• Title/Summary/Keyword: Conclusion Similarity

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Position of Hungarian Merino among other Merinos, within-breed genetic similarity network and markers associated with daily weight gain

  • Attila, Zsolnai;Istvan, Egerszegi;Laszlo, Rozsa;David, Mezoszentgyorgyi;Istvan, Anton
    • Animal Bioscience
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    • v.36 no.1
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    • pp.10-18
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    • 2023
  • Objective: In this study, we aimed to position the Hungarian Merino among other Merinoderived sheep breeds, explore the characteristics of our sampled animals' genetic similarity network within the breed, and highlight single nucleotide polymorphisms (SNPs) associated with daily weight-gain. Methods: Hungarian Merino (n = 138) was genotyped on Ovine SNP50 Bead Chip (Illumina, San Diego, CA, USA) and positioned among 30 Merino and Merino-derived breeds (n = 555). Population characteristics were obtained via PLINK, SVS, Admixture, and Treemix software, within-breed network was analysed with python networkx 2.3 library. Daily weight gain of Hungarian Merino was standardised to 60 days and was collected from the database of the Association of Hungarian Sheep and Goat Breeders. For the identification of loci associated with daily weight gain, a multi-locus mixed-model was used. Results: Supporting the breed's written history, the closest breeds to Hungarian Merino were Estremadura and Rambouillet (pairwise FST values are 0.035 and 0.036, respectively). Among Hungarian Merino, a highly centralised connectedness has been revealed by network analysis of pairwise values of identity-by-state, where the animal in the central node had a betweenness centrality value equal to 0.936. Probing of daily weight gain against the SNP data of Hungarian Merinos revealed five associated loci. Two of them, OAR8_17854216.1 and s42441.1 on chromosome 8 and 9 (-log10P>22, false discovery rate<5.5e-20) and one locus on chromosome 20, s28948.1 (-log10P = 13.46, false discovery rate = 4.1e-11), were close to the markers reported in other breeds concerning daily weight gain, six-month weight, and post-weaning gain. Conclusion: The position of Hungarian Merino among other Merino breeds has been determined. We have described the similarity network of the individuals to be applied in breeding practices and highlighted several markers useful for elevating the daily weight gain of Hungarian Merino.

Automated Lung Segmentation on Chest Computed Tomography Images with Extensive Lung Parenchymal Abnormalities Using a Deep Neural Network

  • Seung-Jin Yoo;Soon Ho Yoon;Jong Hyuk Lee;Ki Hwan Kim;Hyoung In Choi;Sang Joon Park;Jin Mo Goo
    • Korean Journal of Radiology
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    • v.22 no.3
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    • pp.476-488
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    • 2021
  • Objective: We aimed to develop a deep neural network for segmenting lung parenchyma with extensive pathological conditions on non-contrast chest computed tomography (CT) images. Materials and Methods: Thin-section non-contrast chest CT images from 203 patients (115 males, 88 females; age range, 31-89 years) between January 2017 and May 2017 were included in the study, of which 150 cases had extensive lung parenchymal disease involving more than 40% of the parenchymal area. Parenchymal diseases included interstitial lung disease (ILD), emphysema, nontuberculous mycobacterial lung disease, tuberculous destroyed lung, pneumonia, lung cancer, and other diseases. Five experienced radiologists manually drew the margin of the lungs, slice by slice, on CT images. The dataset used to develop the network consisted of 157 cases for training, 20 cases for development, and 26 cases for internal validation. Two-dimensional (2D) U-Net and three-dimensional (3D) U-Net models were used for the task. The network was trained to segment the lung parenchyma as a whole and segment the right and left lung separately. The University Hospitals of Geneva ILD dataset, which contained high-resolution CT images of ILD, was used for external validation. Results: The Dice similarity coefficients for internal validation were 99.6 ± 0.3% (2D U-Net whole lung model), 99.5 ± 0.3% (2D U-Net separate lung model), 99.4 ± 0.5% (3D U-Net whole lung model), and 99.4 ± 0.5% (3D U-Net separate lung model). The Dice similarity coefficients for the external validation dataset were 98.4 ± 1.0% (2D U-Net whole lung model) and 98.4 ± 1.0% (2D U-Net separate lung model). In 31 cases, where the extent of ILD was larger than 75% of the lung parenchymal area, the Dice similarity coefficients were 97.9 ± 1.3% (2D U-Net whole lung model) and 98.0 ± 1.2% (2D U-Net separate lung model). Conclusion: The deep neural network achieved excellent performance in automatically delineating the boundaries of lung parenchyma with extensive pathological conditions on non-contrast chest CT images.

