• 정보처리학회논문지B
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• 제15B권4호
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• pp.323-330
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• 2008

복합질환은 다수의 유전자들이 상호작용하여 유발되는 질병으로서, 여러 유전자들이 관여한다는 복잡성 때문에 전통적인 분석 방법을 적용하는데 한계가 있다. 최근에는 기계학습 기법을 이용한 새로운 분석 방법들이 제안되고 있다. 신경망은 이처럼 복잡한 데이터에서 일정한 패턴을 찾아 이를 분류하는데 적합한 모델이다. 그러나 다량의 데이터가 입력으로 들어오는 경우에 학습에 오랜 시간이 걸리고 패턴을 찾기가 어려워지는 단점이 있다. 본 연구에서는 다량의 SNP 데이터로부터 질병에 연관된 소수의 중요 SNP을 찾기 위한 통계학적인 방법인 집합결합(set association)과 신경망을 결합한 모델을 제시한다. 이 모델을 천식 관련 SNP 데이터에 적용하여 천식 발병 여부를 예측한 결과, 신경망만 사용했을 때보다 실행 시간도 빠르고 예측 정확도도 높았다. 이 모델은 다른 복합질환의 예측에도 효과적으로 사용할 수 있을 것으로 기대한다.

• 식물분류학회지
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• 제50권1호
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• pp.8-16
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• 2020

Complete chloroplast genome sequences provide detailed information about any structural changes of the genome, instances of phylogenetic reconstruction, and molecular markers for fine-scale analyses. Recent developments of next-generation sequencing (NGS) tools have led to the rapid accumulation of genomic data, especially data pertaining to chloroplasts. Short reads deposited in public databases such as the Sequence Read Archive of the NCBI are open resources, and the corresponding chloroplast genomes are yet to be completed. The V. dilatatum complex in Korea consists of four morphologically similar species: V. dilatatum, V. erosum, V. japonicum, and V. wrightii. Previous molecular phylogenetic analyses based on several DNA regions did not resolve the relationship at the species level. In order to examine the level of variation of the chloroplast genome in the V. dilatatum complex, raw reads of V. dilatatum deposited in the NCBI database were used to reconstruct the whole chloroplast genome, with these results compared to the genomes of V. erosum, V. japonicum, and three other species in Viburnum. These comparative genomics results found no significant structural changes in Viburnum. The degree of interspecific variation among the species in the V. dilatatum complex is very low, suggesting that the species of the complex may have been differentiated recently. The species of the V. dilatatum complex share large unique deletions, providing evidence of close relationships among the species. A phylogenetic analysis of the entire genome of the Viburnum showed that V. dilatatum is a sister to one of two accessions of V. erosum, making V. erosum paraphyletic. Given that the overall degree of variation among the species in the V. dilatatum complex is low, the chloroplast genome may not provide a phylogenetic signal pertaining to relationships among the species.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2011년도 춘계학술발표대회 논문집
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• pp.141-146
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• 2011

The purpose of this study is to investigate the planning of the community spaces for sustainable apartment complex under the aging society. For this, it is needed to identify the practical meaning of community spaces for elderly residents. In many cases, existing apartments' community spaces have been designed without considering the elderly. In order to develop successful environment for aging society, it is necessary for us to precisely review how elderly residents are changing their needs. Survey and depth-interview methods were used for data collection of this study. This study was performed in the five subject apartments located in Haeundae new town, Busan. In planning of community spaces for sustainable apartment complex in the aging society, 1) The population of the elderly in apartment complex has been increased with progress of the aging society, and it has been necessary to enlarge and consider the aging-friendly community space. 2) When the community space is located in a good accessibility, visual openness, multipurpose composition and the center of complex, it was investigated that the degree of its usage was high. 3) Common apartment complex for the elderly was deficient, and the composition and the layout of community spaces were needed, which included sports facility, spaces for leisure culture and study. This study could be utilized as basic data for designing community spaces in apartments from the perspective of sustainable community.

• 한국도서관정보학회지
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• 제45권1호
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• pp.297-317
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• 2014

본 연구의 목적은 국가산업단지의 하나인 경기도 시흥시에 위치한 시흥스마트허브단지내 근로자의 삶의 질 향상과 기업경쟁력을 강화하기 위해 독서환경, 독서문화 실태 및 요구사항을 조사, 분석하여 독서문화 개선 및 활성화를 위한 기초자료를 삼고자 하였다. 산업체 근로자를 대상으로 설문을 하여 그 결과를 분석한 결과 산업단지 내 독서환경이 미비하였으며, 근로자의 독서문화 실태도 열악한 상황이었다. 이를 개선하기 위해 요구사항을 분석하여 산업체 근로자의 독서환경 개선과 독서문화 활성화를 위한 방안을 제시하였다.

