• Title/Summary/Keyword: Component development

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Separation of Waste TNT and RDX Mixture Using SMB Process (SMB 공정을 이용한 폐기 TNT와 RDX 혼합 용액의 분리)

  • Oh, Donghoon;Kim, Sunhee;Lee, Keundeuk;Ahn, Iksung;Lee, Chang-Ha
    • Clean Technology
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    • v.23 no.2
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    • pp.163-171
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    • 2017
  • Currently, researches on recycling and reuse of waste energetic materials have recently gained a great attention from advanced countries due to ever tightening environmental regulations. In this study, as a part of a recycling technology, the experiments and dynamic simulation of simulated moving bed (SMB) process were performed to efficiently separate TNT and RDX from their mixture, which are main components of ammunition. In order to determine the operation zone of SMB process, the retention times of TNT and RDX were measured using HPLC at different flow rates and the adsorption equilibrium of each component was obtained by using a moment method. According to the adsorption equilibrium and the triangle theory of SMB process, four operation points were determined and separation experiments were carried out by the SMB process using the solvent consisting of acetonitrile and water. Two different mixing ratios (6:4 and 1:1) of acetonitrile and water were chosen for the experiment due to the great impact of mixing ratio of the solvent on separation. The performance of SMB process was evaluated by purity, recovery, productivity and solvent consumption. Pure TNT and RDX were successfully obtained from the SMB process and the dynamic simulation for the SMB process agreed well with the experimental results. Therefore, the dynamic model could be applied for predicting the dynamic behavior of the SMB process and designing a large scale SMB process.

Immunological Characterization of Antigen from Cysticercus and Sparganum, and their Application to the Development of Immunodiagnostic System 2. Immunological Characteriaation of Crude Antigenic Components from Sparganum (Cysticercus와 Sparganum에서 추출한 조항원의 면역학적 특성과 그의 면연진단에 응용 2. Sparganum의 조항원성 분의 면역학적 특성)

  • ;James Yang
    • The Korean Journal of Zoology
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    • v.32 no.4
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    • pp.429-440
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    • 1989
  • Spirometru erinocei의 유충인 sparganum에서 추출한 조항원 단백질을 항원으로 하여 sparganosis, cysticercosis, hydatidosis환자의 IgG 항체와 정상인의 IgG 항체를 혈청반응시켜 ELISA와 EITB에 의해 교차반응을 일으키는 비 특이항원 성분과 종특이항원 성분을 추구하였다. 1. sparganum에서 0.01 M PBS (PH 7.4)로 추출한 조항원 단백질을 SDS-PAGE로 전개하여 290 Kd에서 23 Kd범위의 분자량을 가진 25개의 단백질이 분획되었다. 2. sparganum의 조항원을 항원으로하여 ELISA로 sparganosis, cysticercosis, hydatidosis 환자의 190 항체와의 혈청 반응치는 sparganosis환자에게서는 0.44 $\pm$ 0.07에서 1.90 $\pm$ 0.03으로 negative control normal sera의 0.D (0.15 $\pm$ 0.03)를 기준으로 하였을 때 모두 양성이며 민감도(sensitivity)가 100 %이었으며 cysticercosis, hydatidosis환자혈청에서 양성반응이 나타났으며 교차반응도 있었다. 3. EITB에서는 spargancsis환자의 IgG항체에 의해 16개의 항원성분이 인지되었으며 이 중 6개의 항원성분이 정상인의 혈청에서도 인지되어 교차반응을 일으키는 항원성분이었으며 cysticercosis환자혈청에서 인지된 4개의 항원성분 중 2개의 항원성분이 sparganosis 환자혈청에서 인지된 것과 같았으며 hydatidosis환자의 190항체에 의해 인지된 19개의 항원성분 중 12개의 항원성분이 sparganosis환자혈청에서 인지된 항원 성분과 같았다. 4. 290 Kd, 200 Kd, 28 Kd의 항원성분은 sparganosis환자의 196항체에서만 인지되었고 228 Kd, 152 Kd, 66 Kd항원성분은 hydatidosis환자의 19G항체에서만 인지되었으며 66 Kd항원성분은 sparganosis, cysticercosis, hydatidosis, 정상인의 혈청에서 모두 인지되었다. We studied the serological reaction between the specific and nonspecific antigenic components from metacestode (plerocercoid) of spiromeko erimacei and IgG antibodies in sparganosis, cysticercosis. hydatidosis patients and normal human sera by ELISA and EITB. We prepared the crude extracts of sparganlim from snake, Matrix tigrina laterolis and used as antigenic components. By SDS-PAGE, we detected a total 25 peptide bands (fractions) with 290 Kd to 23 Kd molecular weight, and 8 bands of these detected bands developed strongly by silver stain. In serological test, ELISA, we recognized the cross-reaction of antigenic components reacting with IgG antibodies in heterogenous sera, cysticercosis and hydatidosis patients sera. The crude antigenic components of sparganum showed the high sensitivity in sparganosis, hydatidosis patients sera, but showed lower sensitivity in cysticercosis patients sera than the sparasanosis, hydatidosis patients sera. Sixteen antigenic components of these 25 separated bands were recognized by antibodies In sparsanosis patients sera,8 antigenic components in normal human sera, 4 antigenic components in cysticercosis patients sera and 19 antigenic compoenents in hydatidosis patients sera. The crude antigenic compnenets with 290 Kd, 200 Kd, 125 Kd and 28 Kd molecular weight was only recognized in sparganosis patients sera, but 64 Kd antigenic component was nonspecific antigenic components which were also cross-reacted with sparganosis, hydatidosis, cysticercosis patients sera and normal human sera.

