• Journal of Korean Neurosurgical Society
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• v.63 no.2
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• pp.237-247
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• 2020

Objective : Fixation of the C1-2 segment is challenging because of the complex anatomy in the region and the need for a high degree of accuracy to avoid complications. Preoperative 3D-computed tomography (CT) scans can help reduce the risk of complications in the vertebral artery, spinal cord, and nerve roots. However, the patient may be susceptible to injury if the patient's anatomy does not match the preoperative CT scans. The intraoperative 3D image-based navigation systems have reduced complications in instrument-assisted techniques due to greater accuracy. This study aimed to compare the radiologic outcomes of C1-2 fusion surgery between intraoperative CT image-guided operation and fluoroscopy-guided operation. Methods : We retrospectively reviewed the radiologic images of 34 patients who underwent C1-2 fusion spine surgery from January 2009 to November 2018 at our hospital. We assessed 17 cases each of degenerative cervical disease and trauma in a study population of 18 males and 16 females. The mean age was 54.8 years. A total of 139 screws were used and the surgical procedures included 68 screws in the C1 lateral mass, 58 screws in C2 pedicle, nine screws in C2 lamina and C2 pars screws, four lateral mass screws in sub-axial level. Of the 34 patients, 19 patients underwent screw insertion using intraoperative mobile CT. Other patients underwent atlantoaxial fusion with a standard fluoroscopy-guided device. Results : A total of 139 screws were correctly positioned. We analyzed the positions of 135 screws except for the four screws that performed the lateral mass screws in C3 vertebra. Minor screw penetration was observed in seven cases (5.2%), and major pedicle screw penetration was observed in three cases (2.2%). In one case, the malposition of a C2 pedicle screw was confirmed, which was subsequently corrected. There were no complications regarding vertebral artery injury or onset of new neurologic deficits. The screw malposition rate was lower (5.3%) in patients who underwent intraoperative CT-based navigation than that for fluoroscopy-guided cases (10.2%). And we confirmed that the operation time can be significantly reduced by surgery using intraoperative O-arm device. Conclusion : Spinal navigation using intraoperative cone-beam CT scans is reliable for posterior fixation in unstable C1-2 pathologies and can be reduced the operative time.

• Progress in Medical Physics
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• v.19 no.3
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• pp.178-185
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• 2008

Living donor liver transplantation is increasingly performed as an alternative to cadaveric transplantation. Preoperative screening of the donor candidates is very important. The quality, size, and vascular and biliary anatomy of the liver are best assessed with magnetic resonance (MR) imaging or computed tomography (CT). In particular, the volume of the potential graft must be measured to ensure sufficient liver function after surgery. Preoperative liver segmentation has proved useful for measuring the graft volume before living donor liver transplantations in previous studies. In these studies, the liver segments were manually delineated on each image section. The delineated areas were multiplied by the section thickness to obtain volumes and summed to obtain the total volume of the liver segments. This process is tedious and time consuming. To compensate for this problem, automatic segmentation techniques have been proposed with multiplanar CT images. These methods involve the use of sequences of thresholding, morphologic operations (ie, mathematic operations, such as image dilation, erosion, opening, and closing, that are based on shape), and 3D region growing methods. These techniques are complex but require a few computation times. We made a phantom for volume measurement with pig and evaluated actual volume of spleen and liver of phantom. The results represent that our semiautomatic volume measurement algorithm shows a good accuracy and repeatability with actual volume of phantom and possibility for clinical use to assist physician as a measuring tool.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.44.1-44.1
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• 2016

