• 대한의생명과학회지
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• 제11권4호
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• pp.525-531
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• 2005

Staphylococcus aureus is a major cause of nosocomial infections and is one of the most commonly isolated bacterial species in the hospital and continues to be an important pathogen in both community and hospital-acquired infection. Methicillin resistant S. aureus (MRSA), which is associated with hospitals is now being isolated in the community. The purpose of this study is to investigate the carrier rate of S. aureus in the community, antibiotic resistance patterns of the organism, detection of MRSA and mecA gene in MRSA. Ninety strains $(46.4\%)$ of S. aureus were isolated from the nasal specimens of 194 elementary school students. Eighty-nine strains $(98.9\%)$ of 90 S. aureus were resistant to penicilin, 36 strains $(40.0\%)$ to erythromycin, 14 strains $(15.6\%)$ to fusidic acid, 11 strains $(12.2\%)$ to gentamycin, 9 strains $(10.0\%)$ to tobramycin, 5 strains $(5.6\%)$ to oxacillin, 4 strains $(4.4\%)$ to clindamycin, 2 strains $(2.2\%)$ to tetracycline, 1 strains $(1.1\%)$ to fosfomycin. None of $90(0\%)$ S. aureus isolates was resistant to ciprpfloxacin, trimethoprim/sulfamethoxazole, levofloxacin, linezolid, moxifloxacin, nitrofurantoin, norfloxacin, rifampicin, quinupristin/dalfopristin, teicoplanin, and vancomycin. Five strains $(5.6\%)$ of 90 S. aureus isolates were MRSA. The mecA gene was detected from five MRSA strains by PCR.

• 상하수도학회지
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• 제26권6호
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• pp.767-777
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• 2012

Annular Biofilm Reactor (ABR) equipped with coupons of three different pipe materials (STS 304, PVC, PE) was used to generate drinking water biofilm samples. The level of assimilable organic carbon (AOC) during the sample generation period was $37.3{\mu}g/L$, and this level did not seem to be low enough to limit the formation of biofilm in this study. Terminal-restriction fragment length polymorphism (T-RFLP) analyses determined T-RF profile as early as 3 h of exposure on PVC coupons. Average surface roughness ($R_a$) measured by atomic force microscopic analyses was 125.7 nm for PVC, and this value was higher than for STS (71.6 nm) and PE (74.0 nm). However, biofilm formation was faster on STS (6 h) than on PE (12 h), which indicated that surface roughness might not be the only factor that controlled the initiation of biofilm development. Upon detection of the T-RF peaks, richness (S) and diversity indices such as Shannon (H) and Simpson (1/D) demonstrated a rather slow increase until 48 h followed by rapid increase regardless of the pipe materials. Differences of microbial community structures among the biofilm samples were determined based on the cluster analysis using Jaccard coefficients (Sj). Biofilm communities could be divided into two distinct groups according to the exposure time regardless of the pipe materials. First group contained a young (< 48 h) biofilm samples (10 out of 11) but second group contained a mature (${\geq}$ 48 h) samples (11 out of 14). Results suggested that, due to the complexity of biofilm, the targeting of the first group of cluster was crucial for optimizing the management of drinking water distribution systems and controlling microbial growth.

• 한국통신학회논문지
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• 제38B권1호
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• pp.87-96
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• 2013

