• Journal of Ginseng Research
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• 제45권5호
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• pp.546-554
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• 2021

Background: Diabetes mellitus and hypertension often occur together, amplifying cardiovascular disease (CVD) risk and emphasizing the need for a multitargeted treatment approach. American ginseng (AG) and Korean Red Ginseng (KRG) species could improve glycemic control via complementary mechanisms. Additionally, a KRG-inherent component, ginsenoside Rg3, may moderate blood pressure (BP). Our objective was to investigate the therapeutic potential of coadministration of Rg3-enriched Korean Red Ginseng (Rg3-KRG) and AG, added to standard of care therapy, in the management of hypertension and cardiometabolic risk factors in type-2 diabetes. Methods: Within a randomized controlled, parallel design of 80 participants with type-2 diabetes (HbA1c: 6.5-8%) and hypertension (systolic BP: 140-160 mmHg or treated), supplementation with either 2.25 g/day of combined Rg3-KRG + AG or wheat-bran control was assessed over a 12-wk intervention period. The primary endpoint was ambulatory 24-h systolic BP. Additional endpoints included further hemodynamic assessment, glycemic control, plasma lipids and safety monitoring. Results: Combined ginseng intervention generated a mean ± SE decrease in primary endpoint of 24-h systolic BP (-3.98 ± 2.0 mmHg, p = 0.04). Additionally, there was a greater reduction in HbA1c (-0.35 ± 0.1% [-3.8 ± 1.1 mmol/mol], p = 0.02), and change in blood lipids: total cholesterol (-0.50 ± 0.2 mmol/l, p = 0.01), non-HDL-C (-0.54 ± 0.2 mmol/l, p = 0.01), triglycerides (-0.40 ± 0.2 mmol/l, p = 0.02) and LDL-C (-0.35 ± 0.2 mmol/l, p = 0.06) at 12 wks, relative to control. No adverse safety outcomes were observed. Conclusion: Coadministration of Rg3-KRG + AG is an effective addon for improving BP along with attaining favorable cardiometabolic outcomes in individuals with type 2 diabetes. Ginseng derivatives may offer clinical utility when included in the polypharmacy and lifestyle treatment of diabetes. Clinical trial registration: Clinicaltrials.gov identifier, NCT01578837;

• 한국산학기술학회논문지
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• 제20권7호
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• pp.291-298
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• 2019

논문에서는 국내에서 운용되는 수중유도무기(어뢰) 중 추진전지(리튬이차전지)의 전해질 누액에 의한 발연현상을 방지하기 위하여 추진전지의 절연블록 추가를 통한 절연성능 강화 및 단전지 전해액 누액 방지 개선방법에 관해 기술하였다. 국내에서 리튬이차전지를 주전원공급원(추진전지)으로 사용하고 있는 어뢰에 발열 및 발연 현상이 발생하여 해군의 장비 운용에 불편함이 초래되었다. 발연현상에 대한 유의 항목 확인 및 모사시험 결과 전지팩 단위에서 일부 전지셀의 전해질이 누액되어 고전압부분의 주전원 회로와 단자탭간에 단락현상이 발생하여 해당 현상이 발생하였다. 발열 및 발연현상 시 리튬이차전지 특성 및 메커니즘 분석을 통하여 원인분석을 진행하였다. 리튬 이차전지의 전해질 누액 방지를 위해 근본적 개선책(단자 탭 강화)과 보완책(절연블록 선정 및 설치) 등 설계 개선을 수행하였고, 개선 전 후의 성능시험 비교 결과 탭 단자의 인장강도가 약 2배 향상, 내압 특성 또한 향상되었으며, 절연성능 강화로 어뢰의 추진전지 품질을 대폭 개선하였다. 또한 품질개선 방안이 적용되어 3년 이상 야전 운용 결과 이상발연 현상은 발생하지 않았다. 이로써 어뢰 추진전지의 운용 및 저장 안정성 기대된다.

