• Journal of Korean Society for Atmospheric Environment
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• v.21 no.1
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• pp.97-105
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• 2005

In order to reduce the uncertainties and improve the air flow field, objective analysis using asynoptic observational data is chosen as a method that enhances the reality of meteorology. In surficial data and their numerical interpolation for improving the interpretation of meteorological components, objective analysis scheme should perform a smooth interpolation, detect and remove the bad data and carry out internal consistency analysis. For objective analysis technique which related to data reliability and error suppression, we carried out two quality control methods. In site quality control, asynoptic observational data at urban area revealed low representation by the complex terrain and buildings. In case of wind field, it was more effective than temperature field when it were interpolated near waterbody data. Many roads, buildings, subways, vehicles are bring about artificial heat which left out of consideration on the simulation of air flow field. Therefore, in temperature field, objective analysis for more effective result was obtained when surficial data were interpolated as many as possible using value quality control rather than the selection of representative site.

• Tuberculosis and Respiratory Diseases
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• v.55 no.6
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• pp.570-578
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• 2003

Background : Ambient particles during Asian dust events are usually sized less than $10{\mu}m$, known to be associated with the adverse effects on the general populations. But, there has been no considerable evidence linking these particles to the adverse effects on airways. The objectives of this study was to investigate the possible adverse effects of Asian dust events on respiratory function and symptoms in subjects with bronchial asthma. Patients and Methods : From march to June 2002, Asthmatic patients who were diagnosed with bronchial challenge test or bronchodilator response were enrolled. We divided them into three groups; mild, moderate, and severe, according to the severity. Subjects with other organ insufficiency such as heart, kidney, liver, and malignancy were excluded. All patients completed twice daily diaries and recorded peak flow rate, respiratory symptom, and daily activity. Daily and hourly mean pollutant levels of particulate matter < $10{\mu}m$ in diameter($PM_{10}$), nitrogen dioxide($NO_2$), sulphur dioxide($SO_2$), ozone($O_3$) and carbon monoxide(CO) were measured at the 10 different monitoring sites. Results : Dust events occured 14 times during the study period. Daily averages of 4 air pollutant were measured with an increased level of $PM_{10}$, decreased level of $NO_2$ and $SO_2$, and no change in CO during dust days compared to those during control days. An increase in $PM_{10}$ concentration was associated with an increase of subjects with PEF variability of >20% (p<0.05), night time symptom(p<0.05), and a decrease in mean PEF (p<0.05), which were calculated by the longitudinal data analysis. Otherwise, there was no association between $PM_{10}$ level and bronchodialtor inhaler, and daytime respiratory symptoms. Conclusion : This study shows evidence that ambient air pollution, especially $PM_{10}$, during Asian dust events, could be one of the many aggravating factors at least in patients with airway diseases. This data can be used as a primary source to set up a new policy on air environmental control and to evaluate the safety of air pollution index. We also expect that this research will help identify precise components of dust, which are more linked to the adverse effects.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.273-276
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• 1996

In the Total Artificial Heart (TAH) and Ventricular Assist Device (VAD), the size implanting the internal controller into human body is very serious problem. Hence, we need the size reduction of that controller for safe implantation. Using PSD302 chip for microcontroller-based applications, we could decrease the number of components in the digital control board and miniaturize the digital control board. We could replace a ROM, RAM, and a latch with that single chip, so the size of the newly developed board could be half the previous board.

• Journal of Communications and Networks
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• v.18 no.4
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• pp.540-550
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• 2016

Since energy efficiency has become a significant concern for network infrastructure, next-generation network devices are expected to have embedded advanced power management capabilities. However, how to effectively exploit the green capabilities is still a big challenge, especially given the high heterogeneity of devices and their internal architectures. In this paper, we introduce a hierarchical power management architecture (HPMA) which represents physical components whose power can be monitored and controlled at various levels of a device as entities. We use energy aware state (EAS) as the power management setting mode of each device entity. The power policy controller is capable of getting information on how many EASes of the entity are manageable inside a device, and setting a certain EAS configuration for the entity. We propose the optimal local control policy which aims to minimize the router power consumption while meeting the performance constraints. A first-order Markov chain is used to model the statistical features of the network traffic load. The dynamic EAS configuration problem is formulated as a Markov decision process and solved using a dynamic programming algorithm. In addition, we demonstrate a reference implementation of the HPMA and EAS concept in a NetFPGA frequency scaled router which has the ability of toggling among five operating frequency options and/or turning off unused Ethernet ports.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.23 no.8
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• pp.2064-2071
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• 1998

