• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.915-921
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• 2012

Background: Previous studies investigating the association between TP53 Arg72Pro polymorphism and gastric cancer (GC) risk in Asian population have reported controversial results. Thus, a meta-analysis was performed. Methods: A comprehensive literature search was conducted and 17 case-control studies were finally included, involving a total of 5,990 GC cases and 6,812 controls. Subgroup analyses were performed by the sample size. Results: Meta-analysis of all 17 studies showed variant genotypes of TP53 Arg72Pro to be associated with an elevated GC risk in three genetic comparison models ($OR_{Pro\;vs.\;Arg}$=1.13, 95%CI 1.03-1.25, $P_{OR}$=0.01; $OR_{Homozygote\;comparison\;model}$=1.33, 95%CI 1.07-1.64, $P_{OR}$=0.009; $OR_{Dominant\;genetic\;model}$=1.13, 95%CI 1.05-1.22, $P_{OR}$=0.002). Besides, a more obvious association was observed after the heterogeneity was decreased (all P values less than 0.001). This association was further identified by both subgroup and sensitivity analyses. Conclusions: This meta-analysis suggests the Pro variant of TP53 Arg72Pro contributes to gastric cancer risk in Asians.

• Journal of the Korean Society of Physical Medicine
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• v.19 no.1
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• pp.43-51
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• 2024

PURPOSE: Sarcopenic obesity (SO) is a clinical condition that combines sarcopenia and obesity. This study examined the frequency of SO in young Korean females between 20 and 29 years of age. METHODS: The study involved 1,000 participants. The height, weight, body mass index (BMI), waist circumference, skeletal muscle mass index, fasting glucose, triglyceride, total cholesterol levels, systolic and diastolic blood pressure, alcohol consumption, and smoking status were the research variables. The skeletal muscle mass index was calculated as appendicular skeletal muscle mass (ASM) divided by the BMI. The ASM was assessed using dual X-ray absorptiometry. Complex sampling analysis and multiple logistic regression were used for analysis. RESULTS: A .74(.30-1.80) frequency of SO was observed. The statistically significant risk factors in females were height, weight, BMI, waist circumference, skeletal muscle mass index, total cholesterol, systolic blood pressure, and diastolic blood pressure (p < .05). CONCLUSION: Young Korean adults with SO have a .74(.30-1.80) frequency of occurrence that is linked to specific risk factors. Hence, primary care clinicians and health care professionals should consider these factors when patients require a referral for early detection and treatment. Healthcare professionals and clinicians can identify potential SO patients by acknowledging these risk factors.

• Research in Community and Public Health Nursing
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• v.28 no.2
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• pp.206-215
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• 2017

Purpose: This study aimed to verify the predictive validity of Comprehensive Korean Frailty Instrument (CKFI) among older adults. Methods: A secondary analysis of data from a prospective cohort study was conducted. Frailty was determined in older adults (N=9,188) according to the data in 2008 and the effects of frailty on adverse outcomes (such as institutionalization and death) were evaluated according to the data in 2011. The Cardiovascular Health Study (CHS) index was used to compare with the predictive validity of CKFI. Results: The prevalence of frailty was 26.3%. With the CKFI, the frail group had a higher risk of negative health outcomes compared to the robust and pre-frail groups after three years. The two of the highest risks identified using the CKFI and CHS index were institutionalization (5.522 times higher) and mortality (3.210 times higher). For both instruments, the survival analysis revealed that the risk of death increased as the degree of frailty increased. Conclusion: The CKFI consisting of self-report items and multidimensional aspects of frailty can be used as a simple instrument for assessing the frailty of older adults residing in a local community in Korea.