사회 관계망에서 영향력의 전파는 중요한 연구 이슈이다. 영향 전파는 임의의 노드로 부터 새로운 아이디어, 정보, 소문의 전파로 인해 다른 노드들의 상태나 성질이 변화하는 것을 뜻한다. 영향을 받은 노드는 자신과 통신하는 다른 노드에게도 영향을 주고 영향은 확산되어 네트워크 내에서 퍼져 나간다. 입소문 마케팅에 기반을 둔 영향력 전파 문제는 네트워크에 가장 영향력을 끼칠 수 있는 노드들을 찾아 전체 네트워크에 영향력을 최대화 하는 것이 목적이다. 본 논문에서는 Delay-Tolerant Networks에서 각 노드의 영향력을 측정하여 가장 영향력 있는 노드 집합을 선택하는 문제를 다룬다. 노드 간 연결성이 항시 보장되지 않는 Delay-Tolerant Networks 환경에서는 전체 네트워크 정보를 정확히 알 수 없기 때문에 노드의 영향력을 정확히 측정하는 것은 쉽지 않다. 본 논문에서는 Delay-Tolerant Networks 환경에서 분산 방식으로 각자 노드가 $k$-clique 구조로 커뮤니티를 구성하여 한정된 지역 정보만을 활용하여 자신의 영향력을 추정하는 방법을 제시한다. 또한, 실험을 통해 제안 기법으로 산출한 영향력 있는 노드 정보가 전체 네트워크 관점에서 산출한 영향력 있는 노드 정보와 거의 일치함을 보인다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8479-8486
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• 2016

Background: Colorectal cancer (CRC) is the third most common cancer globally. In Jordan, it is the number one cancer among men and the second most common cancer among women, accounting for 15% and 9.4% respectively of all male and female diagnosed cancers. This study aimed to evaluate the knowledge and perceptions about colorectal cancer risk factors, signs and symptoms in Jordan and to provide useful data about the best modes of disseminating preventive messages about the disease. Materials and Methods: A stratified clustered random sampling technique was used to recruit 300 males and 300 females aged 30 to 65 years without a previous history of CRC from four governorates in Jordan. A semi-structured questionnaire and face to face interviews were employed. Descriptive and multivariate analysis was applied to assess knowledge and perceptions about CRC. Results: Both males and females perceived their CRC risk to be low. They had low knowledge scores about CRC with no significant gender association (P=0.47). From a maximum knowledge score of 18 points, the median scores of males and females were 4 points (SD=2.346, range 0-13) and 4 points (SD=2.329, range 0-11) respectively. Better knowledge scores were associated with governorate, higher educational level, older age, higher income, having a chronic disease, having a family history of CRC, previously knowing someone who had CRC and their doctor's knowledge about their family history of CRC. Conclusions: There is a low level of knowledge about CRC and underestimation of risk among the study participants. This underlines the need for public health interventions to create awareness about the illness. It also calls for further research to assess the knowledge and perceptions about CRC early detection examinations in Jordan.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3095-3099
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• 2016

Background: Cervical cancer is the most frequently diagnosed cancer among women in India. Understanding quality of life (QOL) in women undergoing chemo-radiotherapy for cervical cancer will help in introducing interventions for better care and outcomes in these women. This study assessed QOL before and after chemo-radiotherapy in cervical cancer patients. Materials and Methods: This follow-up study covered sixty-seven newly diagnosed women with advanced cervical cancer (stages 2b to 4b). Structured questionnaires (the European Organization for Research and Treatment of Cancer, EORTC QLQ-C30 and EORTC QLQ-CX24) were used to assess the change in QOL after 6 months of treatment. Results: The mean age of women at the time of detection of cervical cancer was $52.3{\pm}11.29$ years (Range 30-75 years). Six months survival was 92.53%. The mean global health score of cervical cancer patients after six months of treatment was 59.52, which was significantly higher than the pre-treatment score of 50.15 (p=0.00007). Physical, cognitive and emotional functioning improved significantly (p<0.05) after treatment. Fatigue, pain, insomnia and appetite loss improved but episodes of diarrhea increased after treatment. The mean "symptoms score" using EORTC QLQ-CX24 post treatment was 20.0 which was significantly lower as compared to the pre- treatment score 30.0 (p<0.00001). Sexual enjoyment and sexual functioning decreased significantly after treatment. Conclusions: QOL of newly diagnosed cervical cancer patients improved significantly following chemo-radio therapy. Enhancement was also demonstrated on three of the five functional scales of EORTC QLQ-C30. To further improve QOL, interventions focusing on social and psychological support and physical rehabilitation may be needed.