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Formation and Removal of Trihalomethanes based on Characterization of Hydrophobic and Hydrophilic Precursors (전구물질의 소수성 및 친수성 특성에 따른 트리할로메탄의 생성과 제거에 관한 연구)

  • Jeon, Heekyung;Kim, Junsung;Choi, Yoonchan;Choi, Haeyeon;Chung, Yong
    • Journal of Korean Society on Water Environment
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    • v.24 no.1
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    • pp.123-128
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    • 2008
  • The Dissolved Organic Carbon (DOC) existing in a water includes both hydrophobic and hydrophilic substances however, most of the discussion focuses on hydrophobic substances. The hydrophobic fraction was easily removed by absorption or coagulation more than hydrophilic fraction. Therefore, control of the hydrophilic fraction is very important in water treatment process. This study is to determine the variation of DOC, the removal efficiency of DOC, and Trihalomethane formation potential (THMFP) after each stage of water treatment process by fractionating Natural Organic Matters (NOM) into hydrophobic and hydrophilic substance. DOC from raw water was fractionated at acidic pH (pH<2) using XAD 8 resin column, into two fraction : hydrophobic substance (i.e. humic substance) adsorbed on XAD 8 and hydrophilic substance which represent the organics contained in the final effluent. THMFP was carried out according to the following set condition: Cl2/DOC=4 mg/mg, incubation at $25^{\circ}C$ in darkness, pH 7 adjust with HCl or NaOH as necessary, and 72hour-contact time. THMs analyzed in this study were chloroform, bromodichloromethane, dibromochloromethan, and bromoform. Sewage was almost evenly split between the hydrophobic (56%) and hydrophilic fraction (44%). But, Aldrich humic substance (AHS) was found to contain less hydrophilics (14%) than hydrophobics (86%). The formation of THMs may depend on the source which is characterized by the composition of organic matters such as AHS and sewage. The THMFP yield of sewage and AHS were assessed as follows. The value of the THMFP reaction yield, AHS $172.65{\mu}g/mg$, is much higher than that of sewage $41.68{\mu}g/mg$. This illustrates possible significant difference in THMFP according to the component type and the proportion of organic matter existing in water source. Apparently AHS react with chlorine to produce more THMFP than do the smaller molecules found in sewage. Water treatment process may reduce THMFP, nevertheless residual DOC (the more hydrophilic substance) has significant THMFP. Further reduction in organic halide precursors requires application of alternative treatment techniques.

An Overview for Molecular Markers in Plants (식물에서 분자 마커의 동향)

  • Huh, Man Kyu
    • Journal of Life Science
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    • v.25 no.7
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    • pp.839-848
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    • 2015
  • A molecular marker is a molecule contained within a sample taken from an organism or other matter. The development of molecular techniques for genetic analysis has led to a great contribution to our knowledge of plant genetics and our understanding of the structure and behavior of various genomes in plants. Recently, functional molecular markers have been developed to detect the presence of major genes from the analysis of pedigreed data in absence of molecular information. DNA markers have developed into many systems based on different polymorphism-detecting techniques or methods such as RFLP, AFLP, RAPD, SSR, SNP, etc. A new class of very useful DNA markers called genic molecular markers utilizing the ever-increasing archives of gene sequence information being accumulated under the EST sequencing projects on a large number of plant species. Functional markers are derived from polymorphic sequences, and are more likely to be involved in phenotypic trait variation. Based on this conceptual framework, the marker systems discussed below are all (gene)-targeted markers, which have the potential to become functional. These markers being part of the cDNA/EST-sequences, are expected to represent the functional component of the genome i.e., gene(s), in contrast to all other random DNA based markers that are developed/generated from the anonymous genomic DNA sequences/domains irrespective of their genic content/information. Especially I sited Poczai et al’ reviews, advances in plant gene-targeted and functional markers. Their reviews may be some useful information to study molecular markers in plants.

