Browse > Article
http://dx.doi.org/10.5385/nm.2021.28.3.124

A Case-Control Study on the Predictors of Neonatal Near-Miss: Implications for Public Health Policy and Practice  

Johnson, Avita Rose (Department of Community Health, St. John's Medical College)
Sunny, Sobin (Department of Community Medicine, Al Azhar Medical College and Super Speciality Hospital)
Nikitha, Ramola (St. John's Medical College)
Thimmaiah, Sulekha (Department of Community Health, St. John's Medical College)
Rao, Suman P.N. (Department of Neonatology, St. John's Medical College)
Publication Information
Neonatal Medicine / v.28, no.3, 2021 , pp. 124-132 More about this Journal
Abstract
Purpose: Neonatal near miss (NNM) allows for the detection of risk factors associated with serious newborn complications and death, the prevention of which could reduce neonatal mortality. This study was conducted with the objective of identifying predictors for NNM in a tertiary hospital in Bangalore city. Methods: This was an unmatched case-control study involving 120 NNM cases and 120 controls. NNM was determined using Pileggi-Castro's pragmatic and management criteria. Data was collected from in-patient hospital records and interviews of postpartum mothers. Multiple logistic regression of exposure variables was performed to calculate adjusted odds ratio (AOR) with 95% confidence interval (CI). Results: Significant predictors were maternal age ≥30 years (AOR, 5.32; 95% CI, 1.12 to 9.29; P=0.041), inadequate antenatal care (ANC) (AOR, 8.35; 95% CI, 1.98 to 51.12; P=0.032), <3 ultrasound scans during pregnancy (AOR, 12.5; 95% CI, 1.60 to 97.27; P=0.016), maternal anaemia (AOR, 18.96; 95% CI, 3.10 to 116.02; P=0.001), and any one obstetric complication (hypertensive disorder in pregnancy, diabetes in pregnancy, preterm premature rupture of membranes, prolonged labour, obstructed labour, malpresentation) (AOR, 4.34; 95% CI, 1.26 to 14.95; P=0.02). Conclusion: The predictors of NNM identified has important implications for public health policy and practice whose modifications can improve NNM. These include expanding essential ANC package to include ultrasound scans, ensuring World Health Organization recommendations of eight ANC visits, capacity building at all levels of health care to strengthen routine ANC and obstetric care for effective screening, referral and management of obstetric complications.
Keywords
Case-control studies; Neonatal near-miss; Infant mortality; Infant, newborn; Risk factors;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Ninama NH, Shroff BD. Will outlining neonatal near miss events make a change?: a hospital based case control study. Int J Community Med Public Health 2019;6:4570-4.   DOI
2 World Health Organization. New guidelines on antenatal care for a positive pregnancy experience [Internet]. Geneva: WHO; 2016 [cited 2021 Aug 5]. Available from: https://www.who.int/reproductivehealth/news/antenatal-care/en/.
3 Kale PL, Mello-Jorge MH, Silva KS, Fonseca SC. Neonatal near miss and mortality: factors associated with life-threatening conditions in newborns at six public maternity hospitals in Southeast Brazil. Cad Saude Publica 2017;33:e00179115.
4 International Institute for Population Sciences. National Family Health Survey (NFHS-4) 2015-16 [Internet]. Mumbai: International Institute for Population Sciences (IIPS) and ICF; 2017 [cited 2021 Aug 5]. Available from: http://rchiips.org/NFHS/NFHS-4Reports/India.pdf.
5 Pileggi-Castro C, Camelo JS Jr, Perdona GC, Mussi-Pinhata MM, Cecatti JG, Mori R, et al. Development of criteria for identifying neonatal near-miss cases: analysis of two WHO multicountry cross-sectional studies. BJOG 2014;121 Suppl 1:110-8.   DOI
6 UNICEF data. Levels and trends in child mortality 2014 [Internet]. New York: United Nations Children's Fund; 2014 [cited 2021 Aug 5]. Available from: https://data.unicef.org/resources/levelstrends-child-mortality-report-2014.
7 Santos JP, Cecatti JG, Serruya SJ, Almeida PV, Duran P, Mucio Bd, et al. Neonatal near miss: the need for a standard definition and appropriate criteria and the rationale for a prospective surveillance system. Clinics (Sao Paulo) 2015;70:820-6.   DOI
8 de Lima TH, Katz L, Kassar SB, Amorim MM. Neonatal near miss determinants at a maternity hospital for high-risk pregnancy in Northeastern Brazil: a prospective study. BMC Pregnancy Childbirth 2018;18:401.   DOI
9 Pandey VK, Pradeep A, Rakesh K. Modified BG prasads socioeconomic classification-2018: the need of an update in the present scenario. Indian J Community Health 2018;30:82-4.   DOI
10 Allendorf K. The quality of family relationships and use of maternal health-care services in India. Stud Fam Plann 2010;41:263-76.   DOI
11 Mammaro A, Carrara S, Cavaliere A, Ermito S, Dinatale A, Pappalardo EM, et al. Hypertensive disorders of pregnancy. J Prenat Med 2009;3:1-5.