• 한국구조물진단유지관리공학회 논문집
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• 제25권3호
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• pp.48-56
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• 2021

최근 세계적으로 발생한 지진으로 구조물의 내진보강에 대한 관심이 높아지고 있다. 구조물의 내진성능 향상을 위하여 기둥에 대한 내진 보강이 이루어져야 한다. 기둥의 내진성능을 개선하기 위하여 다양한 보강법이 개발되고 있다. 본 연구에서는 RC기둥의 내진성능을 향상시키기 위하여, 기둥의 표면에 구속응력을 가력하여 내진성능을 평가하기 위한 해석적 연구를 수행하였다. 해석적 연구를 위하여 기둥에 대한 실험연구를 활용하였으며, 실험결과와 해석결과의 파괴형상 및 거동특성을 비교하였다. 해석결과 표면구속응력의 강도에 따라 RC기둥의 연성거동이 발생하였다. 일정 표면구속강도 이상에서는 연성거동이 거의 일정하게 발생하였다. 실험결과와 비교하여 실험에서 사용된 보강재의 보강정도를 RC기둥에 대한 표면구속응력값과 비교하여, 보강효과를 표면구속응력으로 검토하였다. 결론적으로, 본 연구에서 RC기둥의 연성거동을 위한 표면구속응력과 구속강도를 도출하였다. 도출한 결과를 바탕으로 RC기둥의 연성거동유도를 이용한 내진 설계 방법 및 내진성능 보가효과의 검토에 대한 기초자료로 활용이 가능할 것으로 판단된다.

• Animal Bioscience
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• 제35권2호
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• pp.184-195
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• 2022

Objective: In this study we aimed to evaluate the effect of dietary live yeast supplementation on ruminal pH pattern, fermentation characteristics and associated bacteria in beef cattle. Methods: This work comprised of in vitro and in vivo experiments. In vitro fermentation was conducted by incubating 0%, 0.05%, 0.075%, 0.1%, 0.125%, and 0.15% active dried yeast (Saccharomyces cerevisiae, ADY) with total mixed ration substrate to determine its dose effect. According to in vitro results, 0.1% ADY inclusion level was assigned in in vivo study for continuously monitoring ruminal fermentation characteristics and microbes. Six ruminally cannulated steers were randomly assigned to 2 treatments (Control and ADY supplementation) as two-period crossover design (30-day). Blood samples were harvested before-feeding and rumen fluid was sampled at 0, 3, 6, 9, and 12 h post-feeding on 30 d. Results: After 24 h in vitro fermentation, pH and gas production were increased at 0.1% ADY where ammonia nitrogen and microbial crude protein also displayed lowest and peak values, respectively. Acetate, butyrate and total volatile fatty acids concentrations heightened with increasing ADY doses and plateaued at high levels, while acetate to propionate ratio was decreased accordingly. In in vivo study, ruminal pH was increased with ADY supplementation that also elevated acetate and propionate. Conversely, ADY reduced lactate level by dampening Streptococcus bovis and inducing greater Selenomonas ruminantium and Megasphaera elsdenii populations involved in lactate utilization. The serum urea nitrogen decreased, whereas glucose, albumin and total protein concentrations were increased with ADY supplementation. Conclusion: The results demonstrated dietary ADY improved ruminal fermentation dose-dependently. The ruminal lactate reduction through modification of lactate metabolic bacteria could be an important reason for rumen pH stabilization induced by ADY. ADY supplementation offered a complementary probiotics strategy in improving gluconeogenesis and nitrogen metabolism of beef cattle, potentially resulted from optimized rumen pH and fermentation.

• 한국지반공학회논문집
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• 제23권7호
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• pp.5-16
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• 2007

수중 산사태의 관측 및 조사는 산사태의 메커니즘의 이해, 설계 및 시공의 유용성, 그리고 손실 감소에 도움을 준다. 본 논문은 실험실 조건의 수중 산사태를 확인하기 위하여 전기저항, 초음파 반사 이미지, 그리고 전단파 토모그래피의 3가지 고해상도 지구물리탐사기법을 수행하였다. 전기저항 탐침에 의한 흙의 전기저항 프로파일은 밀리미터 단위의 해상도로 흙의 공간적 분포 평가를 위한 자세한 정보를 제공해 준다. 임피던스가 다른 물질의 경계면부터의 반사 자료에 의한 초음파 반사 이미지는 밀리미터 단위의 해상도로 사면 형상 및 시료 층상을 탐지해 낼 수 있다. 전단파 이동 시간으로부터 얻어지는 경계 정보의 역산에 의한 픽셀단위 수중 산사태의 이미지를 만들 수 있다. 실험결과 초음파 이미지와 전기저항은 서로 보완적인 정보를 제공할 수 있으며, 전단파 토모그래피 이미지와 연합하여 수중 산사태의 3차원 이미지를 얻을 수 있다. 본 연구는 지구물리탐사기법들이 수중 산사태 및 해안의 공간적 분포의 탐지에 효과적인 기법이 될 수 있음을 보여준다.