The Sagittarius-Carina spiral arm in the Galaxy contains several massive young open clusters. We present a deep optical photometric study on the massive young open clusters in the Sagittarius-Carina arm, Westerlund 2 and the young open clusters in the ${\eta}$ Carina nebula. Westerlund 2 is a less studied starburst-type cluster in the Galaxy. An abnormal reddening law for the intracluster medium of the young starburst-type cluster Westerlund 2 is determined to be $R_{V,cl}=4.14{\pm}0.08$. The distance modulus is determined from zero-age main-sequence fitting to the reddening-corrected color-magnitude diagrams of the early-type members to be $V_0-M_V=13.9{\pm}0.14mag$. The pre-main sequence (PMS) members of Westerlund 2 are selected by identifying the optical counterparts of X-ray emission sources from the Chandra X-ray observation and mid-infrared emission sources from the Spitzer/IRAC (the Infrared Array Camera) observation. The initial mass function (IMF) shows a slightly flat slope of ${\Gamma}=-1.1{\pm}0.1$ down to $5M_{\odot}$. The age of Westerlund 2 is estimated to be. 1.5 Myr from the main-sequence turn-on luminosity and the age distribution of PMS stars. The ${\eta}$ Carina nebula is the best laboratory for the investigation of the Galactic massive stars and low-mass star formation under the influence of numerous massive stars. We have performed deep wide-field CCD photometry of stars in the ${\eta}$ Carina nebula to determine the reddening law, distance, and the IMF of the clusters in the nebula. We present VRI and $H{\alpha}$ photometry of 130,571 stars from the images obtained with the 4m telescope at Cerro Tololo Inter-American Observatory (CTIO). RV,cl in the η Carina nebula gradually decreases from the southern part (~4.5, around Trumpler 14 and Trumpler 16) to the northern part around Trumpler 15 (~3.5). Distance to the young open clusters in the ${\eta}$ Carina nebula is partly revised based on the zero-age main-sequence fitting to the reddening-corrected color-magnitude diagrams (CMDs) and the (semi-) reddening-independent CMDs. We select the PMS members and candidates by identifying the optical counterparts of X-ray sources from the Chandra Carina Complex Survey and mid-infrared excess emission stars from the Spitzer Vela-Carina survey. From the evolutionary stage of massive stars and PMS stars, we obtain that the northern young open cluster Trumpler 15 is distinctively older than the southern young open clusters, Trumpler 14 (${\leq}2.5 Myr$) and Trumpler 16 (2.5-3.5 Myr). The slopes of the IMF of Trumpler 14, Trumpler 15, and Trumpler 16 are determined to be $-1.2{\pm}0.1$, $-1.5{\pm}0.3$, and $-1.1{\pm}0.1$, respectively. Based on the RV,cl of several young open clusters determined in this work and the previous studies of our group, We suggest that higher RV,cl values are commonly found for very young open clusters with the age of < 4 Myr. We also confirm the correlation between the slope of the IMF and the surface mass density of massive stars.

• Journal of KIBIM
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• v.2 no.2
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• pp.1-9
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• 2012

In Korea, recently, efforts have been made to introduce BIM(Building Information Modeling) to housing complex projects. However, there have been several problems including excessive competition for building design and outcome-oriented evaluation due to a lack of clear evaluation criteria and poorly organized management process. Under this circumstance, the study surveyed opinions of project managers and conducted a pilot test to improve evaluation criteria of BIM-based design for housing complexes. The objective is to assess the level of BIM technology and its applicability, and to propose a list of reasonable evaluation criteria for better project management. First, the study examined the current condition of evaluation on the BIM-based housing complexes, and identified 15 preliminary items that might be suitable for application of BIM. Second, the study conducted a pilot test for the 15 items to determine their suitability for the level of BIM technology, clarity of the calculation process, and the extent of fulfilling information quality, and short-listed eight items for application of BIM. In particular, in the design concept stage, mostly 3D visual images and area-related items are suitable for BIM-based evaluation. Accordingly, formerly used items such as project cost, energy and environmental analysis, building structure, and facilities were deemed more relevant to the subsequent stages of basic design and its implementation.

• Journal of the Korean Institute of Landscape Architecture
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• v.36 no.2
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• pp.69-79
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• 2008

Landscape indices are effective tools to explain the spatial structure and patterns of ecological landscape including area/density, shape, core area, isolation/proximity, contagion/interspersion, and connectivity. More than 100 indices have been developed and an increasing amount of research explains changes in urban spaces using the indices. However, landscape indices have a high level of sensitivity to the scale of analysis - grain size and extent. If the scale sensitivity of indices is not considered, the research may produce inaccurate results. This study examines the scale sensitivity of landscape indices to find relatively stable indices in the complex geographical features of Korea. The scale sensitivity was analyzed using 20 categories of grain size and 41 categories of extent change. Landsat TM and ETM+ images of five years - 1985, 1991, 1996, 2000 and 2003 - were used, and 54 class level indices mounted on the FRAGSTATS program were examined. The results are as follows: First, according to the analysis of the scale sensitivity, 19 out of 54 class level indices were found to be stable to scale change. Second, the scale sensitivity was closely related to the green area ratio, and the typical threshold of change was $40{\sim}50%$. Third, among the 16 indices which were frequently used in the research in Korea, only 6 indices were relatively stable to the scale change. These results can be an effective basis for the selection of indices in the landscape ecology research in Korea.

