• Title/Summary/Keyword: Component development

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Characteristics of the inward current and its changes following fertilization in hamster eggs (햄스터 난자에서 관찰되는 내향전류의 성상과 수정후의 변화)

  • Han, Jae-hee;Hong, Seong-geun
    • Korean Journal of Veterinary Research
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    • v.38 no.2
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    • pp.280-289
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    • 1998
  • Voltage-sensitive ion channels contribute to establishment of the cell excitablity and the generation of the cellular function. At hamster oocytes in the primitive stage during developing process, an inward current elicited by voltage pulses was found to be carried mainly by $Ca^{2+}$. Even at present, $Ca^{2+}$ channels serve as the most probable route to pass this inward current but there is no evidence of the presence of this channels in eggs. To date, both the characteristic properties and the physiological role in the early stage of development remain unclear. Here we examined the characteristic properties of the inward current and changes in this currents at unfertilized oocytes, fertilized zygotes and two-cell embryos using whole-cell voltage clamp technique. The inward current carried reportedly by $Ca^{2+}$ was remained following removing external $Ca^{2+}$ but completely abolished by further replacement of impermeants such as tetramethylammonium ion ($TMA^+$) or $choline^+$ instead of $[Na^+]_0$. Tetrodotoxin did not affect on this inward current remained at $[Ca^{2+}]_0$-free condition. Removal of $Na^+$ ion out of the experimental solution clearly decreased the current. After adding 2mM $Ca^{2+}$ to the $Na^+$-free media, the inward current was restored. Interestingly, this current carried by either $Ca^{2+}$ or $Na^+$ was decreased by the reduction of intracellular $Cl^-$ concentration, or by $Cl^-$ channel blockers such as niflumic acid, DIDS and SITS. When $Cl^-$ concentration was lowered without changes in other ionic components, this inward current was reduced. At fertilized oocytes and two-cell embryos, the inward current carried by $Ca^{2+}$ and $Na^+$ was severely reduced. Also $Cl^-$ component could not be observed. From these results, the inward current is composed of $Ca^{2+}$, $Na^+$ and $Cl^-$ component, suggesting that the channel carrying this inward current is not selective specifically to $Ca^{2+}$. During early stage of development, the voltage-sensitive ion current seems not to contribute essentially to the cell cleavage and differentiation. The loss of $Cl^-$ component after fertilization suggests that $Cl^-$ may play a role in maintaining the viability of unfertilized ova.

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Development of the Hippocampal Learning Algorithm Using Associate Memory and Modulator of Neural Weight (연상기억과 뉴런 연결강도 모듈레이터를 이용한 해마 학습 알고리즘 개발)

  • Oh Sun-Moon;Kang Dae-Seong
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.43 no.4 s.310
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    • pp.37-45
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    • 2006
  • In this paper, we propose the development of MHLA(Modulatory Hippocampus Learning Algorithm) which remodel a principle of brain of hippocampus. Hippocampus takes charge auto-associative memory and controlling functions of long-term or short-term memory strengthening. We organize auto-associative memory based 3 steps system(DG, CA3, CAl) and improve speed of learning by addition of modulator to long-term memory learning. In hippocampal system, according to the 3 steps order, information applies statistical deviation on Dentate Gyrus region and is labelled to responsive pattern by adjustment of a good impression. In CA3 region, pattern is reorganized by auto-associative memory. In CAI region, convergence of connection weight which is used long-term memory is learned fast by neural networks which is applied modulator. To measure performance of MHLA, PCA(Principal Component Analysis) is applied to face images which are classified by pose, expression and picture quality. Next, we calculate feature vectors and learn by MHLA. Finally, we confirm cognitive rate. The results of experiments, we can compare a proposed method of other methods, and we can confirm that the proposed method is superior to the existing method.

Seismic Amplitude and Frequency Characteristics of Gas hydrate Bearing Geologic Model (가스 하이드레이트 지층 모델의 탄성파 진폭 및 주파수 특성)

  • Shin, Sung-Ryul;Lee, Sang-Cheol;Park, Keun-Pil;Lee, Ho-Young;Yoo, Dong-Geun;Kim, Young-Jun
    • Geophysics and Geophysical Exploration
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    • v.11 no.2
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    • pp.116-126
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    • 2008
  • In gas hydrate survey, seismic amplitude and frequency characteristics play a very important role in determining whether gas hydrate exists. According to the variation of source frequency and scatterer size, we study seismic amplitude characteristics using elastic modeling applied at staggered grids. Generally speaking, scattering occurs in proportion to the square of source frequency and the scatterer volume, which has an effect on seismic amplitude. The higher source frequency is, the more scattering occurs in gas hydrate bearing zone. Therefore, BSR is hardly observed in high frequencies. On the other side, amplitude blanking zone and BSR is clearly observed in lower frequencies although the resolution is poor as a whole. Seismic reflections traveling through free-gas layer below gas hydrate bearing zone decay so severely a high frequency component that a low frequency term is dominant. Amplitude anomaly of BSR result from high acoustic impedance contrast due to free-gas, which is a very crucial factor to estimate gas hydrate bearing zone. Seismic frequency analysis is carried out using wavelet transform method that frequency component could be decomposed with time variation. In application of wavelet transform to the seismic physical experiments data, we can observe that reflections traveling through air layer, which corresponds to the free-gas layer, decay a high frequency component.