Neuropsychological Approaches to Mathematical Learning Disabilities and Research on the Development of Diagnostic Test (신경심리학적 이론에 근거한 수학학습장애의 유형분류 및 심층진단검사의 개발을 위한 기초연구)

  • Kim, Yon-Mi
    • Education of Primary School Mathematics
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    • v.14 no.3
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    • pp.237-259
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    • 2011
  • Mathematics learning disabilities is a specific learning disorder affecting the normal acquisition of arithmetic and spatial skills. Reported prevalence rates range from 5 to 10 percent and show high rates of comorbid disabilities, such as dyslexia and ADHD. In this study, the characteristics and the causes of this disorder has been examined. The core cause of mathematics learning disabilities is not clear yet: it can come from general cognitive problems, or disorder of innate intuitive number module could be the cause. Recently, researchers try to subdivide mathematics learning disabilities as (1) semantic/memory type, (2) procedural/skill type, (3) visuospatial type, and (4) reasoning type. Each subtype is related to specific brain areas subserving mathematical cognition. Based on these findings, the author has performed a basic research to develop grade specific diagnostic tests: number processing test and math word problems for lower grades and comprehensive math knowledge tests for the upper grades. The results should help teachers to find out prior knowledge, specific weaknesses of students, and plan personalized intervention program. The author suggest diagnostic tests are organized into 6 components. They are number sense, conceptual knowledge, arithmetic facts retrieval, procedural skills, mathematical reasoning/word problem solving, and visuospatial perception tests. This grouping will also help the examiner to figure out the processing time for each component.

Design and Implementation of an Analysis System for Diseases and Protein Based on Components (컴포넌트 기반의 질병 및 단백질 분석 시스템의 설계 및 구현)

  • Park, Jun-Ho;Yeo, Myung-Ho;Lee, Ji-Hee;He, Li;Kang, Gwang-Goo;Kwon, Hyun-Ho;Lee, Jin-Ju;Lee, Hyo-Joon;Lim, Jong-Tae;Jang, Yong-Jin;WeiWei, Bao;Kim, Mi-Kyoung;Ryu, Jae-Woon;Kang, Tae-Ho;Kim, Hak-Yong;Yoo, Jae-Soo
    • The Journal of the Korea Contents Association
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    • v.10 no.12
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    • pp.59-69
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    • 2010
  • The research on protein for the diseases analysis and the new medicines development is one of the most important themes in biotechnology. Since the analysis on diseases and protein needs to handle a large scale of data, we don't use the way to approach it by the experiments anymore. In recent, we have accelerated the research on diseases and protein analysis by sharing and connecting the various experimental data by combining the biotechnology with the IT technology. However, many biotechnology researchers have difficulty in handling the protein analysis tools based on the IT knowledge. In order to solve such problems, data analysis tools through the cooperation between IT researchers and biologists have been developed. However, the existing data analysis tools still have the problems that it is very hard for biologists to extend their functions and to use them. In this paper, we design and implement an effective analysis system for diseases and protein based on components that alleviates the problems of the existing data analysis systems.

Future Inundation Characteristics Analysis for the Cheongmi Stream Watershed Considering Non-stationarity of Precipitation (강우의 비정상성을 고려한 청미천 유역의 미래 침수특성 분석)

  • Ryu, Jeong Hoon;Kang, Moon Seong;Jun, Sang Min;Park, Jihoon;Lee, Kyeong-Do
    • Journal of The Korean Society of Agricultural Engineers
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    • v.59 no.1
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    • pp.81-96
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    • 2017
  • Along with climate change, it is reported that the scale and the frequency of extreme climate events (e.g. heavy rain, typhoon, etc.) show unstable tendency of increase. In case of Korea, also, the frequency of heavy rainfall shows increasing tendency, thus causing natural disaster damage in downtown and agricultural areas by rainfall that exceeds the design criteria of hydraulic structures. In order to minimize natural disaster damage, it is necessary to analyze how extreme precipitation event changes under climate change. Therefore a new design criteria based on non-stationarity frequency analysis is needed to consider a tendency of future extreme precipitation event and to prepare countermeasures to climate change. And a quantitative and objective characteristic analysis could be a key to preparing countermeasures to climate change impact. In this study, non-stationarity frequency analysis was performed and inundation risk indices developed by 4 inundation characteristics (e.g. inundation area, inundation depth, inundation duration, and inundation radius) were assessed. The study results showed that future probable rainfall could exceed the existing design criteria of hydraulic structures (rivers of state: 100yr-200yr, river banks: 50yr-100yr) reaching over 500yr frequency probable rainfall of the past. Inundation characteristics showed higher value in the future compared to the past, especially in sections with tributary stream inflow. Also, the inundation risk indices were estimated as 0.14 for the past period of 1973-2015, and 0.25, 0.29, 1.27 for the future period of 2016-2040, 2041-2070, 2071-2100, respectively. The study findings are expected to be used as a basis to analyze future inundation damage and to establish management solutions for rivers with inundation risks.

