• Journal of the Optical Society of Korea
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• v.16 no.4
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• pp.425-431
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• 2012

Utilizing the three-dimensional Snyder-Mitchell model with a PT-symmetric potential, we study the influence of PT symmetry on beam propagation in strongly nonlocal nonlinear media. The complex Coulomb potential is used as the PT-symmetric potential. A localized spatiotemporal accessible soliton solution of the model is obtained. Specific values of the modulation depth for different soliton parameters are discussed. Our results reveal that in these media the localized solitons can exist in various shapes, such as single-layer and multi-layer disk-shaped structures, as well as vortex-ring and necklace patterns.

• Journal of Power Electronics
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• v.19 no.1
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• pp.168-178
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• 2019

Discrete space vector modulation (DSVM) is an effective method to improve the steady-state performance of the finite control set predictive control for permanent magnet synchronous motor drive systems. However, it requires complex computations due to the presence of numerous virtual voltage vectors. This paper proposes an improved finite control set model-free predictive control using DSVM to reduce the computational burden. First, model-free deadbeat current control is used to generate the reference voltage vector. Then, based on the principle that the voltage vector closest to the reference voltage vector minimizes the cost function, the optimal voltage vector is obtained in an effective way which avoids evaluation of the cost function. Additionally, in order to implement double-objective control, a two-level decisional cost function is designed to sequentially reduce the stator currents tracking error and the inverter switching frequency. The effectiveness of the proposed control is validated based on experimental tests.

• Molecules and Cells
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• v.42 no.5
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• pp.379-385
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• 2019

Non-coding RNAs (ncRNAs) comprise various RNA species, including small ncRNAs and long ncRNAs (lncRNAs). ncRNAs regulate various cellular processes, including transcription and translation of target messenger RNAs. Recent studies also indicate that ncRNAs affect organismal aging and conversely aging influences ncRNA levels. In this review, we discuss our current understanding of the roles of ncRNAs in aging and longevity, focusing on recent advances using the roundworm Caenorhabditis elegans. Expression of various ncRNAs, including microRNA (miRNA), tRNA-derived small RNA (tsRNA), ribosomal RNA (rRNA), PIWI-interacting RNA (piRNA), circular RNA (circRNA), and lncRNA, is altered during aging in C. elegans. Genetic modulation of specific ncRNAs affects longevity and aging rates by modulating established aging-regulating protein factors. Because many aging-regulating mechanisms in C. elegans are evolutionarily conserved, these studies will provide key information regarding how ncRNAs modulate aging and lifespan in complex organisms, including mammals.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.9
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• pp.2942-2960
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• 2022

The core of cognitive radio is the problem concerning intelligent decision-making for communication parameters, the objective of which is to find the most appropriate parameter configuration to optimize transmission performance. The current algorithms have the disadvantages of high dependence on prior knowledge, large amount of calculation, and high complexity. We propose a new decision-making model by making full use of the interactivity of reinforcement learning (RL) and applying the Q-learning algorithm. By simplifying the decision-making process, we avoid large-scale RL, reduce complexity and improve timeliness. The proposed model is able to find the optimal waveform parameter configuration for the communication system in complex channels without prior knowledge. Moreover, this model is more flexible than previous decision-making models. The simulation results demonstrate the effectiveness of our model. The model not only exhibits better decision-making performance in the AWGN channels than the traditional method, but also make reasonable decisions in the fading channels.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.159-164
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• 2023

Ferroptosis is a type of regulated cell death recently discovered, characterized by the accumulation of iron-dependent lipid peroxides in the cell membrane, and it involves a complex network of signaling pathways, including iron metabolism, lipid peroxidation, and redox regulation. The dysregulation of these pathways can lead to the induction of ferroptosis and the development of liver diseases, such as alcoholic liver disease, non-alcoholic fatty liver disease, viral hepatitis, and liver cancer. Studies have demonstrated that targeting key molecules involved in iron metabolism, lipid peroxidation, and redox regulation can reduce liver injury and improve liver function in different liver diseases by inhibiting ferroptosis. Thus, modulation of ferroptosis presents a promising therapeutic target for treating liver diseases. However, further research is required to gain a more comprehensive understanding of the mechanisms underlying the role of ferroptosis in liver diseases and to develop more effective and targeted treatments.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.2
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• pp.215-223
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• 2017

