• 제목/요약/키워드: Comparative Mapping

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작물 육종에서 분자유전자 지도의 이용 (Genome Mapping Technology And Its Application In Plant Breeding)

  • 은무영
    • 한국식물학회:학술대회논문집
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    • 한국식물학회 1995년도 제9회 식물생명공학 심포지움 식물육종과 분자생물학의 만남 The 9th Plant Biotechnology Symposium -Breeding and Molecular Biology-
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    • pp.57-86
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    • 1995
  • Molecular mapping of plant genomes has progressed rapidly since Bostein et al.(1980) introduced the idea of constructing linkage maps of human genome based on restriction fragment length polymorphism (RFLP) markers. In recent years, the development of protein and DNA markers has stimulated interest for the new approaches to plant improvement. While classical maps based on morphological mutant markers have provided important insights into the plant genetics and cytology, the molecular maps based on molecular markers have a number of inherent advatages over classical genetic maps for the applications in genetic studies and/or breeding schemes. Isozymes and DNA markers are numerous, discrete, non-deleterious, codominant, and almost entirely free of environmental and epistatic interactions. For these reasons, they are widely used in constructing detailed linkage maps in a number of plant species. Plant breeders improve crops by selecting plants with desirable phenotypes. However a plant's phenotyes is often under genetic control, positioning at different "quantitative trait loci" (QTLs) together with environmental effects. Molecular maps provide a possible way to determine the effect of the individual gene that combines to produce a quantitative trait because the segregation of a large number of markers can be followed in a single genetic cross. Using market-assisted selection, plants that contain several favorable genes for the trait and do not contain unfavourable segments can be obtained during early breeding processes. Providing molecular maps are available, valuable data relevant to the taxonomic relationships and chromosome evolution can be accumulated by comparative mapping and also the structural relationships between linkage map and physical map can be identified by cDNA sequencing. After constructing high density maps, it will be possible to clone genes, whose products are unknown, such as semidwarf and disease resistance genes. However, much attention has to be paid to level-up the basic knowledge of genetics, physiology, biochemistry, plant pathology, entomology, microbiology, and so on. It must also be kept in mind that scientists in various fields will have to make another take off by intensive cooperation together for early integration and utilization of these newly emerging high-techs in practical breeding. breeding.

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차량측량시스템의 CCD 영상에 의한 3차원 위치결정 방법 비교 연구 (A Comparative Study on the 3D Positioning Methods by CCD Images of The Mobile Mapping System)

  • 정동훈
    • Spatial Information Research
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    • 제15권2호
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    • pp.169-180
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    • 2007
  • 정부 및 지자체 행정업무의 전산화와 통합시스템 구축이 증가함에 따라 차량측량시스템의 활용성이 점차 증대 돼 가고 있다. 이와 같은 요구에 따라 특정 지역의 시설물을 신속하게 측정해야 하는 경우가 발생하는데 이 경우에는 후처리방식보다는 실시간 현장처리방식이 필요하며 현장처리에 있어서는 정확도 못지않게 자료의 처리속도가 중요한 요소가 된다. 본 연구에서는 정확도와 처리속도 면에서 현장처리에 적합한 3차원 위치결정방법을 선정하기 위해 사진측량분야에서 사용되어 온 두 가지 공간전방교회법을 프로그램화하여 비교하였다. 특히, 해석적 공간전방교회법에 대해서는 기존의 근거리 지상사진 측량법을 차량의 이동에 따라 카메라의 위치와 자세가 변하는 차량측량시스템의 특성에 맞도록 수정하여 적용하였다. 비교결과, 정확도의 측면에서는 두 방법에서 차이가 거의 없었으나 계산에 소요되는 시간의 측면에서는 해석적 공간전방교회법이 약 1/3 정도로 나타났다.

