• Korean Journal of Fisheries and Aquatic Sciences
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• v.55 no.2
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• pp.218-223
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• 2022

Cholesterol is an essential component for maintaining health; however, excessive consumption can lead to diseases. Thus, continuous monitoring of cholesterol content is important in food research. The cholesterol analysis method used in Korea follows the Korean Food Standards Codex. As this method uses gas chromatography, derivatization of the sample is required, and analysis time is more than 30 min. Kim developed a new method using liquid chromatography; however saponification by the non-heat saponification method is insufficient. To address these limitations, a new cholesterol analysis method was developed and verified. The correlation coefficients for the cholesterol standard (STD) were maintained above 0.99. The limit of detection and limit of quantitation of cholesterol STD were 2.41 ㎍/mL and 7.31 ㎍/mL, respectively. The accuracies for cholesterol were 92.21-99.02%. The developed analytical method was also verified using three standard reference materials, and their accuracies were 93.71-97.09%. In addition, the cholesterol content of fishes was analyzed, and the values were compared with those recorded by the United States Department of Agriculture. Our results suggest that this method could be used as a new analytical method for cholesterol in seafood.

• Journal of The Korean Society of Agricultural Engineers
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• v.64 no.5
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• pp.67-77
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• 2022

Recently, the trend in structural analysis and design is moving towards the development of reliable system. The reliability-based method defines various limit states related to usability and failure, thereby enabling multiple levels of design according to the importance of a structure. Meanwhile, an actual structure is composed of a set of several elements, and particularly, a frame type is composed of a system in which the members are connected each other. At this time, the actual connection between members is in a semi-rigid condition, not in complete rigid or hinged. This semi-rigid is found in several structures, especially in agricultural facilities designed with lightweight materials. In this study, a system reliability analysis technique for frame structure was established, and applied to an analysis of the semi-rigid connection. Various conditions of correlation were applied to reflect the connectivity between members, and through this, the limitations of existing structural analysis method and the behavioral characteristics of structure were analyzed. The failure probability of the frame member component and the overall structure system was significantly different in consideration of the semi-rigid connection. In addition, it was evaluated that the behavior of structure can be more accurately analyzed if the correlation according to the position of members in a system is further investigated.

• KNOM Review
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• v.23 no.1
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• pp.51-62
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• 2020

Open IoT platform that shares communication infrastructure and provides cloud resources can flexibly reduce development period and cost of smart service. In this paper, as an open IoT platform, we propose a virtual IoT system based on edge computing that implements a virtual IoT device for a physical IoT device and allows service developers to interact with the virtual device. A management server in the edge cloud, near the IoT physical device, manages the creation, movement, and removal of virtual IoT devices corresponding to the physical IoT devices. This paper define the operations of the management server, the physical IoT device, and the virtual IoT device, which are major components of the virtual IoT system, and design the communication protocol required to perform the operations. Finally, through simulations, this paper evaluate the performance of the edge computing based virtual IoT system by confirming that each component performs the defined states and operations as designed.

• Journal of Ocean Engineering and Technology
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• v.36 no.5
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• pp.340-352
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• 2022

This article presents a modeling method for the uncorrelated measurement error of the ultra-short baseline (USBL) acoustic positioning system for aiding navigation of underwater vehicles. The Mahalanobis distance (MD) and principal component analysis are applied to decorrelate the errors of USBL measurements, which are correlated in the x- and y-directions and vary according to the relative direction and distance between a reference station and the underwater vehicles. The proposed method can decouple the radial-direction error and angular direction error from each USBL measurement, where the former and latter are independent and dependent, respectively, of the distance between the reference station and the vehicle. With the decorrelation of the USBL errors along the trajectory of the vehicles in every time step, the proposed method can reduce the threshold of the outlier decision level. To demonstrate the effectiveness of the proposed method, simulation studies were performed with motion data obtained from a field experiment involving an autonomous underwater vehicle and USBL signals generated numerically by matching the specifications of a specific USBL with the data of a global positioning system. The simulations indicated that the navigation system is more robust in rejecting outliers of the USBL measurements than conventional ones. In addition, it was shown that the erroneous estimation of the navigation system after a long USBL blackout can converge to the true states using the MD of the USBL measurements. The navigation systems using the uncorrelated error model of the USBL, therefore, can effectively eliminate USBL outliers without loss of uncontaminated signals.