• Proceedings of the Korean Society of Disaster Information Conference
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• 2022.10a
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• pp.148-149
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• 2022

본 논문에서는 지역별로 발생 양상이 다른 사회재난의 종합적 위험분석을 위한 정보활용 방안 및 전략을 제안한다. 사회재난은 재난유형이 매우 다양하며, 각기 다른 발생 및 전파양상을 가지고 있어 전문성을 기반으로 관계하고 있는 개별부처에서 각각 관리되고 있다. 재난이 발생 후 대응, 수습 및 복구에 이르는 활동은 대표적인 현장대응 부처인 행정안전부, 경찰청, 소방청 등에서 주로 담당하고 있으나, 예방 및 대비 활동은 각 부처에서 개별법령에 의한 제도 및 정책에 의해 위험요소를 저감하기 위한 활동으로 진행된다. 예를 들어 화학사고의 경우 화학사고예방관리계획서, 장외영향평가, 화재는 방화지구, 화재경계지구, 산불은 산불취약지수 등 각각의 물리적 매커니즘을 적정히 고려하는 이론적 근거의 의해 사전에 그 위험을 평가하고 있으나 재난관리 예방을 담당하는 부처에 까지 연속성을 가지고 그 결과들이 적극적으로 활용되고 있지 못하고 있다. 이에 본 연구에서는 각 부처에서 개별법령에 의해 평가되는 공신력 있는 자료들의 융합적 해석에 근거한 종합위험 평가 개념을 정립하고 실제 활용 가능성에 대해 논하고자 한다.

• Journal of Chest Surgery
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• v.57 no.2
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• pp.195-204
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• 2024

Background: Extracorporeal membrane oxygenation (ECMO) is an intervention for severe heart and lung failure; however, it poses the risk of complications, including gastrointestinal bleeding (GIB). Comprehensive analyses of GIB in patients undergoing ECMO are limited, and its impact on clinical outcomes remains unclear. Methods: This retrospective study included 484 patients who received venovenous and venoarterial ECMO between January 2015 and December 2022. Data collected included patient characteristics, laboratory results, GIB details, and interventions. Statistical analyses were performed to identify risk factors and assess the outcomes. Results: GIB occurred in 44 of 484 patients (9.1%) who received ECMO. Multivariable analysis revealed that older age (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01-1.06; p=0.0130) and need to change the ECMO mode (OR, 3.74; 95% CI, 1.75-7.96; p=0.0006) were significant risk factors for GIB, whereas no association was found with antiplatelet or systemic anticoagulation therapies during ECMO management. Half of the patients with GIB (22/44, 50%) underwent intervention, with endoscopy as the primary modality (19/22, 86.4%). Patients who underwent ECMO and developed GIB had higher rates of mortality (40/44 [90.9%] vs. 262/440 [59.5%]) and ECMO weaning failure (38/44 [86.4%] vs. 208/440 [47.3%]). Conclusion: GIB in patients undergoing ECMO is associated with adverse outcomes, including increased risks of mortality and weaning failure. Even in seemingly uncomplicated cases, it is crucial to avoid underestimating the significance of GIB.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.1
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• pp.29-41
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• 2018

These days, corporate risk management has become a major concern in the corporate world. Companies in the global environment are exposed to diverse kinds of risks that are affecting the decisions of investors and other stakeholders. Therefore, companies are expected to not only identify and manage risks but also voluntarily report the same to the stakeholders. Increasingly, standard setters and regulators are requiring firms to disclose such information. On the contrary, there also exists a perception that risk reporting can create a negative impression among the stakeholders about the future of the company. In line with such growing dilemma for risk disclosures, the issue of corporate risk reporting (CRR) has been receiving immense emphasis from the accounting academicians. The main objective of this article is to conduct a comprehensive literature review on corporate risk disclosures. In order to fulfill this objective, at first, a summary of the relevant available literature is presented to identify the current regulations on risk reporting, existing trends of CRR research and theories applied in research. Then, through analysis, several research avenues are identified. It is expected that if these dimensions are explored by the future researchers, a better and broader understanding of the risk reporting practices can be achieved.