• Journal of Community Nutrition
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• 제8권2호
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• pp.107-113
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• 2006

Sensory factors are important determinants of appetite and food choices but little is known about factors affecting taste acuity and preference of Koreans. Any factors causing deficits in sweet taste perception may lead to over consumption of simple sugar, which is related to several chronic diseases. This study was conducted to determine factors affecting sweet taste sensitivity and preference. Subjects were 30 government employees who were serving as school dietitians or in the area of public health while they were studying in the program for the qualification to become nutrition teachers. Sweet taste threshold and the optimally-preferred sweetness of omija jelly were determined by a sensory evaluation and general characteristics, health-related lifestyles, dietary habits and food preferences were determined using a self-administered questionnaire. For the subjects of this study, detection threshold concentration of sucrose solution was $0.184{\pm}0.06%$ and optimally-preferred sucrose concentration of omija jelly was $13.88{\pm}2.28%$ and there was no significant correlation between the sweet taste sensitivity and preference. Subjects who had higher(${\ge}4$ out of 10) physical or psychological stress and who had late getting-up time (after 7am) tended to have lower sweet taste threshold (higher sensitivity) than their counterpart. The sweet taste preference determined by optimally-preferred sucrose concentration of omija jelly tended to be lower in the subjects who eat slowly. Those who answered in the questionnaire to prefer sweet foods did have significantly higher optimally-preferred sucrose concentration of omija jelly. Further research is required to determine whether decreased sensitivity and increased preference for sweetness can increase the actual intake of simple sugar. (J Community Nutrition 8(2): 107 -113, 2006)

• 한국컴퓨터정보학회논문지
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• 제13권2호
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• pp.51-57
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• 2008

본 논문에서는 주파수 할당의 최적화를 위하여 제약만족문제의 모델링과 백트랙킹 탐색의 경험적 알고리즘을 제안한다. 연구의 목적은 주어진 서비스 영역에서 공동체 라디오 방송국의 개수를 최대화하면서 동시에 필요주파수를 최소화시키는 제약조건을 만족하는 주파수 할당이다. 본 연구는 효과적으로 해를 찾기 위하여 경험적 알고리즘을 제안하는데, 이것은 제한된 시간 안에 해를 찾는데 필요한 백트랙킹 횟수를 최소화하는 변수 순서와 값 순서에 관한 방법이다. 백트랙킹에서 불일치성을 늦게 발견하는 문제를 보완하기 위해서 일관성 강화기술 또는 제약 전파 방법을 사용한다. 백트랙킹 탐색과 일관성 강화 기술을 함게 사용함으로써 제약만족문제에 관한 보다 강력하고 효과적인 알고리즘을 얻을 수 있다. 본 논문은 또한 계산된 해와 이론적인 하한 값을 비교함으로써 제안된 알고리즘의 성능 비교를 수행한다.

• Neonatal Medicine
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• 제28권3호
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• pp.124-132
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• 2021

Purpose: Neonatal near miss (NNM) allows for the detection of risk factors associated with serious newborn complications and death, the prevention of which could reduce neonatal mortality. This study was conducted with the objective of identifying predictors for NNM in a tertiary hospital in Bangalore city. Methods: This was an unmatched case-control study involving 120 NNM cases and 120 controls. NNM was determined using Pileggi-Castro's pragmatic and management criteria. Data was collected from in-patient hospital records and interviews of postpartum mothers. Multiple logistic regression of exposure variables was performed to calculate adjusted odds ratio (AOR) with 95% confidence interval (CI). Results: Significant predictors were maternal age ≥30 years (AOR, 5.32; 95% CI, 1.12 to 9.29; P=0.041), inadequate antenatal care (ANC) (AOR, 8.35; 95% CI, 1.98 to 51.12; P=0.032), <3 ultrasound scans during pregnancy (AOR, 12.5; 95% CI, 1.60 to 97.27; P=0.016), maternal anaemia (AOR, 18.96; 95% CI, 3.10 to 116.02; P=0.001), and any one obstetric complication (hypertensive disorder in pregnancy, diabetes in pregnancy, preterm premature rupture of membranes, prolonged labour, obstructed labour, malpresentation) (AOR, 4.34; 95% CI, 1.26 to 14.95; P=0.02). Conclusion: The predictors of NNM identified has important implications for public health policy and practice whose modifications can improve NNM. These include expanding essential ANC package to include ultrasound scans, ensuring World Health Organization recommendations of eight ANC visits, capacity building at all levels of health care to strengthen routine ANC and obstetric care for effective screening, referral and management of obstetric complications.