A Study on the Boulder Stream of Granitoid in Korea (한국 화강암질암류 산지에서 발달하는 암괴류에 관한 연구)

  • Jeon, Young-Gweon
    • Journal of the Korean association of regional geographers
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    • v.6 no.2
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    • pp.71-82
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    • 2000
  • The purpose of this paper is to clarify geomorphic features and development on the boulder stream of granitoid in Korea. Considering the purpose and the method of this paper, three boulder streams are selected : Biseulsan(Mt. Biseul) boulder stream (Daegu city), Maneosan (Mt. Maneo) boulder stream(Gyeongnam province), Geumjeongsan(Mt. Geumjeong) boulder stream (Busan city). The boulder streams mentioned above are bigger in scale and more typical in shape than any other ones in the Korean Peninsula. The main results are summarized as follows. 1. The following are the main features of the boulder streams morphology : the mean gradient is $3{\sim}25^{\circ}$, the longer axes of the component boulders within the deposits averaged about 2m in length, the shapes of the component boulders may be both subangular and subrounded features. 2. The formation of the component boulders is associated with deep weathering of granitoid under warm humid conditions, and the downward movement of boulders occurred by solifluction and frost creep under periglacial conditions. 3. The geomorphic development stage of the boulder streams may be classified into four stages. These boulder streams come under fossil landform stage, the 4th stage ; evidence provided by lichens and weathering features indicate inactive or fossil landform. 4. In generally, boulder streams are well developed on shallow valley floors.

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Validity examination of the measurement of 3D visual fatigue using EEG (EEG 생체신호 기반 3D 시각피로 측정방법에 대한 타당화 연구)

  • Li, Hyung-Chul O.;Moon, Kyung-Ae
    • Science of Emotion and Sensibility
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    • v.15 no.1
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    • pp.17-28
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    • 2012
  • Recent development of 3D technologies made it possible that observers perceive 3D depth from two dimensional images. Despite this kind of technological development, when observers watch 3D display they experience 3D visual fatigue that they do not usually experience in real life. It is critical to measure visual fatigue in order to overcome the problem of 3D visual fatigue. The purpose of the present study was to develop a protocol to measure 3D visual fatigue based on an EEG signal and to examine its validity. The first experiment explored the possible ERP components that reflected visual fatigue in 2D and 3D conditions. The second experiment examined whether the feature of the component found in the first experiment was affected by the amount of binocular disparity. Both in Cz and Pz channels, the peak amplitude of P3 component was much lower in 3D rather than in 2D conditions, and it decreased as the amount of binocular disparity increased. The subjective 3D visual fatigue also increased with the amount of binocular disparity. These results imply that the peak amplitude of P3 component at Cz and Pz channels can be used as an index of 3D visual fatigue.

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Investigation of the body distribution of load pressure and virtual wear design according to the corset type harness (코르셋 타입 하네스의 신체 하중압력 분포 측정 및 가상착의 적용)

  • Kwon, MiYeon;Choi, Sola;Kim, Juhea
    • Journal of the Korea Fashion and Costume Design Association
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    • v.23 no.3
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    • pp.1-10
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    • 2021
  • Harnesses are used in a variety of industries, such as rescue operations, medicine, and entertainment. However, conventional harnesses have problems as they are uncomfortable to wear and causes continuous pain. Therefore, in this study, the load and pressure applied to the body in the flying state when using a conventional harness were measured in real time and the distribution change was observed. Load and pressure were measured using a modified corset harness, a pressure sensor, and a human mannequin to measure the maximum and average pressure on the waist. As a result, it was confirmed that the load concentrated on the waist in the flying state was 104 N, and the pressure was applied to the left and right sides was 800 kPa or greater. The pressure distribution showed a pressure of 3-45 kPa in 73% in all measurable pressures. The results of the load and pressure distribution are presented as basic data for improving the wearability and reducing the discomfort of harnesses in the future, aid in the development of a harnesses that can minimize discomfort for various activities, and increase the concentration on experiential activities. In addition, using the CLO 3D program, which is a 3D virtual wearing system, a harness was put on a virtual model, and the compression level was checked and compared with the actual pressure distribution. As a result of comparing the measured pressure values in the flying state with the clothing pressure wearing the harness in the CLO 3D program, the total pressure value was found to be about 68% of the actual measured value. This helps develop a harness that can minimize discomfort during activities by predicting the load and pressure on the body by first applying new designs to a virtual wearing system during development. These new harness patterns can solve the problems of conventional harnesses.