• Geomechanics and Engineering
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• v.28 no.6
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• pp.573-584
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• 2022

Water inrush may occur during seaside urban tunnel excavation. Various factors affect the water inrush, and the water inrush mechanism is complex. In this study, nine evaluation indices having potential effects on water inrush were analysed. Specifically, the geographic and geomorphic conditions, unfavourable geology, distance from the tunnel to sea, strength of the surrounding rock, groundwater level, tidal action, cyclical footage, grouting pressure, and grouting reinforced region were analysed. Furthermore, a two-step interval risk assessment method for water inrush management during seaside urban tunnel excavation was developed by a multi-index system and interval risk assessment comprised of an interval analytic hierarchy process, fuzzy comprehensive evaluation, and relative superiority analysis. The novel assessment method was applied to the Haicang Tunnel successfully. A preliminary interval risk assessment method for water inrush was performed based on engineering geological conditions. As a result, the risk level fell into a risk level IV, which represents a section with high risk. Subsequently, a secondary interval risk assessment method was performed based on engineering geological conditions and construction conditions. The risk level of water inrush is reduced to a risk level II. The results agreed with the current tunnel situation, which verified the reliability of this approach.

• Fire Science and Engineering
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• v.15 no.4
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• pp.1-9
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• 2001

The purpose of this study is to set up disaster prevention plan and risk assessment system considering combustion velocity at traditional housing zone. The combustion velocity analysis could contribute to build in disaster prevention technique through the potential risk analysis of the area, such analysis also able to set up comprehensive disaster prevention management system. Following results have achieved through the combustion velocity calculation. \circled1 The combustion velocity was calculated in order of the below winds, the above winds and the side winds. \circled2 It must be careful to set up disaster prevention plan in case of the below winds. \circled3 The combustion velocity was calculated at the density Bone where neighboring Distance and Length was small. \circled4 It proved that factors of each parameter not mostly effect to analyse the combustion velocity in limit of the 30 minutes after ignition. \circled5 At the density zone where Distance and Length is small the duration of transfer to neighboring house takes up to 4 minutes, it is required to set up of emergency response plan to minimize the fire dispersion.

• Journal of Korean Academy of Nursing
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• v.43 no.3
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• pp.341-351
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• 2013

Purpose: This study was done to analyze the effects of Tai Chi on fall-related risk factors through meta-analysis of randomized clinical trials published in English and Korean between 2000 and 2010. Methods: Using health related database and hand search of references and Google, 28 randomized studies were collected from doctoral dissertation and published peer reviewed articles. The Comprehensive Meta-analysis version 2.0 was used for the analysis. Results: The effect sizes for Tai Chi for 3 months were significant with ES=0.54 for static balance, ES=0.24 for dynamic balance, ES=0.69 for balance measured by scale, and ES=0.40 for flexibility, ES=0.48 for muscle strength, ES=0.71 for ADL, and ES=0.37 for fear of falling. Also, the effect sizes of Tai Chi for 6 months were significant for most fall-related variables. The 6 month data for flexibility was not analyzed since only one study was published. Conclusion: The analysis of studies of randomized clinical trials indicate that Tai Chi is effective in improving balance, flexibility, muscle strength, activities of daily living, and fear of falling when applied for 3 or 6 months. The findings provide the objective evidence to apply Tai Chi as a fall preventive intervention.

• Korean Journal of Human Ecology
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• v.24 no.3
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• pp.341-358
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• 2015

This study aims to identify predictors of driving cessation among Korean elderly. Data from 2011 Elderly Survey conducted by Ministry of Health and Welfare and Korea Institute for Health and Social Affairs were used for the analysis. Based on Webber, Porter, Menec(2010)'s comprehensive theoretical framework for mobility, the model of this study tests five major determinants of driving cessation including financial, psychosocial, environmental, physical and cognitive factors. Results of logistic regression analysis showed that economic status, marital status, contacts with relatives and friends, residential location, taking medication, muscle strength, age, gender, and job were significant predictors of driving cessation of older drivers. Specifically, lower economic status, unmarried status, less contacts with relatives and friends, living in the city, taking medication, weaker muscle strength, older age, female, non-working status were significant risk factors for driving cessation. Practical implications in light of study findings were discussed.