• The Journal of Traditional Korean Medicine
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• v.15 no.1
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• pp.128-144
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• 2006

This Study aims at looking into the use of oriental medical services in treating hypertension. The first objective to be explored through this study is the morbidity caused by the disease, classifying them by age, gender, and occupation. The second is to determine the regular use of anti-hypertensive medicine and their efficacy in controlling blood-pressure. The third is to investigate the use-rate and satisfaction of oriental medical service. 838 households across the country, were asked to answer questionnaires for the period of time from Apr. to Jun. 2005. The conclusion from the survey can be summarized as following. The age of which the first medical diagnosis of hypertension were made showed lower in males, those with higher education and income. The study showed females were more active in blood-pressure control, with their frequent monitoring of blood-pressure for the past year. With age, people in under 50 age group proved to be less active. The management of high blood pressure was more effective in group with regular dosage compared to group with irregular use of anti-hypertensive medication, but their difference was minimal. Also, group with no medication showed signs of blood-pressure control. The use of oriental medical service for the past year, were more frequent in groups with lower education, either low or high income, old age, females and occupations in agriculture, forestry and fishing industry. Results were similar in both general population and high blood-pressure patient group. Females, people over 51 years old and with lower education showed more intentions in utilizing oriental medical services in the future. Results were similar in both general population and high blood-pressure patient group. It is necessary to offer a more accurate information on oriental medical treatments. Also, a systematic reform to reduce the patient's share of the treatment cost, as well as, heightening public awareness on the infirmity of present blood-pressure management system is crucial.

• Journal of the korean academy of Pediatric Dentistry
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• v.48 no.1
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• pp.122-128
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• 2021

Short root anomaly (SRA) is a rare dental condition with abnormally short and blunt root morphology. It mostly affects maxillary central incisors symmetrically and only has been observed in permanent teeth. A 9-year-old girl was referred from a local dental clinic for short root development in mixed dentition with no symptoms. Radiographic and intraoral examinations revealed SRA on upper and lower incisors and mandibular first molars along with other dental anomalies such as enamel hypoplasia and dens invaginatus. During long - term follow - up for 5 years, her mixed dentition has changed to permanent dentition and generalized SRA was observed in all permanent teeth. Cephalometric radiograph also revealed the calcification between the anterior and posterior clinoid processes described as a sella turcica bridge which was reported associating with dental anomalies. Early diagnosis of SRA is emphasized for successful management and prevention of root resorption and tooth loss. This report aimed to present a rare case of generalized SRA along with other dental anomalies and sella turcica bridging in a female patient through long - term follow - up.

• Journal of Korean Tunnelling and Underground Space Association
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• v.23 no.4
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• pp.253-263
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• 2021

Concrete structures are damaged by aging and external environmental factors. This type of damage is to appear in the form of cracks, to proceed in the form of spalling. Such concrete damage can act as the main cause of reducing the original design bearing capacity of the structure, and negatively affect the stability of the structure. If such damage continues, it may lead to a safety accident in the future, thus proper repair and reinforcement are required. To this end, an accurate and objective condition inspection of the structure must be performed, and for this inspection, a sensor technology capable of detecting damage area is required. For this reason, we propose a deep learning-based image processing algorithm that can detect spalling. To develop this, 298 spalling images were obtained, of which 253 images were used for training, and the remaining 45 images were used for testing. In addition, an improved loss function and data augmentation technique were applied to improve the detection performance. As a result, the detection performance of concrete spalling showed a mean intersection over union of 80.19%. In conclusion, we developed an algorithm to detect concrete spalling through a deep learning-based image processing technique, with an improved loss function and data augmentation technique. This technology is expected to be utilized for accurate inspection and diagnosis of structures in the future.

