• Title/Summary/Keyword: Component development

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The Effects of Cynanchi wilfordii Radix Ethanol Extracts upon Irradiated Rat's Blood and Organ (백하수오 에탄올추출물이 방사선조사에 따른 흰쥐의 혈구 및 장기에 미치는 영향)

  • Kim, Jang-Oh;Choi, Jun-Hyeok;Shin, Ji-Hye;Jung, Do-Young;Min, Byung-In
    • Journal of radiological science and technology
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    • v.39 no.3
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    • pp.451-459
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    • 2016
  • The development of radioprotector is being actively conducted in order to reduce the damage from over radiation exposure at radiation accident or radiation therapy. So this study was confirmed for radiation protective effects using the Cynanchi wilfordii Radix that has been known to be effective for antioxidant activity, anti-cancer, immune enhancing effects. The method of this study was administered orally Cynanchi wilfordii Radix ethanol extracts to Sprague Dawley Rat(SD Rat) for 14 days once a day, while measuring changed blood cell, spleen index, liver and uterus tissue along the change in time of 1, 4, 7 and 21 days after X-ray beam of 7 Gy irradiation. As the result of the experiment, the experimental group's rats which are administered with Cynanchi Wilfordii Radix ethanol extracts showed a rapid recovery in white blood cell count(p < 0.05) and spleen index(p < 0.05). In addition, condensation of nuclei, cytoplasmic swelling, and inflammatory cell infiltration in experimental group's liver cell was decreased more than in irradiation group's component. Further, experimental group's Uterine gland decreased the apoptosis more than irradiation group's components did. It is expected that Cynanchi Wilfordii Radix extracts will be useful as a new radioprotector. With above in mind, this paper may provide appropriate implications with the field of emergency management such as radiation accident.

Development of Gait Event Detection Algorithm using an Accelerometer (가속도계를 이용한 보행 시점 검출 알고리즘 개발)

  • Choi, Jin-Seung;Kang, Dong-Won;Mun, Kyung-Ryoul;Bang, Yun-Hwan;Tack, Gye-Rae
    • Korean Journal of Applied Biomechanics
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    • v.19 no.1
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    • pp.159-166
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    • 2009
  • The purpose of this study was to develop and automatic gait event detection algorithm using single accelerometer which is attached at the top of the shoe. The sinal vector magnitude and anterior-posterior(x-axis) directional component of accelerometer were used to detect heel strike(HS) and toe off(TO), respectively. To evaluate proposed algorithm, gait event timing was compared with that by force plate and kinematic data. In experiment, 7 subjects performed 10 trials level walking with 3 different walking conditions such as fast, preferred & slow walking. An accelerometer, force plate and 3D motion capture system were used during experiment. Gait event by force plate was used as reference timing. Results showed that gait event by accelerometer is similar to that by force plate. The distribution of differences were spread about $22.33{\pm}17.45m$ for HS and $26.82{\pm}14.78m$ for To and most error was existed consistently prior to 20ms. The difference between gait event by kinematic data and developed algorithm was small. Thus it can be concluded that developed algorithm can be used during outdoor walking experiment. Further study is necessary to extract gait spatial variables by removing gravity factor.

Estimation of Korea Transportation Service Index and Business Cycle Analysis (국내 교통산업 서비스 지수의 산정 및 경기순환분석)