Determination of the Optimum Sampling Area for the Benthic Community Study of the Songdo Tidal Flat and Youngil Bay Subtidal Sediment (송도 갯벌과 영일만 조하대 저서동물의 군집조사를 위한 적정 채집면적의 결정)

  • Koh, Chul-Hwan;Kang, Seong-Gil;Lee, Chang-Bok
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.4 no.1
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    • pp.63-70
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    • 1999
  • The optimum sampling area which can be applied to the benthic community study is estimated from large survey data in the Songdo tidal flat and subtidal zone of Youngil Bay, Korea. A total of 250 samples by 0.02 $m^2$ box corer for the benthic fauna in Songdo tidal flat and 50 samples by 0.1 $m^2$ van Veen grab in Youngil Bay were taken from the total sampling area of 5 $m^2$. It was assumed that the sampling area could contain sufficient information on sediment fauna, if cumulative number of species, ecological indices, and similarity index by cluster analysis reflect the similarity level of 75% to those found at total sampling area (5 $m^2$). A total of 56 and 60 species occurred from Songdo tidal flat and Youngil Bay, respectively. The cumulative curve of the species number ($N_{sp}$) as a function of the sampling area (A in $m^2$ ) was fitted as $N_{sp}=37.379A^{0.257}$ ($r^2=0.99$) for intertidal fauna and $N_{sp}=40.895A^{0.257}$ ($r^2=0.98$) for subtidal fauna. Based on these curves and 75% of similarity to the total sampling area (5 $m^2$), the optimum sampling area was proposed as 1.6 $m^2$ for the intertidal and 1.5 $m^2$ for the subtidal fauna. Ecological indices (species diversity, richness, evenness and dominance indices) were again calculated on the basis of species composition in differently simulated sample sizes. Changes in ecological indices with these sample sizes indicated that samplings could be done by collecting fauna from < 0.5 $m^2$-1.5 $m^2$ on the Songdo tidal flat and from < 0.5 $m^2$-1.2 $m^2$ in Youngil Bay. Changes in similarity level of all units of each simulated sample size showed that sampling area of 0.3 $m^2$ (Songdo tidal flat) and 0.6 $m^2$ (Youngil Bay) should be taken to obtain a similarity level of 75%. In conclusion, sampling area which was determined by cumulative number of species, ecological indices and similarity index by cluster analysis could be determined as 1.5 $m^2$ (0.02 $m^2$ box corer, n=75) for Songdo tidal flat and 1.2 $m^2$ (0.1 $m^2$ van Veen grab, n=12) for Youngil Bay. If these sampling areas could be covered in the field survey, population densities of seven dominant species comprising 68% of the total faunal abundance occurring on Songdo tidal flat and six species comprising 90% in Youngil Bay can be estimated at the precision level of P=0.2.

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A Study on 'Eco-Look' expressed in contemporary fashion (현대패션에 표현된 에콜로지에 관한 연구)

  • 정연자
    • Journal of the Korean Society of Costume
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    • v.30
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    • pp.227-237
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    • 1996
  • The purpose of this study is to investigate the main characteristics of the environmentalism expressed in contemporary fashion. i.e. 'eco-look'. They can be categorized into naturalism symbolism primitiveness and concern about recycling. First naturalistic tendency can be found in through the method of some contemporary eco-looks which are using natural colors harmonisation of the colors in similarity and in controst and expressing in a realistic manner some natural entities or use some ornaments representing them. Such trends easily let people to feel the clothes unified with the nature and human beings. Secondly some contemporary eco-looks express environmentalistic ideas for examples the idea for protection of the nature or the idea against pollution of the earth and destruction of nature in a symbolistic way. Thirdly primitiveness is one of the most characteristic feature in contemporary eco-looks. It can be found in contemporary eco-looks, In can be found in some eco-looks using primitive or original images of Africa and underdeveloped countries. it reflects the human desire to go back to the nature or to the unity with the nature, Finally recycled materials are commonly used in eco-look. Patchwork and handmade knits are popular methods for this mode. They implicates the idea of pragmatism and simplicity in fashion. One Conclusion of the paper on eco-look: fashion design which can be itself an import-ant environment of human beings Secondly some contemporary eco-looks ex-press environmentalistic ideas for examples the idea for protection of the nature or the idea against pollution of the earth and destruction of nature in a symbolistic way. Thirdly primitiveness is one of the most characteristic feature in contemporary eco-looks. It can be found in some eco-looks using primitive or original images of Africa and underdeveloped countries. it reflects the human desire to go back to the nature or to the unity with the nature. Finally recycled materials are commonly used In eco-look Patchwork and handmade knits are popular methods for this mode. They implicates the idea of pragmatism and simplicity in fashion. One Conclusion of the paper on eco-look ; fashion design which can be itself an import-ant environment of human beings has become a very efficient and significant tool to express the idea of ecology.

