• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5747-5752
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• 2012

Purpose: The main objective of the present study was to evaluate the efficacy and toxicity of concurrent chemoradiotherapy followed by adjuvant chemotherapy compared with concurrent chemoradiotherapy alone in the treatment of locoregionally advanced nasopharyngeal carcinoma. Methods: The search strategy included Pubmed, Embase, the Cochrane Library, China National Knowledge Internet Web, Chinese Biomedical Database and Wanfang Database. We also searched reference lists of articles and the volumes of abstracts of scientific meetings. Randomized controlled trials (RCTs) that compared concurrent chemoradiotherapy followed by adjuvant chemotherapy with concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma were included. Meta-analysis was performed with RevMan 5.1.0. The Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to rate the level of evidence. Results: Five studies were included. Risk ratios of 1.02 (95%CI 0.89-1.15), 0.93 (95%CI 0.72-1.21), 1.07 (95%CI 0.87-1.32), 0.95 (95%CI 0.80-1.13) were observed for 3 years overall survival, 5 years failure-free survival, 5 years locoregional failure-free survival and 5 years distant metastasis failure-free survival. There were no treatment-related deaths in both groups of five studies. Hematologic and gastrointestinal toxicity were the most significant for patients during adjuvant chemotherapy. The level of evidence was low. Conclusion: Compared with concurrent chemoradiotherapy alone, concurrent chemotherapy followed by adjuvant chemotherapy did not improve prognosis. More toxicity was found during adjuvant chemotherapy.

• The Journal of Society for e-Business Studies
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• v.1 no.1
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• pp.141-157
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• 1996

Data sharing is a major challenge to implement CALS. STEP is the international standard for the product model data exchange among heterogeneous systems and plays a key role in CALS. Advances in computer networks are rapidly changing the product development processes. The network oriented modeling system premises to integrate design activities across the enterprise. To achieve goals of CALS 3-dimensional concurrent modeling that complies international standard is required since integrity and common perception of product data can be assured. This paper presents 3-dimensional concurrent geometric modeling on high speed network using STEP and methodologies.

• International Journal of Quality Innovation
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• v.8 no.2
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• pp.115-131
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• 2007

The vehicle development process (VDP) is iterative in nature with numerous interactions and information flows between design groups and between development phases. The VDP has been changed from a sequential-functional development to a concurrent-team based approach. Concurrent execution of design activities may reduce the development lead-time, but it increases the managerial complexity in the VDP. A system dynamics model was developed to understand the transient behavior of parallel, overlap, and sequential processes in the VDP and to determine the optimal level of overlapping considering the development lead-time and total number of reworks. The simulation results showed that different execution processes should be used, depending upon the intensity of reworks.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1996.04a
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• pp.689-692
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• 1996

The environment surrounded by industries is represented by the 3Cs : Customers, Competition, and Changes. The 3Cs drive industries to pursue external business targets such as customer's needs and marketplaces with BPR (Business Process Reengineering). BPR addresses core business process. One of these core business processes is product development. This product development process has been reengineered by the concept of CE (Concurrent Engineering). The aim of the paper is to build frameworks of CE to clarify the CE concept. This paper begins with investigating the product development process from the perspectives of three drivers: cost, quality and speed. CE frameworks are then followed. The first frmework is concerned with the CE definition and thus three keyphrases are extracted : from the outset, concurrent design and systematic approach. Concerned with the CE implementation, the second framework is composed of five components: generalist & specialist, cross-function team, enabling tools & techniques, success metrics, and total visibility. This paper concludes that the CE practice is hard to achieve because of the 'dont't-tell-them-early' attitude of upstream people, and the 'wait-and-see' attitude of downstream people. As resolution, a change management program is recommended that changes an employees mind-set. This paper also supposes computer systems which facilitate and keep automatic track of the CE process as engineered. Finally it gives a warning that computer systems alone do not guarantee success without being preceded by process re-engineering.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.32 no.1
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• pp.102-110
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• 2009

Concurrent Engineering(CE) has presented new possibilities for successful product development by incorporating various product life-cycle functions from the earlier stage of design. In the product design, geometric representation is vital not only in its traditional role as a means of communicating design information but also in its role as a means of externalizing designer's thought process by visualizing the design product. During the last dozens of years, there has been extraordinary development of computer-aided tools intended to generate, present or communicate 3D models. However, there has not been comparable progress in the development of 3D-CAD systems intended to represent and manipulate a variety of product life-cycle information in a consistent manner. This paper proposes a novel concept, Minus Volume (MV), to incorporate various design information relevant to product lift-cycle functions. MV is a functional shape that is extracted from a design object within a bounding box. A prototype 3D-CAD system is implemented based on the MV concept and illustrated with the successful implementation of concurrent design and manufacturing.