  • Han, Sang-Yong;Jeong, Gyeong-Ok;Jeong, Gyeong-Min
    • Journal of Korean Society of Transportation
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    • v.24 no.2 s.88
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    • pp.53-63
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    • 2006
  • The objective of this study is to estimate Korean transportation service index (KTSI), and to explore possible uses of the KTSI. The KTSI was monthly index to represent the level of passenger and freight services by road, railroad, air and maritime modes, which was developed from eight series. Four of these series measure the level of passenger services (passenger-kilometers) by road, railroad. air and maritime modes : monthly data from January 1995 to December 2004. Similarly. the remaining four series measure the level or freight activity (tonnage) by four modes during the same period. Given the weights of modal revenues, component series were aggregated into two indexes (passenger index and freight index) and a composite index using Chained Fisher Ideal index. which was a geometric mean of the Laspeyres index and the Passche index. The Fisher Ideal index is one of the 'superlative' indexes, which diminish 'substitution bias' as current-weighted indexes. As a result, the freight index and the composite index explain economic conditions better than the passenger index. Based on the composite index. the newly estimated KTSI shows an average lag time of one and a half years at peaks and three months at troughs in comparison with domestic business cycles. Nonetheless. the following efforts are needed for more credible and useful estimates; establishment of data collection scheme in time. credibility uplift of used data, development of various indexation methods.

Development and Evaluation of Runoff-Sediment Evaluation System and BMPs Evaluation Modules for Agricultural Fields using Hourly Rainfall (시강우량을 이용한 필지별 유출-유사 평가 시스템 및 BMPs 평가 모듈 개발 및 적용성 평가)

  • Kum, Donghyuk;Ryu, Jichul;Choi, Jaewan;Shin, Min Hwan;Shin, Dong Suk;Cheon, Se Uk;Choi, Joong-Dae;Lim, Kyoung Jae
    • Journal of Korean Society on Water Environment
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    • v.28 no.3
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    • pp.375-383
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    • 2012
  • Soil erosion has been emphasized as serious environmental problem affecting water quality in the receiving waterbodies. Recently, Best Management Practices (BMPs) have been applied at a field to reduce soil erosion and its effectiveness in soil erosion reduction has been monitored with various methods. Although monitoring at fields/watershed outlets would be accurate way for these ends, it is not possible at some fields/watersheds due to various limitations in direct monitoring. Thus modeling has been suggested as an alternative way to evaluate effects of the BMPs. Most models, which have been used in evaluating hydrology and water quality at a watershed, could not reflect rainfall intensity in runoff generation and soil erosion processes. In addition, source codes of these models are not always public for modification/enhancement. Thus, runoff-sediment evaluation system using hourly rainfall data and vegetated filter strip (VFS) evaluation module at field level were developed using open source MapWindow GIS component in this study. This evaluation system was applied to Bangdongri, Chuncheonsi to evaluate its prediction ability and VFS module in this study. The NSE and $R^2$ values for runoff estimation were 0.86 and 0.91, respectively, and measured and simulated sediment yield were 15.2 kg and 16.5 kg indicating this system, developed in this study, can be used to simulate runoff and sediment yield with acceptable accuracies. Nine VFS scenarios were evaluated for effectiveness of soil erosion reduction. Reduction efficiency of the VFS was high when sediment inflow was small. As shown in this study, this evaluation system can be used for evaluation BMPs with local rainfall intensity and variations considered with ease-of-use GIS interface.

Artificial Trachea Covered by Ipithelium (상피세포 피복 인공기관의 개발)

  • 김광택;이윤신
    • Journal of Chest Surgery
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    • v.30 no.8
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    • pp.739-746
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    • 1997
  • A variety of experiments concerning the development of ideal prosthetic grafts for correcting circumferential tracheal defects have been performed. The requirements for an ideal tracheal prosthesis are impermeability to air, consistency to prevent collapse, and acceptance by the host tissue causing a minimum inflammatory reaction, allowing fibroblastic infiltration and epithelialization. The synthetic material, polyurethane(PU), is known as a biocompatible polymer with an inert component. In this study, the tracheal prosthesis was made from microporous PU(30 micrometer in diameter) coated with gelatin and reinforced with isoplastic rings. This procedure provides the prosthesis with a compression strength. The out side diame er of the prosthesis was 20 mm with a length of 30 mm. The gelatin used in the study was obtained from pig skin and immobilized and cross-linked by irradiation(60 Co gamma ray) to promote host tissue incorporation and render the prosthesis epithelization after implantation. Animal experiments using 10 mongrel dogs were performed to compare three kinds of prosthesis; gelatin coated polyurethane graft, uncoated polyurethane graft, and prosthesisf pericadium complex graft. After 6 weeks of implantation, the epithelialization of implants was seen on the gelatin-coated and prosthesisfpericadium complex grafts. Implanted prosthesis were complicated by airway obstruction due to anastomosis granuloma. Early tracheal stenosis was found in the uncoated graft group. Two kind of anastomosis techniques were tested on the gelatin-coated prosthesis. Everted anastomosis resulted severe granuloma than the inverted anastomosis. In the prosthesislpericadium complex graft, bacteria and inflammation at a anastomotic site was found. Based on these results, gelatin coated porous polyurethane trachea prosthesis is biocompatible and may be useful in clinical application with further investigation.

