합하다. 그러나 오버레이 네트워크는 신뢰적인 통신에 제한이 많으므로 오버레이 네트워크에서의 실패 탐지는 네트워크의 신뢰성을 향상시키는데 중요한 요소이다. 본 논문에서는 분산 환경에서 전형적인 실패 탐지가 가져야 하는 조건들을 살펴보고 HRing 오버레이 네트워크(Hierarchical Ring Overlay Network)에서 수행할 수 있는 실패 탐지와 회복 기법을 제안한다. 제안된 방법은 크게 실패 탐지 단계와 실패 회복 단계로 구분되며, HRing 오버레이가 갖는 특징들을 활용하여 실패 탐지를 수행하기 때문에 불필요한 네트워크 트래픽을 감소시킬 수 있으며 네트워크의 확장성과 유연성을 보장할 수 있다. 본 논문에서는 또한 제안된 실패 탐지 및 회복 기법에 대한 분석과 시뮬레이션을 통한 실험적 평가를 통해 성능을 평가하였다.

• 한국정보통신학회논문지
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• 제21권5호
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• pp.906-912
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• 2017

본 논문에서는 실내 디지털 TV(DTV) 수신용 3소자 광대역 준-야기 안테나 (quasi-Yagi antenna; QYA) 설계 방법에 대해 연구하였다. 제안된 QYA는 마이크로스트립(microstrip; MS) 선로와 다이폴 투사기를 급전하는 코플래너스트립(coplanar strip; CPS) 선로 간 밸런을 새로운 형태로 구성하였다. 제안된 밸런은 MS 선로 종단을 CPS에 단락핀으로 연결하여 구성하였으며, CPS 선로와 반사기를 원형 링 도체로 연결하였다. 제안된 구조의 안테나를 지상파 DTV 방송 주파수 대역인 470-806 MHz 대역에서 동작하도록 설계하였다. FR4 기판 상에 $270mm{\times}150mm$ 크기로 제작된 안테나는 전압정재파비가 2 이하인 주파수 대역 470-820 MHz, DTV 대역 내 배열 축 방향으로의 이득 > 4.0 dBi, 전후방비 > 8.4 dB 인 양호한 특성을 보인다.

• Journal of Communications and Networks
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• 제14권6호
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• pp.653-661
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• 2012

High-availability seamless redundancy (HSR) is a redundancy protocol for Ethernet networks that provides two frame copies for each frame sent. Each copy will pass through separate physical paths, pursuing zero fault recovery time. This means that even in the case of a node or a link failure, there is no stoppage of network operations whatsoever. HSR is a potential candidate for the communications of a smart grid, but its main drawback is the unnecessary traffic created due to the duplicated copies of each sent frame, which are generated and circulated inside the network. This downside will degrade network performance and might cause network congestion or even stoppage. In this paper, we present two approaches to solve the above-mentioned problem. The first approach is called quick removing (QR), and is suited to ring or connected ring topologies. The idea is to remove the duplicated frame copies from the network when all the nodes have received one copy of the sent frame and begin to receive the second copy. Therefore, the forwarding of those frame copies until they reach the source node, as occurs in standard HSR, is not needed in QR. Our example shows a traffic reduction of 37.5%compared to the standard HSR protocol. The second approach is called the virtual ring (VRing), which divides any closed-loop HSR network into several VRings. Each VRing will circulate the traffic of a corresponding group of nodes within it. Therefore, the traffic in that group will not affect any of the other network links or nodes, which results in an enhancement of traffic performance. For our sample network, the VRing approach shows a network traffic reduction in the range of 67.7 to 48.4%in a healthy network case and 89.7 to 44.8%in a faulty network case, compared to standard HSR.