• Journal of the Economic Geographical Society of Korea
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• v.1 no.2
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• pp.85-102
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• 1998

The Changing Characteristics of Office Location in Central Seoul In recent years, central Seoul has been experiencing a dynamic transformation. In the process of reorganization of urban industrial structure including tertiarization and quaternarization of the economic base of Seoul, business services are growing very rapidly and large scale urban renewal projects are agilely implemented. Downtown office activities become a nucleus for economic performance of Seoul and high-rise office buildings steer the landscape transformation of central Seoul. Even though there appear to exist some evidences that office districts have dispersed to several subcenters, major office activities are still concentrated in the central Seoul. This paper redefines office industry in a narrow meaning comprising only relevant economic sectors and office buildings as office activity-functioning units. It then explores the industrial networking and territorial specialization of office activities focusing on the dual process of concentration and dispersion in Seoul. The changing characteristics of the downtown linkages of office activities in this post-industrial era transforms the spatial economy of central Seoul into more flexible and volatile, while territorial concentration of power and control functions are fortified at the same time. Finally, the paper addresses the development of manufacturing-tertiary-quaternary industrial complex, which can be regarded as new industrial clusters, selling cultural economy of urban space and possessing placeness or images for clients and customers, in relation to urban competitiveness and territorial specialization of large metropolitan areas.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.461-472
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• 2004

Objectives : For the screening of neuroprotective effects of medicinal herbs, the complex system of animal models suffer some disadvantages in controlling critical parameters such as blood pressure and body temperature. Additionally, application of drugs to the appropriate brain area sometimes is difficult, due to poor permeability though the blood brain barrier, and so potential protective effects might be masked. Methods : Organotypic hippocampal slice culture (OHSC) method has the advantages of being relatively easy to prepare and of maintaining the general structure, including tissue integrity and the connections between cells. Drugs can easily be applied and neuronal damage can easily be quantified by using tissues and culture media. This study demonstrates neuroprotective effects of Puerariae radix (葛根, PR), Salviae miltiorrhizae radix (丹蔘, SR), Rhei rhizoma (大黃, RR), and Bupleuri radix (柴胡, BR). These were screenedand compared to MK-801, antagonist of NMDA receptors, by using OHSC of 1 week-old Sprague-Dawley rats. Oxygen/glucose deprivation (OGD) were conducted in an anaerobic chamber $(85%\;N_2,\;10%\;CO_2\;and\;5%\;H_2)$ in a deoxygenated glucose-free medium for 60 minutes. Water extracts of each herbs were treated to culture media with $5\;{\mu}g/ml$ for 48 hours. Results : Neuronal cell death in the cultures was monitored by densitometric measurements of the cellular uptake of propidium iodide (PI). PI fluorescence images were obtained at 48 hours after the OGD and medicinal herb treatment. Also TUNEL-positive cells in the CAI and DG regions and LDH concentrations in culture media were measured at 48 hours after the OGD. According to measured data, MK-801, PR, SR and BR demonstrated significant neuroprotective effect against excessive neuronal cell death and apoptosis induced by the OGD insult. Especially, PR revealed similar neuroprotective effect to MK-801 and RR demonstrated weak neuroprotective effect. Conclusions : These results suggest that OHSC can be a suitable method for screening of neuroprotective effects of medicinal herbs. (This work was supported by the research program of Dongguk University and Grant 01-PJ9-PG1-01CO03-0003 from Ministry of Health & Welfare.)