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A Study on the Torsional Vibration Characteristics of Super Large Two Stroke Low Speed Diesel Engines with Tuning Damper (튜닝댐퍼를 갖는 초대형 저속 2행정 디젤엔진의 비틀림진동 특성에 관한 연구)

  • Lee, Don-Chool;Barro, Ronald D.
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.19 no.1
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    • pp.64-75
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    • 2009
  • The shipbuilder's requirement for a higher power output rating has led to the development of a super large two stroke low speed diesel engines. Usually a large-sized bore engine ranging from $8{\sim}14$ cylinders, this engine group is capable of delivering power output of more than 100,000 bhp at maximum continuous rating(mcr). Other positive aspects of this engine type include higher thermal efficiency, reliability, durability and mobility. This plays a vital role in meeting the propulsion requirement of vessels, specifically for large container ships, of which speed is a primary concern to become more competitive. Consequently, this also resulted in the modification of engine parameters and new component designs to meet the consequential higher mean effective pressure and higher maximum combustion pressure. Even though the fundamental excitation mechanisms unchanged, torsional vibration stresses in the propulsion shafting are subsequently perceived to be higher. As such, one important viewpoint in the initial engine design is the resulting vibration characteristic expected to prevail on the propulsion shafting system(PSS). This paper investigated the torsional vibration characteristics of these super large engines. For the two node torsional vibration with a nodal point on the crankshaft, a tuning damper is necessary to reduce the torsional stresses on the crankshaft. Hence, the tuning torsional vibration damper design and compatibility to the shafting system was similarly reviewed and analyzed.

Development of HyGIS-RAS and HMS Model (HyGIS-RAS모형 및 HyGIS-HMS모형의 개발)