• 대한토목학회논문집
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• 제26권1C호
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• pp.63-72
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• 2006

도심지의 급속한 성장으로 인한, 사회 기간시설 확충 필요성으로 현재 많은 터널이 시공되고 있으며 앞으로 더 많은 터널 공사가 계획되고 있다. 도심지에서의 터널 굴착은 일반적으로 터널 심도가 얕고 지상에 각종 건물, 공공시설이 밀집 되어 있어 터널굴착에 따른 지반 침하로 지상 구조물 및 지중 매설관에 피해를 주는 경우가 빈번히 발생하고 있어 주변지반의 거동, 구조물의 영향 검토의 중요성이 대두되고 있고, 민원 발생이 우려되는 도심지의 특수성 때문에 도심지 터널설계/시공은 산악터널과 다른 맥락에서 접근되어야 한다. 본 논문에서는 도심지 광역 단위 터널 현장의 최소 단면을 해석 후 전단면에 대한 예측이 가능할 경우 터널 시공위험도 평가에 효율적이기에 그 방법으로 전문가 시스템 인공신경망(Artificial Neural Network, ANN)기법을 적용하여 터널 안정성 검토방안을 연구하였다. 또한 그 결과를 GIS에 연계하여 터널 시공중 실시간(real time)개념으로 지반거동 및 주변 환경에 미치는 영향 평가를 수행하여 시공에 반영하는 정보화 개념의 시공관리기법을 강구하였다.

• 대한토목학회논문집
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• 제30권6D호
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• pp.587-597
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• 2010

교통사고가 발생하면 사고 당사자들은 민 형사적인 문제에서 자유롭지 못하기 때문에, 교통사고 조사자는 사고 상황을 정확하게 재현 또는 분석을 하여야 한다. 또한, 이러한 교통사고 발생과 관련한 요인에 대한 분석을 통해 얻어진 자료를 활용하여 교통사고 다발지역의 개선 및 보완작업을 시행하게 된다. 현재까지 알려진 바로는 수많은 교통사고, 교통시설물, 도로설계 등과 관련하여 가장 많은 영향을 미치는 요인은 차량의 속도와 가속능력, 제동능력 등이다. 이는 자동차의 성능과 노면의 마찰계수가 가장 밀접한 영향을 미치는 부분이다. 특히, 사고 순간의 속도의 추정은 교통사고처리특례법의 11개 주요항목인 과속과 관련하여 매우 중요한 사항이기에 정확성이 요구되는 부분이다. 하지만, 국내에서는 아직 이러한 부분에 대한 심도 있는 연구가 많이 진행되지 못하는 것이 현실이다. 이러한 현실을 반영하여 본 연구에서는 차량의 급제동에서 제동흔적이 발생되기 시작할 때까지의 시간인 제동경과시간을 정밀가속도계(Vericom VC2000PC)로 측정하여 제동경과시간과 노면의 마찰계수를 정확히 추정하였다. 실험결과를 분석하여, 여러 가지 특수 아스팔트 포장 및 미끄럼방지포장 종류에 따른 제동경과시간과 마찰계수를 계산하여 연구의 목적에 맞도록 기초자료를 제공하고자 하였다.

• 한국정보기술학회 영문논문지
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• 제9권1호
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• pp.115-125
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• 2019

In this paper, the image is received from the camera and the lane is sensed. There are various ways to detect lanes. Generally, the method of detecting edges uses a lot of the Sobel edge detection and the Canny edge detection. The minimum use of multiplication and division is used when designing for the hardware configuration. The images are tested using a black box image mounted on the vehicle. Because the top of the image of the used the black box is mostly background, the calculation process is excluded. Also, to speed up, YCbCr is calculated from the image and only the data for the desired color, white and yellow lane, is obtained to detect the lane. The median filter is used to remove noise from images. Intermediate filters excel at noise rejection, but they generally take a long time to compare all values. In this paper, by using addition, the time can be shortened by obtaining and using the result value of the median filter. In case of the Sobel edge detection, the speed is faster and noise sensitive compared to the Canny edge detection. These shortcomings are constructed using complementary algorithms. It also organizes and processes data into parallel processing pipelines. To reduce the size of memory, the system does not use memory to store all data at each step, but stores it using four line buffers. Three line buffers perform mask operations, and one line buffer stores new data at the same time as the operation. Through this work, memory can use six times faster the processing speed and about 33% greater quantity than other methods presented in this paper. The target operating frequency is designed so that the system operates at 50MHz. It is possible to use 2157fps for the images of 640by360 size based on the target operating frequency, 540fps for the HD images and 240fps for the Full HD images, which can be used for most images with 30fps as well as 60fps for the images with 60fps. The maximum operating frequency can be used for larger amounts of the frame processing.

