Purpose : This study is a descriptive correlation study to offer the basic materials for developing the preventive program of continuously increasing AIDS in the young people by examining the knowledge and attitude of AIDS in college students. Methods : The period of data collection was from May 1 to 15, 2009, 300 freshman, sophomore and junior students who understood the purpose of the research and agreed to participate in the questionnaire were randomly sampled, structured questionnaire was distributed to them and their responses were collected. Instruments used for this study included those used by Kim and Lee and revised and complemented by this researcher to measure the knowledge of AIDS and those by Yun and Lee revised and complemented by the researcher to measure the attitude of AIDS. For data analysis, it measured technical statistics, t-test, ANOVA, and Pearson's correlation coefficient using SPSS/PC 12.0. Results : The results of this study are summarized as follows. 1. The whole knowledge of AIDS the subjects had scored 58.9 and their average attitude scored $3.78(1{\pm}25)$. 2. In the degree of knowledge of AIDS depending on general characteristics and health-related characteristics of the subjects, it was found that the students at the department of emergency medical showed higher knowledge(t=3.638, p=.001) and positive attitude of AIDS(t=3.330, p=.001) compared to students at other majors. 3. In the degree of knowledge of AIDS depending on AIDS-related education, subjects who had experienced AIDS education(t=1.973, p=.050), those with the experience of theory education(F=4.057, p=.008), those who felt the necessity of AIDS education(t=4.588, p=.000), and those who were willing to take part in AIDS education(t=2.898, p=.004) showed higher know1edge of AIDS. In the attitude of AIDS, subjects with theory-oriented AIDS education(F=3.012, p=.032), those who felt the necessity of AIDS education(t=2.445, p=.015), and those who were willing to take part in AIDS education(t=2.379, p=.018) showed positive attitude of AIDS education. 4. As the knowledge of AIDS the subjects was higher(r=.329, p=.000), they showed more positive attitude of AIDS and it meant that there was positive correlations. Conclusion : Consequently, systematic, concrete and continuous education of AIDS suitable to the requirements of college students is needed to induce changes of their knowledge and attitude of AIDS and for this, AIDS education program which can be used properly by the developmental stages of college students who belong to late adolescence should be developed in the field of school and if possible, curriculum of sex education including AIDS education should be established in all departments of college.