• Korean Journal of Clinical Pharmacy
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• v.32 no.4
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• pp.352-361
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• 2022

Objective: This study aimed to analyze the important medical adverse events (IMEs) of cyclosporine and tacrolimus using the reports in US FDA adverse event reporting system (FAERS) and to detect related signals. Methods: The FAERS database was used to analyze the IMEs reported for cyclosporine or tacrolimus during 2017-2021. Reporting odds ratio (ROR) and information component were used to analyze signals for adverse events of both drugs. It was investigated whether the detected signals were present on drug labels in Korea and the United States. Results: Among the total 24,688 reports, the reports on tacrolimus accounted 75.8%. Mean age of the patients was 47.9 years old and median number of adverse events was 2.0 per report. The number of patients hospitalized for adverse events was 7,979 (25.3%). Among the adverse reactions reported on the cyclosporine and tacrolimus, 576 and 1,363 events were detected as signals for cyclosporine and tacrolimus, respectively, and of these, IMEs accounted for 44.8 and 59.2%, respectively. The IMEs related with infections/infestations, renal/urinary disorders, and blood and lymphatic system disorders were reported frequently for both drugs. The most frequently detected IMEs were renal impairment for cyclosporine and acute kidney injury for tacrolimus. Among the top 3 IMEs for each reported SOC for cyclosporine and tacrolimus, 9 and 2 unexpected adverse events were identified, respectively. Conclusion: This study identified the IMEs and signals of cyclosporine and tacrolimus, and detected unidentified adverse events in a drug information database.

• International Journal of Advanced Culture Technology
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• v.11 no.3
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• pp.277-296
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• 2023

The South Korean ethnic diaspora US lobby shows efficacy as an interest group in generating influence in American foreign and domestic public policy making. The persuasive portrayal of South Korea as a critical Cold War US ally reinforced US amenability to pro-South Korea lobbying. Also, the South Korean US diaspora is a comparatively recent immigrant group, thus its lingering resistance to assimilation facilitates its political mobilization to lobby the US government. One source of this influence includes the foundational legacy of proselytizing Western and particularly American religious social movement representatives in Korean religiosity and society. US protestant Christianity acquired a strong public association with emerging Korean nationalism in response to Japanese imperialism and occupation. Hostility towards Japanese colonialism followed by the threat from Soviet-sponsored, North Korean Communism meant Christianity did not readily become a cultural symbol of excessive external, US interference in South Korean society by South Korean public opinion. The post-Cold War shift in US foreign policy towards targeting so-called rogue state vestiges of the Cold War including North Korea enhanced further South Korea's influence in Washington. Due to essential differences in the perceived historical role of American influence, extrapolation of the South Korean development model is problematic. US hegemony in South Korea indicates that perceived alliance with national self-determination constitutes the core of soft power appeal. Civilizational appeal per se in the form of religious beliefs are not critically significant in promoting American polity influence in target polities in South Korea or, comparatively, in the Middle East. The United States is a perceived opponent of pan-Arab nationalism which has trended towards populist Islamic religious symbolism with the failure of secular nationalism. The pronounced component of evangelical Christianity in American core community nationalism which the Trump campaign exploited is a reflection of this orientation in the US.

• Earthquakes and Structures
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• v.24 no.3
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• pp.217-235
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• 2023