12 Indian Institute for Population Sciences and Ministry of Health and Family Welfare. National Family Health Survey-4 (2015-16) [Internet]. New Delhi; Government of India; 2017 [cited 2021 Aug 5]. Available from: http://rchiips.org/nfhs/pdf/NFHS4/India.pdf.
13 Centers for Disease Control and Prevention. Diabetes during pregnancy [Internet]. Atlanta: CDC; 2018 [cited 2021 Aug 5]. Available from: https://www.cdc.gov/reproductivehealth/maternalinfanthealth/diabetes-during-pregnancy.htm.
14 Dolea C, AbouZahr C. Global burden of obstructed labour in the year 2000 [Internet]. Geneva: World Health Organization; 2003 [cited 2021 Aug 5]. Available from: https://www.who.int/healthinfo/statistics/bod_obstructedlabour.pdf.
15 Santos JP, Pileggi-Castro C, Camelo JS Jr, Silva AA, Duran P, Serruya SJ, et al. Neonatal near miss: a systematic review. BMC Pregnancy Childbirth 2015;15:320.   DOI
16 Kahveci B, Melekoglu R, Evruke IC, Cetin C. The effect of advanced maternal age on perinatal outcomes in nulliparous singleton pregnancies. BMC Pregnancy Childbirth 2018;18:343.   DOI
17 Titaley CR, Dibley MJ, Roberts CL, Hall J, Agho K. Iron and folic acid supplements and reduced early neonatal deaths in Indonesia. Bull World Health Organ 2010;88:500-8.   DOI
18 Prashantha YN, Shashidhar A, Balasunder BC, Kumar BP, Rao PN. Onsite mentoring of special newborn care unit to improve the quality of newborn care. Indian J Public Health 2019;63:357-61.   DOI
19 Drennan KJ, Blackwell S, Sokol RJ. Abnormal labor: diagnosis and management. Glob Libr Women Med 2008. https://www.glowm.com/section_view/heading/abnormal-labordiagnosis-and-management/item/132.
20 World Health Organization. Guideline: Daily iron and folic acid supplementation in pregnant women [Internet]. Geneva: WHO; 2012 [cited 2021 Aug 5]. Available from: https://apps.who.int/iris/bitstream/handle/10665/77770/9789241501996_eng.pdf;jsessionid=9EF80D14B856F9F330E3C97092039512?sequence=1.
21 Medina TM, Hill DA. Preterm premature rupture of membranes: diagnosis and management. Am Fam Physician 2006;73:659-64.
22 Sharshiner R, Silver RM. Management of fetal malpresentation. Clin Obstet Gynecol 2015;58:246-55.   DOI
23 Nakimuli A, Mbalinda SN, Nabirye RC, Kakaire O, Nakubulwa S, Osinde MO, et al. Still births, neonatal deaths and neonatal near miss cases attributable to severe obstetric complications: a prospective cohort study in two referral hospitals in Uganda. BMC Pediatr 2015;15:44.   DOI
24 Londero AP, Rossetti E, Pittini C, Cagnacci A, Driul L. Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study. BMC Pregnancy Childbirth 2019;19:261.   DOI
25 O'Hare B, Makuta I, Chiwaula L, Bar-Zeev N. Income and child mortality in developing countries: a systematic review and meta-analysis. J R Soc Med 2013;106:408-14.   DOI
26 Tekelab T, Chojenta C, Smith R, Loxton D. Incidence and determinants of neonatal near miss in south Ethiopia: a prospective cohort study. BMC Pregnancy Childbirth 2020;20: 354.   DOI
27 Vogel JP, Souza JP, Mori R, Morisaki N, Lumbiganon P, Laopaiboon M, et al. Maternal complications and perinatal mortality: findings of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 2014;121 Suppl 1:76-88.   DOI
28 Sustainable Development Goals. SDG 3: Ensure healthy lives and promote wellbeing for all at all ages [Internet]. Geneva: World Health Organization; 2020 [cited 2021 Aug 5]. Available from: https://www.who.int/sdg/targets/en/.
29 UNICEF data. Country Profile: India [Internet]. New York: United Nations Children's Fund; 2020 [cited 2021 Aug 5]. Available from: https://data.unicef.org/country/ind/.
30 India State-Level Disease Burden Initiative Child Mortality Collaborators. Subnational mapping of under-5 and neonatal mortality trends in India: the Global Burden of Disease Study 2000-17. Lancet 2020;395:1640-58.   DOI
31 Ministry of Health and Family Welfare Government of India. India Newborn Action Plan [Internet]. New Delhi: Government of India; 2014 [cited 2021 Aug 5]. Available from: https://www.newbornwhocc.org/INAP_Final.pdf.