A new digital clock level translator has been designed in order to produce a clock source of the internal logic circuits. The translator output has 50% duty ratio from small sinusoidal input such as TCXO which oscillates itself in poratable components. The circuit consists of positive and negative comparators, RS latch, charge pump, and reference vol- tage generator. It detects pulse width of the output waveform and feedbacks the control signal to the input com-parator. It detects pulse width of the output waveform and feedbacks the control signal to the input com-parator reference, producing output waveform with valid 50% duty ratio of the digital signal level. The designed level translator can be used as a sampling clock source of ADC, PLL and the colck source of the clock synthesizer. The circuit wasdesigned in a 0.8.mu.m analog CMOS technology with double metal, double poly, and BSIM3 circuit simulation model. From our experimental results, a stable operating characteristics of 50 +3% duty ratio was obtained from the sinusoidal input wave of 370 mV.

• Journal of Korean Academy of Nursing
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• v.52 no.5
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• pp.535-549
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• 2022

Purpose: The study aimed to design and develop an automated personalized self-care (APSC) program for patients with type 2 diabetes mellitus. The secondary aim was to present a clinical protocol as a mixed-method research to test the program effects. Methods: The APSC program was developed in the order of analysis, design, implementation, and evaluation according to the software development life cycle, and was guided by the self-regulatory theory. The content validity, heuristics, and usability of the program were verified by experts and patients with type 2 diabetes mellitus. Results: The APSC program was developed based on goal setting, education, monitoring, and feedback components corresponding to the phases of forethought, performance/volitional control, and self-reflection of self-regulatory theory. Using the mobile application, the participants are able to learn from educational materials, monitor their health behaviors, receive weekly-automated personalized goals and feedback messages, and use an automated conversation system to solve the problems related to self-care. The ongoing two-year study utilizes a mixed method design, with 180 patients having type 2 diabetes mellitus randomized to receive either the intervention or usual care. The participants will be reviewed for self-care self-efficacy, health behaviors, and health outcomes at 6, 12, 18, and 24 months. Participants in the intervention group will be interviewed about their experiences. Conclusion: The APSC program can serve as an effective tool for facilitating diabetes health behaviors by improving patients' self-care self-efficacy and self-regulation for self-care. However, the clinical effectiveness of this program requires further investigation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.134-142
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• 2010

Although BinSo-San(BSS), a mixed herbal formula consisted of 11 types of medicinal herbs and have been used as anti-inflammatory agent, In the present study, the acute toxicity (single oral dose toxicity) of lyophilized BSS aqueous extracts was monitored in male and female mice after oral administration according to Korea Food and Drug Administration (KFDA) Guidelines (2005-60, 2005). In order to observe the 50% lethal dose ($LD_{50}$), approximate lethal dosage (ALD), maximum tolerance dosage (MTD) and target organs, test articles were once orally administered to female and male ICR mice at dose levels of 2000, 1000, 500, 250 and 0 (control) mg/kg (body wt.) according to the recommendation of KFDA Guidelines (2005-60, 2005). The mortality and changes on body weight, clinical signs and gross observation were monitored during 14 days after dosing according to KFDA Guidelines (2005-60, 2005) with organ weight and histopathology of 12 types of principle organs. We could not find any mortality, clinical signs and changes in the body weights except for dose-independent increases of body weight and gains restricted in 1000 mg/kg of BSS extracts-dosing female group. Hypertrophic changes of lymphoid organs.thymus, spleen and popliteal lymph nodes were detectedat postmortem observation with BSS extracts dose-dependent increases of lymphoid organ weights, and hyperplasia of lymphoid cells in these all three lymphoid organs at histopathological observations. These changes are considered as results of pharmacological effects of BSS extracts or their components, immunomodulating effects, not toxicological signs. In addition, some sporadic accidental findings such as congestion spots, cyst formation in kidney, atrophy of thymus and spleen with depletion of lymphoid cells, and edematous changes of uterus with desquamation of uterus mucosa as estrus cycles were detected throughout the whole experimental groups including both male and female vehicle controls. The significant (p<0.01) increases of absolute weights of kidney and pancreas detected in BSS extracts 1000 mg/kg-treated female group are considered as secondary changes from increases of body weights. The results obtained in this study suggest that the BSS extract is non-toxic in mice and is therefore likely to be safe for clinical use. The LD50 and ALD of BSS aqueous extracts in both female and male mice were considered as over 2000 mg/kg because no mortalities were detected upto 2000 mg/kg that was the highest dose recommended by KFDA and OECD. In addition, the MTD of BSS extracts was also considered as over 2000 mg/kg because no BSS extracts-treatment related toxicological signs were detected at histopathological observation except for BSS or their component-related pharmacological effects, the immunomodulating effects detected in the present study.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.8
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• pp.304-316
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• 2017