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The Study of Standard Deviation of Gray Scale Histogram in Digital Subtraction Radiography as a Test Parameter for SuperimpoSition Error (중첩 불일치 평가기준으로서의 계수공제영상의 계조도 표준편차 연구)

  • Cho Bong-Hae
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.29 no.2
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    • pp.417-422
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    • 1999
  • Purpose : The aim of this study was to assess the validity of standard deviation of gray scale histogram in digital subtraction radiography as a test parameter for superimposition error. Materials and Methods : Twenty periapical radiographs were used as baseline images and they were copied to exclude the influence of exposure geomety and contrast differences. These subsequent images were linearly displaced by 0.1-0.5 mm in the x-. y- and xy-directions, rotated by 0.5-3° and distorted by angular contraction of 1-5° in x- and y-axis before subtraction. The standard deviations of gray levels in the subtraction images were obtained and paired t-tests were performed. Pearson correlation coefficients(r) were calculated between the standard deviations and the superimposition errors. Results : Linear displacement showed high correlation coefficients of 0.997, 0.997 and 0.995 in x-. y- and xy-axis respectively. Statistically significant different standard deviation existed among all linearly displaced groups(p<0.05). Distortion showed relatively low correlation coefficients of 0.982 and 0.959 in x- and y-axis. The standard deviations between the two distortion groups were statistically significant different(p<0.05). Conclusion : Standard deviation of gray level distribution in digital subtraction images is satisfactory but not perfect similarity measure to assess the superimposition errors.

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Categorizing accident sequences in the external radiotherapy for risk analysis

  • Kim, Jonghyun
    • Radiation Oncology Journal
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    • v.31 no.2
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    • pp.88-96
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    • 2013
  • Purpose: This study identifies accident sequences from the past accidents in order to help the risk analysis application to the external radiotherapy. Materials and Methods: This study reviews 59 accidental cases in two retrospective safety analyses that have collected the incidents in the external radiotherapy extensively. Two accident analysis reports that accumulated past incidents are investigated to identify accident sequences including initiating events, failure of safety measures, and consequences. This study classifies the accidents by the treatments stages and sources of errors for initiating events, types of failures in the safety measures, and types of undesirable consequences and the number of affected patients. Then, the accident sequences are grouped into several categories on the basis of similarity of progression. As a result, these cases can be categorized into 14 groups of accident sequence. Results: The result indicates that risk analysis needs to pay attention to not only the planning stage, but also the calibration stage that is committed prior to the main treatment process. It also shows that human error is the largest contributor to initiating events as well as to the failure of safety measures. This study also illustrates an event tree analysis for an accident sequence initiated in the calibration. Conclusion: This study is expected to provide sights into the accident sequences for the prospective risk analysis through the review of experiences.

Research on Technopark Management Performance Comparison Based on National Quality Awards Appraisal Standard by Countries (국가별 국가품질상 평가기준에 따른 테크노파크 경영실적 비교 연구)

  • Hwang, Sung-Taek;Park, Jong-Woo
    • Journal of Korean Society for Quality Management
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    • v.40 no.4
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    • pp.497-512
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    • 2012
  • Purpose: Most major countries have their own set of qualifications called national quality awards to measure the quality of companies and organizations. This study analyzes 3 different national quality awards and compare with the result from Korean quality awards conducted by Ministry of knowledge and Economy and Korea institute for advancement of technology. Methods: We tested 17 technoparks out of 18 technoparks in Korea and see how different the results can be depends on the value weights. We closely looked at each qualifications and tables of different countries' awards and compared with one used in Korea. Finally we proposed some suggestions to use not only domestic model but also international ones to be objective and add efficiency to organizations. Results: Depend on similarity of qualifications and weights, there were countries with different results and these caused score and ranking changes. Nevertheless, there was a comparison that did not make any changes on both score and ranking. Conclusion: We recognized the limitation that a standardized quality variation cannot be enough sources to test and analyze technoparks with different size and criteria. Integrating global standards and flow would be the first step to help grow technoparks and organizations placed in Korea in days to come.