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주요 로봇 개발 국가의 로봇 디자인 성향 비교연구 - 인터랙티브 맵핑을 중심으로 (Comparative Study in National Characteristics of Robot Design - with the focus on use of Interactive Mapping -)

  • 김형근;이건표;김상룡;박정미
    • 감성과학
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    • 제8권3호
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    • pp.303-312
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    • 2005
  • 본 연구의 목적은 로봇의 상용화, 어플리케이션 개발에 대한 이해를 높이고 로봇의 평가 척도 간 연관성 및 개발 트렌드 등을 짚어보는 데 있었다. 인터랙티브 맵핑을 통해, 113가지의 로봇 샘플 자료들을 로봇의 평가척도 7가지에 대해 다양한 배치가 가능하고 각각 아이템에 대한 상세 정보가 참조 가능하도록 구현하여, 시각적으로 보다 면밀한 분석이 가능하였다. 또한 인터랙티브 맵핑을 활용하여 국가별 로봇 개발 성향의 차이를 살펴본 결과, 크게 미국, 유럽의 성향과 일본, 한국의 성향으로 나눌 수 있었다. 미국과 유럽은 공통적으로 로봇을 '도구'라 여기고, 이러한 점이 평가 척도의 다양한 부분에서 반영되었음을 알 수 있었다. 일본, 한국의 경우 로봇을 '파트너' 혹은 '공존하는 관계'라고 여기고, 이러한 점을 만족시키도록 개발하고 있는 것을 발견할 수 있었다.

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Porcine LMNA Is a Positional Candidate Gene Associated with Growth and Fat Deposition

  • Choi, Bong-Hwan;Lee, Jung-Sim;Lee, Seung-Hwan;Kim, Seung-Chang;Kim, Sang-Wook;Kim, Kwan-Suk;Lee, Jun-Heon;Seong, Hwan-Hoo;Kim, Tae-Hun
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권12호
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    • pp.1649-1659
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    • 2012
  • Crosses between Korean and Landrace pigs have revealed a large quantitative trait loci (QTL) region for fat deposition in a region (89 cM) of porcine chromosome 4 (SSC4). To more finely map this QTL region and identify candidate genes for this trait, comparative mapping of pig and human chromosomes was performed in the present study. A region in the human genome that corresponds to the porcine QTL region was identified in HSA1q21. Furthermore, the LMNA gene, which is tightly associated with fat augmentation in humans, was localized to this region. Radiation hybrid (RH) mapping using a Sus scrofa RH panel localized LMNA to a region of 90.3 cM in the porcine genome, distinct from microsatellite marker S0214 (87.3 cM). Two-point analysis showed that LMNA was linked to S0214, SW1996, and S0073 on SSC4 with logarithm (base 10) of odds scores of 20.98, 17.78, and 16.73, respectively. To clone the porcine LMNA gene and to delineate the genomic structure and sequences, including the 3'untranslated region (UTR), rapid amplification of cDNA ends was performed. The coding sequence of porcine LMNA consisted of 1,719 bp, flanked by a 5'UTR and a 3'UTR. Two synonymous single nucleotide polymorphisms (SNPs) were identified in exons 3 and 7. Association tests showed that the SNP located in exon 3 (A193A) was significantly associated with weight at 30 wks (p<0.01) and crude fat content (p<0.05). This association suggests that SNPs located in LMNA could be used for marker-assisted selection in pigs.

신경망 분류기와 선형트리 분류기에 의한 영상인식의 비교연구 (A Comparative Study of Image Recognition by Neural Network Classifier and Linear Tree Classifier)

  • Young Tae Park
    • 전자공학회논문지B
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    • 제31B권5호
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    • pp.141-148
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    • 1994
  • Both the neural network classifier utilizing multi-layer perceptron and the linear tree classifier composed of hierarchically structured linear discriminating functions can form arbitrarily complex decision boundaries in the feature space and have very similar decision making processes. In this paper, a new method for automatically choosing the number of neurons in the hidden layers and for initalzing the connection weights between the layres and its supporting theory are presented by mapping the sequential structure of the linear tree classifier to the parallel structure of the neural networks having one or two hidden layers. Experimental results on the real data obtained from the military ship images show that this method is effective, and that three exists no siginificant difference in the classification acuracy of both classifiers.

