• Journal of Korean Society on Water Environment
• /
• v.35 no.1
• /
• pp.35-42
• /
• 2019

Urbanization has led to extreme changes in land use on urban watersheds. Most cities are becoming residential, commercial and industrial areas, making infiltration and storage of rainfall less favorable. The demand for LID (Low Impact Development) technology is increasing in order to mitigate this water cycle distortion and return to existing hydrological conditions. The LID technique is effective in reducing runoff by permeating the urban impervious area. However, considering the limit of the installation area and the financial requirement of the installation, there is not much research on the linkage of each LID component technology for optimum efficiency according to the appropriate scale. In this study, the effects of the LID facilities applied to the target site were simulated using the SWMM model, suggesting the optimal linkage method considering interconnectivity, and applying the effects as an existing installation of individual facilities. The water balance at the time of application of the LID technology, short-term and long-term rainfall event were compared. Also, the individual application and the linkage application were compared with each other. If each component technology has sufficient processing size, then linkage application is more effective than individual application.

• Journal of The Korean Society of Integrative Medicine
• /
• v.8 no.4
• /
• pp.1-11
• /
• 2020

Purpose : The purpose of this meta-analysis was to examine the effects of microcurrent on inflammatory musculoskeletal diseases. Methods : Domestic databases (RISS, NDSL, KISS, DBpia, and Kmbase) were searched for studies that conducted clinical trials associated with microcurrent and its impact on inflammatory musculoskeletal diseases. A total of 606 studies published between 2002 and 2019 were identified, with 8 studies satisfying the inclusion data. The studies were classified according to patient, intervention, comparison, and outcome (PICO). The search outcomes were items associated with blood component, pain, and function. The 8 studies that were included in the study were evaluated using R meta-analysis (version 4.0). The quality of 7 randomized control trials was evaluated using Cochrane risk of bias (ROB). The quality of 1 non-randomized control trial was evaluated using risk of bias assessment tool for non-randomized studies (RoBANS). Effect sizes were computed as the corrected standard mean difference (SMD). A random-effect model was used to analyze the effect size because of the high heterogeneity among the studies. Egger's regression test was carried out to analyze the publishing bias. Results : The following factors had a large effect size involving microcurrent on inflammatory musculoskeletal diseases: blood component (Hedges's g=-2.46, 95 % CI=-4.20~-0.73), pain (Hedges's g=3.51, 95 % CI=2.44~4.77), and function (Hedges's g=3.06, 95 % CI: 1.53~4.58). Except for function (t=1.572, p=.191), Egger's regression test showed that the publishing bias had statistically significant differences. Conclusion : This study provides evidence for the effectiveness of microcurrent on inflammatory musculoskeletal diseases in terms of blood component, pain, and function. However, due to the small sample sizes used in the included studies, the results of our study should be interpreted cautiously, especially considering the publishing bias.

• Wind and Structures
• /
• v.36 no.4
• /
• pp.221-236
• /
• 2023

The lateral component of turbulence and the vortices shed in the wake of a structure result in introducing dynamic wind load in the acrosswind direction and the resulting level of motion is typically larger than the corresponding alongwind motion for a dynamically sensitive structure. The underlying source mechanisms of the acrosswind load may be classified into motion-induced, buffeting, and Strouhal components. This study proposes a frequency domain framework to decompose the overall load into these components based on output-only measurements from wind tunnel experiments or full-scale measurements. First, the total acrosswind load is identified based on measured acceleration response by solving the inverse problem using the Kalman filter technique. The decomposition of the combined load is then performed by modeling each load component in terms of a Bayesian filtering scheme. More specifically, the decomposition and the estimation of the model parameters are accomplished using the unscented Kalman filter in the frequency domain. An aeroelastic wind tunnel experiment involving a tall circular cylinder was carried out for the validation of the proposed framework. The contribution of each load component to the acrosswind response is assessed by re-analyzing the system with the decomposed components. Through comparison of the measured and the re-analyzed response, it is demonstrated that the proposed framework effectively decomposes the total acrosswind load into components and sheds light on the overall underlying mechanism of the acrosswind load and attendant structural response. The delineation of these load components and their subsequent modeling and control may become increasingly important as tall slender buildings of the prismatic cross-section that are highly sensitive to the acrosswind load effects are increasingly being built in major metropolises.