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.12
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• pp.168-175
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• 2013

Color consistency in stereoscopic contents is important for 3D display systems. Even with a stereo camera of the same model and with the same hardware settings, complex color discrepancies occur when acquiring high quality stereo images. In this paper, we propose an integrated color matching method that use cumulative histogram in global matching and estimated 3D-distance for the stage of local matching. The distance between the current pixel and the target local region is computed using depth information and the spatial distance in the 2D image plane. The 3D-distance is then used to determine the similarity between the current pixel and the target local region. The overall algorithm is described as follow; First, the cumulative histogram matching is introduced for reducing global color discrepancies. Then, the proposed local color matching is established for reducing local discrepancies. Finally, a weight-based combination of global and local matching is computed. Experimental results show the proposed algorithm has improved global and local error correction performance for stereoscopic contents with respect to other approaches.

• Economic and Environmental Geology
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• v.29 no.5
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• pp.545-559
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• 1996

Rare metal (Nb-Zr-REE) ore deposits are located in the Chungju area. Geotectonically, the rare metal ore deposits are situated in the transitional zone between Kyeonggi massif and Okcheon belt. The rare metal deposits are distributed in Kyemyeongsan Formation which consist of schist and alkaline igneous rocks. Alkali granite has suffered extensive post-magmatic metasomatism and hydrothermal processes. The ore contains mainly Ce-La, Ta-Nb, Y, Y-Nd, Nd-Th group minerals. More than 15 RE and REE minerals are found in the ore deposits. Allanite, one of the Ce-La rich REE minerals belonging to the epidote group, is the most common mineral in the studied area. The allanite- bearing rocks may be devided into seven types by features of occurrence and mineral associations; zircon type (ZT), allanite-vein type (AT), feldspar type (KT), fluorite type (FT), quartz-mica type (QT), iron-oxide type (MT), and amphibole type (HT). The allanite veins (AT) and zircon rich rocks (ZT) contain the highest total REE contents. Differences in REE abundance can be interpreted in terms of varying portions of magmatic hydrothermal fluid. Petrographical and chemical data are presented for allanites which were collected from different types. The allanites show wide variations in optical properties, due in part to differences in their chemical composition (depending on the types) and to the degree of crystallinity of the individual specimens. Allanite metamicts in biotite are generally surrounded by well developed pleochroic haloes. Usually, allanite is accompanied by zircon and other REE-bearing minerals. CaO and total REE contents $({\sum}RE_2O_3)$ range from 9.29 to 18.79% and 11.66 to 26.31%, respectively. Also, SiO, (28.87~32.61%), $Al_2O_3$ (8.30~16.88%), and $Fc_2O_3$ (16.74~24.38%) contents show varying contents from type to type. The ${\sum}RE_2O_3$ of allanite has positive relationships with $Fe_2O_3$ and negative relaton with CaO, $SiO_2$, and $Al_2O_3$ Backscattered electron microscope images (BEl) of allanite shows that the its mineral composition and texture is very complex. The allanite-bearing hosts show distinct light REE enrichment with strong negative Eu anomaly except for HI. The HT has an almost flat REE distribution pattern with a small negative Eu anomaly. The chemical variation of the allanites with occurrences and mineral association can be related to condition of temperature and oxidation states in precipitation environment.

• Journal of the Korean Society for Nondestructive Testing
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• v.33 no.2
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• pp.129-137
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• 2013

A force calibration of a nanoindenter and a 3D morphology observation of indenters were carried out in this study. A microbalance calibrated with standard weights was used for measuring the loads generated by a nanoindenter. The indentation load could be calibrated from the ratio of measured and generated loads and the first contact load also could be detected from the microbalance data. By analyzing atomic force microscopy images of two indenters, curvature radii of apexes were determined by $19.71{\pm}3.03$ and $1043.94{\pm}50.91$ nm, respectively, for the nearly new indenter A and the severly worn indenter B. Corresponding bluntness depths were estimated by 1.22 and 64.56 nm for the both indenters by overlapping their profiles on the perfect pyramidal shape. In addition, nanoindentation curves obtained from a fused silica reference material with the both indenters showed a depth difference corresponding to the bluntness depth difference along the indentation depth axis. By shifting amounts of the bluntness depths along the horizontal axis, whole nanoindentation curves overlapped on themselves and resulted in nanohardness values consistent within 1.11 % without considering the complex indenter area function of each indenter.