• Fashion & Textile Research Journal
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• v.16 no.2
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• pp.255-265
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• 2014

This study developed and proposed a pattern that can fit the body and compensate for the defects of the body type by applying shoulder princess line to the torso pattern and including formative characteristics of each object on the study of body shape's change in 40-59 year old middle aged women. The results of this study are as follows; First, according to the analysis of 'Size Korea 2010' such as average, standard deviation, minimum value, and maximum value of 48 items, women showed increase in most of the items except height as they became aged. Second, factor analysis was made to understand the shape component factors of middle aged women and to use them for the body type classification. Third, cluster analysis was made according to the shape of front and sides which should be considered in pattern production based on the factor analysis results, and the body type with the measurement values most similar to the average of direct measurement of 'Size Korea 2010' was set as standard. Fourth, in designing torso patterns through the $1^{st}$ and the $2^{nd}$ wearing experiments according to the body type, body shapes such as Chest Circumference, Waist Circumference, Hip Circumference, and Waist Back Length were considered in pattern design, goodness-of-fit was enhanced with difference in margin according to body type and different margins in front and back, and fitting satisfaction was improved by applying princess line.

• Journal of Advanced Marine Engineering and Technology
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• v.37 no.8
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• pp.946-952
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• 2013

Large scale fire tests were conducted to develop water mist nozzles as a component of fixed water- based fire fighting systems for Ro-Ro spaces and special category spaces. Fire scenarios for this system consist of two cases which are for cargo fire in a simulated truck and for passenger vehicle fire, and each case has 3 different tests according to the position between fixed water mist nozzles and fire source. Every experiment proceeded for 30 minutes and acceptance criteria were based on gas temperature, fuel package's damage and ignition of targets. This study primarily dealt with the experimental results of cargo fire and focused on fire suppression capability in accordance with discharge pressure, flow rate and flow characteristics like swirl and penetration of the developed water mist nozzles. It appeared that low pressure water mist nozzles with about 40 L/min were able to control fire occurred in Ro-Ro spaces.

• Progress in Medical Physics
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• v.27 no.4
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• pp.232-235
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• 2016

The purpose of this study is to develop the treatment planning system (TPS) based on Monte-Carlo simulation for BNCT. In this paper, we will propose a method for dose estimation by Monte-Carlo simulation using the CT image, and will evaluate the accuracy of dose estimation of this TPS. The complicated geometry like a human body allows defining using the lattice function in MCNPX. The results of simulation such as flux or energy deposition averaged over a cell, can be obtained using the features of the tally provided by MCNPX. To assess the dose distribution and therapeutic effect, dose distribution was displayed on the CT image, and dose volume histogram (DVH) was employed in our developed system. The therapeutic effect can be efficiently evaluated by these evaluation tool. Our developed TPS could be effectively performed creating the voxel model from CT image, the estimation of each dose component, and evaluation of the BNCT plan.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.12
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• pp.1379-1385
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• 2014

Even the rough prediction of the product test time before the lifetime test of mechanical component begins would be of use in estimating cost and deciding how to keep up with the test. The reliability predictions of mechanical components are difficult because failure or degradation mechanisms are complicated, and few plausible databases are available for lifetime prediction. Therefore, this study conducted lifetime predictions of elastomeric U seals that were respectively installed in a hydraulic actuator and a pneumatic actuator using lifetime models and a field database based on failure physics and an actual test database obtained from the NSWC handbook. To validate the results, the predicted failure rates were compared with the actual lifetime test results acquired in the lab durability tests. Finally, this study discussed an engineering procedure to determine the coefficients in the failure rate models and analyzed the sensitivity of each influential parameter on the seal lifetime.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.12
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• pp.1359-1365
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• 2014

In this study, 1-way fluid structure interaction analysis(FSI) for the shutter, component of side jet thruster was performed to evaluate the safety. Driving torque to open nozzle, thermal and high pressure load of hot gas was applied to shutter. Thus, the shutter must be designed to endure this load during combustion. We carried out computational fluid dynamics analysis to obtain the pressure, temperature, and heat transfer coefficient of hot gas of side jet thruster. We then used the data as the load condition for a thermal structural analysis using a mapping method. The locations with the maximum stress and temperature distributions were found. We compared the maximum stress with the tensile stress of shutter material according to temperature to evaluate the safety. We also analyzed the radial deformation of the shutter to set the proper interface gap with the side jet thruster parts.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.6
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• pp.731-738
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• 2013

This paper describes a fault-tolerant driving control strategy for an independent steer-by-wire system in sixwheel-drive/six-wheel-steering vehicles. An algorithm has been designed to realize vehicle maneuverability that is as close as possible to that of non-faulty vehicles by inducing high slip ratio of the wheel through a faulty steer-by-wire system in order to reduce the lateral tire force, which is resistant to the yaw motion. Considering the transition of the longitudinal tire force of a wheel with a faulty steer-by-wire component, the longitudinal tire forces are optimally distributed to the other wheels. Fault-tolerant driving performance has been investigated via computer simulations. Simulation studies show that the proposed algorithm can significantly improve the maneuverability of a vehicle with a faulty steer-by-wire system as compared to the optimal traction distribution method.