• Healthcare Informatics Research
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• 제24권4호
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• pp.300-308
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• 2018

Objectives: Prompt detection is a cornerstone in the control and prevention of infectious diseases. The Integrated Disease Surveillance Project of India identifies outbreaks, but it does not exactly predict outbreaks. This study was conducted to assess temporal correlation between Google Trends and Integrated Disease Surveillance Programme (IDSP) data and to determine the feasibility of using Google Trends for the prediction of outbreaks or epidemics. Methods: The Google search queries related to malaria, dengue fever, chikungunya, and enteric fever for Chandigarh union territory and Haryana state of India in 2016 were extracted and compared with presumptive form data of the IDSP. Spearman correlation and scatter plots were used to depict the statistical relationship between the two datasets. Time trend plots were constructed to assess the correlation between Google search trends and disease notification under the IDSP. Results: Temporal correlation was observed between the IDSP reporting and Google search trends. Time series analysis of the Google Trends showed strong correlation with the IDSP data with a lag of -2 to -3 weeks for chikungunya and dengue fever in Chandigarh (r > 0.80) and Haryana (r > 0.70). Malaria and enteric fever showed a lag period of -2 to -3 weeks with moderate correlation. Conclusions: Similar results were obtained when applying the results of previous studies to specific diseases, and it is considered that many other diseases should be studied at the national and sub-national levels.

• 한국산학기술학회논문지
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• 제10권4호
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• pp.811-817
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• 2009

IT 시스템 기반의 네트워크 환경의 급속한 발전은 지속적인 연구방향의 중요한 이슈의 결과이다. 침입시도 탐지는 관심분야의 하나인 것이다. 최근에 다양한 기술을 기반으로 하는 침입시도탐지들이 제안되고 있으나 이러한 기술은 여러 형태의 침입시도의 패턴 중에 한가지 형태 및 시스템에 적용이 가능한 것이다. 또한 새로운 형태 침입시도를 탐지하지 못하고 있다. 그러므로 새로운 형태를 인식하는 침입탐지 관련 기술이 요구되어 지고 있다. 본 연구에서는 퍼지인식도와 비정상 트래픽 분석을 이용한 네트워크 기반의 침입탐지기법(NePID)을 제안한다. 이 제안은 패킷 분석을 통하여 서비스거부공격과 유사한 침입시도를 탐지하는 것이다. 서비스거부공격은 침입시도의 형태를 나타내며 대표적인 공격으로는 syn flooding 공격이 있다 제안한 기법은 syn flooding을 탐지하기 위하여 패킷정보를 수집 및 분석한다. 또한 피지인식도와 비정상 트래픽 분석을 적용하여 판단모듈의 분석 결과를 토대로 기존의 서비스 거부 공격의 탐지 툴과의 비교분석을 하였으며 실험데이터로는 MIT Lincoln 연구실의 IDS 평가데이터 (KDD'99)를 이용하였다. 시뮬레이션 결과 최대평균 positive rate는 97.094% 탐지율과 negative rate는 2.936%을 얻었으며 이 결과치는 KDD'99의 우승자인 Bernard의 결과치와 유사한 수준의 값을 나타내었다.