• Natural Product Sciences
• /
• v.13 no.3
• /
• pp.258-262
• /
• 2007

The antifungal activity of the essential oil fraction from Thymus magus, and its major component thymol, against Candida albicans was investigated in vitro and in vivo. The combined effects of the oils and clotrimazole, a commonly used antifungal drug for treatment of external candidiasis, were evaluated in this study. In experimental vaginal candidiasis the essential oil fraction of T. magnus resulted in relatively milder inhibition of fungal growth following the inoculation of test mice compared to clotrimazole. However, new fungal growth was not detected up to 12 days after cessation of treatment. In contrast, in a similar experiment using clotrimazole, C. albicans was detected in the $12^{th}$ day post-treatment with the sample. This result indicates that T. magnus oil could be a promising drug to control vaginal candidiasis. In checkerboard titer tests, the combination of clotrimazole with the essential oil fraction of T. magus or T. quinquecostatus resulted in significant synergism, with FIC indices between 0.14 and 0.27 against C. albicans, while clotrimazole combined with thymol, the major component of these oils, produced only an additive effect, with FIC indices ranging between 0.50 and 1.00. Thus, the prominent synergistic effects of clotrimazole combined with T. magus essential oil indicate that these compounds may be an effective treatment for C. albicans infections.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.13 no.3
• /
• pp.178-185
• /
• 2005

Crack tip displacement is originated by tensile stress component, s and shear stress component, t on pure Mode I and pure Mode II. The crack tip displacement(CTD) depends on combined types of different two stress components under mixed-mode loading conditions (MMLC). Thus, the analysis of crack tip displacement must be CTD vector, dv which is composition of ds and dt under MMLC. In this paper, various effects of MMLC on the crack closure are studied experimentally. The crack closure magnitude is calculated from the information of crack tip displacement under MMLC. This information has been obtained from the high resolution optical microscope in direct observations of crack displacement behavior at the crack tip. Observed crack tip displacement is analyzed by using CTD vector to determine crack opening load. The various effects of MMLC on the crack closure are explained using crack opening ratio with crack length and mode mixture. The effective stress intensity factor considering crack closure is also discussed.

• Journal of Nutrition and Health
• /
• v.38 no.2
• /
• pp.104-111
• /
• 2005

Tumor invasion is composed of four steps: cell adhesion to the extracellular matrix, degradation of the extracellular matrix components, tumor cell motility followed by cell detachment. Matrix metalloproteinases (MMPs) are important proteinases that associated with degradation of matrix component. Epigallocatechin gallate (EGCG) is a major polyphenotic constituent of green tea. In the study, we examined the anti-invasive and MMP activity suppression effects of EGCG in MDA-MB-231 human breast cancer cells. MDA-MB-23l human breast cancer cells were cultured with various concentrations 0 - 100 μM of EGCG. EGCG significantly inhibited the cell adhesion to the fibronectin. Cell motility through gelatin filter and invasion to Matrigel were inhibited dose-dependently by EGCG treatment. EGCG also inhibited the activities of MMP-2, -9 and the amount of MMP-9 (α = 0.05). Therefore, EGCG may contribute to the potential beneficial food component to prevent the invasion and metastasis in breast cancer. (Korean J Nutrition 38(2): 104～111, 2005)