  • Han, Kun-Yeun;Kim, Byung-Hyun;Son, Ah-Long;Kim, Tae-Hyung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.1342-1347
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    • 2007
  • 최근 수자원 분야에서 GIS의 활용은 유역의 수리, 수문분석을 위한 모형의 입력자료 생성 및 모의 결과를 가시화, 이에 따른 유역관리 시스템의 구축 등 폭넓게 활용되고 있다. 또한 국가지리정보시스템에 조사를 통해서 수치지형도 및 주제도를 구축, 구축된 자료의 표준화를 실시하고 있는 실정이다. 그러나 수자원 분야에서 GIS를 활용하기 위한 기술은 주로 선진국을 중심으로 발전하여 왔기 때문에 우리의 실정에 맞지 않아 활용측면에 있어 신뢰할 만한 결과를 얻지 못하고 있는 실정이다. 따라서 국내 상황을 고려하면서 수자원이라는 전문분야 적용에 적합한 GIS(HyGIS)를 개발하고 여기에 수리, 수문분석모형을 연계하여 국내 실무분야에 적용함에 있어 편의성과 실용성을 구비한 모형개발이 이루어져야 한다. 따라서 본 연구에서는 국내 소프트웨어 GeoMania(HyGIS)에 의한 GIS 정보처리의 자동화를 기반으로 하여 실무에서 활용도가 높은 수문모형인 HEC-HMS 및 HEC-1과 수리모형인 HEC-RAS를 연계 및 통합하기 위해서 HyGIS에서 DLL형태로 제공되도록 하였다. HyGIS에서는 수문학적 DEM 분석 및 공간정보 생성, 선형참조가 가능한 하천 네트워크 생성, 유역 시설물 관리 등의 기능을 제공하며 COM(Component Object Model)을 기반으로 개발된 시스템으로 다른 소스로부터 개발된 컴포넌트를 연계하여 시스템의 기능 확장을 손쉽게 수행할 수 있도록 하였을 뿐만 아니라 공간 DB는 GeoMania의 고유 DB인 GSS를 이용한다. HyGIS-HMS는 HyGIS를 통한 국내 유역의 지리정보를 활용하여 HEC-HMS 뿐만 아니라 HEC-1을 추가하여 사용자의 기호와 편의에 따라 모형을 선택할 수 있도록 하였으며 HEC-1의 결과를 가시화하기 위해서 챠트 기능을 추가하였으며 매개변수를 자동으로 산정할 수 있도록 시스템을 구축하였다. HyGIS-RAS는 국내 하천유역에 대해서 기구축 되어있는 하천관리지리정보시스템(RIMGIS)자료를 직접 활용하도록 구성되어있고 자료를 활용하여 제내지와 제외지를 통합하여 TIN분석을 실시하여 범람 홍수해석에 활용할 수 있도록 하였다. 하천수리해석의 기능을 보강하기 위해 역산조도계수 산정모형, 상류-사류 천이류 구간에 대한 부등류 해석모형, 범람 홍수류에 대한 홍수위 산정모형, 하천수리계산시의 불확실도 해석모형 등의 새로운 기능을 추가하여 제시하였다. 모든 입출력자료는 프로젝트 단위별로 운영되어 data의 관리가 손쉽도록 하였으며 결과를 DB에 저장하여 다른 모형에서도 적용할 수 있도록 하였다. 그리고 HyGIS-HMS 및 HyGIS-RAS 모형에서 강우-유출-하도 수리해석-범람해석 등이 일괄되게 하나의 시스템 내에서 구현될 수 있도록 하였다. 따라서 HyGIS와 통합된 수리, 수문모형은 국내 하천 및 유역에 적합한 시스템으로서 향후 HydroInformatics 구현을 염두에 둔 특화된 국내 수자원 분야 소프트웨어의 개발에 기본 토대를 제공할 것으로 판단된다.

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Changes of chemical constituents in extract of Lycii fructus by various heat treatment (가열처리(加熱處理)에 따른 구기자(枸杞子) 추출물(抽出物)의 성분변화(成分變化))

  • Yi, Sang-Duck;Lee, Mi-Hyun;Son, Hyun-Ju;Bock, Jin-Young;Sung, Chang-Keun;Kim, Chan-Jo;Oh, Man-Jin
    • Applied Biological Chemistry
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    • v.39 no.4
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    • pp.268-273
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    • 1996
  • Fundamental data for new type of product development from Lycii fructus was experimentally determined. The chemical composition, and Hunter value changes, optimum extraction, volatile components of extract under different extraction conditions and heat treatment were mainly studied. Results are summarized as follows. The proximate compositions of dried Lycii fructus were water 21.8%, total sugar 27.6%, reducing sugar 15.2%, crude protein 14.29%, crude fat 5.65%, crude fiber 7.48%, and ash 7.98% in percent stale, respectively. Extracted yield on the basic of solid extract was getting increased when more solvent was used for extraction. The most recommendable extraction was 1 to 10 part of sample to solvent ratio. When water was employed as extraction solvent, the highest amount of solid extract was obtained. Extract of Lycii fructus in terms of yields and color was most acceptable when raw sample was treated 8 minute roasting at $180^{\circ}C$ and 60 minute heating at $120^{\circ}C$, respectively. Major volatile components of fresh Lycii fructus were to hexadecanoic acid, methyl linoleate, benzyl alcohol, dimetane benzene by GC/MS. By the roasting of raw sample, the compounds of 2-methyl-2buthenal, 1,4-dimethyl benzene, and benzyl alcohol were reduced. Wheras, methyl thiopropanol, benzene acetaldehyde and ethyl linoleate were slightly increased.