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Molecular Co-evolution of Gonadotropin-releasing Hormones and Their Receptors

  • Seong, Jae-Young;Kwon, Hyuk-Bang
    • Animal cells and systems
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    • 제11권2호
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    • pp.93-98
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    • 2007
  • Gonadotropin-releasing hormone (GnRH), synthesized in the hypothalamus, plays a pivotal role in the regulation of vertebrate reproduction. Since molecular isoforms of GnRH and their receptors (GnRHR) have been isolated in a broad range of vertebrate species, GnRH and GnRHR provide an excellent model for understanding the molecular co-evolution of a peptide ligand-receptor pair. Vertebrate species possess multiple forms of GnRH, which have been created through evolutionary mechanisms such as gene/chromosome duplication, gene deletion and modification. Similar to GnRHs, GnRH receptors (GnRHR) have also been diversified evolutionarily. Comparative ligand-receptor interaction studies for non-mammalian and mammalian GnRHRs combined with mutational mapping studies of GnRHRs have aided the identification of domains or motifs responsible for ligand binding and receptor activation. Here we discuss the molecular basis of GnRH-GnRHR co-evolution, particularly the structure-function relationship regarding ligand selectivity and signal transduction of mammalian and non-mammalian GnRHRs.

The Design Methodology of Fuzzy Controller by Means of Evolutionary Computing and Fuzzy-Set based Neural Networks

  • Roh, Seok-Beom;Oh, Sung-Kwun
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2004년도 춘계학술대회 학술발표 논문집 제14권 제1호
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    • pp.438-441
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    • 2004
  • In this study, we introduce a noble neurogenetic approach to the design of fuzzy controller. The design procedure dwells on the use of Computational Intelligence (CI), namely genetic algorithms and Fuzzy-Set based Neural Networks (FSNN). The crux of the design methodology is based on the selection and determination of optimal values of the scaling factors of the fuzzy controllers, which are essential to the entire optimization process. First, the tuning of the scaling factors of the fuzzy controller is carried out by using GAs, and then the development of a nonlinear mapping for the scaling factors is realized by using GA based FSNN. The developed approach is applied to a nonlinear system such as an inverted pendulum where we show the results of comprehensive numerical studies and carry out a detailed comparative analysis.

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A Comparative Study on Star Formation of Barred and Unbarred Disk Galaxies from SDSS-IV MaNGA IFU survey

  • 지웅배;윤석진
    • 천문학회보
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    • 제42권2호
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    • pp.77.2-77.2
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    • 2017
  • We investigate star formation activities of ~400 barred and unbarred faced-on late-type galaxies from the SDSS-IV MaNGA (Mapping Nearby Galaxies at APO) IFU survey. We find the star formation activities in gas-poor, barred galaxies are considerably suppressed than gas-rich, barred galaxies, while there is no difference among unbarred galaxies regardless of their HI gas content. The gas-poor and barred galaxies show the steeper difference of gradient in metallicity and age with respect to the stellar mass than gas-rich or unbarred galaxies, in that their centre is more metal-rich and younger. The results suggest that, combined with the gas contents available, the bar structure plays a significant role in quenching star formation in a galaxy by transporting/mixing gas via gas inflow.

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Analysis of Reference Inquiries in the Field of Social Science in the Collaborative Reference Service Using the Co-Word Technique

  • 조재인
    • 한국문헌정보학회지
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    • 제49권1호
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    • pp.129-148
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    • 2015
  • This study grasped the true nature of the inquiry domain by analysing the requests for collaborative reference service in the social science field using the co-word technique, and schematized the intellectual structure. First, this study extracted 748 uncontrolled keywords from inquiries for reference in the field of social science. Second, calculated similarity indices between the words on the basis of co-occurrence frequency, and performed not only clustering but also MDS mapping. Third, to grasp the difference in inquiries for reference by period, dividing the period into two parts, and performed comparative analysis. As a result, there formed 5 clusters and "Korea Education" showed an overwhelming size with 40.3% among those clusters. The result of the analysis through the period division showed there were many questions about "Education" during the first half, while a lot of inquiries with focus on "welfare and business information" during the second half.