• Journal of Korea Trade
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• 제27권5호
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• pp.113-136
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• 2023

Purpose - Global production chains and their impacts on economic growth have drawn extensive attention from researchers. Close relationships among global production chains, export and economic growth have been illuminated, as evidenced by the fast and stable economic growth of East Asian economies. These economies perform various roles within global production chains using offshoring, in which the impact of import on domestic gross output is as strong as that of export. The impact of import on economic growth would depend on whether imported inputs substitute or complement domestic inputs production, which is likely to vary according to individual countries' functions within global production chains. The economic growth of concerned countries would also be diverse. However, little attention has been paid to the impact brought by imports compared to its significance. Design/methodology - The principal methodology used in this paper is structural decomposition analysis (SDA), widely chosen to elucidate the impact of various factors on domestic gross output using input-output tables. This paper extracts trade data of six Asian economies from the World Input-Output Database (WIOD) 2016 release that covers 43 countries for the period 2000-2014. The extracted data is then categorised into 37 sectors. First, this paper calculates the Feenstra-Hanson Offshoring Index (OSI) of each country. It then applies SDA to measure the changes in each economy's gross output, export, import input coefficients, and domestic input coefficients. Finally, after taking the first difference from pooled time-series data, it estimates the correlations between imported input coefficients and OSI using the ordinary least square (OLS) method. Findings - The main findings of this paper can be summarised as follows. Firstly, all six countries have increasingly engaged in global production chains, as evidenced by the growing size of OSI. Secondly, there are negative correlations in five countries except Japan, with sectoral differences. Thirdly, changes in import input coefficients are not negative in all six countries, indicating that offshoring does not necessarily substitute for domestic inputs production but does complement it and, therefore, fosters their economic growth. This is observed in China, Indonesia, Korea and Taiwan. Offshoring has led to an increase in the use of imported inputs, which has, in turn, stimulated domestic inputs production in these countries. Originality/value - While existing studies focus on the role of export in evaluating the impact of participating global production chains, this paper explicitly examines the unexplored impact of import on domestic gross output by considering both the substitution and the complementary effect, using the WIOD. The findings of this paper suggest that Asian economies have achieved fast and stable economic growth not only through successful export management but also through effective import management within global production chains. This paper recommends that the Korean government and enterprises carefully choose offshoring strategies to minimise disruption to domestic production chains or foster them.

• Journal of Korea Trade
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• 제27권5호
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• pp.1-22
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• 2023

Purpose - Southeast Asia has been the focus of Korea's foreign investment. Korea has been helping developing countries in Southeast Asia achieve economic growth and win-win cooperation through capital exports. FDI is an important channel for technology diffusion. However, the impact of FDI on the bias of technological progress in the host country is dependent on the host country's own endowment structure and capital-labor factor substitution elasticity. Therefore, the central issue of this paper is to accurately evaluate the impact of Korea's FDI to the four Southeast Asian countries in various industries on their bias of technological progress. Design/methodology - The paper uses macroeconomic data for Korea and four East Asian countries to estimate capital-labor factor elasticities of substitution using nonlinear, seemingly uncorrelated regressions (NLSUR). Then, the biased technological change index (BTCI) is calculated for each country. Finally, panel data analysis is used to explore the impact of Korean FDI in various industries in the four Southeast Asian countries on their own directed technological progress, and a robustness test is conducted. Findings - There is a substitution relationship between capital and labor factors based on their elasticity in Korea, Singapore and the Philippines. There is a complementary relationship between capital and labor factors in Indonesia and Malaysia. According to the BTCI, there is a trend toward labor-biased technological progress in all countries. Korean investments in manufacturing, wholesale and retail trade in the host country trigger capital-biased technological change in the host country; investments in the finance, insurance and information and communication sectors trigger labor-biased technological change. In addition, this paper also confirms that directed technological progress can enable cross-country transmission. Originality/value - The innovation of this paper lies in three aspects. First, we estimate the BTCI for five countries and explore the trend and situation of directed technological progress in each country from each country's own perspective. Second, we explore the impact of Korean FDI in the host country on the bias to its technological progress at the industry level. Second, we explore the impact of Korean FDI in various industries in the four Southeast Asian countries on the four countries' own directed technological progress from a national perspective. Finally, we propose corresponding countermeasures for technological progress from the perspective of inverse factor endowment. These innovative points not only expand the understanding of technological progress and cross-country technology transfer in East Asia but also provide practical references for policy-makers and business operators.