• Transactions of the Korean Society of Automotive Engineers
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• v.1 no.3
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• pp.83-94
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• 1993

Design and production of wiring for automobile systems provide the background for the development of concurrent engineering framwork. Key issues include with different parts of the wiring design process and the development of hierarchical representations that capture the different characteristics(e.g., connectivity, geometry) of the harnesses. The abstraction of design information results in features, while the abstraction of operations leads to the development of agents. These abstracts are essential for efficient transactions among people and computer tools in a domain that involves numerous interacting constraints. We have decomposed the wiring design process into four basic categories of tasks that are each addressed by an "agent" : the Environment Editor(EE), the Free Space Manager(FSM), the Wiring Editor(WE), and the Part Selector(PS). In this paper the strategy for the problem decomposition, the definition of features, and the ways in which features are used by various agents, are discussed. We conclude with a discussion of some of the issues raised by the project and the steps underway to address them.

• Korean Journal of Construction Engineering and Management
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• v.8 no.6
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• pp.197-206
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• 2007

The age of synthetic correspondence against "development period shortening, high quality" is about to come. While the product is becoming complexation gradually and also diversification, life cycle of product gets shorted. Under the infinity competition age, the certain answer of "the survival of the fittest" is that the enterprise itself must be able to shorten development and delivery term, reduce product development and life cycle cost, and satisfy customer in performance and value. From this point of view, concurrent engineering's theory, which develops the process of product in the manner of repetition, parallel, and synchronousness, is realized as a important strategy instrument in construction. This study investigates and analyzes several examples in order to apply concurrent engineering successfully, and presents the decision-making model through the simulation about the factor affecting in each process.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.11 no.4
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• pp.147-156
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• 2011

Though a dozen of different software life cycle models are suggested, there is no universal model which can satisfy all the characteristics of software. Organizations mix and match different life cycle models to develop a model more tailored for their systems and capabilities. We suggest overlapped-concurrent development life cycle model that is more suitable in various software development environment. Firstly, we divided the development process into abstract and implementation stage. Abstract stage is from software concept phase to detailed design starting time, and implementation stage is from detailed design phase to system testing phase. Next, the abstract stage introduced the overlapped phase concept that begins the next phase when the step is completed 20% by applying pareto's law. In the implementation stage, we introduced the concurrent development which the several phases are performed some time as when one use-case (UC) is completed the next development phase is started immediately. The proposed model has an advantage that it can reduce the inefficiency of development resource greatly. This model can increase the customer satisfaction with a great product at a low cost and on a short schedule. Also, this model can contribute to increase the software development success rate.

• IE interfaces
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• v.8 no.3
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• pp.39-45
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• 1995

제조시스템 시뮬레이션 분석과정에서 모델 검증, 엔지니어와의 커뮤니케이션 및 시뮬레이션 결과의 프리젠테이션을 위해 이제 그래픽 애니메이션은 시뮬레이터의 기본 필수 사양으로 자리잡고 있다. 본고에서는 사용자의 손쉬운 모델링 과정을 지원하는 사용자 모델러(User Modeler)와 실시간 애니메이션(Concurrent Animation) 수행을 지원하는 시뮬레이터용 애니메이션 모듈 개발에 관해 논의한다.

• Journal of Intelligence and Information Systems
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• v.1 no.1
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• pp.73-89
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• 1995

전문가시스템이 등장한지도 근 20년이 흘렀고 다양한 분야에서 기업의 중추적 시스템으로 운영되고 있다. 이렇게 전문가시스템이 연구단계에서 벗어나 실용화됨에 따라 전문가시스템의 개발방법에 대한 연구가 학계가 산업계가 새로운 연구과제로 인식되고 있다. 지금까지 개발에 대한 연구는 주로 지식획득 기술의 개발에 치중되어있다. 본 논문에서는 전문가시스템의 개발에 대한 방법론적 접근방법이 제시된다. 이 접근벙법은 시간과 인력 등 자원의 제약을 받는 전문가시스템 개발프로젝트에 적합한 것으로 동시공학(Concurrent Engineering)개념을 채택하고 있으며 개발 라이프사이클 모델, 프로젝트팀 구성방법등을 다루고 있다. 또한, 동시공학적 접근방법을 지원하기 위한 분석과 설계방법으로는 객체지향기술을 사용하며 개발단계별로 해당 모델이 산출물로 구축된다.