• 가정과삶의질연구
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• 제22권6호
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• pp.89-97
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• 2004

The purpose of this study was to investigate the characteristics of leisure facilities and to examine residents' needs for leisure facilities in apartment complex. The questionnaire survey and content analysis were used. The Data for content analysis were 476 site plans, and the subjects of questionnaire survey were 673 residents lilving in 35 apartment complex. Frequency, Percentage, and mean, ANOVA-A, x^{2}-test, and multiple regression were used for data analysis. The major results were as follows. 1) Facilities for children play, and senior, sports facilities, community center, green area, and resting place were included in leisure facilities in apartment complex. These facilities were different according to complex site and built-period. 2)The degree of satisfaction of leisure facilities was lower than neutral. The satisfaction of leisure facilities related with diversity of leisure facilities and program, and poor environment. 3) Subjects needed the facilities recommended in housing act including diverse leisure facilities such as sports center and resident's self government facilities. And they needed divers facilities for sports. 4) In terms of location, they needed leisure facilities which was closer to their house.

• 한국측량학회지
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• 제38권5호
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• pp.455-465
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• 2020

As cities continue to expand and additional underground structures are constructed, a policy is being planned to expand addresses, which are national framework data. In this study, the application scope of a proposed 3D (three-dimensional) mixed-use complex space for assigning 3D addresses was defined, based on past research on 3D address systems and by analyzing related laws. Underpass shopping malls, underground walkways (excluding underground shopping malls), and 3D mixed-use transfer centers with a gross floor area of 2,000㎡ or more are connected with each space by underground walkways or public paths. In addition, the detailed space corresponding to the public space of the 3D mixed-use complex space was presented and distinguished from the space to which the detailed address is assigned. The criteria for setting the road section were presented based on the intermediate space, which is a characteristic of 3D mixed-use complex spaces. The proposed criteria were applied to the Express Bus Terminal station (3D mixed-use transfer center) and COEX mall (underpass shopping malls). Thus, the road section was set for an unfamiliar 3D mixed-use complex space. However, by applying the proposed criteria to various 3D mixed-use complex spaces, additional and detailed criteria for different cases should be prepared.

• Journal of Nutrition and Health
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• 제45권6호
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• pp.600-612
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• 2012

Nutritional researchers world-wide are using large-scale sample survey methods to study nutritional health epidemiology and services utilization in general, non-clinical populations. This article provides a review of important statistical methods and software that apply to descriptive and multivariate analysis of data collected in sample surveys, such as national health and nutrition examination survey. A comparative data analysis of the Korea National Health and Nutrition Examination Survey (KNHANES) was used to illustrate analytical procedures and design effects for survey estimates of population statistics, model parameters, and test statistics. This article focused on the following points, method of approach to analyze of the sample survey data, right software tools available to perform these analyses, and correct survey analysis methods important to interpretation of survey data. It addresses the question of approaches to analysis of complex sample survey data. The latest developments in software tools for analysis of complex sample survey data are covered, and empirical examples are presented that illustrate the impact of survey sample design effects on the parameter estimates, test statistics, and significance probabilities (p values) for univariate and multivariate analyses.

• Communications for Statistical Applications and Methods
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• 제9권3호
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• pp.853-864
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• 2002

In the analysis of categorical data subject to misclassification errors, the observed cell proportions are adjusted by a misclassification probabilities and estimates of variances are adjusted accordingly. In this case, it is important to determine the extent to which misclassification probabilities are homogeneous within a population. This paper considers methods to evaluate the power of chi-squared tests for homogeneity with complex survey data subject to misclassification errors. Two cases are considered: adjustment with homogeneous misclassification probabilities; adjustment with heterogeneous misclassification probabilities. To estimate misclassification probabilities, logistic regression method is considered.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2004년도 추계학술대회 논문집
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• pp.163-168
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• 2004

The purpose of this study is to analyse the climatic characteristic of South Korea and use it as a fundamental data for planning an environmental housing complex in Seoul, the capital of South Korea. The world after the Industrial Revolution has greatly developed economically but falied to notice the importance of the environment. It has been gradually damaged by the reckless exploitation for tens of years, and thus inflicted a loss on human. In this study, necessity and usability of the application of the climatic element for planning the environmental housing complex are to be presented. The data used in this study are given by the Met.

• Asian Journal of Atmospheric Environment
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• 제5권1호
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• pp.1-7
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• 2011

This study assesses the dispersion and emission rates of odor form industrial area source. CALPUFF and AERMOD Gaussian models were used for predicting downwind odor concentration and calculating odor emission rates. The studied region was Seobu industrial complex in Korea. Odor samples were collected five days over a year period in 2006. In-site meteorological data (wind direction and wind speed) were used to predict concentration. The BOOT statistical examination software was used to analyze the data. Comparison between the predicted and field sampled downwind concentration using BOOT analysis indicates that the CALPUFF model prediction is a little better than AERMOD prediction for average downwind odor concentrations. Predicted concentrations of AERMOD model have a little larger scatter than that of CALPUFF model. The results also show odor emission rates of Seobu industrial complex area were an order of 10 smaller than that of beef cattle feed lots.