A Study on the Development of Forest Fire Occurrence Probability Model using Canadian Forest Fire Weather Index -Occurrence of Forest Fire in Kangwon Province- (캐나다 산불 기상지수를 이용한 산불발생확률모형 개발 -강원도 지역 산불발생을 중심으로-)

  • Park, Houng-Sek;Lee, Si-Young;Chae, Hee-Mun;Lee, Woo-Kyun
    • Journal of the Korean Society of Hazard Mitigation
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    • v.9 no.3
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    • pp.95-100
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    • 2009
  • Fine fuel moisture code (FFMC), a main component of forest fire weather index(FWI) in the Canadian forest fire danger rating system(CFFDRS), indicated a probability of ignition through expecting a dryness of fine fuels. According to this code, a rising of temperature and wind velocity, a decreasing of precipitation and decline of humidity in a weather condition showed a rising of a danger rate for the forest fire. In this study, we analyzed a weather condition during 5 years in Kangwon province, calculated a FFMC and examined an application of FFMC. Very low humidity and little precipitation was a characteristic during spring and fall fire season in Kangwon province. 75% of forest fires during 5 years occurred in this season and especially 90% of forest fire during fire season occurred in spring. For developing of the prediction model for a forest fire occurrence probability, we used a logistic regression function with forest fire occurrence data and classified mean FFMC during 10 days. Accuracy of a developed model was 63.6%. To improve this model, we need to deal with more meteorological data during overall seasons and to associate a meteorological condition with a forest fire occurrence with more research results.

Software Development for the Visualization of the Orientation of Brain Fiber Tracts in Diffusion Tensor Imaging Using a 24 bit Color Coding

  • Jung-Su Oh;In Chan Song;Ik-Hwan Cho;Jong-Hyo Kim;Kee Hyun Chang;Kwang-Suk Park
    • Journal of Biomedical Engineering Research
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    • v.25 no.1
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    • pp.43-47
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    • 2004
  • Interests in human brain functionality and its connectivity have much frown up. DTI (Diffusion tensor imaging) has been known as a non-invasive MR) technique capable of providing information on water diffusion in tissues and the organization of white matter tract. Thus. It can provide us the information on the direction of brain fiber tract and the connectivity among many important cortical regions which can not be examined by other anatomical or functional MRI techniques. In this study. was used the 24 bit color coding scheme on the IDL platform in the windows environment to visualize the orientation of major fiber tracts of brain such as main association, projection, commissural fibers and corticospinal tracts. We additionally implemented a color coding scheme for each directional component and FA (fractional anisotropy), and used various color tables for them to be visualized more definitely. Consequently we implemented a fancy and basic technique to visualize the directional information of fiber tracts efficiently and we confirmed the feasibility of the 24 bit color coding scheme in DTI by visualizing main fiber tracts.

A Preliminary Development of Real-Time Hardware-in-the-Loop Simulation Testbed for the Satellite Formation Flying Navigation and Orbit Control (편대비행위성의 항법 및 궤도제어를 위한 실시간 Hardware-In-the-Loop 시뮬레이션 테스트베드 초기 설계)

  • Park, Jae-Ik;Park, Han-Earl;Shim, Sun-Hwa;Park, Sang-Young;Choi, Kyu-Hong
    • Journal of Astronomy and Space Sciences
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    • v.26 no.1
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    • pp.99-110
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    • 2009
  • The main purpose of the current research is to developments a real-time Hardware In-the-Loop (HIL) simulation testbed for the satellite formation flying navigation and orbit control. The HIL simulation testbed is integrated for demonstrations and evaluations of navigation and orbit control algorithms. The HIL simulation testbed is composed of Environment computer, GPS simulator, Flight computer and Visualization computer system. GPS measurements are generated by a SPIRENT GSS6560 multi-channel RF simulator to produce pseudorange, carrier phase measurements. The measurement date are transferred to Satrec Intiative space borne GPS receiver and exchanged by the flight computer system and subsequently processed in a navigation filter to generate relative or absolute state estimates. These results are fed into control algorithm to generate orbit controls required to maintain the formation. These maneuvers are informed to environment computer system to build a close simulation loop. In this paper, the overall design of the HIL simulation testbed for the satellite formation flying navigation and control is presented. Each component of the testbed is then described. Finally, a LEO formation navigation and control simulation is demonstrated by using virtual scenario.