• Journal of Pharmacopuncture
• /
• v.8 no.3
• /
• pp.71-77
• /
• 2005

Objective : Literary investigation of existing data was conducted to verify effects of Moschus and its herbal acupuncture, and determine quality management through component analysis. Results : Following results were obtained through literary investigation. 1. Deer musk (Moschus) is dried navel gland secretions of the adult male musk deer. 2. Moschus is known to be effective for treating various febrile diseases, to revive senses, heart and abdominal pain, complications from cerebral hemorrhage, angina, and others. 3. Single dosage of Moschus is between $0.03{\sim}0.1g$ and should not exceed 1g. Normally taken as powder or pill and may be used externally. 4. Moschus also has protective effects for the liver cells, and experiments revealed possible efficacies for hyperlipidemia, brain damage, hypertension, and etc. 5. For herbal acupuncture usage, Fel Ursi, Bezoar Bovis, and Moschus are used as a mixture (BUM), and it's known to be effective for protecting the liver and treating arthritis. 6. For component analysis of Moschus, aromatic matter 'muscone' should be used as a standard matter.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.27 no.5
• /
• pp.724-733
• /
• 2003

Fatigue design rules for welds in the ASME Boiler and Pressure Vessels Code are based on the use of Fatigue Strength Reduction Factors(FSRF) against a code specified fatigue design curve generated from smooth base metal specimens without the presence of welds. Similarly, stress intensification factors that are used in the ASME B3l.1 Piping Code are based on component S-N curves with a reference fatigue strength based on straight pipe girth welds. But the determination of either the FSRF or stress intensification factor requires extensive fatigue testing to take into account the stress concentration effects associated with various types of component geometry, weld configuration and loading conditions. As the fatigue behavior of welded joints is being better understood, it has been generally accepted that the difference in fatigue lives from one type of weld to another is dominated by the difference in stress concentration. However, general finite element procedures are currently not available for effective determination of such stress concentration effects. In this paper, a mesh-insensitive structural stress method is used to re-evaluate the S-N test data, and then more effective method is proposed for pressure vessel and piping fatigue design.

• Journal of the Korean Society of Physical Medicine
• /
• v.5 no.4
• /
• pp.569-576
• /
• 2010

Purpose : This study was aimed at determining the effects of community-based exercise program to improve leg muscle strength and balance for elderly women. Methods : This study was nonequivalent control group pre-post test design. Subjects were assigned to two different groups(exercise group=11, control group=7). Exercise group performed community-based exercise program for 8 weeks. Outcome measures included leg muscle strength, balance, walking velocity, activities of daily living(ADL), exercise self-efficacy and health-related quality of life(QoL). The collected data analyzed by independent t-test and paired t-test. Results : Leg muscle strength, walking velocity and mental component summary(QoL) were significantly improved in the exercise group. But balance and exercise self-efficacy were significantly worsened in the control group. There were no significant difference between groups after 8 weeks of community-based exercise. Conclusion : These results suggested that the community-based exercise program is effective for elderly women in improving leg muscle strength, walking velocity and mental component summary(QoL).

• Proceedings of the Technology Innovation Conference
• /
• 2006.02a
• /
• pp.78-102
• /
• 2006

Networks, services and industries have been converging with the advent of digital convergence by technology advancements of digitalization, broadband and interactivity in the areas of information-communication and broadcasting technologies. Especially, this convergence of technology and market has been blurring the boundary of telecommunication and broadcasting sectors, and the severe competition seems to be inevitable due to the lack of the differentiation in broadcasting media and contents. In this study, we regard the competition phenomenon in the digital convergence between telecommunication and broadcasting as the platform competition in two-sided markets which have been actively studied since 2000, and analyzed it using modified Hotelling's location model. According to the analysis of platform competition on the effects of the differentiation of platform (t) , killer component $(\mu)$ and component compatibility $(\theta)$ , it is shown that two differentiated platforms are simultaneously used in case of the decrease of substitution effects, and the profit of platform with killer contents is increased, but the profit of platforms with higher compatibility is decreased. The policy implication is that it is especially necessary to modify the policy and regulation on media contents considering the growing competition in media. On the other hand, differentiated and reasonable policy is required to make fair competition and active market environment.