• Applied Chemistry for Engineering
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• v.30 no.4
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• pp.429-434
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• 2019

A lateral flow immunoassay platform utilizing antibody functionalized water soluble CdSe/ZnS semiconductor quantum dots (QDs) was developed for the analysis of human serum amyloid A-1 (hSAA1) in a buffer solution. hSAA1 was chosen as a target protein because it is regarded as a potential biomarker associated with early diagnosis and prognosis in patients of lung cancer. The immunoassay strip on a nitrocellulose membrane was fabricated by spraying two lines composed of a test line with a monoclonal antibody against hSAA1 (10G1) (anti hSAA1) and a control line of anti-chicken IgY. While the CdSe/ZnS QDs synthesized in an organic phase were transferred to a water phase by ligand exchange using carboxylic acid modified alkane thiol. The QDs was then conjugated to monoclonal antibody against hSAA1 (14F8) [anti hSAA1 (14F8)] and used as a fluorescent detection probe. The sequential lateral flow of hSAA1 in different concentration and QDs-anti hSAA1 (14F8) complex allowed to form the surface sandwich complex of anti hSAA1 (10G1)/hSAA1/QD-anti hSAA1 (14F8), which was then analyzed using fluorescence microscope. A 100 nM concentration of hSAA1 protein can be detected by naked eyes under an optimized lateral flow buffer condition with a sensing time of 5 mins.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.1
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• pp.32-41
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• 2019

Objective : The purpose of this study is to develop a personal health record(PHR) application of atopic dermatitis in Korean Medicine(KM). Methods : We have identified the items necessary to provide an PHR application that helps to record and manage the symptoms of an atopic dermatitis in KM. We also derived the symptom collection process and method and applied it to the application. Results : In this study, the types of symptoms collected for atopic dermatitis were derived. Symptoms include daily check, stool/urine/sleep, daily emotion, meal management, symptom photographs, SCORAD, quality of life, progress check, original symptom, pediatric health check, weakness check, and subjective symptoms. The recording cycle can be divided into the first, daily, weekly, specific day, and subjective. We developed the PHR application of atopic dermatitis in KM by deriving the type of symptoms and symptom recording process. The app organized menus into dashboards, checklists, daily checks, and health records. Conclusions : We developed a PHR application for atopic dermatitis by deriving symptom collection items of atopic dermatitis and developing symptom collection process and collection technique. The app does not make an accurate diagnosis of atopic dermatitis symptoms, but it helps facilitate symptom collection and helps to identify or predict a person's health condition. It can also be used for medical treatment through sharing symptoms with Korean medicine. Patients are able to communicate in both directions on a daily, weekly, self-aware basis, at the request of a doctor, to record their symptoms and use them for medical purposes. If the doctor asks for a progress check to refer to the next examination, it can be written through the system. This manages atopic dermatitis in daily life and can be used in the clinical field.

• Journal of the Korean GEO-environmental Society
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• v.19 no.12
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• pp.41-46
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• 2018

The wireless sensor network system has the advantage of confirming the behavior of the entire facility by improving the disadvantages of conventional monitoring system. As a result, it is widely proposed as safety diagnosis and measurement of structures, water management systems, and management systems for dam structures. However, there is a lack of research that can evaluate the condition of facilities such as safety at the same time as monitoring. In this study, it is proposed a wireless sensor network system which can evaluate the behavior characteristics of facilities and evaluate the safety status for improving the technical disadvantages on conventional monitoring system. The geotechnical risk factors for the reservoir dam facility were evaluated and the limit values for the risk factors causing the failure of the facility were set. In other words, the system was set up so that the risk factors can be measured and the limit status can be evaluated immediately for each factor. In this study, numerical analysis is carried out for seepage and slope stability analysis using the typical cross section for reservoir dams. The stress-porewater coupling finite difference numerical analysis is performed for establishing the limit displacement for reservoir dam structures. It is developed a system that can estimate the time to reach the critical value by regression analysis using the measured datas.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.3
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• pp.291-296
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• 2021

This study examined the effects of the forward head posture on the maximum mouth opening of the jaw joint and the muscle activity and asymmetry of the temporalis and masseter. The craniovertebral angle was measured in 50 subjects (23.10±2.73 years) who met the selection requirements of the study. The maximum mouth opening, muscle activity, and muscle asymmetry were measured by reducing 0%, 10%, and 20%. As the craniovertebral angle decreased, the maximum mouth opening decreased (p<.001), the muscle activity of the right and left temporalis decreased (p<.001), and the muscle activity of the left temporalis also decreased. (p<.01). The asymmetry rate of the added muscles of the left and right temporalis, left and right temporalis, and masseter increased according to the change in condition (p<.01). The results of this study are expected to help establish a treatment strategy and comprehensive diagnosis for the temporomandibular joint and present a theoretical basis of manual therapy and therapeutic exercises used for the treatment of TMD.