• Journal of Korean Tunnelling and Underground Space Association
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• v.5 no.1
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• pp.23-31
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• 2003

Since the mid of 1990, permanent shotcrete tunnel linings such as Single-shell and NMT have been constructed in many countries for reducing the construction time and lowing construction costs instead of conventional in-situ concrete linings. Among essential technologies for successful application of permanent shotcrete linings, high performance shotcrete having high strength, high durability and better pumpability has to be developed in advance as an integral component. This paper presents the idea and first experimental attempts to increase early strength and bond strength of wet-mixed Steel Fiber Reinforced Shotcrete (SFRS) in spring water condition. In order to increase early behavior of SFRS, a new approach using high-early strength cement with alkali-free liquid accelerator has been investigated. From the test results, wet-mix SFRS with high-early strength cement and alkali-free accelerator exhibited excellent early compressive strength improvement compared to the ordinary portland cement and good bond strength even under spring water condition.

• Korean Medical Education Review
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• v.22 no.3
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• pp.146-152
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• 2020

Hospice and palliative care (HPC) education is an essential component of undergraduate medical education. Since February 4th, 2018, withholding and withdrawing life-sustaining treatment at the end of life (EOL) has been permitted in Korea as put forth by law, the "Act on Hospice and Palliative Care and Decisions on Life-Sustaining Treatment for Patients at the End of Life." Therefore, Korean medical schools have faced a challenge in providing comprehensive HPC education in order to better prepare medical students to be competent physicians in fulfilling their role in caring for patients at the EOL. There have been considerable variations in the evolution and organization of HPC education across Korean medical schools for the past 20 years. In 2016, all medical schools taught HPC curriculum as a separate course or integrated courses, with the most frequently taught topics including: delivering bad news, pain management, and the concept of palliative medicine. However, the content, time allocation, learning format, and clinical skills practice training of HPC education have been insufficient, inconsistent, and diverse. For this reason, we propose a HPC curriculum containing seven domains with 60 learning objectives in a course duration of over 20 hours based on the Palliative Education Assessment Tool (PEAT) as standard HPC curriculum. Furthermore, we recommend development of a national curriculum for HPC/EOL care education to be organized by the HPC board and managed under the accreditation criteria of the Korea Institute of Medical Education and Evaluation.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2015-2020
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• 2012

Oleanolic acid (OA) is a naturally occurring triterpenoid in food materials and is a component of the leaves and roots of Olea europaea, Viscum album L., Aralia chinensis L. and more than 120 other plant species. There are several reports validating its antitumor activity against different cancer cells apart from its hepatoprotective activity. However, antitumor activity against skin cancer has not beed studied well thus far. Hence the present study of effects of OA against HaCaT (immortalized keratinocyte) cells - a cell-based epithelial model system for toxicity/ethnopharmacology-based studies - was conducted. Radical scavenging activity ($DPPH{\cdot}$) and FRAP were determined spectrophotometrically. Proliferation was assessed by XTT assay at 24, 48 and 72 hrs with exposure to various concentrations (12.5-200 ${\mu}M$) of OA. Apoptotic induction potential of OA was demonstrated using a cellular DNA fragmentation ELISA method. Morphological studies were also carried out to elucidate its antitumor potential. The results revealed that OA induces apoptosis by altering cellular morphology as well as DNA integrity in HaCaT cells in a dose-dependent manner, with comparatively low cytotoxicity. The moderate toxicity observed in HaCaT cells, with induction of apoptosis, possibly suggests greater involvement of programmed-cell death-mediated mechanisms. We conclude that OA has relatively low toxicity and has the potential to induce apoptosis in HaCaT cells and hence provides a substantial and sound scientific basis for further validation studies.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3123-3129
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• 2013

Background: The search for naturally occurring agents in routinely consumed foods that may inhibit cancer development is of high priority. [6]-Paradol is a pungent phenolic bioactive component from ginger with welldocumented health promoting antioxidant, antimutagenic, antigenotoxic and anti-inflammatory properties. However, anticarcinogenic effects have yet to be fully explored. The objectives of the present study were therefore to assess protective effects against 7,12-dimethylbenz(a)anthracene (DMBA) induced buccal pouch carcinogenesis in male golden Syrian hamsters. Methods: Oral squamous cell carcinomas developed in the left buccal pouch of hamsters on painting with 0.5% of DMBA, three times in a week. To assess the apoptotic associated gene expressing potential of [6]-paradol, it was orally administered to DMBA treated hamsters on alternate days from DMBA painting for 14 weeks. Results: We observed 100% tumor formation with marked levels of neoplastic changes and altered the expression of apoptotic associated gene (p53, bcl-2, caspase-3 and TNF-${\alpha}$) was observed in the DMBA alone painted hamsters as compared to control hamsters. Oral administration of [6]-paradol at a dose of 30 mg/kg b.wt to DMBA treated animals on alternative days for 14 weeks significantly reduced the neoplastic changes and improved the status of apoptosis associated gene expression. Conclusion: These observations confirmed that [6]-paradol acts as a tumor suppressing agent against DMBA induced oral carcinogenesis. We also conclude that [6]-paradol also effectively enhances apoptosis- associated gene expression in DMBA treated animals.