The effects of acidic pH on several voltage-dependent ion channels, such as voltage-dependent $K^+$ and $Ca^{2+}$ channels, and hyperpolarization-gated and cyclic nucleotide-activated cation (HCN) channels, were examined using a whole-cell patch clamp technique on mechanically isolated rat mesencephalic trigeminal nucleus neurons. The application of a pH 6.5 solution had no effect on the peak amplitude of voltage-dependent $K^+$currents. A pH 6.0 solution slightly, but significantly inhibited the peak amplitude of voltage-dependent $K^+$ currents. The pH 6.0 also shifted both the current-voltage and conductance-voltage relationships to the depolarization range. The application of a pH 6.5 solution scarcely affected the peak amplitude of membrane currents mediated by HCN channels, which were profoundly inhibited by the general HCN channel blocker $Cs^+$ (1 mM). However, the pH 6.0 solution slightly, but significantly inhibited the peak amplitude of HCN-mediated currents. Although the pH 6.0 solution showed complex modulation of the current-voltage and conductance-voltage relationships, the midpoint voltages for the activation of HCN channels were not changed by acidic pH. On the other hand, voltage-dependent $Ca^{2+}$ channels were significantly inhibited by an acidic pH. The application of an acidic pH solution significantly shifted the current-voltage and conductance-voltage relationships to the depolarization range. The modulation of several voltage-dependent ion channels by an acidic pH might affect the excitability of mesencephalic trigeminal nucleus neurons, and thus physiological functions mediated by the mesencephalic trigeminal nucleus could be affected in acidic pH conditions.

• Korean Institute of Interior Design Journal
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• v.19 no.6
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• pp.100-111
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• 2010

'Pattern' is the term that is frequently used in the aspects of history, society, and science. It always appears in the remains or relics of the age of civilization when recording was started, and its evaluation and value differ by time. Patterns in the ancient civilization were symbolic, social, and spatially crucial. However, after the modernization, they were considered to be immoral and unnecessary, so the range of their significance came to reduce. Due to the development of science, ornament patterns lost the limitation of its range of use along with new interpretation of them. Especially with the advent of new scientific theories such as the evolution theory from the biological aspect, quantum mechanics, and super string theory, morphological possibilities more than the human scale perceived by men came to be discovered. Living organisms maintain their lives through patterns, structures, and processes in order to produce a system alive. Among them, patterns are the organization of relations determining the characteristics of the system. The present patterns may correspond to this meaning. The pattern in a space is the matter of how to relate the components after all. In a space, however, there are numerous components mingled with one another. If these tasks are conducted as analogue work, it will take a lot of time and effort. However, if digital media are utilized to perform the tasks like analysis, generation, or fabrication, it will produce a result with higher precision and efficiency. In this sense, parametric modeling is quite useful media. Opening morphological variation, it realizes more possibilities, connects conveniently the relations between complex components composing a space, and helps produce creative patterns.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.9C
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• pp.1279-1288
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• 2004

In this paper, the DMR(Digital Microwave Radio) system-based OFDM(Orthogonal Frequency Division Multiplexing) scheme in microwave channel environments has been proposed and system performances have been evaluated. The existing single carrier DMR system has a complex system structure due to using high-level QAM(Quadrature Amplitude Modulation) modulation scheme and so charmel capacity is limited by sensitive effects from fading. Therefore, in the proposed DMR system, it uses that the OFDM scheme for enhancement of fading distortion and also uses that the band-limited pulse shaping filter instead of windowing for no additional data such as GI/GB and for using efficient of IFFT/FFT block. The performance of OFDM/QPSK-DMR system and single carrier DMR system are analysed by computer simulation using two-ray model under the microwave channel environments The computer simulation results confirm that the fade margin of the proposed OFDM/QPSK-DMR system is highly increased as the number of sub-carriers is larger.

• The Transactions of the Korean Institute of Power Electronics
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• v.16 no.6
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• pp.610-617
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• 2011

This paper proposes a novel and direct dead-time compensation method of the 3-phase inverter using space vector pulse width modulation(SVPWM) topology. The proposed dead-time compensation method directly compensates the dead-time to the turn-on time of the effective voltage vector according to the current direction of the medium voltage reference. Each phase voltages are determined by the switching times of the effective voltage vectors, and the practical switching times have loss according to the current direction by the dead-time effect in the 3-phase inverter. The proposed method adds the dead-time to the switching time of the effective voltage vector according to the current direction, so it does not require complex d-q transform and controller to compensate the voltage error. The proposed dead-time compensation scheme is verified by the computer simulation and experiments of 3-phase R-L load.

• The Transactions of the Korean Institute of Power Electronics
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• v.12 no.4
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• pp.291-299
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• 2007

To operate a permanent magnet synchronous motor (PMSM) at a maximum torque per ampere (MTPA) operation point, the exact values of machine parameters such as inductances and back-EMF constant, which are sensitive to motor phase currents and temperature respectively, should be blown. An adaptive estimation method for on-line estimation of the machine parameters is not suitable for practical applications since it has difficulties in estimating exact values and requires complex mathematical calculations. The purpose of this paper is to present a simple MTPA operation point tracking control strategy for vector controlled PMSM drives with slow dynamic loads. The proposed method searches MTPA operation points by modulating current phase angle and observing the variation in command power. The current angle modulation strategy is designed to sense the effect of load variations in the command power. Therefore, the proposed method can track the MTPA operation points of the PMSM regardless of load variations. Computer simulation and experimental study is also presented to show the effectiveness of the proposed method.