The purpose of this study was to identify the components of the adaptation experiences and factors that help male nurses adapt to clinical nursing settings. The participants were eight male nurses working at general hospitals. Data were collected through in-depth interviews and analyzed using Giorgi's phenomenological analysis methods. The core components of the adaptation experiences of the participants in clinical nursing settings were summarized as 'dedication to work', 'challenges in reality that are different from expectations', 'establishing a professional identity', and 'self-development for the future'. The relationships between these components showed causative, accelerative, and recursive characteristics. The adaptation process was structured in the temporal context. In order for male nurses to adapt well to clinical nursing settings, policy efforts should be made to improve their working conditions and resolve inequalities, such as granting equal opportunities for promotion regardless of sex. In addition, it is essential for male nurses to have sufficient internal control for them to make self-directed efforts to strengthen their willpower and self-development efforts to facilitate their adaptation. This study suggests that developing suitable strategies and policy efforts based on the results is required to assist male nurses in adapting to clinical nursing settings.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.4
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• pp.191-203
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• 2018

Identify the effects of ISO quality management system on the durability of the enterprise by applying it to early startups and small - and medium-sized enterprises. In particular, the quality management system of a technology start-up small and medium sized companies is important in applying the management system to the financial, management and quality control services rather than to research and development. The quality management system is applied to the medical equipment manufacturers, mobile phone brokers, foreign Chinese companies, and components manufacturers for diesel engines.Try it. Check the case where the quality management system has been applied to the company concerned and the nonconformities have been improved. In addition, the success of the project was determined by applying the quality control system to maintain the stability and perpetuation of the company through the case of the failed selection. The company explains that recently, it must appoint internal auditors to carry out continuous improvement activities and that those who want the development and continuity of the company must reflect the quality management system.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1869-1880
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• 2004

In the oriental medicine, a mixture of herbs has been commonly used as important components to control allergic and inflammatory diseases. In the present study, we prepared a mixture of Dictamni Radicis Cortex(Baiksunpee), Houttuyniae Herba(Uhsungcho), and Aurantii Immaturus Fructus(Jisil) to examine its anti-allergic effects in activated mouse splenic cells and found that Mix-1 is involved in regulating levels of B cell activating factors (CD23 and CD11a), IL-1β, IL-6, IL-10, TNF-α, and 1gE as well as HRF expression. It was observed that Mix-1 did not have cytotoxic effects on mLFC. Mix-1 showed inhibition of CD23 and CD11 alpaha expression in mouse B cells, and also decreased the production of IL-6, TNF-α, and 1gE. Both RT-PCR and ELISA analyses indicated that IL-6 and TNF alpha production were regulated at the gene expression level. In contrast, IL-10 mRNA and protein levels were increased in activated B cells by Mix-1 treatment. We also found that Mix-1 inhibited B cell proliferation and inhibited histamine releasing factor(HRF) expression, suggesting its inhibitory effect on histamine secretion. These data indicated that Mix-1 has an anti-allergic effect in activated macrophages and further suggest the possible application of Mix-1 as a therapeutic agent for the treatment of allergy-related diseases.