• Journal of Life Science
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• v.30 no.12
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• pp.1118-1127
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• 2020

Alzheimer's disease causes progressive neuronal loss that leads to cognitive disturbances. It is not currently curable, and there is no way to stop its progression. However, since medical treatment for Alzheimer's disease is most effective in the early stages, early detection can provide the best chance for symptom management. Biomarkers for the diagnosis of Alzheimer's disease include amyloid β (Aβ) deposition, pathologic tau, and neurodegeneration. Aβ deposition and phosphorylated tau can be detected by cerebrospinal fluid (CSF) analysis or positron emission tomography (PET). However, CSF sampling is quite invasive, and PET analysis needs specialized and expensive equipment. During the last decades, blood-based biomarker analysis has been studied to develop fast and minimally invasive biomarker analysis method. And one of the remarkable findings is the involvement of platelets as a primary source of Aβ in plasma. Aβ can be transported across the blood - brain barrier, creating an equilibrium of Aβ levels between the brain and blood under normal condition. Interestingly, a number of clinical studies have unequivocally demonstrated that plasma Aβ42/Aβ40 ratios are reduced in mild cognitive impairment and Alzheimer's disease. Together, these recent findings may lead to the development of a fast and minimally invasive early diagnostic approach to Alzheimer's disease. In this review, we summarize recent advances in the biomarkers of Alzheimer's disease, especially the involvement of platelets as a source of peripheral Aβ production and its potential as a blood-based biomarker.

• The Journal of the Korea Contents Association
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• v.22 no.3
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• pp.71-80
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• 2022

In the past, fish diseases were bacterial in aqua farms, but in recent years, the frequency of fish diseases has increased as they have become viral and mixed. Viral diseases in an enclosed space called a aqua farm have a high spread rate, so it is very likely to lead to mass death. Fast identification of fish diseases is important to prevent group death. However, diagnosis of fish diseases requires a high level of expertise and it is difficult to visually check the condition of fish every time. In order to prevent the spread of the disease, an automatic identification system of diseases or fish is needed. In this paper, in order to improve the performance of the disease identification system of Paralichthys olivaceus based on deep learning, the existing pre-processing method is compared and tested. Target diseases were selected from three most frequent diseases such as Scutica, Vibrio, and Lymphocystis in Paralichthys olivaceus. The RGB, HLS, HSV, LAB, LUV, XYZ, and YCRCV were used as image pre-processing methods. As a result of the experiment, HLS was able to get the best results than using general RGB. It is expected that the fish disease identification system can be advanced by improving the recognition rate of diseases in a simple way.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.5
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• pp.30-42
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• 2022

Due to the increase in construction of tunnels, the burdens of maintenance works for tunnel structures have been increasing in Korea. In addition, the increase of traffic volume and aging of materials also threatens the safety of tunnel facilities, therefore, maintenance costs are expected to increase significantly in the future. Accordingly, automated condition assessment technologies like image-based tunnel scanning system for inspection and diagnosis of tunnel facilities have been proposed. For image-based tunnel scanning system, it is key to create a planar image through stitching of multiple images captured by tunnel scanning system. In this study, performance of feature-based stitching algorithms suitable for stitching tunnel scanning images was evaluated. In order to find a suitable algorithm SIFT, ORB, and BRISK are compared. The performance of the proposed algorithm was determined by the number of feature extraction, calculation speed, accuracy of feature matching, and image stitching result. As for stitching performance, SIFT algorithm was the best in all parts of tunnel image. ORB and BRISK also showed satisfactory performance and short calculation time. SIFT can be used to generate precise planar images. ORB and BRISK also showed satisfactory stitching results, confirming the possibility of being used when real-time stitching is required.