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Variation in Antioxidant Components of Black Soybean as Affected by Variety and Cultivation Region (재배지역에 따른 검정콩 항산화 성분의 함량변이)

  • Yi, Eun-Seob;Yi, Yong-Seon;Yoon, Seong-Tak;Lee, Hyuk-Geun
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.54 no.1
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    • pp.80-87
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    • 2009
  • Aiming at development of region specialized crop, this study was conducted to clarify variety and cultivation region dependent on antioxidative compounds in black soybean seeds. For this purpose two black soybean varieties (Ilpumgeomjeongkong and Cheongjakong) were cultivated in 3 different regions (Hwaseong in Gyeonggido, Naju in Jeollanamdo and Jinju in Gyeongsangnamdo) in 2004 and 2005, and harvested seeds were used for isoflavone, anthocyanin and tocopherol contents along with electron donating ability-based antioxidative activities measurements. 100 grain weight between two varieties were not significantly different, but Hwaseong district showed higher 100 grain weight compared to Jinju and Naju. Ilpumgeomjeongkong was higher total isoflavone content ($1,064.9{\mu}g/g$) compared to Cheongjakong ($801.3{\mu}g/g$) in 2004, whereas Cheongjakong showed higher in 2005 compared to Ilpumgeomjeongkong. The highest isoflavone content was obtained in Hwaseong district in 2004, whereas it is the reverse in 2005 that Jinju district showed the highest isoflavone content. In total anthocyanin content, Ilpumgeomjeongkong (7.22 mg/g) was higher than that of Cheongjakong (6.83 mg/g), and Jinju district showed the highest total anthocyanin content (9.16 mg/g) compared to Naju and Hwaseong cultivating districts in their three cultivating districts. Total tocopherol content showed no significant difference between two varieties, but Hwaseong ($217.2{\mu}g/g$) and Jinju ($216.3{\mu}g/g$) districts showed higher content compared to Naju ($189.7{\mu}g/g$) among three cultivating districts. In tocopherol content ratio, $\gamma$-tocopherol was the highest from 56.2% to 59.9%. In electron donating ability (EDA) between two cultivars, Ilpumgeomjeongkong was significantly higher than Cheongjakong, and Naju was the highest of 55.6% among three cultivating districts.

A Scenario-based Goal-oriented Approach for Use Case Modeling (유즈케이스 모델링을 위한 시나리오 근간의 목표(Goal)지향 분석 방안)

  • Lee, Jae-Ho;Kim, Jae-Seon;Park, Soo-Yong
    • Journal of KIISE:Software and Applications
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    • v.29 no.4
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    • pp.211-224
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    • 2002
  • As system become larger and more complex, it is important to correctly analyze and specify user's requirements. Use case modeling is widely used in Object-Oriented Analysis and Design(OOAD) and Component-Based Development(CBD). It is useful to mitigate the complexity of the requirements analysis. However, use cases are difficult to be structured, to explicitly represent non-functional requirements, and to analyze what is affected by changes of use cases. To alleviate these problems, we propose scenario-based goal-oriented approach for use case modeling. The approach is to apply goal-oriented analysis method to use case model. Since goal-oriented analysis method is not systematic and heuristics is considerably involved, we adopted scenarios as the basis for the goal extraction. The proposed method is applied to City Bus Information Subsystem(CBIS) in Intelligent Transport Systems(ITS) domain. The proposed approach helps software engineer to analyze what is affected by use case's changes and represent non-functional requirements.