Orthogonal pairs of rollers on concave beds (OPRCB) are a low-cost, low-tech rolling-based isolating system, whose high efficiency has been shown in a previous study. However, seismic performance of OPRCB isolators has only been studied in the two-dimensional (2D) state so far. This is while their performance in the three-dimensional (3D) state differs from that of the 2D state, mainly since the vertical accelerations due to rollers' motion in their beds, simultaneously in two orthogonal horizontal directions, are added up and resulting in bigger vertical inertia forces and higher rolling resistance. In this study, first, Lagrange equations were used to derive the governing equations of motion of the OPRCB-isolated buildings in 3D. Then, some regular shear-type OPRCB-isolated buildings were considered subjected to three-component excitations of far- and near-source earthquakes, and their responses were compared to those of their fixed-base counterparts. Finally, the effects of more realistic modeling and analysis were examined by comparing the responses of isolated buildings in 2D and 3D states. Response histories were obtained by the fourth-order Runge-Kutta-Nystrom method, considering the geometrical nonlinearity of isolators. Results reveal that utilizing the OPRCB isolators effectively reduces the acceleration response, however, depending on the system specifications and earthquake characteristics, the maximum responses of isolated buildings in the 3D state can be up to 40% higher than those in the 2D state.

• Korean Journal of Clinical Pharmacy
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• v.32 no.1
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• pp.1-7
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• 2022

Objective: The purpose of this study was to detect signals of Adverse Events (AEs) after varenicline treatment using spontaneous AEs reporting system in Korea. Methods: This study was conducted by Korea Institute of Drug Safety and Risk Management-Korea Adverse Event Reporting System Database (KIDS-KD) reported from January 2013 to December 2017 through Korea Adverse Event Reporting System. Signals of varenicline that satisfied the data-mining indices, proportional reporting ratio, reporting odds ratio and information component were defined. The detected signals were checked whether they included in drug labels in South Korea and United States of America (USA). Results: A total number of drug AE reports associated with all drugs in the KIDS-KD reported between January 2013 and December 2017 was 2,665,429. Among them, the number of AE reports associated with varenicline was 1,398. Eighteen meaningful signals of varenicline were detected that satisfied with the criteria of data-mining indices. Finally, two signals such as hypotonia, incorrected dose administered were not included in the drug labels. Conclusion: New AE signals of varenicline that were not listed on the drug labels in South Korea and USA were detected. However, further pharmacoepidemiological studies such as randomized controlled trial are needed to evaluate the causality of the signals of varenicline.

• Journal of the Korea Computer Graphics Society
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• v.28 no.4
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• pp.1-11
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• 2022

The Skinned Multi-Person Linear Model (SMPL) is the most widely used parametric 3D Human Model optimized and learned from CAESAR, a 3D human scanned database created with measurements from 3,800 people living in United States in the 1990s. We point out the lack of racial diversity of body types in SMPL and propose K-SMPL that better represents Korean 3D body shapes. To this end, we develop a fitting algorithm to estimate 2,773 Korean 3D body shapes from Korean body measurement data. By conducting principle component analysis to the estimated Korean body shapes, we construct K-SMPL model that can generate various Korean body shape in 3D. K-SMPL model allows to improve the fitting accuracy over SMPL with respect to the Korean body measurement data. K-SMPL model can be widely used for avatar generation and human shape fitting for Korean.

• International conference on construction engineering and project management
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• 2013.01a
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• pp.390-390
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• 2013

Use of recycled aggregates in portland cement concrete construction can offer benefits associated with both economy and sustainability. Testing performed to date indicates that RBMA can be used as a 100% replacement for conventional coarse aggregate in concrete that exhibits acceptable mechanical properties for use in structural and pavement elements, including satisfactory performance in some durability tests. RBMAC is currently not used in any type of construction in the United States. However, use of RBMAC could become a viable construction strategy as sustainable building practices become the norm. Rating systems such as LEED offer points for reuse of building materials (particularly on-site) and use of recycled materials. If renovations at an existing facility call for the demolition of existing brick masonry constructions, the rubble could be included as RBMA in new concrete pavement, sidewalks, or curb and gutter. Other potential uses for RBMAC could include those in the precast concrete industry, particularly in architectural precast concrete applications. In addition to providing acceptable strength and economy, the color of RBMA could be an attractive component of architectural precast concrete panels or other façade components. This paper explores the feasibility of use of RBMAC in several types of sustainable construction initiatives, based upon the findings of previous work with RBMAC produced from construction and demolition waste from a case study site. Guidance for obtaining and using RBMA is presented, along with a summary of material properties of RBMAC that will be useful to construction professionals.