Development of Novel Sulforaphane Contained-composition to Increase Antioxidant and Whitening Effects (항산화와 미백효과를 증진시킨 새로운 Sulforaphane 함유 혼합 조성의 개발)

  • Lee, Ji Hye;Choi, Kang Hyun;Park, Young Kum;Kim, Eung-Gook;Shin, Eun-Young
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.44 no.4
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    • pp.437-445
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    • 2018
  • In this study, we analyzed two components, sulforaphane and PF-3758309 to prove that the mixed composition of them has more effective antioxidant and whitening functions compared to each component. We analyzed the cellular toxicity of each component and also the mixed composition to find the safe concentration level for cell viability. From the single component treatment, we discovered that sulforaphane was safe up to $10{\mu}M$, and PF-3758309 up to 100 nM. Combination treatment of $10{\mu}M$ sulforaphane and 1 nM PF-3758309 did not affect the cell viability. The LPS-stimulated NO generation was significantly reduced by the mixed composition of sulforaphane and PF-3758309. Melanogenesis by ${\alpha}$-melanocyte stimulating hormone (${\alpha}$-MSH) was also inhibited by the mixed composition. In order to confirm the possibility as the cosmetic material, we carried out clinical studies for the mixed composition samples. Skin safety evaluation using patch test was judged to be unstimulated, skin whitening effect was increased, and melanin deposition was suppressed by treatment of mixed composition samples. These results provide us with the opportunity for applying it into the development of new functional cosmetics.

Design of very fast acting fuse element using the Ag-Cu alloy (Ag-Cu 합금을 이용한 매우 빠른 동작 특성의 퓨즈 엘리멘트 설계)

  • Kim, Eun-Min;Lee, Seung-Hwan;Cho, Dae-Kweon;Kim, Shin-Hyo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.8
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    • pp.1070-1074
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    • 2014
  • With the development of the electronics industry and widespread supply of many different electrical appliances, the factors of the electrical fires are also diversified. For this reason, the fuse, safety-critical component, needs accurate and stable operating characteristics for preventing various fire factor, and also needs various operating characteristics. Especially when the all electrical resistance are dropped by internal short of circuit, high current inrushes and makes the fire. In order to prevent this, very fast acting fuses should be applied. However, existing very fast acting characteristics fuse has less wire dimension of element Ag100% metal than that of fast acting fuse, and it is made of plating with low melting point metals, so it satisfy very fast acting but it can't satisfy durability and safety. For this reason, in this study, through the analyzing fusing characteristics of Ag-Cu alloy composition, the new alloy composition, which implement to very fast acting fuse without decrease of fuse elements dimension, is suggested. And this study classify the operating characteristics changes, a resistance change, and the rated current of the fuse in the overall composition change of Ag-Cu alloying. and it can be utilized for designing fuse.

Comparison of Quality Characteristics of Melania snails in Korea (한국산 다슬기의 식품학적 성분 및 품질특성)

  • Lim, Chi-Won;Kim, Yeon-Kye;Kim, Dae-Hee;Park, Jin-Il;Lee, Moon-Hee;Park, Hee-Yeon;Jang, Mi-Soon
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.6
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    • pp.555-560
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    • 2009
  • To identify the food characteristics of seven melania snail species in Korea, the detailed proximate, fatty/amino acid, mineral composition and chlorophyll contents were investigated. The content ranges of moisture, crude protein, crude lipid and ash were 70.1-81.0%, 11.6-16.9%, 0.4-1.6% and 1.9-3.4%, respectively. K. nadifila showed the significant mineral contents Fe, P, Ca than other species. Total Chlorophyll level was highest in K. globus ovalis ($1.2\pm0.2$ mg/g). The major fatty acids were 16:0, 22:1, 20:1, 18:1, 20:5 and 22:6 were identified as small amounts (1.0-3.3%) of total fatty acids. Citrulline was shown to be the major free amino acids (20.4-53.1%).

A Review for Non-linear Models Describing Temperature-dependent Development of Insect Populations: Characteristics and Developmental Process of Models (비선형 곤충 온도발육모형의 특성과 발전과정에 대한 고찰)

  • Kim, Dong-Soon;Ahn, Jeong Joon;Lee, Joon-Ho
    • Korean journal of applied entomology
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    • v.56 no.1
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    • pp.1-18
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    • 2017
  • Temperature-dependent development model is an essential component for forecasting models of insect pests as well as for insect population models. This study reviewed the nonlinear models which explain the relationship between temperature and development rate of insects. In the present study, the types of models were classified largely into empirical and biophysical model, and the groups were subdivided into subgroups according to the similarity of mathematical equations or the connection with original idea. Empirical models that apply analytical functions describing the suitable shape of development curve were subdivided into multiple subgroups as Stinner-based types, Logan-based types, performance models and Beta distribution types. Biophysical models based on enzyme kinetic reaction were grouped as monophyletic group leading to Eyring-model, SM-model, SS-mode, and SSI-model. Finally, we described the historical development and characteristics of non-linear development models and discussed the availability of models.