Effects of steaming on saponin compositions and antiproliferative activity of Vietnamese ginseng

  • Le, Thi Hong Van;Lee, Seo Young;Lee, Gwang Jin;Nguyen, Ngoc Khoi;Park, Jeong Hill;Nguyen, Minh Duc
    • Journal of Ginseng Research
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    • v.39 no.3
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    • pp.274-278
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    • 2015
  • Background: Steaming of ginseng is known to change its chemical composition and biological activity. This study was carried out to investigate the effect of different steaming time-scales on chemical constituents and antiproliferative activity of Vietnamese ginseng (VG). Methods: VG was steamed at $105^{\circ}C$ for 2-20 h. Its saponin constituents and antiproliferative activity were studied. The similarity of chemical compositions between steamed samples at $105^{\circ}C$ and $120^{\circ}C$ were compared. Results: Most protopanaxadiol and protopanaxatriol ginsenosides lost the sugar moiety at the C-20 position with 10-14 h steaming at $105^{\circ}C$ and changed to their less polar analogues. However, ocotillol (OCT) ginsenosides were reasonably stable to steaming process. Antiproliferative activity against A549 lung cancer cells was increased on steaming and reached its plateau after 12 h steaming. Conclusion: Steaming VG at $105^{\circ}C$ showed a similar tendency of chemical degradation to the steaming VG at $120^{\circ}C$ except the slower rate of reaction. Its rate was about one-third of the steaming at $120^{\circ}C$.

The benefit of one cannot replace the other: seagrass and mangrove ecosystems at Santa Fe, Bantayan Island

  • Mendoza, Ayana Rose R.;Patalinghug, Jenny Marie R.;Divinagracia, Joshua Ybanez
    • Journal of Ecology and Environment
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    • v.43 no.2
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    • pp.183-190
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    • 2019
  • Background: In the Philippines, the practice of planting mangroves over seagrass has been a practice done to promote coastline protection from damages done by storms. Despite the added protection to the coastline, the addition of an artificial ecosystem gradually inflicts damage to the ecosystem already established. In this study, seagrass communities that had no history of mangrove planting were compared with those that had mangrove planting. The percent substrate cover of seagrass in the sampling areas was determined, and the macroinvertebrates present in the sampling areas were also observed. The study was conducted based on reports of mangrove planting activity that disrupted seagrass functions on Santa Fe, Bantayan Island, Cebu. Transect-quadrat method sampling was done to assess the chosen sites. Results: Six species of seagrass was found on the site without mangrove planting which was barangay Ocoy (Cymodocea sp., Thalassia sp., Halodule sp., Enhalus sp., Halophila sp., and Syringodium sp.) and had a higher percent cover, while only four were found on the site with mangrove planting (barangay Marikaban). It was also found that barangay Marikaban had a lesser Shannon-Wiener and Simpson's index compared to barangay Ocoy. Jaccard's index of similarity between the two sites was low. Conclusion: With the results of the assessment, we recommend proper monitoring of future mangrove planting activities and that these activities should not disrupt another ecosystem as all ecosystems are important.

Assessment of Degree of Naturalness of Vegetation on the Riverine Wetland (하천습지의 식생학적 자연도 평가)

  • Chun, Seung-Hoon
    • Journal of Environmental Impact Assessment
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    • v.20 no.1
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    • pp.1-11
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    • 2011
  • This study was carried out to suggest the baseline data necessary for vegetation restoration at riverine wetland within stream corridor. We used the prevalence index for wetland assessment by applying the method of weighted averages with index values based on five hydrophyte indicator status as defined by estimated probability occurred in wetland. We selected near nature and urbanized reach of Gap and Yanghwa streams as experimental site. Although two sites have some different disturbance and characteristics of watershed, they showed that similarity of vegetation community including three dominant species - Salix koreensis, Phragmites communis, Miscanthus sacchariflorus - was very high. But in case of Yanghwa stream, various kinds of emergent plants along wetted condition were distinctly occurred, resulted from difference of hydrological regime and substrate, etc. Degree of naturalness of vegetation at the sampled areas indicated that near nature area of Gap stream and all area of Yanghwa stream were fitted as riverine wetland, while urbanized area of Gap stream has changed into upland condition. In conclusion assessment system using prevalence index would be considered an effective method for evaluating of natural states of riverine wetland, but further integrated consideration of physical, hydrological, and biological factors of stream process, and also with considering the difference between those qualitative data of vegetation community.